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The map label for this gene is fabG [H]

Identifier: 91789718

GI number: 91789718

Start: 4067408

End: 4068202

Strand: Reverse

Name: fabG [H]

Synonym: Bpro_3876

Alternate gene names: 91789718

Gene position: 4068202-4067408 (Counterclockwise)

Preceding gene: 91789719

Following gene: 91789717

Centisome position: 78.23

GC content: 64.15

Gene sequence:

>795_bases
ATGGATTTGGGTATTGCAGGCAAATGGGCGCTGGTCTGCGGCGCCAGCAAGGGTCTGGGCTTCGGTTGCGCGCAAGCGCT
GGTGCATGAAGGCGTGAACGTGCTCATCGTGGCGCGCGGCGCCGCGGCGCTGGAGGCCGCTGCTGACAAATTAATAGCTG
ACAACACCCGCCACGACAGCCCTGATGTGCAATTTGTTGCCGCAGACATCACCACACCCGAAGGCCGCGCCGCGGTTTTT
GCGGTGCGCAAGGATTTCGATATCGTGGTCACCAATGCCGGTGGTCCGCCACCGGGTGACTTCCGCGACTGGGACCGCGA
CGCCTGGATCAAGGCCGTCGATGCCAACATGCTGACGCCCATCGAATTGATCAAGGCCACGGTGGACGGCATGGCGGCGC
GCGGTTTTGGCCGCATCGTCAACATCACCTCCAGCGCCGTCAAGTCGCCCATCGATATCCTCGGCTTGTCCAACGGCGCC
CGCAGCGGCCTGACCGGTTTTGTTGCCGGCGTGGCGCGCAGCAAGCTGGCTGGGCAGGGCGTGACCATCAACAACCTGCT
GCCCGGCGCATTTGACACGGACCGGCTTCGGGGAACCATGAGCGGCGCGGCGCAGAAAACCGGCCAGCCGCTGGAAGCGA
TCATGGACGCGCGTCGCAAGAGCATTCCAGCCCAGCGTTTCGGAACGTCCGAAGAGTTTGGCGCCATCTGCGCATTTTTG
TGCAGCGCGCATGCGGGCTACATGACGGGCCAGAACGTGCTGGCCGACGGCGGCGCCTATCCGGGAACGTACTGA

Upstream 100 bases:

>100_bases
GGCCGCCAGAACCTGATTTCCCCGGCCCCCGAGATTCGACGCAACTCAGTATCATGGGCCATTCACTGATTCGCCAGTAA
CTTTCAAGCAAGGAACGATT

Downstream 100 bases:

>100_bases
AAAACGTACTGGAAACGTACTACAAACGAACGGTGCCAGGTGGCCTGCGGCGGGACGCCTGCCTCAAGCCGCGCCTGGCG
AACTCGTCCTACATGCGCTT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MDLGIAGKWALVCGASKGLGFGCAQALVHEGVNVLIVARGAAALEAAADKLIADNTRHDSPDVQFVAADITTPEGRAAVF
AVRKDFDIVVTNAGGPPPGDFRDWDRDAWIKAVDANMLTPIELIKATVDGMAARGFGRIVNITSSAVKSPIDILGLSNGA
RSGLTGFVAGVARSKLAGQGVTINNLLPGAFDTDRLRGTMSGAAQKTGQPLEAIMDARRKSIPAQRFGTSEEFGAICAFL
CSAHAGYMTGQNVLADGGAYPGTY

Sequences:

>Translated_264_residues
MDLGIAGKWALVCGASKGLGFGCAQALVHEGVNVLIVARGAAALEAAADKLIADNTRHDSPDVQFVAADITTPEGRAAVF
AVRKDFDIVVTNAGGPPPGDFRDWDRDAWIKAVDANMLTPIELIKATVDGMAARGFGRIVNITSSAVKSPIDILGLSNGA
RSGLTGFVAGVARSKLAGQGVTINNLLPGAFDTDRLRGTMSGAAQKTGQPLEAIMDARRKSIPAQRFGTSEEFGAICAFL
CSAHAGYMTGQNVLADGGAYPGTY
>Mature_264_residues
MDLGIAGKWALVCGASKGLGFGCAQALVHEGVNVLIVARGAAALEAAADKLIADNTRHDSPDVQFVAADITTPEGRAAVF
AVRKDFDIVVTNAGGPPPGDFRDWDRDAWIKAVDANMLTPIELIKATVDGMAARGFGRIVNITSSAVKSPIDILGLSNGA
RSGLTGFVAGVARSKLAGQGVTINNLLPGAFDTDRLRGTMSGAAQKTGQPLEAIMDARRKSIPAQRFGTSEEFGAICAFL
CSAHAGYMTGQNVLADGGAYPGTY

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=27.4131274131274, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=25.968992248062, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=25.968992248062, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI66933014, Length=202, Percent_Identity=28.7128712871287, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI226371731, Length=189, Percent_Identity=26.984126984127, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706318, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7705925, Length=264, Percent_Identity=26.1363636363636, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=268, Percent_Identity=29.8507462686567, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87082100, Length=268, Percent_Identity=31.7164179104478, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=27.6264591439689, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790717, Length=262, Percent_Identity=24.8091603053435, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082160, Length=266, Percent_Identity=24.812030075188, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787905, Length=261, Percent_Identity=24.904214559387, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=27.2030651340996, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=28.7878787878788, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=28.735632183908, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=28.3018867924528, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=26.7924528301887, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=273, Percent_Identity=26.3736263736264, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=27.6119402985075, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=27.0676691729323, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=26.7399267399267, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=27.3764258555133, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=25.9398496240602, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=26.4925373134328, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=25.7692307692308, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=273, Percent_Identity=26.3736263736264, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=29.3436293436293, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI23397609, Length=264, Percent_Identity=29.5454545454545, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27277; Mature: 27277

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIAGKWALVCGASKGLGFGCAQALVHEGVNVLIVARGAAALEAAADKLIADNTRHDS
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCC
PDVQFVAADITTPEGRAAVFAVRKDFDIVVTNAGGPPPGDFRDWDRDAWIKAVDANMLTP
CCEEEEEEECCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCHHHHEEECCCCCCCH
IELIKATVDGMAARGFGRIVNITSSAVKSPIDILGLSNGARSGLTGFVAGVARSKLAGQG
HHHHHHHHHHHHHHCCCCEEEECHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHHCCCC
VTINNLLPGAFDTDRLRGTMSGAAQKTGQPLEAIMDARRKSIPAQRFGTSEEFGAICAFL
EEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHH
CSAHAGYMTGQNVLADGGAYPGTY
HHCCCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MDLGIAGKWALVCGASKGLGFGCAQALVHEGVNVLIVARGAAALEAAADKLIADNTRHDS
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCC
PDVQFVAADITTPEGRAAVFAVRKDFDIVVTNAGGPPPGDFRDWDRDAWIKAVDANMLTP
CCEEEEEEECCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCHHHHEEECCCCCCCH
IELIKATVDGMAARGFGRIVNITSSAVKSPIDILGLSNGARSGLTGFVAGVARSKLAGQG
HHHHHHHHHHHHHHCCCCEEEECHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHHCCCC
VTINNLLPGAFDTDRLRGTMSGAAQKTGQPLEAIMDARRKSIPAQRFGTSEEFGAICAFL
EEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHH
CSAHAGYMTGQNVLADGGAYPGTY
HHCCCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]