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The map label for this gene is otsA [H]

Identifier: 91789759

GI number: 91789759

Start: 4112568

End: 4113950

Strand: Direct

Name: otsA [H]

Synonym: Bpro_3918

Alternate gene names: 91789759

Gene position: 4112568-4113950 (Clockwise)

Preceding gene: 91789758

Following gene: 91789767

Centisome position: 79.08

GC content: 64.93

Gene sequence:

>1383_bases
ATGAGCCGGCTGGTTGTGGTGTCCAACCGCGTGGCGGATCCGCGCAAGACGGCGGCCGGCGGCCTGGCTGTGGCGCTGGG
CGATGCGCTCAATGCCACGGGCGGCATGTGGTTTGGCTGGAGCGGCACCGTCATCGAAGGCGGTGCCCCGGGCGAAGGCG
AGCTGCATGTGCAGCAGGCGGGCAACGTCAAGCTGGCCACCGTGGATTTGTCCGCCGAAGACCATGCCGGCTATTACCTG
GGCTACAGCAATGGCGTGCTCTGGCCGGTGTTTCACTACCGGATCGACCTGGCGCGCTTTGACGCCGGCAACATCCGCGC
CTATCGCCGCGTCAACCAGCTGTTTGCGCGCAAGCTGATGACGCAGCTGCGGCCGGACGACATCATCTGGGTGCATGACT
ACCACCTGATTCCGCTGGCGGCCGAGCTGCGCGCCATGGGCGCCACCCAGCGCATCGGATTTTTCCTGCACATTCCCCTG
CCGCCGCAGCAGGTGCTGGCGGCCATTCCCCAACACGAATGGCTGATGCGGGCCATGTTTGCCTACGACCTGTTGGGCTT
TCAGAGCGAGGCCGACCTGCAAAACTTTTCGCACTATGTGCAGGCCGAGGCCGGCGCCGAGGACCTGGGCGACAACCGGT
TTCGCGCCTTCAACCGCACCGTGCGCGCCGGCGCCTTCCCGATTGGCATTGACGTGGACGAATTCGCCGCGCTCACCCAT
GCCAAGGAGGGGCACGACATGTATGAACGCATGAAGGACGAATACTCGCGCCGCAAATTGCTGCTGGGCGTGGAACGCCT
GGACTATTCAAAAGGCCTGCCCCAGCGCCTGCGCGCATTCAAGAGCCTGCTTGAAAAATACCCGGAAAACATCCGCAGCG
CCACGCTGATCCAGATCGCCTCACCGAGCCGCGAAGACATGGGCACGTACACCGACTTGCTGCAAGAGCTCGAGAGCCTG
TGCGGCGCCATCAACGGCGACTTTGGCGAGCTGGACTGGATGCCGGTGCGCTACATGCACCGCAACGTGGCGCGCAAACG
CCTGCCCGGTCTCTACCGCGTGGCGCGCGTGGCGCTGGTGACGCCGCTGCGCGACGGAATGAACCTGGTGGCCAAGGAGT
TCATTGCCGCGCAGGACCCGGCCGATCCGGGTGTGCTGGTGCTGTCACGCTTTGCCGGCGCCGCCGAGCAGCTGAAGGAA
GCCCTGCTGGTGAACCCGTACGACACGGACGGCACGGCAGACACCATCCAGCACGCCCTGCAGATGTCGCTGCAGGAGCG
GCAGGGACGGCACCAGAGGCTGCTGAAAAATATCCGGGAGCAGGATGTGCACTGGTGGCGCAAGACATTCCTGGACACGC
TGCGCGACGCCGGAAGTGACTAG

Upstream 100 bases:

>100_bases
TTGAGCAGGTTGGGACAGGCGACAGAGGCGAAGCGTCTGGCGAGCCGCGGCCTGCAAGGCCTCGTGCAGTACACGAAGTG
ACAAGCGTGGGGGCCATGTC

Downstream 100 bases:

>100_bases
CCTTTTGACGAACCTTTTGACTGGCCTCTTGACGGGCCATTTTCAGGGACACACCGCCGCTTGCAGCAGAAACCGAAGCA
GAAAATTCAGGACACGATAT

Product: Alpha,alpha-trehalose-phosphate synthase

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSRLVVVSNRVADPRKTAAGGLAVALGDALNATGGMWFGWSGTVIEGGAPGEGELHVQQAGNVKLATVDLSAEDHAGYYL
GYSNGVLWPVFHYRIDLARFDAGNIRAYRRVNQLFARKLMTQLRPDDIIWVHDYHLIPLAAELRAMGATQRIGFFLHIPL
PPQQVLAAIPQHEWLMRAMFAYDLLGFQSEADLQNFSHYVQAEAGAEDLGDNRFRAFNRTVRAGAFPIGIDVDEFAALTH
AKEGHDMYERMKDEYSRRKLLLGVERLDYSKGLPQRLRAFKSLLEKYPENIRSATLIQIASPSREDMGTYTDLLQELESL
CGAINGDFGELDWMPVRYMHRNVARKRLPGLYRVARVALVTPLRDGMNLVAKEFIAAQDPADPGVLVLSRFAGAAEQLKE
ALLVNPYDTDGTADTIQHALQMSLQERQGRHQRLLKNIREQDVHWWRKTFLDTLRDAGSD

Sequences:

>Translated_460_residues
MSRLVVVSNRVADPRKTAAGGLAVALGDALNATGGMWFGWSGTVIEGGAPGEGELHVQQAGNVKLATVDLSAEDHAGYYL
GYSNGVLWPVFHYRIDLARFDAGNIRAYRRVNQLFARKLMTQLRPDDIIWVHDYHLIPLAAELRAMGATQRIGFFLHIPL
PPQQVLAAIPQHEWLMRAMFAYDLLGFQSEADLQNFSHYVQAEAGAEDLGDNRFRAFNRTVRAGAFPIGIDVDEFAALTH
AKEGHDMYERMKDEYSRRKLLLGVERLDYSKGLPQRLRAFKSLLEKYPENIRSATLIQIASPSREDMGTYTDLLQELESL
CGAINGDFGELDWMPVRYMHRNVARKRLPGLYRVARVALVTPLRDGMNLVAKEFIAAQDPADPGVLVLSRFAGAAEQLKE
ALLVNPYDTDGTADTIQHALQMSLQERQGRHQRLLKNIREQDVHWWRKTFLDTLRDAGSD
>Mature_459_residues
SRLVVVSNRVADPRKTAAGGLAVALGDALNATGGMWFGWSGTVIEGGAPGEGELHVQQAGNVKLATVDLSAEDHAGYYLG
YSNGVLWPVFHYRIDLARFDAGNIRAYRRVNQLFARKLMTQLRPDDIIWVHDYHLIPLAAELRAMGATQRIGFFLHIPLP
PQQVLAAIPQHEWLMRAMFAYDLLGFQSEADLQNFSHYVQAEAGAEDLGDNRFRAFNRTVRAGAFPIGIDVDEFAALTHA
KEGHDMYERMKDEYSRRKLLLGVERLDYSKGLPQRLRAFKSLLEKYPENIRSATLIQIASPSREDMGTYTDLLQELESLC
GAINGDFGELDWMPVRYMHRNVARKRLPGLYRVARVALVTPLRDGMNLVAKEFIAAQDPADPGVLVLSRFAGAAEQLKEA
LLVNPYDTDGTADTIQHALQMSLQERQGRHQRLLKNIREQDVHWWRKTFLDTLRDAGSD

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=457, Percent_Identity=46.3894967177243, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71987012, Length=441, Percent_Identity=30.8390022675737, Blast_Score=182, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI115533558, Length=370, Percent_Identity=31.8918918918919, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI115533560, Length=370, Percent_Identity=31.8918918918919, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6319602, Length=470, Percent_Identity=33.6170212765957, Blast_Score=275, Evalue=9e-75,
Organism=Saccharomyces cerevisiae, GI6320279, Length=400, Percent_Identity=27.5, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6323917, Length=389, Percent_Identity=27.5064267352185, Blast_Score=172, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6323537, Length=382, Percent_Identity=29.0575916230367, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI19920676, Length=486, Percent_Identity=36.8312757201646, Blast_Score=295, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 51712; Mature: 51580

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLVVVSNRVADPRKTAAGGLAVALGDALNATGGMWFGWSGTVIEGGAPGEGELHVQQA
CCCEEEECCCCCCCHHHHCCCCEEEECCHHCCCCCEEECCCCCEEECCCCCCCCEEEEEC
GNVKLATVDLSAEDHAGYYLGYSNGVLWPVFHYRIDLARFDAGNIRAYRRVNQLFARKLM
CCEEEEEEEECCCCCCCEEEEECCCCEEEHHHHEEEHHCCCCCCHHHHHHHHHHHHHHHH
TQLRPDDIIWVHDYHLIPLAAELRAMGATQRIGFFLHIPLPPQQVLAAIPQHEWLMRAMF
HHCCCCCEEEEECCEECHHHHHHHHHCCHHHCCEEEECCCCHHHHHHHCCCHHHHHHHHH
AYDLLGFQSEADLQNFSHYVQAEAGAEDLGDNRFRAFNRTVRAGAFPIGIDVDEFAALTH
HHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHH
AKEGHDMYERMKDEYSRRKLLLGVERLDYSKGLPQRLRAFKSLLEKYPENIRSATLIQIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHCCEEEEEEC
SPSREDMGTYTDLLQELESLCGAINGDFGELDWMPVRYMHRNVARKRLPGLYRVARVALV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
TPLRDGMNLVAKEFIAAQDPADPGVLVLSRFAGAAEQLKEALLVNPYDTDGTADTIQHAL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
QMSLQERQGRHQRLLKNIREQDVHWWRKTFLDTLRDAGSD
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRLVVVSNRVADPRKTAAGGLAVALGDALNATGGMWFGWSGTVIEGGAPGEGELHVQQA
CCEEEECCCCCCCHHHHCCCCEEEECCHHCCCCCEEECCCCCEEECCCCCCCCEEEEEC
GNVKLATVDLSAEDHAGYYLGYSNGVLWPVFHYRIDLARFDAGNIRAYRRVNQLFARKLM
CCEEEEEEEECCCCCCCEEEEECCCCEEEHHHHEEEHHCCCCCCHHHHHHHHHHHHHHHH
TQLRPDDIIWVHDYHLIPLAAELRAMGATQRIGFFLHIPLPPQQVLAAIPQHEWLMRAMF
HHCCCCCEEEEECCEECHHHHHHHHHCCHHHCCEEEECCCCHHHHHHHCCCHHHHHHHHH
AYDLLGFQSEADLQNFSHYVQAEAGAEDLGDNRFRAFNRTVRAGAFPIGIDVDEFAALTH
HHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHH
AKEGHDMYERMKDEYSRRKLLLGVERLDYSKGLPQRLRAFKSLLEKYPENIRSATLIQIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHCCEEEEEEC
SPSREDMGTYTDLLQELESLCGAINGDFGELDWMPVRYMHRNVARKRLPGLYRVARVALV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
TPLRDGMNLVAKEFIAAQDPADPGVLVLSRFAGAAEQLKEALLVNPYDTDGTADTIQHAL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
QMSLQERQGRHQRLLKNIREQDVHWWRKTFLDTLRDAGSD
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA