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The map label for this gene is glcB [H]

Identifier: 91790349

GI number: 91790349

Start: 4773023

End: 4775236

Strand: Direct

Name: glcB [H]

Synonym: Bpro_4517

Alternate gene names: 91790349

Gene position: 4773023-4775236 (Clockwise)

Preceding gene: 91790348

Following gene: 91790351

Centisome position: 91.78

GC content: 65.22

Gene sequence:

>2214_bases
ATGACCACCACGACCACTGAACGCACGCCCGCCCACCGCCTCCAGGTGGCCACCGGCCTCTACCGCTTTATTGAAGACAA
GGTGCTGCCCGGCACCGGCGTTGACAGCGCGGCCTTCTGGCAGGGCTTTGACGCCATCGTGGCCGACCTGGCGCCCAAAA
ACATTGCCTTGCTGGCCGAGCGCGATCGCCTGCAAAGCGAGATCGACAGCTGGCATCAGGCCCATCCCGGCCCCATCACC
GACATGCCGGCCTACCGCGCCTTTCTGGAACAGATCGGCTACCTGGTGGCGCAGCCCGCCAACGTGACCACCACCACCGC
TGATGTCGACGCCGAACTGGCCGAGCAGGCCGGCCCGCAACTCGTGGTGCCCATCCTGAATGCCCGCTACGCGCTGAACG
CGGCCAATGCCCGCTGGGGCTCGCTCTATGACGCGCTGTATGGCACGGACGCCATCTCCGAATCCGGCGGCGCCGAGAAG
GGCAAGGCCTACAACCCGCTACGCGGCGCCAGGGTGATCGAGTTCGCGCGCACCTTCCTCGACCAGGCCGCCCCGCTGGA
GGCTGTGTCGCACAAGGAGTCGGCGGGCTACACCGTCGTGGACGGCAAGCTGGTTGTGACGCTGACGAACGGCGGCCGCA
GCAGCCTGCAGGACAACACCCAGCTCATCGGCTACCAGGGCGACGCTGGCGCCCCCTCGTCGGTGCTGCTCAAGCACAAC
GGCATCCACATTGACATCCAGATCGACCGCAGCACACCGATTGGCCAGAGCGATGCGGCCGGCGTCAGCGACCTGGTGCT
GGAGTCCGCGCTGTCCACCATCCTGGACCTGGAAGACTCGGTCGCCGTGGTGGATGCCGAAGACAAGGTGCTGGCCTACA
GCAACTGGCTGGGCATCCTGCAGGGCACGCTGACCGAAGAAGTCAGCAAGGGCGGCAAGACCTTCACGCGCGGCCTGAAC
CCGGACCGCCGATACACCGGCGCGCAGGGCGGTGAAGTCACGCTGCACGGCCGCTCGCTGATGTTTGTGCGCAATGTTGG
CCACCTGATGACCAACCCGGCCATCCTGTATGAAGGCGGCAGGGAAATTCCCGAGGGCATCATGGACGCGGTCATCACCA
CGACCATTGCCATGCACGACCTCAAGCGCAAAGGCCAGCCCGGCATCAGGAACTCGCGCGCCGGCTCGGTCTACATCGTC
AAGCCCAAGATGCATGGCCCCCAGGAGGTCGCGTTTGCATCCGAGCTGTTCAGCCGCGTCGAGGCACTGCTGGGCCTGCC
CGAGAACACCGTGAAGCTCGGCATCATGGACGAAGAGCGCCGCACCAGTGTCAACCTGAAGGCCTGCATTGCCGCGGCCG
GCGCCCGCGTGGCTTTCATCAACACCGGCTTCCTGGACCGCACCGGCGACGAGATGCACACCGCCATGCTGGCTGGCCCC
ATGATCCGCAAGGGCGATATGAAGACCAGCGCCTGGATTGGCGCCTATGAAAAGAACAACGTGCTGGTGGGCCTGTCCTG
CGGCCTGCGCGGCAAGGCGCAGATCGGCAAGGGCATGTGGGCCATGCCCGACCTGATGGCCGCCATGCTGGAGCAAAAGA
TTGCGCACCCCCGCGCCGGCGCCAACACCGCCTGGGTGCCCTCACCGACTGCCGCCACCCTGCACGCGCTGCACTACCAC
CAGGTGCTGGTGTCGGATGTGCAGAAGGAACTCGAGAAGATCGATGCCAATGCGGAACGCGACAACATCCTGAATGGCCT
GCTGCAAATTCCGGTGGTCGCCGAAGCCAGGTGGCCGGCGACGGAAAAGCAGCAGGAGCTGGACAACAATGCACAGGGCA
TCCTGGGCTACGTGGTGCGCTGGATCGACCAGGGCGTGGGCTGCTCCAAGGTGCCCGACATCCACAACGTCGCGCTGATG
GAAGACCGCGCCACGCTGCGCATTTCGAGCCAGCACATCGCCAACTGGCTGCACCATGGCGTGGTGACGAAGGATCAAGT
CATCGAAACCTTCCAGCGCATGGCCGCCGTGGTCGACAAGCAGAACGCCAGCGACCCGCTCTACCAAAACATGGCGGGCC
ACTTCGACACCTCAGCGGCTTACAAGGCCGCCTGCGACCTGGTGTTCAAGGGGCTGGAACAGCCGAGTGGCTACACCGAG
CCGCTGCTGCATGCCTGGCGGTTGAAAGTCAAGGCGGGTACGGCTTCGGCTTGA

Upstream 100 bases:

>100_bases
CGACGTGCTGACACTGCCGGGCATGAACCTGCCTGGCGCTGCGGCATGACACCGCCTTCATACCCTCCAACGTTTTATTT
TTTACAAGGGACGACCCACC

Downstream 100 bases:

>100_bases
CGACGCCATCTTCCCGATAGCGATAGCTAACGGCGAGTTGGGGCGAGTTGGCCGTTGATCATTTCGCCAGCTTGCGGTAG
AGCGTTGCGCGACCGATATT

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 737; Mature: 736

Protein sequence:

>737_residues
MTTTTTERTPAHRLQVATGLYRFIEDKVLPGTGVDSAAFWQGFDAIVADLAPKNIALLAERDRLQSEIDSWHQAHPGPIT
DMPAYRAFLEQIGYLVAQPANVTTTTADVDAELAEQAGPQLVVPILNARYALNAANARWGSLYDALYGTDAISESGGAEK
GKAYNPLRGARVIEFARTFLDQAAPLEAVSHKESAGYTVVDGKLVVTLTNGGRSSLQDNTQLIGYQGDAGAPSSVLLKHN
GIHIDIQIDRSTPIGQSDAAGVSDLVLESALSTILDLEDSVAVVDAEDKVLAYSNWLGILQGTLTEEVSKGGKTFTRGLN
PDRRYTGAQGGEVTLHGRSLMFVRNVGHLMTNPAILYEGGREIPEGIMDAVITTTIAMHDLKRKGQPGIRNSRAGSVYIV
KPKMHGPQEVAFASELFSRVEALLGLPENTVKLGIMDEERRTSVNLKACIAAAGARVAFINTGFLDRTGDEMHTAMLAGP
MIRKGDMKTSAWIGAYEKNNVLVGLSCGLRGKAQIGKGMWAMPDLMAAMLEQKIAHPRAGANTAWVPSPTAATLHALHYH
QVLVSDVQKELEKIDANAERDNILNGLLQIPVVAEARWPATEKQQELDNNAQGILGYVVRWIDQGVGCSKVPDIHNVALM
EDRATLRISSQHIANWLHHGVVTKDQVIETFQRMAAVVDKQNASDPLYQNMAGHFDTSAAYKAACDLVFKGLEQPSGYTE
PLLHAWRLKVKAGTASA

Sequences:

>Translated_737_residues
MTTTTTERTPAHRLQVATGLYRFIEDKVLPGTGVDSAAFWQGFDAIVADLAPKNIALLAERDRLQSEIDSWHQAHPGPIT
DMPAYRAFLEQIGYLVAQPANVTTTTADVDAELAEQAGPQLVVPILNARYALNAANARWGSLYDALYGTDAISESGGAEK
GKAYNPLRGARVIEFARTFLDQAAPLEAVSHKESAGYTVVDGKLVVTLTNGGRSSLQDNTQLIGYQGDAGAPSSVLLKHN
GIHIDIQIDRSTPIGQSDAAGVSDLVLESALSTILDLEDSVAVVDAEDKVLAYSNWLGILQGTLTEEVSKGGKTFTRGLN
PDRRYTGAQGGEVTLHGRSLMFVRNVGHLMTNPAILYEGGREIPEGIMDAVITTTIAMHDLKRKGQPGIRNSRAGSVYIV
KPKMHGPQEVAFASELFSRVEALLGLPENTVKLGIMDEERRTSVNLKACIAAAGARVAFINTGFLDRTGDEMHTAMLAGP
MIRKGDMKTSAWIGAYEKNNVLVGLSCGLRGKAQIGKGMWAMPDLMAAMLEQKIAHPRAGANTAWVPSPTAATLHALHYH
QVLVSDVQKELEKIDANAERDNILNGLLQIPVVAEARWPATEKQQELDNNAQGILGYVVRWIDQGVGCSKVPDIHNVALM
EDRATLRISSQHIANWLHHGVVTKDQVIETFQRMAAVVDKQNASDPLYQNMAGHFDTSAAYKAACDLVFKGLEQPSGYTE
PLLHAWRLKVKAGTASA
>Mature_736_residues
TTTTTERTPAHRLQVATGLYRFIEDKVLPGTGVDSAAFWQGFDAIVADLAPKNIALLAERDRLQSEIDSWHQAHPGPITD
MPAYRAFLEQIGYLVAQPANVTTTTADVDAELAEQAGPQLVVPILNARYALNAANARWGSLYDALYGTDAISESGGAEKG
KAYNPLRGARVIEFARTFLDQAAPLEAVSHKESAGYTVVDGKLVVTLTNGGRSSLQDNTQLIGYQGDAGAPSSVLLKHNG
IHIDIQIDRSTPIGQSDAAGVSDLVLESALSTILDLEDSVAVVDAEDKVLAYSNWLGILQGTLTEEVSKGGKTFTRGLNP
DRRYTGAQGGEVTLHGRSLMFVRNVGHLMTNPAILYEGGREIPEGIMDAVITTTIAMHDLKRKGQPGIRNSRAGSVYIVK
PKMHGPQEVAFASELFSRVEALLGLPENTVKLGIMDEERRTSVNLKACIAAAGARVAFINTGFLDRTGDEMHTAMLAGPM
IRKGDMKTSAWIGAYEKNNVLVGLSCGLRGKAQIGKGMWAMPDLMAAMLEQKIAHPRAGANTAWVPSPTAATLHALHYHQ
VLVSDVQKELEKIDANAERDNILNGLLQIPVVAEARWPATEKQQELDNNAQGILGYVVRWIDQGVGCSKVPDIHNVALME
DRATLRISSQHIANWLHHGVVTKDQVIETFQRMAAVVDKQNASDPLYQNMAGHFDTSAAYKAACDLVFKGLEQPSGYTEP
LLHAWRLKVKAGTASA

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=731, Percent_Identity=61.9699042407661, Blast_Score=962, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 79596; Mature: 79465

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTTTERTPAHRLQVATGLYRFIEDKVLPGTGVDSAAFWQGFDAIVADLAPKNIALLAE
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEH
RDRLQSEIDSWHQAHPGPITDMPAYRAFLEQIGYLVAQPANVTTTTADVDAELAEQAGPQ
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHCCCE
LVVPILNARYALNAANARWGSLYDALYGTDAISESGGAEKGKAYNPLRGARVIEFARTFL
EEEEECCCCEEEECCCCCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DQAAPLEAVSHKESAGYTVVDGKLVVTLTNGGRSSLQDNTQLIGYQGDAGAPSSVLLKHN
HHCCCHHHHCCCCCCCEEEECCEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEEEEC
GIHIDIQIDRSTPIGQSDAAGVSDLVLESALSTILDLEDSVAVVDAEDKVLAYSNWLGIL
CEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHH
QGTLTEEVSKGGKTFTRGLNPDRRYTGAQGGEVTLHGRSLMFVRNVGHLMTNPAILYEGG
HHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCEEEEECCEEEEHHHHHHHHCCCEEEECCC
REIPEGIMDAVITTTIAMHDLKRKGQPGIRNSRAGSVYIVKPKMHGPQEVAFASELFSRV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
EALLGLPENTVKLGIMDEERRTSVNLKACIAAAGARVAFINTGFLDRTGDEMHTAMLAGP
HHHHCCCCCCEEEEEECCHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCC
MIRKGDMKTSAWIGAYEKNNVLVGLSCGLRGKAQIGKGMWAMPDLMAAMLEQKIAHPRAG
CCCCCCCCCHHEEEEEECCCEEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCC
ANTAWVPSPTAATLHALHYHQVLVSDVQKELEKIDANAERDNILNGLLQIPVVAEARWPA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCC
TEKQQELDNNAQGILGYVVRWIDQGVGCSKVPDIHNVALMEDRATLRISSQHIANWLHHG
CHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEEEECHHHHHHHHHHC
VVTKDQVIETFQRMAAVVDKQNASDPLYQNMAGHFDTSAAYKAACDLVFKGLEQPSGYTE
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
PLLHAWRLKVKAGTASA
HHHHHHEEEEECCCCCC
>Mature Secondary Structure 
TTTTTERTPAHRLQVATGLYRFIEDKVLPGTGVDSAAFWQGFDAIVADLAPKNIALLAE
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEH
RDRLQSEIDSWHQAHPGPITDMPAYRAFLEQIGYLVAQPANVTTTTADVDAELAEQAGPQ
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHCCCE
LVVPILNARYALNAANARWGSLYDALYGTDAISESGGAEKGKAYNPLRGARVIEFARTFL
EEEEECCCCEEEECCCCCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DQAAPLEAVSHKESAGYTVVDGKLVVTLTNGGRSSLQDNTQLIGYQGDAGAPSSVLLKHN
HHCCCHHHHCCCCCCCEEEECCEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEEEEC
GIHIDIQIDRSTPIGQSDAAGVSDLVLESALSTILDLEDSVAVVDAEDKVLAYSNWLGIL
CEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHH
QGTLTEEVSKGGKTFTRGLNPDRRYTGAQGGEVTLHGRSLMFVRNVGHLMTNPAILYEGG
HHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCEEEEECCEEEEHHHHHHHHCCCEEEECCC
REIPEGIMDAVITTTIAMHDLKRKGQPGIRNSRAGSVYIVKPKMHGPQEVAFASELFSRV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
EALLGLPENTVKLGIMDEERRTSVNLKACIAAAGARVAFINTGFLDRTGDEMHTAMLAGP
HHHHCCCCCCEEEEEECCHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCC
MIRKGDMKTSAWIGAYEKNNVLVGLSCGLRGKAQIGKGMWAMPDLMAAMLEQKIAHPRAG
CCCCCCCCCHHEEEEEECCCEEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCC
ANTAWVPSPTAATLHALHYHQVLVSDVQKELEKIDANAERDNILNGLLQIPVVAEARWPA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCC
TEKQQELDNNAQGILGYVVRWIDQGVGCSKVPDIHNVALMEDRATLRISSQHIANWLHHG
CHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEEEECHHHHHHHHHHC
VVTKDQVIETFQRMAAVVDKQNASDPLYQNMAGHFDTSAAYKAACDLVFKGLEQPSGYTE
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
PLLHAWRLKVKAGTASA
HHHHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA