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The map label for this gene is ung [H]

Identifier: 91790283

GI number: 91790283

Start: 4704458

End: 4705207

Strand: Reverse

Name: ung [H]

Synonym: Bpro_4450

Alternate gene names: 91790283

Gene position: 4705207-4704458 (Counterclockwise)

Preceding gene: 91790284

Following gene: 91790282

Centisome position: 90.48

GC content: 69.6

Gene sequence:

>750_bases
ATGACGGACCTGTTTCTGGATGAGGCGTCGGCGCTGGGCGTCGCGGACCGCCTGACCAGCGCGGACCCCTTGGCCTGGCC
GGTAGCGCCCGGGTGGGAGCCTGTCACCAAGGCGTTTTTTTCCAGCGCGACCGGCCAGAAGCTGCTGGATTTTCTGCGTG
GCCGGCTGGCGGACGGCGTCGTGATCTTCCCCCCCCGGCCGCTGCGCGCGCTGGAACTCACGTCGCCGGAGCAGGTGCGC
GTGGTCATCCTCGGCCAGGACCCCTATCACGGCCGCGGCCAGGCGGAAGGGCTGGCCTTTTCGGTGGCGCCGGGCGTGCC
CCTGCCGCCGTCATTACGCAATATCTTCAAGGAGCTGCAGCGCGACCTGGGCACGCCACCGCCGGCGTTTCCGGTGCCCG
GCGGCAGCCTGGTGCGTTGGGCGACCCACGGCGTGCTGCTGCTCAACACCTGCCTGACGGTGGAGGAGGGGCTGCCGGCC
AGCCATGCGGGGCGCGGCTGGGAGGTCCTGACGGATGCGGTGATCCGGCAGGTTTCGCAGGGCGACCATCCGGTGGTGTT
CATGCTGTGGGGGGCGCATGCCCAAAGCAAGCGTGCGCTGATCGACGTTGGCCGCCACAAGGTGCTGGTGGCCAACCACC
CGTCACCGTTGTCGGCGCTGCGGCCGCCATTGCCTTTTATCGGCTGCGGGCATTTTTCGCAGGCGGTTGGCGGGCTCGAT
GGGGGCGGGCTGCCTTGGACGGTGATCTGA

Upstream 100 bases:

>100_bases
CAGGGTCAACGCCTTCCTGGTCGGCGAAGCCTTCATGCGGGCAGAAGATCCCGGCGTCGCGCTGGCTCAACTTTTCGGGC
TGGACTGACTGGCGCCGGCC

Downstream 100 bases:

>100_bases
CTCGCAGCAACTTTTCGGTGATGGGGTTTTATAAGTTGGTGCACACTGTCGGGTGAGCGTTCTGACCCTCATTGCTGCAG
ATGTTTGAAAGAGGGCGGAT

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTDLFLDEASALGVADRLTSADPLAWPVAPGWEPVTKAFFSSATGQKLLDFLRGRLADGVVIFPPRPLRALELTSPEQVR
VVILGQDPYHGRGQAEGLAFSVAPGVPLPPSLRNIFKELQRDLGTPPPAFPVPGGSLVRWATHGVLLLNTCLTVEEGLPA
SHAGRGWEVLTDAVIRQVSQGDHPVVFMLWGAHAQSKRALIDVGRHKVLVANHPSPLSALRPPLPFIGCGHFSQAVGGLD
GGGLPWTVI

Sequences:

>Translated_249_residues
MTDLFLDEASALGVADRLTSADPLAWPVAPGWEPVTKAFFSSATGQKLLDFLRGRLADGVVIFPPRPLRALELTSPEQVR
VVILGQDPYHGRGQAEGLAFSVAPGVPLPPSLRNIFKELQRDLGTPPPAFPVPGGSLVRWATHGVLLLNTCLTVEEGLPA
SHAGRGWEVLTDAVIRQVSQGDHPVVFMLWGAHAQSKRALIDVGRHKVLVANHPSPLSALRPPLPFIGCGHFSQAVGGLD
GGGLPWTVI
>Mature_248_residues
TDLFLDEASALGVADRLTSADPLAWPVAPGWEPVTKAFFSSATGQKLLDFLRGRLADGVVIFPPRPLRALELTSPEQVRV
VILGQDPYHGRGQAEGLAFSVAPGVPLPPSLRNIFKELQRDLGTPPPAFPVPGGSLVRWATHGVLLLNTCLTVEEGLPAS
HAGRGWEVLTDAVIRQVSQGDHPVVFMLWGAHAQSKRALIDVGRHKVLVANHPSPLSALRPPLPFIGCGHFSQAVGGLDG
GGLPWTVI

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=214, Percent_Identity=44.392523364486, Blast_Score=154, Evalue=5e-38,
Organism=Homo sapiens, GI6224979, Length=214, Percent_Identity=44.392523364486, Blast_Score=154, Evalue=6e-38,
Organism=Escherichia coli, GI1788934, Length=233, Percent_Identity=47.2103004291845, Blast_Score=177, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17556304, Length=217, Percent_Identity=40.5529953917051, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323620, Length=201, Percent_Identity=41.7910447761194, Blast_Score=128, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 26514; Mature: 26383

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLFLDEASALGVADRLTSADPLAWPVAPGWEPVTKAFFSSATGQKLLDFLRGRLADGV
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCE
VIFPPRPLRALELTSPEQVRVVILGQDPYHGRGQAEGLAFSVAPGVPLPPSLRNIFKELQ
EEECCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHH
RDLGTPPPAFPVPGGSLVRWATHGVLLLNTCLTVEEGLPASHAGRGWEVLTDAVIRQVSQ
HHCCCCCCCCCCCCCCEEHHHHCCEEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC
GDHPVVFMLWGAHAQSKRALIDVGRHKVLVANHPSPLSALRPPLPFIGCGHFSQAVGGLD
CCCCEEEEEECCCCCCCHHHEECCCCEEEEECCCCCHHHHCCCCCEEECCCHHHHHCCCC
GGGLPWTVI
CCCCCEEEC
>Mature Secondary Structure 
TDLFLDEASALGVADRLTSADPLAWPVAPGWEPVTKAFFSSATGQKLLDFLRGRLADGV
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCE
VIFPPRPLRALELTSPEQVRVVILGQDPYHGRGQAEGLAFSVAPGVPLPPSLRNIFKELQ
EEECCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHH
RDLGTPPPAFPVPGGSLVRWATHGVLLLNTCLTVEEGLPASHAGRGWEVLTDAVIRQVSQ
HHCCCCCCCCCCCCCCEEHHHHCCEEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC
GDHPVVFMLWGAHAQSKRALIDVGRHKVLVANHPSPLSALRPPLPFIGCGHFSQAVGGLD
CCCCEEEEEECCCCCCCHHHEECCCCEEEEECCCCCHHHHCCCCCEEECCCHHHHHCCCC
GGGLPWTVI
CCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA