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The map label for this gene is aaeR [H]

Identifier: 91790409

GI number: 91790409

Start: 4850311

End: 4851258

Strand: Reverse

Name: aaeR [H]

Synonym: Bpro_4580

Alternate gene names: 91790409

Gene position: 4851258-4850311 (Counterclockwise)

Preceding gene: 91790411

Following gene: 91790408

Centisome position: 93.29

GC content: 72.26

Gene sequence:

>948_bases
ATGGATCAACTCAAGCGCATGGCCATCTTTGCCGAAGTCGTGGCGGCAGGCTCCCTGACTGCGGCGGCGCGGCAACTGGG
CATGACGCCCTCGGCGGTGAGCCAGCATTTGCGCCAGCTGGAACAGGCGCTGGGGCTGGCGCTGCTGCACCGCTCCACCC
GGCGGCTCACCCTGACCGAGGCGGGCGAGCGCTACCACGCAGGCTGCGCCGCGATGGTGGCGGCGGCGCGCTCGGCCGAG
CAGGCCCTGGCGCGCCTGCGCGATGAGCCCGAAGGCGAATTGCGGCTGGCCGCGCCCGCCGGCTTTGGCAGCGTCCTGGC
CACCGCGCTGGCGCCGCTGCGGGGCTACCCCAGGCTCACGCTGCGCCTGCTGCTCGATGACGCACTGATTGACCTGATCG
GGGAGCGCGTGGATATCGCGCTTCGCATTGGCGTGCTGGCCGATTCAGGCCTGGTGGCGCGCAAGCTGGGCAGCATGGCG
CGCCAGCTGTGTGCGTCGCCGGCCTACCTGGCCGAGCGCGGCTGGCCTGCGCAGCCGCGTGATCTGCTGCAGCATGACTG
GCTCGGCAGCAAACCGGCCAACGCCGGCGCCGACATGCTGGAGCTGCAAGGACCTGCCGGCGAACGCGAGACGCTGCGGC
TCGAGGGCCGGGTGCAGGCTTCCCAGGTGACGGCCCTGCACGCGTTGTGTGTGGCGGGCTGGGGCATCAGCCTGGGCGTG
AGCGACGACGACCAGAAAGCGCTGGCGGACGGGCGCCTGTTGCCGGTGCTGCCCGGCTGGCGTCTGGCTGACTTGCCGGT
GTATGCGGTGACCCCGCGGCGCGGTGAGCAGCCGGCCAAGGTGCGCCATGCGCTGGACGTGCTGGCACTGTACTTCGGCG
ACGCGGGCGACGCGGGCGACGCGGGCGGCGCGGCTGCGGCGCACACTGCCACTGCCTTTCACTCCTGA

Upstream 100 bases:

>100_bases
AAGTAGAAGAGGCTCCAGTTTGATTGCTTCACAAGTTGCTGAATAGATGGCTTAATTGGCTAACACTGTGAAGTACAGCT
AACTAATGGGCCTCTAAACC

Downstream 100 bases:

>100_bases
CGAATTGCTTCGGCATGACGCAGCTCCCGCCGCTGTTGCCGATGCCGCAATGTCGTCTTTCCGGGCTGCGGCCGGTGTCG
GATTTACAGGCGGCCCTGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MDQLKRMAIFAEVVAAGSLTAAARQLGMTPSAVSQHLRQLEQALGLALLHRSTRRLTLTEAGERYHAGCAAMVAAARSAE
QALARLRDEPEGELRLAAPAGFGSVLATALAPLRGYPRLTLRLLLDDALIDLIGERVDIALRIGVLADSGLVARKLGSMA
RQLCASPAYLAERGWPAQPRDLLQHDWLGSKPANAGADMLELQGPAGERETLRLEGRVQASQVTALHALCVAGWGISLGV
SDDDQKALADGRLLPVLPGWRLADLPVYAVTPRRGEQPAKVRHALDVLALYFGDAGDAGDAGGAAAAHTATAFHS

Sequences:

>Translated_315_residues
MDQLKRMAIFAEVVAAGSLTAAARQLGMTPSAVSQHLRQLEQALGLALLHRSTRRLTLTEAGERYHAGCAAMVAAARSAE
QALARLRDEPEGELRLAAPAGFGSVLATALAPLRGYPRLTLRLLLDDALIDLIGERVDIALRIGVLADSGLVARKLGSMA
RQLCASPAYLAERGWPAQPRDLLQHDWLGSKPANAGADMLELQGPAGERETLRLEGRVQASQVTALHALCVAGWGISLGV
SDDDQKALADGRLLPVLPGWRLADLPVYAVTPRRGEQPAKVRHALDVLALYFGDAGDAGDAGGAAAAHTATAFHS
>Mature_315_residues
MDQLKRMAIFAEVVAAGSLTAAARQLGMTPSAVSQHLRQLEQALGLALLHRSTRRLTLTEAGERYHAGCAAMVAAARSAE
QALARLRDEPEGELRLAAPAGFGSVLATALAPLRGYPRLTLRLLLDDALIDLIGERVDIALRIGVLADSGLVARKLGSMA
RQLCASPAYLAERGWPAQPRDLLQHDWLGSKPANAGADMLELQGPAGERETLRLEGRVQASQVTALHALCVAGWGISLGV
SDDDQKALADGRLLPVLPGWRLADLPVYAVTPRRGEQPAKVRHALDVLALYFGDAGDAGDAGGAAAAHTATAFHS

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=300, Percent_Identity=36.3333333333333, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=33.7883959044369, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=34.1379310344828, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1789440, Length=258, Percent_Identity=31.0077519379845, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=29.4915254237288, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787589, Length=289, Percent_Identity=29.0657439446367, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=25.8620689655172, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33224; Mature: 33224

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50931 HTH_LYSR ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLKRMAIFAEVVAAGSLTAAARQLGMTPSAVSQHLRQLEQALGLALLHRSTRRLTLTE
CCHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
AGERYHAGCAAMVAAARSAEQALARLRDEPEGELRLAAPAGFGSVLATALAPLRGYPRLT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHH
LRLLLDDALIDLIGERVDIALRIGVLADSGLVARKLGSMARQLCASPAYLAERGWPAQPR
HHHHHHHHHHHHHCCHHEEEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHH
DLLQHDWLGSKPANAGADMLELQGPAGERETLRLEGRVQASQVTALHALCVAGWGISLGV
HHHHHCCCCCCCCCCCCCCEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEECC
SDDDQKALADGRLLPVLPGWRLADLPVYAVTPRRGEQPAKVRHALDVLALYFGDAGDAGD
CCCHHHHHHCCCEEECCCCCEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
AGGAAAAHTATAFHS
CCCCHHHHHHHHCCC
>Mature Secondary Structure
MDQLKRMAIFAEVVAAGSLTAAARQLGMTPSAVSQHLRQLEQALGLALLHRSTRRLTLTE
CCHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
AGERYHAGCAAMVAAARSAEQALARLRDEPEGELRLAAPAGFGSVLATALAPLRGYPRLT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHH
LRLLLDDALIDLIGERVDIALRIGVLADSGLVARKLGSMARQLCASPAYLAERGWPAQPR
HHHHHHHHHHHHHCCHHEEEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHH
DLLQHDWLGSKPANAGADMLELQGPAGERETLRLEGRVQASQVTALHALCVAGWGISLGV
HHHHHCCCCCCCCCCCCCCEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEECC
SDDDQKALADGRLLPVLPGWRLADLPVYAVTPRRGEQPAKVRHALDVLALYFGDAGDAGD
CCCHHHHHHCCCEEECCCCCEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
AGGAAAAHTATAFHS
CCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]