Click here to switch to the map view.

The map label for this gene is uxuR [H]

Identifier: 91789817

GI number: 91789817

Start: 4170006

End: 4170743

Strand: Direct

Name: uxuR [H]

Synonym: Bpro_3977

Alternate gene names: 91789817

Gene position: 4170006-4170743 (Clockwise)

Preceding gene: 91789809

Following gene: 91789818

Centisome position: 80.19

GC content: 65.18

Gene sequence:

>738_bases
ATGAACCTCCAACTCATTCCCGCTGCCGCTGCAAAACCTTCCACTGAAGAGACCGACGTCGAGCGGCCCTACCTGCGGCT
GGCCGCGCAGATTCTGGCGCTGCTGGCGCACAAGGGCGTCAAGGCGGGCGAACGCCTGCCGTCGGAACGGGCCCTGGCCG
AACAGTTCGAGGTCAGTCGCACCTCGGTGCGCGAAGCCATCATTGCGCTGGAACTGCAGGGAGCCGTCGAGGTCAGGGGC
GGCTCCGGCGCCTATGTGATCCAGACCCCGGCGACGGCGACACAAACCCCGGTCTTCATGCCAGAGGCAGGGCCGGGGCC
GTTTGAGCTGTTGCGCGCACGCTGCCTGATCGAATCTGAAATCGCCTCTGTGGCTGCGGAGACGCGCAAGGACGCCGATC
TGGACCGCATCTTCGAGGCCCTGGCCGATATGCGCCTGCACATGGACGACAAGGTGGCCAACGAAGCCGCCGACCGCCGG
TTTCATCTGTATATCGCGGAGTCCACCGGCAACAGCGTTTTGCTGCAGATGGTGACCGCGATGTGGGACCATGCCAAAGG
CCCCGTGTGGGCCAAGATTGACCAGCACTTTCACAGCCCGGCCCTGCGCGTGTCGTCGCAGGAAGACCATCAGCGCGTCT
TCGATGCGCTGATGGCGCGAGACCCCGTAGCGGCACGCACCGCCATGCGCGCTCACCTGGAGCGCGTGATCAAGGAATTC
GCCCAGGCCTGGCGCTAA

Upstream 100 bases:

>100_bases
AACGCCCTGTTGAACGGTCAGAATCGGCGGTCTCTGGCCTAATTGGTAAACCATCTTCATTTTTTGTGCCTGACAGGCCG
GCCCTTCTGGCGCCCCTCTT

Downstream 100 bases:

>100_bases
ACAGCGGCCCGGTCCCCCGCCCCGTCCATTCACTGAAACCCCAGCACGCATCATGAAAATCACCAACGCCCGCGTCATCG
TCTGCAGCCCCGGCCGCAAC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNLQLIPAAAAKPSTEETDVERPYLRLAAQILALLAHKGVKAGERLPSERALAEQFEVSRTSVREAIIALELQGAVEVRG
GSGAYVIQTPATATQTPVFMPEAGPGPFELLRARCLIESEIASVAAETRKDADLDRIFEALADMRLHMDDKVANEAADRR
FHLYIAESTGNSVLLQMVTAMWDHAKGPVWAKIDQHFHSPALRVSSQEDHQRVFDALMARDPVAARTAMRAHLERVIKEF
AQAWR

Sequences:

>Translated_245_residues
MNLQLIPAAAAKPSTEETDVERPYLRLAAQILALLAHKGVKAGERLPSERALAEQFEVSRTSVREAIIALELQGAVEVRG
GSGAYVIQTPATATQTPVFMPEAGPGPFELLRARCLIESEIASVAAETRKDADLDRIFEALADMRLHMDDKVANEAADRR
FHLYIAESTGNSVLLQMVTAMWDHAKGPVWAKIDQHFHSPALRVSSQEDHQRVFDALMARDPVAARTAMRAHLERVIKEF
AQAWR
>Mature_245_residues
MNLQLIPAAAAKPSTEETDVERPYLRLAAQILALLAHKGVKAGERLPSERALAEQFEVSRTSVREAIIALELQGAVEVRG
GSGAYVIQTPATATQTPVFMPEAGPGPFELLRARCLIESEIASVAAETRKDADLDRIFEALADMRLHMDDKVANEAADRR
FHLYIAESTGNSVLLQMVTAMWDHAKGPVWAKIDQHFHSPALRVSSQEDHQRVFDALMARDPVAARTAMRAHLERVIKEF
AQAWR

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=223, Percent_Identity=39.4618834080717, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI87082208, Length=223, Percent_Identity=37.6681614349776, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1790032, Length=219, Percent_Identity=35.1598173515982, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789353, Length=230, Percent_Identity=27.8260869565217, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789621, Length=201, Percent_Identity=32.3383084577114, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786303, Length=221, Percent_Identity=31.2217194570136, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27098; Mature: 27098

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQLIPAAAAKPSTEETDVERPYLRLAAQILALLAHKGVKAGERLPSERALAEQFEVSR
CCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHH
TSVREAIIALELQGAVEVRGGSGAYVIQTPATATQTPVFMPEAGPGPFELLRARCLIESE
HHHHHHHHHHEECCEEEEECCCCEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHHHHHH
IASVAAETRKDADLDRIFEALADMRLHMDDKVANEAADRRFHLYIAESTGNSVLLQMVTA
HHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHH
MWDHAKGPVWAKIDQHFHSPALRVSSQEDHQRVFDALMARDPVAARTAMRAHLERVIKEF
HHHHCCCCEEHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AQAWR
HHHCC
>Mature Secondary Structure
MNLQLIPAAAAKPSTEETDVERPYLRLAAQILALLAHKGVKAGERLPSERALAEQFEVSR
CCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHH
TSVREAIIALELQGAVEVRGGSGAYVIQTPATATQTPVFMPEAGPGPFELLRARCLIESE
HHHHHHHHHHEECCEEEEECCCCEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHHHHHH
IASVAAETRKDADLDRIFEALADMRLHMDDKVANEAADRRFHLYIAESTGNSVLLQMVTA
HHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHH
MWDHAKGPVWAKIDQHFHSPALRVSSQEDHQRVFDALMARDPVAARTAMRAHLERVIKEF
HHHHCCCCEEHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AQAWR
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]