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The map label for this gene is csgA [H]

Identifier: 91790024

GI number: 91790024

Start: 4398767

End: 4399435

Strand: Reverse

Name: csgA [H]

Synonym: Bpro_4186

Alternate gene names: 91790024

Gene position: 4399435-4398767 (Counterclockwise)

Preceding gene: 91790025

Following gene: 91790023

Centisome position: 84.6

GC content: 68.61

Gene sequence:

>669_bases
ATGAGCACGGTGCTGGTCATAGGCGCTTCCCGCGGGATTGGCCTGGAACTGGTCCGCCAGTACCGCGAGGCCGGCGACCG
CGTGATCGCCACGGCACGCGACGATGCCGGCCTGCAGCGGCTGCGCGCGCTCGATGCCCACGCCTTGAAGGTGGATGTGA
CTGATCCGGCCAGTGTCAGCGGCCTGGCCTGGCAGCTGGATGGTGAGAAACTTGACGTGGCCCTGTACGTGGCGGGCGTC
TACACCACGGCGGGCGCCACCACGCCGCCCACGCGCGAGGAATTTGACCGCGCCCTGCACACCAACGTGCTGGGGGCGAT
GCAGGCCATCCCGCAGGTCGCGCCGCTGGTGGAGGCGGCGGGCGGCAAGTTTGTCTTCGTCACCAGCGGCATGGGGCGGA
TCGGCGGGGTGGGCTCCAGCTTTGGCTGGACTTACCGCGTCAGCAAGGCCGCACTCAACATGGCCGTGGTTGCGGCCCAG
CACGACTACCCCCAAGCCATTCTGGCGGCGCTGTCGCCCGGCTGGGTGCGGACCGATATGGGCGGTCCGGGTGCGCCGCT
GGCGGTCAGCGACAGCGTGGCCGCCCTGCGCAAAACCATTGCCTCGCTGAAGGCCCAACACAAAGGCGCGTTCCTCGACT
ATGACGGGCGCCCATTCGAATCATGGTGA

Upstream 100 bases:

>100_bases
ACGGCGCTGGCGGTTGAGCTGATGTAATGTTTTGTCGTCAGGTCTGCTGGCCGCATCCGCGCGAGGTGGCCCGGACTGGC
TTCTACATGAGATCTTTCGC

Downstream 100 bases:

>100_bases
CCACATGCTGTTGACACAAGACCAGGAATTGATCCGCGACGCCGTGCGTGCCTTTGCGCAGCAAGAGCTCTGGCCCCACG
CCGCCCGCTGGGACAAGGAG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSTVLVIGASRGIGLELVRQYREAGDRVIATARDDAGLQRLRALDAHALKVDVTDPASVSGLAWQLDGEKLDVALYVAGV
YTTAGATTPPTREEFDRALHTNVLGAMQAIPQVAPLVEAAGGKFVFVTSGMGRIGGVGSSFGWTYRVSKAALNMAVVAAQ
HDYPQAILAALSPGWVRTDMGGPGAPLAVSDSVAALRKTIASLKAQHKGAFLDYDGRPFESW

Sequences:

>Translated_222_residues
MSTVLVIGASRGIGLELVRQYREAGDRVIATARDDAGLQRLRALDAHALKVDVTDPASVSGLAWQLDGEKLDVALYVAGV
YTTAGATTPPTREEFDRALHTNVLGAMQAIPQVAPLVEAAGGKFVFVTSGMGRIGGVGSSFGWTYRVSKAALNMAVVAAQ
HDYPQAILAALSPGWVRTDMGGPGAPLAVSDSVAALRKTIASLKAQHKGAFLDYDGRPFESW
>Mature_221_residues
STVLVIGASRGIGLELVRQYREAGDRVIATARDDAGLQRLRALDAHALKVDVTDPASVSGLAWQLDGEKLDVALYVAGVY
TTAGATTPPTREEFDRALHTNVLGAMQAIPQVAPLVEAAGGKFVFVTSGMGRIGGVGSSFGWTYRVSKAALNMAVVAAQH
DYPQAILAALSPGWVRTDMGGPGAPLAVSDSVAALRKTIASLKAQHKGAFLDYDGRPFESW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17559962, Length=239, Percent_Identity=28.0334728033473, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17559964, Length=239, Percent_Identity=29.2887029288703, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17558990, Length=245, Percent_Identity=29.3877551020408, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI193207563, Length=248, Percent_Identity=30.241935483871, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17558994, Length=247, Percent_Identity=27.9352226720648, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17558992, Length=245, Percent_Identity=29.7959183673469, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17541382, Length=246, Percent_Identity=27.2357723577236, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI72001658, Length=242, Percent_Identity=28.099173553719, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17542178, Length=239, Percent_Identity=26.7782426778243, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17532177, Length=239, Percent_Identity=25.5230125523013, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640547, Length=245, Percent_Identity=28.9795918367347, Blast_Score=101, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23306; Mature: 23175

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVLVIGASRGIGLELVRQYREAGDRVIATARDDAGLQRLRALDAHALKVDVTDPASVS
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCC
GLAWQLDGEKLDVALYVAGVYTTAGATTPPTREEFDRALHTNVLGAMQAIPQVAPLVEAA
CEEEEECCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGKFVFVTSGMGRIGGVGSSFGWTYRVSKAALNMAVVAAQHDYPQAILAALSPGWVRTDM
CCCEEEEECCCCCCCCCCCCCCEEEEEHHHHHEEEEEEECCCCHHHHHHHCCCCCEEECC
GGPGAPLAVSDSVAALRKTIASLKAQHKGAFLDYDGRPFESW
CCCCCCEEECHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCC
>Mature Secondary Structure 
STVLVIGASRGIGLELVRQYREAGDRVIATARDDAGLQRLRALDAHALKVDVTDPASVS
CEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCC
GLAWQLDGEKLDVALYVAGVYTTAGATTPPTREEFDRALHTNVLGAMQAIPQVAPLVEAA
CEEEEECCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGKFVFVTSGMGRIGGVGSSFGWTYRVSKAALNMAVVAAQHDYPQAILAALSPGWVRTDM
CCCEEEEECCCCCCCCCCCCCCEEEEEHHHHHEEEEEEECCCCHHHHHHHCCCCCEEECC
GGPGAPLAVSDSVAALRKTIASLKAQHKGAFLDYDGRPFESW
CCCCCCEEECHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]