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The map label for this gene is dinB [H]

Identifier: 91789542

GI number: 91789542

Start: 3906981

End: 3908249

Strand: Direct

Name: dinB [H]

Synonym: Bpro_3696

Alternate gene names: 91789542

Gene position: 3906981-3908249 (Clockwise)

Preceding gene: 91789540

Following gene: 91789545

Centisome position: 75.13

GC content: 61.15

Gene sequence:

>1269_bases
GTGAACGTTTCAAGCCCGTCCCACAGCGCCAGACTGCGCCGTATTGCCCACCTCGACATGGATGCTTTTTTTGCGTCGAT
CGAGTTGCTGCGCTACCCGCAACTCAAAGGCCTGCCCGTGGTGATTGGTGGCGGGCGGCGCAAGGTGGATGAAGAACTGC
TGGCGGCGCAAGGCGAGCGCGCGCTGCGCTTCATTCCGGTGGAAAATTTTCCGCTGCTCAAGGACTATGTGGGCCGCGGC
GTGATCACCACGGCGACCTACGCAGCGCGGCAATTTGGCGTGGGCTCGGCCATGGGCATGATGAAGGCGGCCAAACTCTG
TCCGCAGGCCATTGTGTTGCCGGTCGATTTTGAAGAAGTGCGCAAATACTCGCGGCTGTTCAAAAGCACCATCACCGAGA
TTGCCCCCGTGATGCAGGACCGCGGGGTGGACGAGGTGTATATCGACTTCACCGATGTGCCCGGCGGCCAGCGCGAGGGA
GGCCGGGTGCTGGCGCGGTTGATCCAGAAAGCGATTTTTGAAAAGACCGGCCTCACCTGCTCGGTTGGCGTGGCCCCCAA
CAAGCTGCTGGCCAAGATGGCCAGCGAGTTCGACAAGCCCAATGGCATTTCGATTGTGTACGAGGAAGACCTGCAGCCCC
GGATCTGGCCGCTCAACGTACGCAAGATCAACGGCATTGGTCCCAAGGCCGGGGAAAAGCTGGCCAGGCTGCACATCCAC
ACCATCGGCGAGCTGGCCGCGCAGGATCCTTCATTTCTGATTGCCAATTTCGGCAAAGCCACGGGCGCCTGGATGCACGA
GGCCGCCTGGGGCCGTGACGACCGGCCAGTGGTCACCGAGAGCGAGCCCGTCAGCATGAGCCGGGAAACCACCTTTGACC
GCGACCTGCATGCAGTGCGCGACAAGGCGGTGCTTGGCGCCATCTTCACCGATCTGTGCAGCAAACTGGCGCAGGACCTG
CAGCGCAAGGGCTATGTGGCCAAAACCATAGGCATCAAGCTGCGCTATGACGATTTCAGAATTGCAACGCGCGACCAGAC
CGCCGACAGCTACACCGCTGACGGTCAAGCCATCCGGAAACTGGCGGGCCTGTGCCTGAAGCGGGTTCCGCTCGAGAAAA
AGCTGCGCTTGCTGGGCGTTCGCGCCAGCACGCTGGCCAAAGCCGGCGAAGAGCCGGTGCCCGAACAAAAATCGCCACCA
TCCCGATCGGGAAGCCCGCAACAAGGGCAACAAGGTATTGAATCGATGGCAAGCGATCAATTGTTCTAA

Upstream 100 bases:

>100_bases
CGGTCCCCCACACTCGCGCCCGCATCGGCGTGGAAGTCGGCATTCCGGATGCTTGACCACACAAAAGCGATGACACGTCG
ACGAGCGCTATGCTTGCCAT

Downstream 100 bases:

>100_bases
CGCATCGACCGCTCCACCATCAGCGCTAGCTATCACCCCCTTTCAGAAACGCCGCCCAGCGGTGCAAGGTCGGATAAATA
GACACGGTTGCCGAGCTGCA

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MNVSSPSHSARLRRIAHLDMDAFFASIELLRYPQLKGLPVVIGGGRRKVDEELLAAQGERALRFIPVENFPLLKDYVGRG
VITTATYAARQFGVGSAMGMMKAAKLCPQAIVLPVDFEEVRKYSRLFKSTITEIAPVMQDRGVDEVYIDFTDVPGGQREG
GRVLARLIQKAIFEKTGLTCSVGVAPNKLLAKMASEFDKPNGISIVYEEDLQPRIWPLNVRKINGIGPKAGEKLARLHIH
TIGELAAQDPSFLIANFGKATGAWMHEAAWGRDDRPVVTESEPVSMSRETTFDRDLHAVRDKAVLGAIFTDLCSKLAQDL
QRKGYVAKTIGIKLRYDDFRIATRDQTADSYTADGQAIRKLAGLCLKRVPLEKKLRLLGVRASTLAKAGEEPVPEQKSPP
SRSGSPQQGQQGIESMASDQLF

Sequences:

>Translated_422_residues
MNVSSPSHSARLRRIAHLDMDAFFASIELLRYPQLKGLPVVIGGGRRKVDEELLAAQGERALRFIPVENFPLLKDYVGRG
VITTATYAARQFGVGSAMGMMKAAKLCPQAIVLPVDFEEVRKYSRLFKSTITEIAPVMQDRGVDEVYIDFTDVPGGQREG
GRVLARLIQKAIFEKTGLTCSVGVAPNKLLAKMASEFDKPNGISIVYEEDLQPRIWPLNVRKINGIGPKAGEKLARLHIH
TIGELAAQDPSFLIANFGKATGAWMHEAAWGRDDRPVVTESEPVSMSRETTFDRDLHAVRDKAVLGAIFTDLCSKLAQDL
QRKGYVAKTIGIKLRYDDFRIATRDQTADSYTADGQAIRKLAGLCLKRVPLEKKLRLLGVRASTLAKAGEEPVPEQKSPP
SRSGSPQQGQQGIESMASDQLF
>Mature_422_residues
MNVSSPSHSARLRRIAHLDMDAFFASIELLRYPQLKGLPVVIGGGRRKVDEELLAAQGERALRFIPVENFPLLKDYVGRG
VITTATYAARQFGVGSAMGMMKAAKLCPQAIVLPVDFEEVRKYSRLFKSTITEIAPVMQDRGVDEVYIDFTDVPGGQREG
GRVLARLIQKAIFEKTGLTCSVGVAPNKLLAKMASEFDKPNGISIVYEEDLQPRIWPLNVRKINGIGPKAGEKLARLHIH
TIGELAAQDPSFLIANFGKATGAWMHEAAWGRDDRPVVTESEPVSMSRETTFDRDLHAVRDKAVLGAIFTDLCSKLAQDL
QRKGYVAKTIGIKLRYDDFRIATRDQTADSYTADGQAIRKLAGLCLKRVPLEKKLRLLGVRASTLAKAGEEPVPEQKSPP
SRSGSPQQGQQGIESMASDQLF

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=362, Percent_Identity=26.2430939226519, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI84043967, Length=311, Percent_Identity=28.2958199356913, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI7706681, Length=313, Percent_Identity=27.7955271565495, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI7705344, Length=251, Percent_Identity=32.2709163346614, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI5729982, Length=402, Percent_Identity=23.6318407960199, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1786425, Length=337, Percent_Identity=31.4540059347181, Blast_Score=160, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI193205700, Length=436, Percent_Identity=24.3119266055046, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193205702, Length=342, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17537959, Length=270, Percent_Identity=23.7037037037037, Blast_Score=75, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=286, Percent_Identity=26.2237762237762, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19923006, Length=354, Percent_Identity=25.1412429378531, Blast_Score=125, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 46429; Mature: 46429

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSSPSHSARLRRIAHLDMDAFFASIELLRYPQLKGLPVVIGGGRRKVDEELLAAQGER
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCC
ALRFIPVENFPLLKDYVGRGVITTATYAARQFGVGSAMGMMKAAKLCPQAIVLPVDFEEV
CEEEEECCCCCHHHHHHCCCEEHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCHHHH
RKYSRLFKSTITEIAPVMQDRGVDEVYIDFTDVPGGQREGGRVLARLIQKAIFEKTGLTC
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEE
SVGVAPNKLLAKMASEFDKPNGISIVYEEDLQPRIWPLNVRKINGIGPKAGEKLARLHIH
EECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHH
TIGELAAQDPSFLIANFGKATGAWMHEAAWGRDDRPVVTESEPVSMSRETTFDRDLHAVR
HHHHHHCCCCCEEEHHCCCHHHHHHHHHHCCCCCCCCEECCCCCCCCHHCCHHHHHHHHH
DKAVLGAIFTDLCSKLAQDLQRKGYVAKTIGIKLRYDDFRIATRDQTADSYTADGQAIRK
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCEEEEECCCCCCCCCCCHHHHHH
LAGLCLKRVPLEKKLRLLGVRASTLAKAGEEPVPEQKSPPSRSGSPQQGQQGIESMASDQ
HHHHHHHHCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LF
CC
>Mature Secondary Structure
MNVSSPSHSARLRRIAHLDMDAFFASIELLRYPQLKGLPVVIGGGRRKVDEELLAAQGER
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCC
ALRFIPVENFPLLKDYVGRGVITTATYAARQFGVGSAMGMMKAAKLCPQAIVLPVDFEEV
CEEEEECCCCCHHHHHHCCCEEHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCHHHH
RKYSRLFKSTITEIAPVMQDRGVDEVYIDFTDVPGGQREGGRVLARLIQKAIFEKTGLTC
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEE
SVGVAPNKLLAKMASEFDKPNGISIVYEEDLQPRIWPLNVRKINGIGPKAGEKLARLHIH
EECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHH
TIGELAAQDPSFLIANFGKATGAWMHEAAWGRDDRPVVTESEPVSMSRETTFDRDLHAVR
HHHHHHCCCCCEEEHHCCCHHHHHHHHHHCCCCCCCCEECCCCCCCCHHCCHHHHHHHHH
DKAVLGAIFTDLCSKLAQDLQRKGYVAKTIGIKLRYDDFRIATRDQTADSYTADGQAIRK
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCEEEEECCCCCCCCCCCHHHHHH
LAGLCLKRVPLEKKLRLLGVRASTLAKAGEEPVPEQKSPPSRSGSPQQGQQGIESMASDQ
HHHHHHHHCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LF
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]