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The map label for this gene is yhcS [C]

Identifier: 91790128

GI number: 91790128

Start: 4526439

End: 4527365

Strand: Direct

Name: yhcS [C]

Synonym: Bpro_4290

Alternate gene names: 91790128

Gene position: 4526439-4527365 (Clockwise)

Preceding gene: 91790126

Following gene: 91790130

Centisome position: 87.04

GC content: 64.4

Gene sequence:

>927_bases
ATGGACCGGCTTCAATCAATGCGCGTGTTTCAACAGGTGGTGGACGACGGCAGCTTTGCCGCTGCCGCCCGTAAATTCGA
CCTGTCGTCGGCCGTGGTGACCCGGCTGGTCAGCGACCTGGAAGACCATCTGGGCGTGCGGCTGCTGCATCGCACCACCC
GGCGCATGGCACTGACGGATGCAGGTGTTGCCTACCTGGCTCGCGTGCGCCACATCCTGAGCGACATCGACGAGGCCCAC
GCGGCGGCGCAGGCGCATGCCCAGGAGATGTCCGGCGTGATCCGCATCCTGACGCCGCCCATCTTCGGTGTGCATGTGCT
GGGGCCGCTGGTGGCCGAGTTCGGGCGACGCTATCCCAAGGTCGTGCTCGATATTTACGTCGACTCGCCGCTCGTGCCGC
CGGTGGAAGACTACGACCTGACGCTGCTGGGCGCGACCGATACCTTTGACGCCAACATCATTGCGCGGCCGATTGCCTCG
TCGGACGGCATCCTGTGCGCCTCACCCGACTACCTGCGCCGCAATGGCATTCCGCAGCAGCCCGAAGACCTCGCCCGGCA
CCGCTGCCTGCGGATCAAGGCACCGGCGAACCGGCACCGCGTCTGGCGCCTCATCAATCCCGACGAGAATAGGCGCGAAC
TGGAAGTGCCGATCGAGCCCGCCATGCTGGTCAACCATTCCGACACGCTGATACGCGCCGGTGTCGACGGAGCCGGCATC
ATCAGCCAGTCGATCGACCTGGTGGCCAACCACCTCCACAGCGGCGCGCTGAAACGAATCCTGTCGCCCTGGATCACGGG
CACCAACACCCTGTACGCGGCGCTGCCCAGCCGCAAATTCATTCCGGCAAGAACCAGCGTGTTTCTGGAATTCATGACCG
AGTACACGCGAACTGTGATCAAGAAAATGGACGCGCGGCACGACTGA

Upstream 100 bases:

>100_bases
TGGACGAACTTTATTCCACTCAAGCAAATCAAAAAACAGCAAAATTAACAATTTATTGCTGCTAAAACAGCAATAATGAA
GCGAAAAGCAAGGGTATTCC

Downstream 100 bases:

>100_bases
GCTGAGCCTTTACCGCGCACACAAGGCCATCGCCCCGCGGCCGCGGCCGGTATGGAAGACCGGCCATCAGTCCCCATATG
GCATGAGGGACTGGCACGTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDRLQSMRVFQQVVDDGSFAAAARKFDLSSAVVTRLVSDLEDHLGVRLLHRTTRRMALTDAGVAYLARVRHILSDIDEAH
AAAQAHAQEMSGVIRILTPPIFGVHVLGPLVAEFGRRYPKVVLDIYVDSPLVPPVEDYDLTLLGATDTFDANIIARPIAS
SDGILCASPDYLRRNGIPQQPEDLARHRCLRIKAPANRHRVWRLINPDENRRELEVPIEPAMLVNHSDTLIRAGVDGAGI
ISQSIDLVANHLHSGALKRILSPWITGTNTLYAALPSRKFIPARTSVFLEFMTEYTRTVIKKMDARHD

Sequences:

>Translated_308_residues
MDRLQSMRVFQQVVDDGSFAAAARKFDLSSAVVTRLVSDLEDHLGVRLLHRTTRRMALTDAGVAYLARVRHILSDIDEAH
AAAQAHAQEMSGVIRILTPPIFGVHVLGPLVAEFGRRYPKVVLDIYVDSPLVPPVEDYDLTLLGATDTFDANIIARPIAS
SDGILCASPDYLRRNGIPQQPEDLARHRCLRIKAPANRHRVWRLINPDENRRELEVPIEPAMLVNHSDTLIRAGVDGAGI
ISQSIDLVANHLHSGALKRILSPWITGTNTLYAALPSRKFIPARTSVFLEFMTEYTRTVIKKMDARHD
>Mature_308_residues
MDRLQSMRVFQQVVDDGSFAAAARKFDLSSAVVTRLVSDLEDHLGVRLLHRTTRRMALTDAGVAYLARVRHILSDIDEAH
AAAQAHAQEMSGVIRILTPPIFGVHVLGPLVAEFGRRYPKVVLDIYVDSPLVPPVEDYDLTLLGATDTFDANIIARPIAS
SDGILCASPDYLRRNGIPQQPEDLARHRCLRIKAPANRHRVWRLINPDENRRELEVPIEPAMLVNHSDTLIRAGVDGAGI
ISQSIDLVANHLHSGALKRILSPWITGTNTLYAALPSRKFIPARTSVFLEFMTEYTRTVIKKMDARHD

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=308, Percent_Identity=29.5454545454545, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=29.3918918918919, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=31.2292358803987, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=31.2925170068027, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787128, Length=294, Percent_Identity=26.1904761904762, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789440, Length=300, Percent_Identity=26.3333333333333, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787589, Length=296, Percent_Identity=28.7162162162162, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789173, Length=270, Percent_Identity=25.5555555555556, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788748, Length=118, Percent_Identity=34.7457627118644, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786448, Length=295, Percent_Identity=23.0508474576271, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789506, Length=173, Percent_Identity=25.4335260115607, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI157672245, Length=153, Percent_Identity=30.0653594771242, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787879, Length=122, Percent_Identity=34.4262295081967, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788706, Length=300, Percent_Identity=21.3333333333333, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34297; Mature: 34297

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLQSMRVFQQVVDDGSFAAAARKFDLSSAVVTRLVSDLEDHLGVRLLHRTTRRMALTD
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVAYLARVRHILSDIDEAHAAAQAHAQEMSGVIRILTPPIFGVHVLGPLVAEFGRRYPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHCCCCE
VVLDIYVDSPLVPPVEDYDLTLLGATDTFDANIIARPIASSDGILCASPDYLRRNGIPQQ
EEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCCEEECCCHHHHHCCCCCC
PEDLARHRCLRIKAPANRHRVWRLINPDENRRELEVPIEPAMLVNHSDTLIRAGVDGAGI
HHHHHHHHEEEECCCCCCCCEEEEECCCCCCCEEECCCCCEEEECCCCCEEEECCCCCHH
ISQSIDLVANHLHSGALKRILSPWITGTNTLYAALPSRKFIPARTSVFLEFMTEYTRTVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
KKMDARHD
HHHHCCCC
>Mature Secondary Structure
MDRLQSMRVFQQVVDDGSFAAAARKFDLSSAVVTRLVSDLEDHLGVRLLHRTTRRMALTD
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVAYLARVRHILSDIDEAHAAAQAHAQEMSGVIRILTPPIFGVHVLGPLVAEFGRRYPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHCCCCE
VVLDIYVDSPLVPPVEDYDLTLLGATDTFDANIIARPIASSDGILCASPDYLRRNGIPQQ
EEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCCEEECCCHHHHHCCCCCC
PEDLARHRCLRIKAPANRHRVWRLINPDENRRELEVPIEPAMLVNHSDTLIRAGVDGAGI
HHHHHHHHEEEECCCCCCCCEEEEECCCCCCCEEECCCCCEEEECCCCCEEEECCCCCHH
ISQSIDLVANHLHSGALKRILSPWITGTNTLYAALPSRKFIPARTSVFLEFMTEYTRTVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
KKMDARHD
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]