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The map label for this gene is rpoB [H]

Identifier: 91790275

GI number: 91790275

Start: 4694415

End: 4698527

Strand: Reverse

Name: rpoB [H]

Synonym: Bpro_4442

Alternate gene names: 91790275

Gene position: 4698527-4694415 (Counterclockwise)

Preceding gene: 91790276

Following gene: 91790274

Centisome position: 90.35

GC content: 61.71

Gene sequence:

>4113_bases
ATGGCCTATTCCTATACCGAACGCAAACGCATCCGCAAAAGCTTCGGCAACCGCGAGAGCGTGTTGACTGTTCCCTATTT
GCTGCAAATGCAGAAAGACGCGTACACGGCGTTCCTGCAAGCCGATCGTGCGCCCCAGAAGCGCACTGTAGAAGGTCTGC
AGGCAGCGTTTGAAAACGCATTTCCCATCGTCTCGCACAACGGTTTTGTCGAGATGAAATTCATCGAATACAACCTGGCC
AAGCCCGCCTTCGACGTGCGCGAATGCCAGACCCGTGGACTGACCTTTGCATCGGCCGTCCGCGCCAAAGTCCAGCTGAT
CATCTATGACCGCGAGTCATCCACATCGCAGTCCAAGGTCGTCAAGGAGGTCAAGGAGCAGGAAGTCTACATGGGCGAAG
TGCCGCTCATGACCGACAAGGGCTCTTTCGTCATCAACGGGACCGAGCGCGTGATCGTGTCCCAGCTGCACCGCTCCCCT
GGCGTGTTCTTTGAACACGACAAGGGCAAAACCCACAGCTCGGGCAAACTGCTGTTCTCGGCCCGCATCATTCCCTATCG
CGGCTCCTGGCTCGACTTCGAGTTCGACCCGAAAGACGTGCTGTACTTCCGTGTCGACCGTCGCCGCAAGATGCCGGTCA
CGATCCTGCTCAAGGCCATCGGCCTGAACCCGGAATCCATCCTCGCCAACTTCTTCGTGTTCGACCACTTCCGCCTGATG
GACAGCGGCGCGCAGATGGAGTTTGTCGCCGAGCGCATGCGTGGCGAAGTGGCCCGTTTCGACATTACCGACAAGAGCGG
CAAGGTCGTCGTGGCCAAAGACAAGCGCATCACGGTTCGCCATACCCGCGAGCTGGAGCAAAGCGGCACCACCACCATCA
GCGTACCTGAAGACTTCCTGGTCGGCCGTGTGGTCGCCAAGAACATCGTCGACGCCGAAACCGGCGAAATCATCGCCAAG
GCCAACGACGAGCTGACCGAACTGCTGCTGAAAAAGCTGCGCCTGGCCGGCGTGCAGGACCTGCAGGTGCTGTACACCAA
CGAACTCGACCAGGGGGCCTACATTTCGCAAACCCTGCGCGCCGATGAAACGGCTGACGAGTTTGCGGCCCGCGTGGCCA
TCTACCGCATGATGCGTCCCGGCGAGCCGCCGACGGAAGACGCTGTGCAGGCACTGTTCCAGCGCCTGTTCTACAACCCG
GACACCTACGACCTGTCCAAGGTCGGCCGCATGAAGTTCAACGCCCGCGTGGGCCGTGACGACTCCACCGGCCCCATGGT
CATGACCAACGAGGACATCCTCGCGGTCGTCAAGATCCTGGTGGACCTGCGCAACGGCAACGGCGAAGTCGACGACATTG
ACCACCTCGGCAACCGCCGTGTGCGCTGCGTCGGCGAACTCGCGGAAAACCAGTACCGCACCGGTCTGGCCCGTATCGAG
AAGGCCGTGAAAGAGCGTCTGGGCCAGGCGGAGCAAGAGCCGCTGATGCCGCATGACCTGATCAACAGCAAGCCGATTTC
CGCCGCCCTGAAGGAATTCTTCGGTGCGTCGCAGCTGTCGCAGTTCATGGACCAGACCAACCCGCTGTCCGAGATCACCC
ACAAGCGCCGTGTTTCGGCCCTTGGCCCCGGTGGCTTGACCCGCGAGCGCGCCGGCTTCGAAGTGCGGGACGTGCACGTG
ACCCATTACGGCCGCGTCTGCCCGATTGAAACGCCTGAAGGTCCGAACATCGGCCTGATCAACTCGCTGGCCCTGTATGC
CCGCCTCAACGAGTACGGTTTCATCGAAACACCGTACCGCCGTGTGGTGGACAGCAAGATCACCGACCAGATCGATTACC
TGTCGGCCATTGAGGAAGGCAAGTACGTGATTGCCCAGGCCAACGCACTGCTCGATGATTCCGGCACACTGACCGGCGAC
CTCGTGTCAGCGCGCGAGAACGGCGAATCCGTGCTGGTCGGCGCAGAGCGCATCCAGTACATGGACGTGTCGCCCGCGCA
GATCGTCTCGGTGGCCGCCTCGCTCGTGCCCTTCCTGGAGCACGATGACGCCAACCGCGCACTGATGGGTGCCAACATGC
AGCGCCAGGCCGTGCCTGTGCTGCGCCCTGAAAAAGCCTTTGTCGGTACTGGCATCGAGCGCGTGTCCGCAGTGGACTCC
GGCACGGTGGTGACGGCCAACCGCGGCGGTGTGGTCGATTACGTCGATGCCACCCGCATCGTGGTGCGTGTCAATGATGC
GGAAGCCCTCGCCGGCGAAGTCGGTGTGGACATCTACAACCTGATCAAGTACCAGCGTTCCAACCAGAACACCAACATCC
ATCAGCGCCCCATCGTCAAGATCGGCGACAAGCTGGCCAAGGGCGACGTGATCGCCGACGGAGCATCGACGGACATCGGC
GAGCTGGCCCTGGGCCAGAACATGCTGGTGGCGTTCATGCCCTGGAACGGCTATAACTTCGAGGATTCGATCCTGATTTC
CGAGCGCGTGGTGGCCGAAGACCGCTACACCTCGATTCACATCGAAGAACTCGTGGTGATGGCGCGTGACACCAAGCTGG
GCTCTGAAGAGATCACCCGCGACATCCCGAACCTGTCCGAGCAGCAGCTCAACCGTCTCGACGAATCCGGCATTATTTAT
GTCGGCGCTGAAGTCCAGCCGGGCGACACCCTGGTGGGCAAGGTCACGCCAAAAGGCGAGACCACGCTGACGCCGGAAGA
AAAACTGCTGCGCGCCATCTTCGGCGAAAAAGCCAGCGACGTGAAAGACACCTCGCTGCGCGTGAGCCAGGGTTCGCAAG
GTACCGTGATCGACGTGCAGGTCTTCACTCGCGAAGGCATTGTGCGCGACAAGCGCGCCCAGCAGATCATTGACGACGAG
CTCAAGCGTTTCCGCCTGGACCTGAACGACCAGCTGCGCATTGTGGAAGCCGATGCATTTGACCGCATCGAAAAGCTGCT
GAATGGCAAGGTTGCCAACGGCGGCCCGAAAAAGCTGGCCAAAGGCACCAAGATCGACAAGGCCTACCTGGCCGACGTCG
AGAAGTACCACTGGTTCGACATCCGCCCGGCGGACGACGAAGTGGCTTCGCAGCTGGAAAGCATCAAGAACGCGATGGAG
CAGACGCGCCACAGCTTCGACCTGGCTTTCGAAGAGAAGCGCAAAAAGCTCACGCAGGGCGACGAACTGCCGGCCGGCGT
GCTCAAGATGGTCAAGGTCTACCTGGCCGTCAAGCGCCGCCTGCAGCCCGGCGACAAGATGGCCGGTCGCCACGGCAACA
AGGGCGTGGTGTCCAAGATCGTTCCGGTCGAAGACATGCCCTACATGGCCGACGGCACGCCGTGCGACATCGTGCTCAAC
CCGCTGGGCGTGCCTTCGCGCATGAACGTCGGCCAGGTGCTCGAGGTGCATTTGGGCTGGGCCGCCAAGGGTCTGGGCCA
GCGCATCGGCGACATGCTGCAAGCCGAAGCCAAGGTGGCCGAGCTGCGCAAGTTCATGGACACCCTGTACAACAAGTCGG
GCCGCGTCGAGGACCTGGCCAATCTGTCCGATACCGATGTGCTCGAGATGGCCCGCAACCTGACGACCGGTGTTCCCTTT
GCGACGCCGGTGTTCGATGGCGCCTCGGAAGAGGACATCATGACCATGCTGAAGCTGGCGTATCCGGACGACATCGCCAA
GGCCAAGGGCCTGACGGCGACGCGTACCCAGGCCCAGCTGTATGACGGGCGCACCGGCGACCAGTTCGAGCGCACGACGA
CGGTCGGCTACATGCACGTGCTGAAGCTTCACCACCTGGTGGACGACAAGATGCACGCGCGCTCAACCGGACCGTACTCC
CTGGTTACCCAGCAGCCGCTGGGCGGCAAGGCGCAGTTTGGTGGACAGCGTTTCGGCGAGATGGAGGTCTGGGCGCTGGA
AGCCTATGGCGCTTCCTACACGCTGCAGGAAATGCTCACCGTCAAGTCCGACGACGTGCAGGGCCGTACCAAGGTGTACG
AGAGCATCGTCAAGGGCGAGCACGCGATCACGGCAGGCATGCCCGAGTCGTTCAACGTGCTGGTCAAGGAGATCCGTTCG
CTCGGTATCGACATCGAGCTGGAACGCAGCTAA

Upstream 100 bases:

>100_bases
ACCGTCCGCCATGGTTGGTAGTGGCCAACCACCAAGCCTGCCTGAATACGTGGTGTATTCGGGCACGAGAGTCGCCAGAG
CCCATCAAAGCGGAGAACTC

Downstream 100 bases:

>100_bases
TTACAGGAAAGAAAAGGATTTAACTCATGAAATCATTACTCGACCTGTTCAAGCAATTCACGCCGGATGAGCATTTCGAT
GCCATCAAGATCGGCATGGC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1370; Mature: 1369

Protein sequence:

>1370_residues
MAYSYTERKRIRKSFGNRESVLTVPYLLQMQKDAYTAFLQADRAPQKRTVEGLQAAFENAFPIVSHNGFVEMKFIEYNLA
KPAFDVRECQTRGLTFASAVRAKVQLIIYDRESSTSQSKVVKEVKEQEVYMGEVPLMTDKGSFVINGTERVIVSQLHRSP
GVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLNPESILANFFVFDHFRLM
DSGAQMEFVAERMRGEVARFDITDKSGKVVVAKDKRITVRHTRELEQSGTTTISVPEDFLVGRVVAKNIVDAETGEIIAK
ANDELTELLLKKLRLAGVQDLQVLYTNELDQGAYISQTLRADETADEFAARVAIYRMMRPGEPPTEDAVQALFQRLFYNP
DTYDLSKVGRMKFNARVGRDDSTGPMVMTNEDILAVVKILVDLRNGNGEVDDIDHLGNRRVRCVGELAENQYRTGLARIE
KAVKERLGQAEQEPLMPHDLINSKPISAALKEFFGASQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHV
THYGRVCPIETPEGPNIGLINSLALYARLNEYGFIETPYRRVVDSKITDQIDYLSAIEEGKYVIAQANALLDDSGTLTGD
LVSARENGESVLVGAERIQYMDVSPAQIVSVAASLVPFLEHDDANRALMGANMQRQAVPVLRPEKAFVGTGIERVSAVDS
GTVVTANRGGVVDYVDATRIVVRVNDAEALAGEVGVDIYNLIKYQRSNQNTNIHQRPIVKIGDKLAKGDVIADGASTDIG
ELALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIHIEELVVMARDTKLGSEEITRDIPNLSEQQLNRLDESGIIY
VGAEVQPGDTLVGKVTPKGETTLTPEEKLLRAIFGEKASDVKDTSLRVSQGSQGTVIDVQVFTREGIVRDKRAQQIIDDE
LKRFRLDLNDQLRIVEADAFDRIEKLLNGKVANGGPKKLAKGTKIDKAYLADVEKYHWFDIRPADDEVASQLESIKNAME
QTRHSFDLAFEEKRKKLTQGDELPAGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPYMADGTPCDIVLN
PLGVPSRMNVGQVLEVHLGWAAKGLGQRIGDMLQAEAKVAELRKFMDTLYNKSGRVEDLANLSDTDVLEMARNLTTGVPF
ATPVFDGASEEDIMTMLKLAYPDDIAKAKGLTATRTQAQLYDGRTGDQFERTTTVGYMHVLKLHHLVDDKMHARSTGPYS
LVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYTLQEMLTVKSDDVQGRTKVYESIVKGEHAITAGMPESFNVLVKEIRS
LGIDIELERS

Sequences:

>Translated_1370_residues
MAYSYTERKRIRKSFGNRESVLTVPYLLQMQKDAYTAFLQADRAPQKRTVEGLQAAFENAFPIVSHNGFVEMKFIEYNLA
KPAFDVRECQTRGLTFASAVRAKVQLIIYDRESSTSQSKVVKEVKEQEVYMGEVPLMTDKGSFVINGTERVIVSQLHRSP
GVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLNPESILANFFVFDHFRLM
DSGAQMEFVAERMRGEVARFDITDKSGKVVVAKDKRITVRHTRELEQSGTTTISVPEDFLVGRVVAKNIVDAETGEIIAK
ANDELTELLLKKLRLAGVQDLQVLYTNELDQGAYISQTLRADETADEFAARVAIYRMMRPGEPPTEDAVQALFQRLFYNP
DTYDLSKVGRMKFNARVGRDDSTGPMVMTNEDILAVVKILVDLRNGNGEVDDIDHLGNRRVRCVGELAENQYRTGLARIE
KAVKERLGQAEQEPLMPHDLINSKPISAALKEFFGASQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHV
THYGRVCPIETPEGPNIGLINSLALYARLNEYGFIETPYRRVVDSKITDQIDYLSAIEEGKYVIAQANALLDDSGTLTGD
LVSARENGESVLVGAERIQYMDVSPAQIVSVAASLVPFLEHDDANRALMGANMQRQAVPVLRPEKAFVGTGIERVSAVDS
GTVVTANRGGVVDYVDATRIVVRVNDAEALAGEVGVDIYNLIKYQRSNQNTNIHQRPIVKIGDKLAKGDVIADGASTDIG
ELALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIHIEELVVMARDTKLGSEEITRDIPNLSEQQLNRLDESGIIY
VGAEVQPGDTLVGKVTPKGETTLTPEEKLLRAIFGEKASDVKDTSLRVSQGSQGTVIDVQVFTREGIVRDKRAQQIIDDE
LKRFRLDLNDQLRIVEADAFDRIEKLLNGKVANGGPKKLAKGTKIDKAYLADVEKYHWFDIRPADDEVASQLESIKNAME
QTRHSFDLAFEEKRKKLTQGDELPAGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPYMADGTPCDIVLN
PLGVPSRMNVGQVLEVHLGWAAKGLGQRIGDMLQAEAKVAELRKFMDTLYNKSGRVEDLANLSDTDVLEMARNLTTGVPF
ATPVFDGASEEDIMTMLKLAYPDDIAKAKGLTATRTQAQLYDGRTGDQFERTTTVGYMHVLKLHHLVDDKMHARSTGPYS
LVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYTLQEMLTVKSDDVQGRTKVYESIVKGEHAITAGMPESFNVLVKEIRS
LGIDIELERS
>Mature_1369_residues
AYSYTERKRIRKSFGNRESVLTVPYLLQMQKDAYTAFLQADRAPQKRTVEGLQAAFENAFPIVSHNGFVEMKFIEYNLAK
PAFDVRECQTRGLTFASAVRAKVQLIIYDRESSTSQSKVVKEVKEQEVYMGEVPLMTDKGSFVINGTERVIVSQLHRSPG
VFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLNPESILANFFVFDHFRLMD
SGAQMEFVAERMRGEVARFDITDKSGKVVVAKDKRITVRHTRELEQSGTTTISVPEDFLVGRVVAKNIVDAETGEIIAKA
NDELTELLLKKLRLAGVQDLQVLYTNELDQGAYISQTLRADETADEFAARVAIYRMMRPGEPPTEDAVQALFQRLFYNPD
TYDLSKVGRMKFNARVGRDDSTGPMVMTNEDILAVVKILVDLRNGNGEVDDIDHLGNRRVRCVGELAENQYRTGLARIEK
AVKERLGQAEQEPLMPHDLINSKPISAALKEFFGASQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHVT
HYGRVCPIETPEGPNIGLINSLALYARLNEYGFIETPYRRVVDSKITDQIDYLSAIEEGKYVIAQANALLDDSGTLTGDL
VSARENGESVLVGAERIQYMDVSPAQIVSVAASLVPFLEHDDANRALMGANMQRQAVPVLRPEKAFVGTGIERVSAVDSG
TVVTANRGGVVDYVDATRIVVRVNDAEALAGEVGVDIYNLIKYQRSNQNTNIHQRPIVKIGDKLAKGDVIADGASTDIGE
LALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIHIEELVVMARDTKLGSEEITRDIPNLSEQQLNRLDESGIIYV
GAEVQPGDTLVGKVTPKGETTLTPEEKLLRAIFGEKASDVKDTSLRVSQGSQGTVIDVQVFTREGIVRDKRAQQIIDDEL
KRFRLDLNDQLRIVEADAFDRIEKLLNGKVANGGPKKLAKGTKIDKAYLADVEKYHWFDIRPADDEVASQLESIKNAMEQ
TRHSFDLAFEEKRKKLTQGDELPAGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPYMADGTPCDIVLNP
LGVPSRMNVGQVLEVHLGWAAKGLGQRIGDMLQAEAKVAELRKFMDTLYNKSGRVEDLANLSDTDVLEMARNLTTGVPFA
TPVFDGASEEDIMTMLKLAYPDDIAKAKGLTATRTQAQLYDGRTGDQFERTTTVGYMHVLKLHHLVDDKMHARSTGPYSL
VTQQPLGGKAQFGGQRFGEMEVWALEAYGASYTLQEMLTVKSDDVQGRTKVYESIVKGEHAITAGMPESFNVLVKEIRSL
GIDIELERS

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI33469941, Length=260, Percent_Identity=32.6923076923077, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI212286172, Length=260, Percent_Identity=32.6923076923077, Blast_Score=117, Evalue=7e-26,
Organism=Homo sapiens, GI4505941, Length=312, Percent_Identity=28.2051282051282, Blast_Score=110, Evalue=7e-24,
Organism=Homo sapiens, GI238908505, Length=311, Percent_Identity=27.9742765273312, Blast_Score=95, Evalue=5e-19,
Organism=Homo sapiens, GI238908503, Length=311, Percent_Identity=27.9742765273312, Blast_Score=95, Evalue=5e-19,
Organism=Escherichia coli, GI1790419, Length=1371, Percent_Identity=63.3843909555069, Blast_Score=1780, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=256, Percent_Identity=30.078125, Blast_Score=110, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25144348, Length=304, Percent_Identity=29.2763157894737, Blast_Score=106, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17506623, Length=85, Percent_Identity=41.1764705882353, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324781, Length=305, Percent_Identity=29.5081967213115, Blast_Score=114, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6324725, Length=257, Percent_Identity=31.1284046692607, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6325267, Length=305, Percent_Identity=29.1803278688525, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI17647877, Length=304, Percent_Identity=28.9473684210526, Blast_Score=108, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17136444, Length=257, Percent_Identity=29.1828793774319, Blast_Score=103, Evalue=8e-22,
Organism=Drosophila melanogaster, GI17136446, Length=259, Percent_Identity=30.8880308880309, Blast_Score=103, Evalue=1e-21,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 152531; Mature: 152400

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSYTERKRIRKSFGNRESVLTVPYLLQMQKDAYTAFLQADRAPQKRTVEGLQAAFENA
CCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
FPIVSHNGFVEMKFIEYNLAKPAFDVRECQTRGLTFASAVRAKVQLIIYDRESSTSQSKV
CCEEECCCEEEEEEEEEECCCCCHHHHHHHHCCCHHHHHHCEEEEEEEEECCCCCHHHHH
VKEVKEQEVYMGEVPLMTDKGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFS
HHHHHHHHHEECCCCEEECCCCEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEE
ARIIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLNPESILANFFVFDHFRLM
EEEEEECCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
DSGAQMEFVAERMRGEVARFDITDKSGKVVVAKDKRITVRHTRELEQSGTTTISVPEDFL
CCCCHHHHHHHHHCCCEEEEEEECCCCCEEEEECCEEEEHHHHHHHHCCCEEEECCHHHH
VGRVVAKNIVDAETGEIIAKANDELTELLLKKLRLAGVQDLQVLYTNELDQGAYISQTLR
HHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHH
ADETADEFAARVAIYRMMRPGEPPTEDAVQALFQRLFYNPDTYDLSKVGRMKFNARVGRD
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEEECCC
DSTGPMVMTNEDILAVVKILVDLRNGNGEVDDIDHLGNRRVRCVGELAENQYRTGLARIE
CCCCCEEEECCHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KAVKERLGQAEQEPLMPHDLINSKPISAALKEFFGASQLSQFMDQTNPLSEITHKRRVSA
HHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHC
LGPGGLTRERAGFEVRDVHVTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFIETPYR
CCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
RVVDSKITDQIDYLSAIEEGKYVIAQANALLDDSGTLTGDLVSARENGESVLVGAERIQY
HHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCCHHHHHHCCCCCEEEEEHHHEEE
MDVSPAQIVSVAASLVPFLEHDDANRALMGANMQRQAVPVLRPEKAFVGTGIERVSAVDS
ECCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHCCCCCCCCCHHHHHCCHHHHHHCCC
GTVVTANRGGVVDYVDATRIVVRVNDAEALAGEVGVDIYNLIKYQRSNQNTNIHQRPIVK
CCEEEECCCCEEEEECCEEEEEEECCHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHH
IGDKLAKGDVIADGASTDIGELALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIH
HCCHHHCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCEEEHHHHHHCCCCCEEE
IEELVVMARDTKLGSEEITRDIPNLSEQQLNRLDESGIIYVGAEVQPGDTLVGKVTPKGE
HHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHCCCCCEEEEECEECCCCCEEEEECCCCC
TTLTPEEKLLRAIFGEKASDVKDTSLRVSQGSQGTVIDVQVFTREGIVRDKRAQQIIDDE
CCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHH
LKRFRLDLNDQLRIVEADAFDRIEKLLNGKVANGGPKKLAKGTKIDKAYLADVEKYHWFD
HHHHHCCCCCCEEEEECHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHEEEE
IRPADDEVASQLESIKNAMEQTRHSFDLAFEEKRKKLTQGDELPAGVLKMVKVYLAVKRR
CCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LQPGDKMAGRHGNKGVVSKIVPVEDMPYMADGTPCDIVLNPLGVPSRMNVGQVLEVHLGW
CCCCHHHCCCCCCCCCHHEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEHHCH
AAKGLGQRIGDMLQAEAKVAELRKFMDTLYNKSGRVEDLANLSDTDVLEMARNLTTGVPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCCCCC
ATPVFDGASEEDIMTMLKLAYPDDIAKAKGLTATRTQAQLYDGRTGDQFERTTTVGYMHV
CCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCEECCHHHHHCCCCCCCHHHHHHHHHHHH
LKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYTLQEMLT
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHH
VKSDDVQGRTKVYESIVKGEHAITAGMPESFNVLVKEIRSLGIDIELERS
HCCCCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
AYSYTERKRIRKSFGNRESVLTVPYLLQMQKDAYTAFLQADRAPQKRTVEGLQAAFENA
CCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
FPIVSHNGFVEMKFIEYNLAKPAFDVRECQTRGLTFASAVRAKVQLIIYDRESSTSQSKV
CCEEECCCEEEEEEEEEECCCCCHHHHHHHHCCCHHHHHHCEEEEEEEEECCCCCHHHHH
VKEVKEQEVYMGEVPLMTDKGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFS
HHHHHHHHHEECCCCEEECCCCEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEE
ARIIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLNPESILANFFVFDHFRLM
EEEEEECCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
DSGAQMEFVAERMRGEVARFDITDKSGKVVVAKDKRITVRHTRELEQSGTTTISVPEDFL
CCCCHHHHHHHHHCCCEEEEEEECCCCCEEEEECCEEEEHHHHHHHHCCCEEEECCHHHH
VGRVVAKNIVDAETGEIIAKANDELTELLLKKLRLAGVQDLQVLYTNELDQGAYISQTLR
HHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHH
ADETADEFAARVAIYRMMRPGEPPTEDAVQALFQRLFYNPDTYDLSKVGRMKFNARVGRD
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEEECCC
DSTGPMVMTNEDILAVVKILVDLRNGNGEVDDIDHLGNRRVRCVGELAENQYRTGLARIE
CCCCCEEEECCHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KAVKERLGQAEQEPLMPHDLINSKPISAALKEFFGASQLSQFMDQTNPLSEITHKRRVSA
HHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHC
LGPGGLTRERAGFEVRDVHVTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFIETPYR
CCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
RVVDSKITDQIDYLSAIEEGKYVIAQANALLDDSGTLTGDLVSARENGESVLVGAERIQY
HHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCCHHHHHHCCCCCEEEEEHHHEEE
MDVSPAQIVSVAASLVPFLEHDDANRALMGANMQRQAVPVLRPEKAFVGTGIERVSAVDS
ECCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHCCCCCCCCCHHHHHCCHHHHHHCCC
GTVVTANRGGVVDYVDATRIVVRVNDAEALAGEVGVDIYNLIKYQRSNQNTNIHQRPIVK
CCEEEECCCCEEEEECCEEEEEEECCHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHH
IGDKLAKGDVIADGASTDIGELALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIH
HCCHHHCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCEEEHHHHHHCCCCCEEE
IEELVVMARDTKLGSEEITRDIPNLSEQQLNRLDESGIIYVGAEVQPGDTLVGKVTPKGE
HHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHCCCCCEEEEECEECCCCCEEEEECCCCC
TTLTPEEKLLRAIFGEKASDVKDTSLRVSQGSQGTVIDVQVFTREGIVRDKRAQQIIDDE
CCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHH
LKRFRLDLNDQLRIVEADAFDRIEKLLNGKVANGGPKKLAKGTKIDKAYLADVEKYHWFD
HHHHHCCCCCCEEEEECHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHEEEE
IRPADDEVASQLESIKNAMEQTRHSFDLAFEEKRKKLTQGDELPAGVLKMVKVYLAVKRR
CCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LQPGDKMAGRHGNKGVVSKIVPVEDMPYMADGTPCDIVLNPLGVPSRMNVGQVLEVHLGW
CCCCHHHCCCCCCCCCHHEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEHHCH
AAKGLGQRIGDMLQAEAKVAELRKFMDTLYNKSGRVEDLANLSDTDVLEMARNLTTGVPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCCCCC
ATPVFDGASEEDIMTMLKLAYPDDIAKAKGLTATRTQAQLYDGRTGDQFERTTTVGYMHV
CCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCEECCHHHHHCCCCCCCHHHHHHHHHHHH
LKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYTLQEMLT
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHH
VKSDDVQGRTKVYESIVKGEHAITAGMPESFNVLVKEIRSLGIDIELERS
HCCCCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA