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The map label for this gene is fmt [H]

Identifier: 91790467

GI number: 91790467

Start: 4919022

End: 4920095

Strand: Reverse

Name: fmt [H]

Synonym: Bpro_4638

Alternate gene names: 91790467

Gene position: 4920095-4919022 (Counterclockwise)

Preceding gene: 91790468

Following gene: 91790466

Centisome position: 94.61

GC content: 67.6

Gene sequence:

>1074_bases
ATGTTCCCGGCCGGGATCTGCCCGGGGGACCGTATTGCCGGGGCTTTGCAGGCGTCCCTCCGGGTTTTCCCCGGTGAGTC
TTTAGAATCCTGCTTCATGCGCGTCATTTTTGCCGGTACCCCTGAGTTTGCCCGCGTGGCACTGGCAAGTCTGCAGGCCG
CCGGTTTTGACATCCCGCTCGTGCTGACGCAGCCCGACCGGCCCGCCGGGCGCGGCATGAAGCTGCAGGCGTCAGCCGTG
AAGCAGTGGGCGCAGAGCCATCAGGTCCCGGTAGCGCAGCCCCGCAGCCTGCGGTTGGACGGCAAATACCCCGACGATGC
GGCGGCCGCCAGAACTGCCATCGAGGCGGCGCGCGCCGACGTGATGGTGGTCGCAGCCTACGGACTGATCCTGCCGCAAT
GGGTGCTTGATGCACCCCGGCTCGGCTGCCTGAATATCCACGCATCACTGCTGCCGCGCTGGCGCGGCGCCGCACCGATT
CACCGGGCCATCGAAGCCGGTGACGCACAGACCGGCGTCACCATCATGCAGATGGATGCCGGCCTCGACACGGGTGACAT
GCTGCTGCTGGAGAAGCTGACCATTGGCCCGGAGGACACGACGGCATCGCTGCACGACAGGCTGGCCGGGCTGGGTGGGC
GACTGATTGTGAACGCCCTGGAACTAGCCGCAGGCGGCGCGCTCCGGCCCCTTGTCCAGCCCTCCGAAGGCATCACATAC
GCCCACAAGATCGAAAAAAACGAGGCCCTGCTGGACTGGACCCGCAGCGCAGCCGCGCTGGAGCGCCGCATTCGCGCTTT
CAATCCTTTCCCCGGCGCCGCCGGTGTGCTGGACGGCGAAACCATCAAATTCTGGCGCGCGGCGGTGCCGGCCGGTGCGC
TGCGGCCGGTGGGCGTGCTGCCCGGCCAGGTGGTCGCCGCCGGCCCCGAGGGTATCGACATCTGCGCTGCCGATGCCCTG
GTGCGTGTGACCCGCCTGCAAAAAGCGGGCGGCAAGGCGCTGGAGGCGGCCGATTTTCTGCGCGGGTTCGAGATCCGTCC
CGGCATGGTGTTCAATCCCACTCAGACGGAATGA

Upstream 100 bases:

>100_bases
CCGCATCAAGACCAAGATGATCAAGCAGAAAAAAGACGAGGAGCGGGAGTCCGCCCGCTGACGCGCCACCGCGGTACCGC
CAAGGGGCCTTCCGCTGGTT

Downstream 100 bases:

>100_bases
GGTTTTTGTGAGTTCATTGTTCAAGCACCCGGAGTTTCGGGTGGGTGTGCGCGACCTGGCTCCAGTCGCGCCCGGTATTG
CCGCCTGGGGACTGATGACC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MFPAGICPGDRIAGALQASLRVFPGESLESCFMRVIFAGTPEFARVALASLQAAGFDIPLVLTQPDRPAGRGMKLQASAV
KQWAQSHQVPVAQPRSLRLDGKYPDDAAAARTAIEAARADVMVVAAYGLILPQWVLDAPRLGCLNIHASLLPRWRGAAPI
HRAIEAGDAQTGVTIMQMDAGLDTGDMLLLEKLTIGPEDTTASLHDRLAGLGGRLIVNALELAAGGALRPLVQPSEGITY
AHKIEKNEALLDWTRSAAALERRIRAFNPFPGAAGVLDGETIKFWRAAVPAGALRPVGVLPGQVVAAGPEGIDICAADAL
VRVTRLQKAGGKALEAADFLRGFEIRPGMVFNPTQTE

Sequences:

>Translated_357_residues
MFPAGICPGDRIAGALQASLRVFPGESLESCFMRVIFAGTPEFARVALASLQAAGFDIPLVLTQPDRPAGRGMKLQASAV
KQWAQSHQVPVAQPRSLRLDGKYPDDAAAARTAIEAARADVMVVAAYGLILPQWVLDAPRLGCLNIHASLLPRWRGAAPI
HRAIEAGDAQTGVTIMQMDAGLDTGDMLLLEKLTIGPEDTTASLHDRLAGLGGRLIVNALELAAGGALRPLVQPSEGITY
AHKIEKNEALLDWTRSAAALERRIRAFNPFPGAAGVLDGETIKFWRAAVPAGALRPVGVLPGQVVAAGPEGIDICAADAL
VRVTRLQKAGGKALEAADFLRGFEIRPGMVFNPTQTE
>Mature_357_residues
MFPAGICPGDRIAGALQASLRVFPGESLESCFMRVIFAGTPEFARVALASLQAAGFDIPLVLTQPDRPAGRGMKLQASAV
KQWAQSHQVPVAQPRSLRLDGKYPDDAAAARTAIEAARADVMVVAAYGLILPQWVLDAPRLGCLNIHASLLPRWRGAAPI
HRAIEAGDAQTGVTIMQMDAGLDTGDMLLLEKLTIGPEDTTASLHDRLAGLGGRLIVNALELAAGGALRPLVQPSEGITY
AHKIEKNEALLDWTRSAAALERRIRAFNPFPGAAGVLDGETIKFWRAAVPAGALRPVGVLPGQVVAAGPEGIDICAADAL
VRVTRLQKAGGKALEAADFLRGFEIRPGMVFNPTQTE

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=321, Percent_Identity=29.9065420560748, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI238814322, Length=337, Percent_Identity=27.5964391691395, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI164663775, Length=326, Percent_Identity=29.7546012269939, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789683, Length=309, Percent_Identity=49.1909385113269, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI1788589, Length=306, Percent_Identity=23.5294117647059, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI133930964, Length=323, Percent_Identity=28.4829721362229, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45550868, Length=314, Percent_Identity=28.9808917197452, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI28571984, Length=276, Percent_Identity=29.7101449275362, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24585660, Length=325, Percent_Identity=25.8461538461538, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 37718; Mature: 37718

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPAGICPGDRIAGALQASLRVFPGESLESCFMRVIFAGTPEFARVALASLQAAGFDIPL
CCCCCCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEE
VLTQPDRPAGRGMKLQASAVKQWAQSHQVPVAQPRSLRLDGKYPDDAAAARTAIEAARAD
EEECCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCC
VMVVAAYGLILPQWVLDAPRLGCLNIHASLLPRWRGAAPIHRAIEAGDAQTGVTIMQMDA
EEEEHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEEECC
GLDTGDMLLLEKLTIGPEDTTASLHDRLAGLGGRLIVNALELAAGGALRPLVQPSEGITY
CCCCCCCCEEHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEE
AHKIEKNEALLDWTRSAAALERRIRAFNPFPGAAGVLDGETIKFWRAAVPAGALRPVGVL
EEHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
PGQVVAAGPEGIDICAADALVRVTRLQKAGGKALEAADFLRGFEIRPGMVFNPTQTE
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCCC
>Mature Secondary Structure
MFPAGICPGDRIAGALQASLRVFPGESLESCFMRVIFAGTPEFARVALASLQAAGFDIPL
CCCCCCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEE
VLTQPDRPAGRGMKLQASAVKQWAQSHQVPVAQPRSLRLDGKYPDDAAAARTAIEAARAD
EEECCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCC
VMVVAAYGLILPQWVLDAPRLGCLNIHASLLPRWRGAAPIHRAIEAGDAQTGVTIMQMDA
EEEEHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEEECC
GLDTGDMLLLEKLTIGPEDTTASLHDRLAGLGGRLIVNALELAAGGALRPLVQPSEGITY
CCCCCCCCEEHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEE
AHKIEKNEALLDWTRSAAALERRIRAFNPFPGAAGVLDGETIKFWRAAVPAGALRPVGVL
EEHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
PGQVVAAGPEGIDICAADALVRVTRLQKAGGKALEAADFLRGFEIRPGMVFNPTQTE
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA