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The map label for this gene is pgk [H]

Identifier: 91790464

GI number: 91790464

Start: 4916420

End: 4917751

Strand: Reverse

Name: pgk [H]

Synonym: Bpro_4635

Alternate gene names: 91790464

Gene position: 4917751-4916420 (Counterclockwise)

Preceding gene: 91790465

Following gene: 91790463

Centisome position: 94.57

GC content: 65.99

Gene sequence:

>1332_bases
TTGCCAGACCGCAGGCGCCGCCCCCTGAGGGGGGAACAGGCTACACGAAGTGAGACTGGACGGGGGTGGGCCTATACACC
GACCTACAATTTAAGGCTTCGGCCGTGTTGGCCAGCTTATTTCACTTGCGAGCGATCCATGAATTTCATCCGTTTTTCCG
ACCTGTGTGCCAGCGGCAAGGCCGCCGGCCAGCGCGTTTTCATCCGTGCCGACCTGAACGTGCCGCAGGATGACAGCGGC
GCCATCACCGAAGACACGCGCATACGTGCCTCCATTCCCTGCCTGCAAATGGCGCTGGACGCGGGTGCGGCCGTGATGGT
GACCTCCCACCTCGGGCGTCCGGTGGAGGGCGAATTCAAGCCGGCCGACTCGCTGGCCCCGGTGGCCAAACGCCTGGGCG
AGCTGATGAAGCGCGAGATTCCGCTGGTCACCCAGTGGGTGGACGGCGTGGACGTCCAGCCCGGGCAGCTGGTGTTGCTG
GAGAACTGCCGCCTCAACCCCGGCGAGAAGAAAAACAGCGAAGCGCTGGCCCGCAAGATGGCCGCCCTGTGCGACATCTT
TGTGCACGACGCGTTTGGCACCGCCCACCGCGCCGAGGCCTCGACCTATGGCATTGCGCAATACGCCAAGGTAGCGAGCG
CCGGGCCGCTGCTGGCCGCCGAGATGGACGCGATTTCGACGGCGCTGTCCAACCCGCGCAGGCCGCTGGTCGCGATCGTC
GCGGGCAGCAAGGTCTCGACCAAGCTGACCATCCTCAAGTCCCTGGCCAGCAATGTGGACCAGCTGATCGTGGGCGGCGG
CATCGCCAACACCTTCATGCTGGCGGCCGGCCTGAAGATTGGCAAAAGCCTGGCGGAGGCCGACCTGCTGCCCGAGGCCC
GTGCCGTGATCGAGGCCATGAAGGCACGCGGCGCTGCGGTGCCCATCCCCACCGACGTGGTCACGGCCAAGACCTTCGCG
GCCGATGCCACGGCCACCGTCAAGGCCGCCACCGACGTGGAAGACGACGACCTGATCCTGGACATCGGCCCCGAGACCAC
GGCCCGGTTGGCGGCGCAGCTCAAGGCGGCTGGCACCATTGTCTGGAATGGCCCGGTGGGCGTGTTCGAGTTTGATGCTT
TTTCGCGCGGTACCGAAGGCATTGCCCGGGCGATCGCCGACAGCAGCGCCTTTTCGATTGCCGGTGGTGGCGACACGCTG
GCTGCCATCGCCAAATACGGCATCGAGAAACAGGTGGGCTACATCTCCACGGGGGGCGGCGCATTCCTGGAGGTGCTGGA
AGGCAAGACGCTGCCAGCCTTCGAAATCCTGCAGAAGCGGGCCGCCGGCTAG

Upstream 100 bases:

>100_bases
CCGGCCCGGCAAAGCCGGTTCCGGGGCTCATGCTTGGTTGAAGAGTCCCTAACTTCAGCCGTCGCCCGATTTCACGCCAG
CAGGGGCCGCGGGACTGGCT

Downstream 100 bases:

>100_bases
AGTCTTTGCGCTCCTGATTTGGTAGCGATAAGCCAAGGTTTAATGGGCGCCATCGATCTTTTCTTCCCAAAAAAGGGTGC
TTCGGCACCCTTTTTTCTGC

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MPDRRRRPLRGEQATRSETGRGWAYTPTYNLRLRPCWPAYFTCERSMNFIRFSDLCASGKAAGQRVFIRADLNVPQDDSG
AITEDTRIRASIPCLQMALDAGAAVMVTSHLGRPVEGEFKPADSLAPVAKRLGELMKREIPLVTQWVDGVDVQPGQLVLL
ENCRLNPGEKKNSEALARKMAALCDIFVHDAFGTAHRAEASTYGIAQYAKVASAGPLLAAEMDAISTALSNPRRPLVAIV
AGSKVSTKLTILKSLASNVDQLIVGGGIANTFMLAAGLKIGKSLAEADLLPEARAVIEAMKARGAAVPIPTDVVTAKTFA
ADATATVKAATDVEDDDLILDIGPETTARLAAQLKAAGTIVWNGPVGVFEFDAFSRGTEGIARAIADSSAFSIAGGGDTL
AAIAKYGIEKQVGYISTGGGAFLEVLEGKTLPAFEILQKRAAG

Sequences:

>Translated_443_residues
MPDRRRRPLRGEQATRSETGRGWAYTPTYNLRLRPCWPAYFTCERSMNFIRFSDLCASGKAAGQRVFIRADLNVPQDDSG
AITEDTRIRASIPCLQMALDAGAAVMVTSHLGRPVEGEFKPADSLAPVAKRLGELMKREIPLVTQWVDGVDVQPGQLVLL
ENCRLNPGEKKNSEALARKMAALCDIFVHDAFGTAHRAEASTYGIAQYAKVASAGPLLAAEMDAISTALSNPRRPLVAIV
AGSKVSTKLTILKSLASNVDQLIVGGGIANTFMLAAGLKIGKSLAEADLLPEARAVIEAMKARGAAVPIPTDVVTAKTFA
ADATATVKAATDVEDDDLILDIGPETTARLAAQLKAAGTIVWNGPVGVFEFDAFSRGTEGIARAIADSSAFSIAGGGDTL
AAIAKYGIEKQVGYISTGGGAFLEVLEGKTLPAFEILQKRAAG
>Mature_442_residues
PDRRRRPLRGEQATRSETGRGWAYTPTYNLRLRPCWPAYFTCERSMNFIRFSDLCASGKAAGQRVFIRADLNVPQDDSGA
ITEDTRIRASIPCLQMALDAGAAVMVTSHLGRPVEGEFKPADSLAPVAKRLGELMKREIPLVTQWVDGVDVQPGQLVLLE
NCRLNPGEKKNSEALARKMAALCDIFVHDAFGTAHRAEASTYGIAQYAKVASAGPLLAAEMDAISTALSNPRRPLVAIVA
GSKVSTKLTILKSLASNVDQLIVGGGIANTFMLAAGLKIGKSLAEADLLPEARAVIEAMKARGAAVPIPTDVVTAKTFAA
DATATVKAATDVEDDDLILDIGPETTARLAAQLKAAGTIVWNGPVGVFEFDAFSRGTEGIARAIADSSAFSIAGGGDTLA
AIAKYGIEKQVGYISTGGGAFLEVLEGKTLPAFEILQKRAAG

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI31543397, Length=405, Percent_Identity=38.0246913580247, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI4505763, Length=403, Percent_Identity=35.7320099255583, Blast_Score=238, Evalue=7e-63,
Organism=Escherichia coli, GI1789294, Length=395, Percent_Identity=58.7341772151899, Blast_Score=446, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17508823, Length=404, Percent_Identity=42.8217821782178, Blast_Score=286, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6319857, Length=407, Percent_Identity=38.5749385749386, Blast_Score=244, Evalue=2e-65,
Organism=Drosophila melanogaster, GI17136394, Length=401, Percent_Identity=38.1546134663342, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24581203, Length=399, Percent_Identity=36.8421052631579, Blast_Score=222, Evalue=3e-58,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 46785; Mature: 46654

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDRRRRPLRGEQATRSETGRGWAYTPTYNLRLRPCWPAYFTCERSMNFIRFSDLCASGK
CCCCCCCCCCCCCHHHCCCCCCEEECCEECEEEEECCCHHHHHCCCCCEEEHHHHHCCCC
AAGQRVFIRADLNVPQDDSGAITEDTRIRASIPCLQMALDAGAAVMVTSHLGRPVEGEFK
CCCCEEEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCEEEEEHHCCCCCCCCCC
PADSLAPVAKRLGELMKREIPLVTQWVDGVDVQPGQLVLLENCRLNPGEKKNSEALARKM
CCCHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
AALCDIFVHDAFGTAHRAEASTYGIAQYAKVASAGPLLAAEMDAISTALSNPRRPLVAIV
HHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEE
AGSKVSTKLTILKSLASNVDQLIVGGGIANTFMLAAGLKIGKSLAEADLLPEARAVIEAM
ECCCCHHHHHHHHHHHHCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KARGAAVPIPTDVVTAKTFAADATATVKAATDVEDDDLILDIGPETTARLAAQLKAAGTI
HHCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHCCEE
VWNGPVGVFEFDAFSRGTEGIARAIADSSAFSIAGGGDTLAAIAKYGIEKQVGYISTGGG
EECCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCHHCCCEEECCCH
AFLEVLEGKTLPAFEILQKRAAG
HHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
PDRRRRPLRGEQATRSETGRGWAYTPTYNLRLRPCWPAYFTCERSMNFIRFSDLCASGK
CCCCCCCCCCCCHHHCCCCCCEEECCEECEEEEECCCHHHHHCCCCCEEEHHHHHCCCC
AAGQRVFIRADLNVPQDDSGAITEDTRIRASIPCLQMALDAGAAVMVTSHLGRPVEGEFK
CCCCEEEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCEEEEEHHCCCCCCCCCC
PADSLAPVAKRLGELMKREIPLVTQWVDGVDVQPGQLVLLENCRLNPGEKKNSEALARKM
CCCHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
AALCDIFVHDAFGTAHRAEASTYGIAQYAKVASAGPLLAAEMDAISTALSNPRRPLVAIV
HHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEE
AGSKVSTKLTILKSLASNVDQLIVGGGIANTFMLAAGLKIGKSLAEADLLPEARAVIEAM
ECCCCHHHHHHHHHHHHCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KARGAAVPIPTDVVTAKTFAADATATVKAATDVEDDDLILDIGPETTARLAAQLKAAGTI
HHCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHCCEE
VWNGPVGVFEFDAFSRGTEGIARAIADSSAFSIAGGGDTLAAIAKYGIEKQVGYISTGGG
EECCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCHHCCCEEECCCH
AFLEVLEGKTLPAFEILQKRAAG
HHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA