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The map label for this gene is leuE [H]

Identifier: 92112174

GI number: 92112174

Start: 46306

End: 46941

Strand: Direct

Name: leuE [H]

Synonym: Csal_0038

Alternate gene names: 92112174

Gene position: 46306-46941 (Clockwise)

Preceding gene: 92112173

Following gene: 92112183

Centisome position: 1.25

GC content: 60.22

Gene sequence:

>636_bases
ATGTTCGATTATTCGTTGGTGCATTGGCTGGCGTTCTTGTCAGCGGCGGTGCTTCTGAACCTTTCTCCAGGGCCGGATAT
CGCGTTCATGCTAGGCCAGACGCTACGCAGCGGGCGTCGACATGGGTTCGCTGCGATGCTCGGGGGTTGGTCGGGTACGG
CATTGCATGTGGCTATGGCGGCGGCGGGCCTGTCGGCCATTCTGGCCACCTCGGCGGTGGCGTTTTCGGTGATCAAGTGG
GTCGGGGCTGCCTATTTGATATGGCTCGGCGTCAAGATGCTGTTGTCCAAGGGGGATTCTTTTATTTCCAATGGCGGTGG
CCGGGACGCAAAGGCGCAGTCGGTCTATTGGCAGGGTGTGCTGGTGTCCGCGCTGAACCCTAAAGTGGCCGTCTTCTTTC
TCGCCTTCTTGCCGCAGTTCGTCGTGGCAGGTGCCGGGCCGGTGGGTGCCCAGCTGTTCTTGCATGGCAGCTTGATTATC
GTGGTCGCAGCTTTTATAGAGCCTCTTTTGGTGATGATGGGGGCGAAACTGGGCGCTTTCTTGAAGGCAAGCCCGCGAGT
GGGGATGTGGATGGATCGCGGCCTTGGTGCCATGTTCGTTGCCCTGGGGGCGCGTCTGGCCGCCAGCACCAGATAA

Upstream 100 bases:

>100_bases
ATATTGGAAATAATCGGTGTTGGCGCCGCGCGTGAGCGCGCGAATTTTGCGGTTGGCATCTACAACTCACTGATTCGACC
CATAATGGGATGATTGCGAT

Downstream 100 bases:

>100_bases
CATCAGGATGGCGGCGGGGTGTTCCATTGGCTACATGAATTCCCCACCCCCGACTCATTCCTTGGGACTGGAGTAGACGC
TCAGCGCGGTCACCGTGGCG

Product: lysine exporter protein LysE/YggA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFDYSLVHWLAFLSAAVLLNLSPGPDIAFMLGQTLRSGRRHGFAAMLGGWSGTALHVAMAAAGLSAILATSAVAFSVIKW
VGAAYLIWLGVKMLLSKGDSFISNGGGRDAKAQSVYWQGVLVSALNPKVAVFFLAFLPQFVVAGAGPVGAQLFLHGSLII
VVAAFIEPLLVMMGAKLGAFLKASPRVGMWMDRGLGAMFVALGARLAASTR

Sequences:

>Translated_211_residues
MFDYSLVHWLAFLSAAVLLNLSPGPDIAFMLGQTLRSGRRHGFAAMLGGWSGTALHVAMAAAGLSAILATSAVAFSVIKW
VGAAYLIWLGVKMLLSKGDSFISNGGGRDAKAQSVYWQGVLVSALNPKVAVFFLAFLPQFVVAGAGPVGAQLFLHGSLII
VVAAFIEPLLVMMGAKLGAFLKASPRVGMWMDRGLGAMFVALGARLAASTR
>Mature_211_residues
MFDYSLVHWLAFLSAAVLLNLSPGPDIAFMLGQTLRSGRRHGFAAMLGGWSGTALHVAMAAAGLSAILATSAVAFSVIKW
VGAAYLIWLGVKMLLSKGDSFISNGGGRDAKAQSVYWQGVLVSALNPKVAVFFLAFLPQFVVAGAGPVGAQLFLHGSLII
VVAAFIEPLLVMMGAKLGAFLKASPRVGMWMDRGLGAMFVALGARLAASTR

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=206, Percent_Identity=25.7281553398058, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI48994979, Length=214, Percent_Identity=28.5046728971963, Blast_Score=94, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22055; Mature: 22055

Theoretical pI: Translated: 11.16; Mature: 11.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDYSLVHWLAFLSAAVLLNLSPGPDIAFMLGQTLRSGRRHGFAAMLGGWSGTALHVAMA
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHH
AAGLSAILATSAVAFSVIKWVGAAYLIWLGVKMLLSKGDSFISNGGGRDAKAQSVYWQGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHH
LVSALNPKVAVFFLAFLPQFVVAGAGPVGAQLFLHGSLIIVVAAFIEPLLVMMGAKLGAF
HHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKASPRVGMWMDRGLGAMFVALGARLAASTR
HHCCCCCCHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFDYSLVHWLAFLSAAVLLNLSPGPDIAFMLGQTLRSGRRHGFAAMLGGWSGTALHVAMA
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHH
AAGLSAILATSAVAFSVIKWVGAAYLIWLGVKMLLSKGDSFISNGGGRDAKAQSVYWQGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHH
LVSALNPKVAVFFLAFLPQFVVAGAGPVGAQLFLHGSLIIVVAAFIEPLLVMMGAKLGAF
HHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKASPRVGMWMDRGLGAMFVALGARLAASTR
HHCCCCCCHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]