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The map label for this gene is fabD [H]

Identifier: 91789498

GI number: 91789498

Start: 3848285

End: 3849295

Strand: Reverse

Name: fabD [H]

Synonym: Bpro_3648

Alternate gene names: 91789498

Gene position: 3849295-3848285 (Counterclockwise)

Preceding gene: 91789499

Following gene: 91789497

Centisome position: 74.02

GC content: 63.2

Gene sequence:

>1011_bases
ATGGGTTTCTTAGAATGGCGGGCGCTGACAGGTTCGCCGCTTGATAACTGGAGTAATTATTTGAAATCGTTCGCTGTTGT
TTTTCCCGGCCAGGGTTCGCAGTCGGTGGGCATGCTGGACGCCTGGGGCGACCATGCTGTTGTCCGGCAAACACTCCTGG
AAGCTTCTGATGCCTTGGGGCAGGACGTCGGCCAGCTGATCAAGAACGGGCCCAAAGAGACCCTCGCTCTGACGACCAAT
ACCCAGCCGGTGATGCTGGTGGCGGGTGTGGCTGCCTACCGGGCGTGGATCGCGGAAACCGGCGCGGCGCCAGCTGCCGT
GGCTGGCCATTCGCTGGGCGAGTATTCGGCGCTGGTGGCCGCGGGGGTGTTGTCGCTGGCGCAAGCCGCCCCGCTGGTGC
GCTTTCGGGCCCAGGCCATGCAGGATGCCGTGCCCGTGGGGGTGGGCGCGATGGCGGCCATCCTGGGCATGGACGCGGCC
CGGGTCATTGAGGGTTGTGCCGAGGCAGTCCGCACCTTTGGACCCAATACCGATGAGGTTGTGGAAGCCGTCAATTTCAA
CGACCCCCTGCAGACCGTCATTGCGGGCAGCAAGGCTGCGGTGGACAAGGCTTGCGAAGTGCTCAAAGCCAACGGCGCGA
AGCGGGCCTTGCCGCTGCCGGTGTCGGCGCCGTTTCATTCGAGCCTGATGAAACCGGCCGCCGAGAAGCTCAGGGAAAAA
CTCGCTGCCGTCGATTTCGCGGTTCCGCAGATTCCCGTCATCAACAATATAGAAGTGGCGGTGGAGACGGATGCCGATCG
CATTCGTGCGGCGCTTTATGAACAGGCGTTCGGACCGGTACGCTGGGTGGAGTGTGTCCAGGCCATCAAGGCGCGGGGGC
TCACGACCATCGTCGAGTGCGGGCCGGGCAAGGTGCTGACCGGCATGGTCAAAAGGATAGACCCGGAATTGACGGGCGCG
CCCCTGTTTGATCCGGCCTCGATGGCAGATGTGAAGGAGATGCTGGCATGA

Upstream 100 bases:

>100_bases
CCACCGCAGCAGCGTTCACTTGACTGCCGTTTCCGCTTCGAAAATCGCGGGCCGCATGGCGGCGGGTGGGGTGGGGCTTG
CCTGATCGGTTGCCGTCCCG

Downstream 100 bases:

>100_bases
ATGAAGTCAAGTTTGAGGGGCAGGTTGCGCTGGTCACCGGTGCATCGCGCGGCATAGGCGCTGCCATCGCGCTGGAGCTG
GCCCAGAAGGGCCTGAAGGT

Product: [acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MGFLEWRALTGSPLDNWSNYLKSFAVVFPGQGSQSVGMLDAWGDHAVVRQTLLEASDALGQDVGQLIKNGPKETLALTTN
TQPVMLVAGVAAYRAWIAETGAAPAAVAGHSLGEYSALVAAGVLSLAQAAPLVRFRAQAMQDAVPVGVGAMAAILGMDAA
RVIEGCAEAVRTFGPNTDEVVEAVNFNDPLQTVIAGSKAAVDKACEVLKANGAKRALPLPVSAPFHSSLMKPAAEKLREK
LAAVDFAVPQIPVINNIEVAVETDADRIRAALYEQAFGPVRWVECVQAIKARGLTTIVECGPGKVLTGMVKRIDPELTGA
PLFDPASMADVKEMLA

Sequences:

>Translated_336_residues
MGFLEWRALTGSPLDNWSNYLKSFAVVFPGQGSQSVGMLDAWGDHAVVRQTLLEASDALGQDVGQLIKNGPKETLALTTN
TQPVMLVAGVAAYRAWIAETGAAPAAVAGHSLGEYSALVAAGVLSLAQAAPLVRFRAQAMQDAVPVGVGAMAAILGMDAA
RVIEGCAEAVRTFGPNTDEVVEAVNFNDPLQTVIAGSKAAVDKACEVLKANGAKRALPLPVSAPFHSSLMKPAAEKLREK
LAAVDFAVPQIPVINNIEVAVETDADRIRAALYEQAFGPVRWVECVQAIKARGLTTIVECGPGKVLTGMVKRIDPELTGA
PLFDPASMADVKEMLA
>Mature_335_residues
GFLEWRALTGSPLDNWSNYLKSFAVVFPGQGSQSVGMLDAWGDHAVVRQTLLEASDALGQDVGQLIKNGPKETLALTTNT
QPVMLVAGVAAYRAWIAETGAAPAAVAGHSLGEYSALVAAGVLSLAQAAPLVRFRAQAMQDAVPVGVGAMAAILGMDAAR
VIEGCAEAVRTFGPNTDEVVEAVNFNDPLQTVIAGSKAAVDKACEVLKANGAKRALPLPVSAPFHSSLMKPAAEKLREKL
AAVDFAVPQIPVINNIEVAVETDADRIRAALYEQAFGPVRWVECVQAIKARGLTTIVECGPGKVLTGMVKRIDPELTGAP
LFDPASMADVKEMLA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=303, Percent_Identity=33.993399339934, Blast_Score=146, Evalue=3e-35,
Organism=Escherichia coli, GI1787334, Length=315, Percent_Identity=51.7460317460318, Blast_Score=286, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI71984332, Length=290, Percent_Identity=30, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=297, Percent_Identity=28.956228956229, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=31.5614617940199, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 35167; Mature: 35036

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFLEWRALTGSPLDNWSNYLKSFAVVFPGQGSQSVGMLDAWGDHAVVRQTLLEASDALG
CCCCEEECCCCCCHHHHHHHHHHHHEEECCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHH
QDVGQLIKNGPKETLALTTNTQPVMLVAGVAAYRAWIAETGAAPAAVAGHSLGEYSALVA
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHH
AGVLSLAQAAPLVRFRAQAMQDAVPVGVGAMAAILGMDAARVIEGCAEAVRTFGPNTDEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
VEAVNFNDPLQTVIAGSKAAVDKACEVLKANGAKRALPLPVSAPFHSSLMKPAAEKLREK
HHHHCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LAAVDFAVPQIPVINNIEVAVETDADRIRAALYEQAFGPVRWVECVQAIKARGLTTIVEC
HHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEC
GPGKVLTGMVKRIDPELTGAPLFDPASMADVKEMLA
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHC
>Mature Secondary Structure 
GFLEWRALTGSPLDNWSNYLKSFAVVFPGQGSQSVGMLDAWGDHAVVRQTLLEASDALG
CCCEEECCCCCCHHHHHHHHHHHHEEECCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHH
QDVGQLIKNGPKETLALTTNTQPVMLVAGVAAYRAWIAETGAAPAAVAGHSLGEYSALVA
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHH
AGVLSLAQAAPLVRFRAQAMQDAVPVGVGAMAAILGMDAARVIEGCAEAVRTFGPNTDEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
VEAVNFNDPLQTVIAGSKAAVDKACEVLKANGAKRALPLPVSAPFHSSLMKPAAEKLREK
HHHHCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LAAVDFAVPQIPVINNIEVAVETDADRIRAALYEQAFGPVRWVECVQAIKARGLTTIVEC
HHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEC
GPGKVLTGMVKRIDPELTGAPLFDPASMADVKEMLA
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]