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The map label for this gene is 91789878

Identifier: 91789878

GI number: 91789878

Start: 4239332

End: 4239724

Strand: Direct

Name: 91789878

Synonym: Bpro_4038

Alternate gene names: NA

Gene position: 4239332-4239724 (Clockwise)

Preceding gene: 91789877

Following gene: 91789879

Centisome position: 81.52

GC content: 59.8

Gene sequence:

>393_bases
GTGACCGATCATCTGGATCATCTGGTACTGACCACGTCCAACGAAACCGCCTGCGTCGATTTTTATACCCGGGTGCTGGG
CATGACGCTGGAAAGTTTTGTGGGTGGTACGCCCCCGGTAGAGCGCCGCGCATTCAAGTTCGGCCAGCAGAAAATCAACC
TGCACATCAGAGGCGCCGAGTTCGAGCCCAAAACGCATCTGCCGGTGCCCGGTGCACTGGACTTGTGTTTCATCGCCAGC
GTGCCCCTGCAGCAGGTGATGGAGCGGCTGGAGCGCGAACGCTGGCCGATTATCGAAGGGCCCGTTGTACGCACCGGCGC
CACGCAAAAAATCCGCTCGGTCTATGTGCGCAACCCCGACCTCAACCTGATCGAGATTTCCGAGCTGGCCTGA

Upstream 100 bases:

>100_bases
TCGTCGGCCACGAGGTACCGGGCCAGGTGGCCAAGGCGGGGCGCATTGAAGACCTGCATCCGGCGCCGGAATTTGTGGCG
GCCCTGCGGGAGCAGTTCGC

Downstream 100 bases:

>100_bases
ACCGGCATCCATCACCATTCCAGGAGACAAAATGACTTTCATTTCCCGCAGAACCCTTGTAACCGTTGCCGGCCTTGCCG
CTGCCTCATGGCTGAACCCG

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MTDHLDHLVLTTSNETACVDFYTRVLGMTLESFVGGTPPVERRAFKFGQQKINLHIRGAEFEPKTHLPVPGALDLCFIAS
VPLQQVMERLERERWPIIEGPVVRTGATQKIRSVYVRNPDLNLIEISELA

Sequences:

>Translated_130_residues
MTDHLDHLVLTTSNETACVDFYTRVLGMTLESFVGGTPPVERRAFKFGQQKINLHIRGAEFEPKTHLPVPGALDLCFIAS
VPLQQVMERLERERWPIIEGPVVRTGATQKIRSVYVRNPDLNLIEISELA
>Mature_129_residues
TDHLDHLVLTTSNETACVDFYTRVLGMTLESFVGGTPPVERRAFKFGQQKINLHIRGAEFEPKTHLPVPGALDLCFIASV
PLQQVMERLERERWPIIEGPVVRTGATQKIRSVYVRNPDLNLIEISELA

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=123, Percent_Identity=47.9674796747967, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14683; Mature: 14552

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHLDHLVLTTSNETACVDFYTRVLGMTLESFVGGTPPVERRAFKFGQQKINLHIRGAE
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEEECCC
FEPKTHLPVPGALDLCFIASVPLQQVMERLERERWPIIEGPVVRTGATQKIRSVYVRNPD
CCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCHHHHHEEEEECCC
LNLIEISELA
CCEEEECCCC
>Mature Secondary Structure 
TDHLDHLVLTTSNETACVDFYTRVLGMTLESFVGGTPPVERRAFKFGQQKINLHIRGAE
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEEECCC
FEPKTHLPVPGALDLCFIASVPLQQVMERLERERWPIIEGPVVRTGATQKIRSVYVRNPD
CCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCHHHHHEEEEECCC
LNLIEISELA
CCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]