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The map label for this gene is sglT [H]

Identifier: 92112390

GI number: 92112390

Start: 290655

End: 292283

Strand: Direct

Name: sglT [H]

Synonym: Csal_0255

Alternate gene names: 92112390

Gene position: 290655-292283 (Clockwise)

Preceding gene: 92112387

Following gene: 92112391

Centisome position: 7.86

GC content: 64.95

Gene sequence:

>1629_bases
GTGAGCGAGTTTACCTGGCTGGATAGCGTCGTCTTGGTGGTGTACATCCTGCTCGTGGCGCTGATAGGCGCGCGTTTCGG
GCGGAGCCAGCAGAGTACCCAGGATTATTTCCTGGGCGGTCGGCGAATTCCCGGCTGGGCGATCGGGCTGTCGGTGATGG
CGACCCAGGCCAGCGCGATCACCTTCATCGGCGCTCCCGGCTGGGGGTTCGAGGGCGGCCTGGAGCGGCTGGTGACGTTC
CTCAACGTGCCGCTGGCGATGGCGGTGCTGATCTTTCTGCTGGTGCCCGTGTTTCATCGCGCGGGCATCTACAGCATCTA
CGAGCTTCTCGAGCGTCGCTTCGGGCCGGCCACGCGCAGCGTGAGCGCAGGTCTGTTCCTGGTGGCACGCGGCCTGGCGA
CCGGCGTGGTGCTTTATGCGCCGGCACTGGTGCTCTCGGTGGTGACCGGCTGGAGCGTCAACCTGACCATCGTGGTCATG
GCGGTGCTGGCGGTGAGCTACACGGTGCTGGGCGGTATCAGTGCAGTGATCTGGACCGACGTGATCCAGATGTTCGTGCT
GTGGCTGGGCGCCCTGGTCAGCATGGGATTGATGGTGGCGAGTCTGCCCGGTGGCTGGAGCGATGTCTTTGCCTTCGGTG
CAGCACAGGGGATGTTCGACACCCTGGACCTGTCGCTGGACCCCGGGGTGACTTATTCGCTGTGGGCCGGCCTGTTCGGC
GGCATCTTCCTGCATATCGCGTATTTCGGCACCGACCAGAGCCAGATTCAGCGGGTCCTGACCAGCCCCGATGTGCAGCA
GGGACAGCGCTCACTGTTGATCGGCGGGTACCTGCTGGTGCCGCAGATGTTGCTGTTCTTGTTCATCGGGGTGATGTTGG
CGACCTACTACGACCAGCACGGCCTTGCCGCGCCGGACAACCTCAACGAGCTGTTCCCGCGCTATGTGGTCAGCGCCTTT
CCGCCGGGTCTGGCCGGTCTGGTGATTGCCGGTGTCTTCGCGGCGGCGATGTCGAGTCTCGACTCGGCGCTCAATTCGCT
GTCGGCGGTGAGCGTGCGCGATTTCTATACGCGATATGTCAGGCCCGACGCCAGCGAGGCGCATTATCTCAAGGCCTCGC
GCTGGGCGACGGTCTTCTGGGGCCTGTATGCGACGGTCTTCGCGTTCTTCGCCGGTAACCTGGGGCCGGTGATCGAGGCG
GTCAATCGTATCGGGTCCTGGTTCTACGGCGCCCTGCTGGGCACCTTCCTGCTGGCCATGCTCAGCCATCGCACCAATGC
CCGCGGTGCGCTGAGCGGCCTGGTGCTGGGCATGGTCTCGGTGTGGGGCGTCGAAAGCCTCTTCGATATCTCCTGGCTTT
ACAACAATCTGGTGGGAGTGGTGGTGTCGCTCGGCGTAGGGTATGTCGTCGGTCTGACGGCGCCTGCCCCGAGCGCGGCG
CAATTGCGCGACGTGGTCATCGAGGAAACCGCCCCGGATATGCAGGCGTTGCTGGCGACGCGCGCCGCCCGTGCCCGGTC
GATCACGCCGGCGGCACGCCTGACACGTCGCCGCTGTATCGGGCTGGTGGCATGGTTCTGTCTGTTGCTGGCGGGTCTGG
CACTGTTGCAGGGGTGGGCCAATGCCTGA

Upstream 100 bases:

>100_bases
ATGCGATTCGGGACCGGACGGCACCCATGGCGTGCCGATCGGCAGCCTGGAAAGAAGCCTGCTAATTTGGATAGCCAGGT
GGATCACAAAGGGGCGGGTC

Downstream 100 bases:

>100_bases
GGCGCTTCCCCTGAGACTGCCTCGGCGACTCGATGCCCTGCAGGCCGAGACGCGCCTGCGTCGCCTGCGCGCCGAGACCT
TCGAGGCGGCGACGCTCACG

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MSEFTWLDSVVLVVYILLVALIGARFGRSQQSTQDYFLGGRRIPGWAIGLSVMATQASAITFIGAPGWGFEGGLERLVTF
LNVPLAMAVLIFLLVPVFHRAGIYSIYELLERRFGPATRSVSAGLFLVARGLATGVVLYAPALVLSVVTGWSVNLTIVVM
AVLAVSYTVLGGISAVIWTDVIQMFVLWLGALVSMGLMVASLPGGWSDVFAFGAAQGMFDTLDLSLDPGVTYSLWAGLFG
GIFLHIAYFGTDQSQIQRVLTSPDVQQGQRSLLIGGYLLVPQMLLFLFIGVMLATYYDQHGLAAPDNLNELFPRYVVSAF
PPGLAGLVIAGVFAAAMSSLDSALNSLSAVSVRDFYTRYVRPDASEAHYLKASRWATVFWGLYATVFAFFAGNLGPVIEA
VNRIGSWFYGALLGTFLLAMLSHRTNARGALSGLVLGMVSVWGVESLFDISWLYNNLVGVVVSLGVGYVVGLTAPAPSAA
QLRDVVIEETAPDMQALLATRAARARSITPAARLTRRRCIGLVAWFCLLLAGLALLQGWANA

Sequences:

>Translated_542_residues
MSEFTWLDSVVLVVYILLVALIGARFGRSQQSTQDYFLGGRRIPGWAIGLSVMATQASAITFIGAPGWGFEGGLERLVTF
LNVPLAMAVLIFLLVPVFHRAGIYSIYELLERRFGPATRSVSAGLFLVARGLATGVVLYAPALVLSVVTGWSVNLTIVVM
AVLAVSYTVLGGISAVIWTDVIQMFVLWLGALVSMGLMVASLPGGWSDVFAFGAAQGMFDTLDLSLDPGVTYSLWAGLFG
GIFLHIAYFGTDQSQIQRVLTSPDVQQGQRSLLIGGYLLVPQMLLFLFIGVMLATYYDQHGLAAPDNLNELFPRYVVSAF
PPGLAGLVIAGVFAAAMSSLDSALNSLSAVSVRDFYTRYVRPDASEAHYLKASRWATVFWGLYATVFAFFAGNLGPVIEA
VNRIGSWFYGALLGTFLLAMLSHRTNARGALSGLVLGMVSVWGVESLFDISWLYNNLVGVVVSLGVGYVVGLTAPAPSAA
QLRDVVIEETAPDMQALLATRAARARSITPAARLTRRRCIGLVAWFCLLLAGLALLQGWANA
>Mature_541_residues
SEFTWLDSVVLVVYILLVALIGARFGRSQQSTQDYFLGGRRIPGWAIGLSVMATQASAITFIGAPGWGFEGGLERLVTFL
NVPLAMAVLIFLLVPVFHRAGIYSIYELLERRFGPATRSVSAGLFLVARGLATGVVLYAPALVLSVVTGWSVNLTIVVMA
VLAVSYTVLGGISAVIWTDVIQMFVLWLGALVSMGLMVASLPGGWSDVFAFGAAQGMFDTLDLSLDPGVTYSLWAGLFGG
IFLHIAYFGTDQSQIQRVLTSPDVQQGQRSLLIGGYLLVPQMLLFLFIGVMLATYYDQHGLAAPDNLNELFPRYVVSAFP
PGLAGLVIAGVFAAAMSSLDSALNSLSAVSVRDFYTRYVRPDASEAHYLKASRWATVFWGLYATVFAFFAGNLGPVIEAV
NRIGSWFYGALLGTFLLAMLSHRTNARGALSGLVLGMVSVWGVESLFDISWLYNNLVGVVVSLGVGYVVGLTAPAPSAAQ
LRDVVIEETAPDMQALLATRAARARSITPAARLTRRRCIGLVAWFCLLLAGLALLQGWANA

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI256985183, Length=454, Percent_Identity=33.0396475770925, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI157671931, Length=457, Percent_Identity=29.3216630196937, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI167466278, Length=447, Percent_Identity=30.8724832214765, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI4507035, Length=416, Percent_Identity=30.7692307692308, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI14140236, Length=467, Percent_Identity=25.0535331905782, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4507033, Length=469, Percent_Identity=27.9317697228145, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI17941285, Length=461, Percent_Identity=26.2472885032538, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI4507031, Length=460, Percent_Identity=26.5217391304348, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI206597483, Length=448, Percent_Identity=27.6785714285714, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI110835708, Length=557, Percent_Identity=25.1346499102334, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI109659836, Length=467, Percent_Identity=26.9807280513919, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI109659839, Length=483, Percent_Identity=26.0869565217391, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI206597487, Length=478, Percent_Identity=25.5230125523013, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1790113, Length=482, Percent_Identity=22.4066390041494, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082237, Length=463, Percent_Identity=25.4859611231102, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787251, Length=510, Percent_Identity=24.1176470588235, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790503, Length=460, Percent_Identity=24.1304347826087, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32566512, Length=382, Percent_Identity=27.2251308900524, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI115533094, Length=420, Percent_Identity=27.8571428571429, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI115533096, Length=312, Percent_Identity=28.8461538461538, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17539284, Length=473, Percent_Identity=24.5243128964059, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573698, Length=450, Percent_Identity=31.3333333333333, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24651739, Length=457, Percent_Identity=30.1969365426696, Blast_Score=206, Evalue=5e-53,
Organism=Drosophila melanogaster, GI281362918, Length=452, Percent_Identity=30.5309734513274, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24651741, Length=461, Percent_Identity=26.4642082429501, Blast_Score=185, Evalue=9e-47,
Organism=Drosophila melanogaster, GI24645928, Length=448, Percent_Identity=31.6964285714286, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI221459588, Length=468, Percent_Identity=29.2735042735043, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI221459586, Length=466, Percent_Identity=28.755364806867, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI221459584, Length=467, Percent_Identity=28.6937901498929, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24641117, Length=444, Percent_Identity=30.4054054054054, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI28574994, Length=442, Percent_Identity=26.4705882352941, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24640370, Length=479, Percent_Identity=27.348643006263, Blast_Score=155, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24650192, Length=448, Percent_Identity=27.0089285714286, Blast_Score=152, Evalue=7e-37,
Organism=Drosophila melanogaster, GI221459582, Length=452, Percent_Identity=27.6548672566372, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI19920916, Length=425, Percent_Identity=26.1176470588235, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI221379702, Length=414, Percent_Identity=26.0869565217391, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281362054, Length=364, Percent_Identity=28.8461538461538, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI281362052, Length=364, Percent_Identity=28.8461538461538, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI281362050, Length=364, Percent_Identity=28.8461538461538, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24648056, Length=364, Percent_Identity=28.8461538461538, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI21356827, Length=364, Percent_Identity=28.8461538461538, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI161076631, Length=415, Percent_Identity=26.0240963855422, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI281364280, Length=336, Percent_Identity=26.1904761904762, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58141; Mature: 58010

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFTWLDSVVLVVYILLVALIGARFGRSQQSTQDYFLGGRRIPGWAIGLSVMATQASAI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHE
TFIGAPGWGFEGGLERLVTFLNVPLAMAVLIFLLVPVFHRAGIYSIYELLERRFGPATRS
EEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHH
VSAGLFLVARGLATGVVLYAPALVLSVVTGWSVNLTIVVMAVLAVSYTVLGGISAVIWTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIQMFVLWLGALVSMGLMVASLPGGWSDVFAFGAAQGMFDTLDLSLDPGVTYSLWAGLFG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHH
GIFLHIAYFGTDQSQIQRVLTSPDVQQGQRSLLIGGYLLVPQMLLFLFIGVMLATYYDQH
HHHHHHHHHCCCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLAAPDNLNELFPRYVVSAFPPGLAGLVIAGVFAAAMSSLDSALNSLSAVSVRDFYTRYV
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPDASEAHYLKASRWATVFWGLYATVFAFFAGNLGPVIEAVNRIGSWFYGALLGTFLLAM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHRTNARGALSGLVLGMVSVWGVESLFDISWLYNNLVGVVVSLGVGYVVGLTAPAPSAA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHH
QLRDVVIEETAPDMQALLATRAARARSITPAARLTRRRCIGLVAWFCLLLAGLALLQGWA
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NA
CC
>Mature Secondary Structure 
SEFTWLDSVVLVVYILLVALIGARFGRSQQSTQDYFLGGRRIPGWAIGLSVMATQASAI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHE
TFIGAPGWGFEGGLERLVTFLNVPLAMAVLIFLLVPVFHRAGIYSIYELLERRFGPATRS
EEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHH
VSAGLFLVARGLATGVVLYAPALVLSVVTGWSVNLTIVVMAVLAVSYTVLGGISAVIWTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIQMFVLWLGALVSMGLMVASLPGGWSDVFAFGAAQGMFDTLDLSLDPGVTYSLWAGLFG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHH
GIFLHIAYFGTDQSQIQRVLTSPDVQQGQRSLLIGGYLLVPQMLLFLFIGVMLATYYDQH
HHHHHHHHHCCCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLAAPDNLNELFPRYVVSAFPPGLAGLVIAGVFAAAMSSLDSALNSLSAVSVRDFYTRYV
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPDASEAHYLKASRWATVFWGLYATVFAFFAGNLGPVIEAVNRIGSWFYGALLGTFLLAM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHRTNARGALSGLVLGMVSVWGVESLFDISWLYNNLVGVVVSLGVGYVVGLTAPAPSAA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHH
QLRDVVIEETAPDMQALLATRAARARSITPAARLTRRRCIGLVAWFCLLLAGLALLQGWA
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]