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The map label for this gene is bdhA [H]

Identifier: 91789633

GI number: 91789633

Start: 3974561

End: 3975355

Strand: Direct

Name: bdhA [H]

Synonym: Bpro_3788

Alternate gene names: 91789633

Gene position: 3974561-3975355 (Clockwise)

Preceding gene: 91789630

Following gene: 91789635

Centisome position: 76.43

GC content: 63.27

Gene sequence:

>795_bases
ATGTCCAGCATACCCACAACGATTCTGGTGACAGGCGCGACCGGCGGCATAGGGCTCGCCGTCTGCCACAGGCTGGCGAG
AGCCGGCAACTCTCTCCTGCTTGCGGCGCGCGATGCCGACAAACTTCAGTCGCTGTGCGCGGACCTGTCCAGCGCCTCTT
CCGGCAGCCATTCATGGATTTCGGTGGACATGACGCGTGATGCGTCAGTCAGCGAATTCGCCGGGGAACTGGCCGCAAGG
AATGTGACGCTGGACGGAGCCGTATTGATGCCGCCACAGGACCCGCCCACCAGCGACCCGCTTCCCAGCAGCGACAAGTG
GCGCGAGGTTCTGCAGAACAGTTTTGTGGGCCCGCTGTCGCTGCTCAAGGTGGCTATCGCTGCCATGAAGCCGGACCCGG
CCAAGGGCAGGCGCGCCAAGATCGTCATCATCTCCGGCATCTCATCGGTGCAGGTAATGGGCCACTACGCCTCCAGCAAT
GTGATTCGCTGCGCCTGGCTGGCTGAAGCCAAGACGCTGGCGTTCGCGCTGGGCGACCGGGGAATCCATGTGAACACGCT
GTCCCTGGGGGGCACGCTCACGCCCGGGTACAGGGCCTCTCTGGAAAAGCGCGCAGCCAACGCCGGGACGACGTTTGAGC
AGCGCCTGGAGGAAGAGACATCAAATGTCCCCCTGCACAAATACGGCACGCCCGAAGAGGTGGCCGCTGCTGTCGAGGGA
CTGCTGTCGCCGTTCTCCGATCACATGACCGGGCTCAATATCCTGCACGATGGCGGATTCACGAGAGCCTATTGA

Upstream 100 bases:

>100_bases
GCCGCTGGCAGACAGGCCATAGCCTGAGGGTGCCTGGCGAGGTCAGGTGGTATCCGGCGGACATTCGGACTAGTATGGAG
CCTTCCCGAAGGAGTCGAGG

Downstream 100 bases:

>100_bases
GAAGAAAAAGGCGTTCCCTTTTCCCTTTTCCCTTTTCCCGCGCAGCGGAAGGGTCGCCCTGCTGCACGCTGCGCCTGCGG
CTCGCCTCAGGCCCGCAACC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSSIPTTILVTGATGGIGLAVCHRLARAGNSLLLAARDADKLQSLCADLSSASSGSHSWISVDMTRDASVSEFAGELAAR
NVTLDGAVLMPPQDPPTSDPLPSSDKWREVLQNSFVGPLSLLKVAIAAMKPDPAKGRRAKIVIISGISSVQVMGHYASSN
VIRCAWLAEAKTLAFALGDRGIHVNTLSLGGTLTPGYRASLEKRAANAGTTFEQRLEEETSNVPLHKYGTPEEVAAAVEG
LLSPFSDHMTGLNILHDGGFTRAY

Sequences:

>Translated_264_residues
MSSIPTTILVTGATGGIGLAVCHRLARAGNSLLLAARDADKLQSLCADLSSASSGSHSWISVDMTRDASVSEFAGELAAR
NVTLDGAVLMPPQDPPTSDPLPSSDKWREVLQNSFVGPLSLLKVAIAAMKPDPAKGRRAKIVIISGISSVQVMGHYASSN
VIRCAWLAEAKTLAFALGDRGIHVNTLSLGGTLTPGYRASLEKRAANAGTTFEQRLEEETSNVPLHKYGTPEEVAAAVEG
LLSPFSDHMTGLNILHDGGFTRAY
>Mature_263_residues
SSIPTTILVTGATGGIGLAVCHRLARAGNSLLLAARDADKLQSLCADLSSASSGSHSWISVDMTRDASVSEFAGELAARN
VTLDGAVLMPPQDPPTSDPLPSSDKWREVLQNSFVGPLSLLKVAIAAMKPDPAKGRRAKIVIISGISSVQVMGHYASSNV
IRCAWLAEAKTLAFALGDRGIHVNTLSLGGTLTPGYRASLEKRAANAGTTFEQRLEEETSNVPLHKYGTPEEVAAAVEGL
LSPFSDHMTGLNILHDGGFTRAY

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17508651, Length=257, Percent_Identity=25.2918287937743, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=25.7692307692308, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=25.7692307692308, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=23.8095238095238, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27721; Mature: 27590

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIPTTILVTGATGGIGLAVCHRLARAGNSLLLAARDADKLQSLCADLSSASSGSHSWI
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEE
SVDMTRDASVSEFAGELAARNVTLDGAVLMPPQDPPTSDPLPSSDKWREVLQNSFVGPLS
EEEECCCCCHHHHHHHHHHCEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHH
LLKVAIAAMKPDPAKGRRAKIVIISGISSVQVMGHYASSNVIRCAWLAEAKTLAFALGDR
HHHHHHHHCCCCCCCCCEEEEEEEECCCEEEHEEECCCCCEEEEEEHHHHHHEEEEECCC
GIHVNTLSLGGTLTPGYRASLEKRAANAGTTFEQRLEEETSNVPLHKYGTPEEVAAAVEG
CEEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
LLSPFSDHMTGLNILHDGGFTRAY
HHHHHHHHHCCCEEEECCCCCCCC
>Mature Secondary Structure 
SSIPTTILVTGATGGIGLAVCHRLARAGNSLLLAARDADKLQSLCADLSSASSGSHSWI
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEE
SVDMTRDASVSEFAGELAARNVTLDGAVLMPPQDPPTSDPLPSSDKWREVLQNSFVGPLS
EEEECCCCCHHHHHHHHHHCEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHH
LLKVAIAAMKPDPAKGRRAKIVIISGISSVQVMGHYASSNVIRCAWLAEAKTLAFALGDR
HHHHHHHHCCCCCCCCCEEEEEEEECCCEEEHEEECCCCCEEEEEEHHHHHHEEEEECCC
GIHVNTLSLGGTLTPGYRASLEKRAANAGTTFEQRLEEETSNVPLHKYGTPEEVAAAVEG
CEEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
LLSPFSDHMTGLNILHDGGFTRAY
HHHHHHHHHCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]