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The map label for this gene is degP [C]

Identifier: 91789732

GI number: 91789732

Start: 4083286

End: 4084239

Strand: Direct

Name: degP [C]

Synonym: Bpro_3890

Alternate gene names: 91789732

Gene position: 4083286-4084239 (Clockwise)

Preceding gene: 91789731

Following gene: 91789733

Centisome position: 78.52

GC content: 64.36

Gene sequence:

>954_bases
ATGCGAAGGCCTGCCCTCTACAGTAGCTCCAGCCACGACCGCCGCGGCAACGACGCTCCGGATGCACCCGAGGCCGACCC
GCCTGCGCAGTCCCCGCCCCAGGAACTGCCGCTACCGGCACGCACTTCACGTTTTTCACGCCTGGCCGCGCGCTTTCCGG
CCTACAACCTCTACCTGCTCTGGTCCGTCATTGCCCTGTTGGCCCTGTTGCTGGCCATCAGTTTTTCCCTGTCACTGCAC
CCGCCGGGCCGCAAACTGACCCAGCACGACATCAACGCAGCCGTCCTCAAGACACTGGAGACGACCACCCTGCCCTCAGC
CGCCGCCAAGGCCTATCAGGTGATCAGCCCTTCCGTGGTGCGCGTCGTGGGCCAGGGCCGGGAAAAGGATGGCAAGGACG
GCAGCAAGGAAGAAGGCGAGCGCAGCGTGGGCACCGGCGTGGTCATCGTGGACAAGGGCATCATCCTGACCAACCTGCAT
GTGGTGCAGGGGGCAGAGAACATCAAGGTCACGTTCTCCGACGGCCTGGAGTCCACCGCCTCGATTGTCGGCATACAGCT
GGAAAACGATCTGGCGGTGTTGCAGGCCGACAAAATTCCGGACGACATGATCGCCGCCACCATGCGCTCCACGGCCGACC
TCGCGCCGGGCGATGAGGTGATGGCGGTGGGCTATCCGTTCGGCATCGGCCCTTCCGCTTCGGCCGGTGTCATCTCGGGG
CTCAAGCGCACCTTCCGCTCGCCCGAGGGCAAGCAGCAAATGACCAACCTCATCCAGTTCGACGCGGCCGCCAACCCGGG
TAATTCGGGTGGGCCACTGGTCACCATGGATGGCGAAGTCATCGGCATCGTGACCGCCATCTACAACCCCAACCAGCAAC
GCACGTTTGTCGGCATCGGCTTTGCCGTGCCGATTGAAAACGCGGCCTCGGCTGCCGGCATGCCCCCATTTTGA

Upstream 100 bases:

>100_bases
GAACGCAAAAATCGTGATACGGTGCAGTTCTTGAACCCGCAGTTTTTGAGCTTTTTTTGAGTGTGTTGAGCGTTTAGACA
TTTACCTCACAGGTGAACGG

Downstream 100 bases:

>100_bases
AAGACCCGAATGGAATCGCACACCCCTGATCATTTGCCTGTGAGCCACTTGCCCGTGAGCCACGAAACCGCCCAGTTGAT
GGAGCAAATCCTCTATGAGG

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MRRPALYSSSSHDRRGNDAPDAPEADPPAQSPPQELPLPARTSRFSRLAARFPAYNLYLLWSVIALLALLLAISFSLSLH
PPGRKLTQHDINAAVLKTLETTTLPSAAAKAYQVISPSVVRVVGQGREKDGKDGSKEEGERSVGTGVVIVDKGIILTNLH
VVQGAENIKVTFSDGLESTASIVGIQLENDLAVLQADKIPDDMIAATMRSTADLAPGDEVMAVGYPFGIGPSASAGVISG
LKRTFRSPEGKQQMTNLIQFDAAANPGNSGGPLVTMDGEVIGIVTAIYNPNQQRTFVGIGFAVPIENAASAAGMPPF

Sequences:

>Translated_317_residues
MRRPALYSSSSHDRRGNDAPDAPEADPPAQSPPQELPLPARTSRFSRLAARFPAYNLYLLWSVIALLALLLAISFSLSLH
PPGRKLTQHDINAAVLKTLETTTLPSAAAKAYQVISPSVVRVVGQGREKDGKDGSKEEGERSVGTGVVIVDKGIILTNLH
VVQGAENIKVTFSDGLESTASIVGIQLENDLAVLQADKIPDDMIAATMRSTADLAPGDEVMAVGYPFGIGPSASAGVISG
LKRTFRSPEGKQQMTNLIQFDAAANPGNSGGPLVTMDGEVIGIVTAIYNPNQQRTFVGIGFAVPIENAASAAGMPPF
>Mature_317_residues
MRRPALYSSSSHDRRGNDAPDAPEADPPAQSPPQELPLPARTSRFSRLAARFPAYNLYLLWSVIALLALLLAISFSLSLH
PPGRKLTQHDINAAVLKTLETTTLPSAAAKAYQVISPSVVRVVGQGREKDGKDGSKEEGERSVGTGVVIVDKGIILTNLH
VVQGAENIKVTFSDGLESTASIVGIQLENDLAVLQADKIPDDMIAATMRSTADLAPGDEVMAVGYPFGIGPSASAGVISG
LKRTFRSPEGKQQMTNLIQFDAAANPGNSGGPLVTMDGEVIGIVTAIYNPNQQRTFVGIGFAVPIENAASAAGMPPF

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=200, Percent_Identity=35, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4506141, Length=173, Percent_Identity=34.1040462427746, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI22129776, Length=172, Percent_Identity=35.4651162790698, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI7019477, Length=163, Percent_Identity=33.7423312883436, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1786356, Length=164, Percent_Identity=43.2926829268293, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789629, Length=163, Percent_Identity=41.7177914110429, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789630, Length=210, Percent_Identity=36.6666666666667, Blast_Score=99, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24646839, Length=167, Percent_Identity=35.3293413173653, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 33350; Mature: 33350

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPALYSSSSHDRRGNDAPDAPEADPPAQSPPQELPLPARTSRFSRLAARFPAYNLYLL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCHHHHH
WSVIALLALLLAISFSLSLHPPGRKLTQHDINAAVLKTLETTTLPSAAAKAYQVISPSVV
HHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHH
RVVGQGREKDGKDGSKEEGERSVGTGVVIVDKGIILTNLHVVQGAENIKVTFSDGLESTA
HHHCCCCCCCCCCCCHHHCCHHHCCCEEEEECCEEEEEEEEEECCCCEEEEECCCCCCCE
SIVGIQLENDLAVLQADKIPDDMIAATMRSTADLAPGDEVMAVGYPFGIGPSASAGVISG
EEEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHH
LKRTFRSPEGKQQMTNLIQFDAAANPGNSGGPLVTMDGEVIGIVTAIYNPNQQRTFVGIG
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEEEEECCCCCEEEEEEE
FAVPIENAASAAGMPPF
EEECCCCCHHCCCCCCC
>Mature Secondary Structure
MRRPALYSSSSHDRRGNDAPDAPEADPPAQSPPQELPLPARTSRFSRLAARFPAYNLYLL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCHHHHH
WSVIALLALLLAISFSLSLHPPGRKLTQHDINAAVLKTLETTTLPSAAAKAYQVISPSVV
HHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHH
RVVGQGREKDGKDGSKEEGERSVGTGVVIVDKGIILTNLHVVQGAENIKVTFSDGLESTA
HHHCCCCCCCCCCCCHHHCCHHHCCCEEEEECCEEEEEEEEEECCCCEEEEECCCCCCCE
SIVGIQLENDLAVLQADKIPDDMIAATMRSTADLAPGDEVMAVGYPFGIGPSASAGVISG
EEEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHH
LKRTFRSPEGKQQMTNLIQFDAAANPGNSGGPLVTMDGEVIGIVTAIYNPNQQRTFVGIG
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEEEEECCCCCEEEEEEE
FAVPIENAASAAGMPPF
EEECCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]