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The map label for this gene is lrp [H]

Identifier: 91790477

GI number: 91790477

Start: 4934201

End: 4934692

Strand: Direct

Name: lrp [H]

Synonym: Bpro_4648

Alternate gene names: 91790477

Gene position: 4934201-4934692 (Clockwise)

Preceding gene: 91790471

Following gene: 91790478

Centisome position: 94.88

GC content: 60.57

Gene sequence:

>492_bases
ATGGAACATTTAGACAAGTTTGACATTGCCATACTGAATGAGTTGCAGCGTGAGGCGCGTCTGACCAATACCGAACTCGC
GTCCCGCGTCGGCCTGTCGGCTGCACCCTGCTGGCGGCGCGTGCGGGCGCTGGAGGAAGCCGGGTTCATCACCGGCTATC
GAGCCGAGATCAACCGCCACAAGATCGGTTTGGGCGTGCTGGCCTTTGTCCGGCTGGACGCGGACCGCAACAGCGGGGAC
GCCACGCGGCAACTGGAAGAAGCCATCAAGAAACTGCCTGAAGTCATCGCCTGCCACTACATCAGCGGCACCGGAACCTT
CGAGCTGCAGGTGGTGGCCCAGGACCTTGAAGCTTTCAGCAAGTTTGCGCTGCAGAGCCTGATCAACCTGCCCAATGTGA
AAGACCTGCACACCAGTTTCTCGCTGGGGGAGGTCAAGGCCAGCAGTTCGCTGCCGCTGGGGCATCTGGCACGCACGGCA
CCTTCATCATAA

Upstream 100 bases:

>100_bases
AACTGTCTGCAAAGTGTAGGGCGGGCGGCCAGATATGTCTTTGCTTTCTTTGCCTGATTTAGGGTGTACAAAGAAAGGAT
CTTGCTGGAAAATACGATAA

Downstream 100 bases:

>100_bases
AAATACCCGTTAGCCCCTATATTGACCGGATCACAAGCTACTAATTTCATAGCAAAATATCCTGAACCGACACCTTCTCG
CGCCAACCCACCGCAGCGCT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MEHLDKFDIAILNELQREARLTNTELASRVGLSAAPCWRRVRALEEAGFITGYRAEINRHKIGLGVLAFVRLDADRNSGD
ATRQLEEAIKKLPEVIACHYISGTGTFELQVVAQDLEAFSKFALQSLINLPNVKDLHTSFSLGEVKASSSLPLGHLARTA
PSS

Sequences:

>Translated_163_residues
MEHLDKFDIAILNELQREARLTNTELASRVGLSAAPCWRRVRALEEAGFITGYRAEINRHKIGLGVLAFVRLDADRNSGD
ATRQLEEAIKKLPEVIACHYISGTGTFELQVVAQDLEAFSKFALQSLINLPNVKDLHTSFSLGEVKASSSLPLGHLARTA
PSS
>Mature_163_residues
MEHLDKFDIAILNELQREARLTNTELASRVGLSAAPCWRRVRALEEAGFITGYRAEINRHKIGLGVLAFVRLDADRNSGD
ATRQLEEAIKKLPEVIACHYISGTGTFELQVVAQDLEAFSKFALQSLINLPNVKDLHTSFSLGEVKASSSLPLGHLARTA
PSS

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=150, Percent_Identity=41.3333333333333, Blast_Score=126, Evalue=9e-31,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=30, Blast_Score=94, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17913; Mature: 17913

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHLDKFDIAILNELQREARLTNTELASRVGLSAAPCWRRVRALEEAGFITGYRAEINRH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
KIGLGVLAFVRLDADRNSGDATRQLEEAIKKLPEVIACHYISGTGTFELQVVAQDLEAFS
HHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHH
KFALQSLINLPNVKDLHTSFSLGEVKASSSLPLGHLARTAPSS
HHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure
MEHLDKFDIAILNELQREARLTNTELASRVGLSAAPCWRRVRALEEAGFITGYRAEINRH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
KIGLGVLAFVRLDADRNSGDATRQLEEAIKKLPEVIACHYISGTGTFELQVVAQDLEAFS
HHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHH
KFALQSLINLPNVKDLHTSFSLGEVKASSSLPLGHLARTAPSS
HHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]