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The map label for this gene is iorA [H]

Identifier: 91789411

GI number: 91789411

Start: 3757606

End: 3758064

Strand: Reverse

Name: iorA [H]

Synonym: Bpro_3557

Alternate gene names: 91789411

Gene position: 3758064-3757606 (Counterclockwise)

Preceding gene: 91789412

Following gene: 91789410

Centisome position: 72.27

GC content: 66.23

Gene sequence:

>459_bases
ATGCCCACCCTCAACATCAATGGCAAGGACACGCCCGTCAATGCCGACGAATCCACCCCCATCCTCTGGGCCCTGCGTGA
CACGCTGGGCATGACAGGCACCAAGTTCGGCTGCGGCGCGGCGCTGTGCGGCGCCTGCACCGTGCACCTCAACGGCGCGG
CCATCCGCTCCTGCGTGACGCCGATATCGGCTGCCGTGGGCCAGAAAATTACCACCATCGAAGCCGTGGCTTCCGATCGG
GTAGGCAAGGCCGTCCAGGACGCCTGGGTCAAGCACGACGTGGCGCAATGCGGTTATTGCCAGAGCGGCCAGGTGATGAG
CGCCACCGCCCTGCTCAAGGCCAAGGCCAAGCCAACCAACGCAGACATCGACGCCGCCATGGCCGGCAACATCTGCCGCT
GCGGCACCTATGTGCGCATTCGCGCCGCCATCAAAGACGCCGCCCTGGCCCTGGCCTGA

Upstream 100 bases:

>100_bases
GTTTTTTTGATAAAACCCGAATTTAAGCGAATATAAATTCGTCAAGTAGTCCCCCCAGCAATTCCATTCCCCAGTTTTGC
CCCCCGCAAGGAGCTCCACG

Downstream 100 bases:

>100_bases
AGGAGAACACCATGTATTCCAACTCAACAGACACCCTGGACATCACCGGGCAATTGCCAAAAGGCCTGCAGGCCCTGATG
CACAAAGCACAAGAGGGTAC

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MPTLNINGKDTPVNADESTPILWALRDTLGMTGTKFGCGAALCGACTVHLNGAAIRSCVTPISAAVGQKITTIEAVASDR
VGKAVQDAWVKHDVAQCGYCQSGQVMSATALLKAKAKPTNADIDAAMAGNICRCGTYVRIRAAIKDAALALA

Sequences:

>Translated_152_residues
MPTLNINGKDTPVNADESTPILWALRDTLGMTGTKFGCGAALCGACTVHLNGAAIRSCVTPISAAVGQKITTIEAVASDR
VGKAVQDAWVKHDVAQCGYCQSGQVMSATALLKAKAKPTNADIDAAMAGNICRCGTYVRIRAAIKDAALALA
>Mature_151_residues
PTLNINGKDTPVNADESTPILWALRDTLGMTGTKFGCGAALCGACTVHLNGAAIRSCVTPISAAVGQKITTIEAVASDRV
GKAVQDAWVKHDVAQCGYCQSGQVMSATALLKAKAKPTNADIDAAMAGNICRCGTYVRIRAAIKDAALALA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=144, Percent_Identity=37.5, Blast_Score=74, Evalue=4e-14,
Organism=Homo sapiens, GI71773480, Length=90, Percent_Identity=36.6666666666667, Blast_Score=63, Evalue=9e-11,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=44.5121951219512, Blast_Score=122, Evalue=8e-30,
Organism=Escherichia coli, GI1789232, Length=144, Percent_Identity=38.8888888888889, Blast_Score=91, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=152, Percent_Identity=37.5, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=156, Percent_Identity=36.5384615384615, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32566215, Length=152, Percent_Identity=36.8421052631579, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17737937, Length=144, Percent_Identity=36.8055555555556, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647193, Length=163, Percent_Identity=36.8098159509202, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=31.6129032258064, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647201, Length=156, Percent_Identity=28.8461538461538, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647197, Length=161, Percent_Identity=29.1925465838509, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647195, Length=161, Percent_Identity=29.1925465838509, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15606; Mature: 15475

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLNINGKDTPVNADESTPILWALRDTLGMTGTKFGCGAALCGACTVHLNGAAIRSCVT
CCCCCCCCCCCCCCCCCCCCEEEEEHHHHCCCCCCCCCHHHHHHEEEEEECHHHHHHHHH
PISAAVGQKITTIEAVASDRVGKAVQDAWVKHDVAQCGYCQSGQVMSATALLKAKAKPTN
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCCCC
ADIDAAMAGNICRCGTYVRIRAAIKDAALALA
CCCCHHHCCCEECCCCEEEEHHHHHHHHHHCC
>Mature Secondary Structure 
PTLNINGKDTPVNADESTPILWALRDTLGMTGTKFGCGAALCGACTVHLNGAAIRSCVT
CCCCCCCCCCCCCCCCCCCEEEEEHHHHCCCCCCCCCHHHHHHEEEEEECHHHHHHHHH
PISAAVGQKITTIEAVASDRVGKAVQDAWVKHDVAQCGYCQSGQVMSATALLKAKAKPTN
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCCCC
ADIDAAMAGNICRCGTYVRIRAAIKDAALALA
CCCCHHHCCCEECCCCEEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]