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The map label for this gene is edd [H]

Identifier: 91789405

GI number: 91789405

Start: 3750633

End: 3752450

Strand: Reverse

Name: edd [H]

Synonym: Bpro_3551

Alternate gene names: 91789405

Gene position: 3752450-3750633 (Counterclockwise)

Preceding gene: 91789406

Following gene: 91789404

Centisome position: 72.16

GC content: 66.12

Gene sequence:

>1818_bases
ATGGCTCTTCATCCCGCAATCTCACACATCACGGCCCGTATTGCCGAGCGCAGCCGTCCCACACGCGGCGCCTACCTGCA
GCAGCTGCAGGTGGCGGCCCGGCGTGATCCAGGCGTCGACCGCATGGGTTGCGCCAACGTGGCCCACGCGGTGGCTGGCA
TTCCGCTCGACGACCGTTTCAAGGTCATCACCCACAAGGCGCCCAACATCGGCATCGTCAATGCCTACAACGACATGCTG
TCGGCGCATGTGCCCCTGCAGGGCTACCCGGCCCTGATCAAGGACGAGGCGCGCAAGCTGGGCGCGACGGCGCAGGTAGC
CGGTGGCGTACCCGCCATGTGCGACGGCGTCACGCAGGGCACGCCCGGCATGGAGCTCAGCCTGTTCAGCCGCGACGTGA
TTGCCATGGCCACCGCCGTGGCGCTCTCACACGACATGTTCGACGCGGCGCTGATGCTCGGCGTGTGCGACAAGATCGTG
CCGGGCCTGCTGATCGGTGCGCTCCACTTTGGTCACTTGCCCACCGTGTTTGTACCGGCGGGCCCGATGACCACGGGCTT
GCCCAACAAGGAAAAAGCCCGCGTGCGCGAGCAGGCGGCGCAGGGGCTGGTCGGGCGCGAGGGCTTGCTCGATGCCGAAC
TCAAGTCCTACCACAGCCCCGGCACCTGCACGTTTTACGGCACGGCCAACAGCAACCAGCTGCTGCTCGAAGCCATGGGC
CTGCACGTGCCCGGTACCGCCTTCGTCAACCCCGGTAATGAGTTGCGCGAGCAGCTCACCCGCGAGGCGGCGCGCACGGT
GCTGGGAATCACCAAGTCCAAACGCTTTGCGCCCATCGGCCAGATCGTCGACGAACGGGCCATCGTCAACGCCATGGTGG
CCCTGCTCGCCACGGGCGGCTCCACCAACCACCTGATTCACTGGGTCGCGGTGGCCCACTCGGCCGGAATCGTGATTGAC
TGGAATGATTTTTCCGACTTGTCCGATGTGGTGCCGACGCTGGCGCATGTCTACCCCAACGGCAGTGCCGACGTGAACCA
GTTCCAGGCGGCAGGCGGCCCCGGGCTGATCATTCGCGAACTGCTGGACGCCGGCCTGATGCATGAGGATGTGCTGACGG
TGCGCGAGGGCGGCATCCGCGAATACACGCGTGAACCGGCGTTGGCCGGGGCTTCGCTGGCCTGGCATGAAATCGGCGCT
TCGAAAGATGAGTCGATTGTGCGTTCTGCCGGCAAGCCTTTCAGCCCCAGCGGCGGGCTCAAGTTGCTGCAGGGCAACCT
GGGCCGCAGTGTGATCAAGGTCTCCGCCGTGCCCGATGACCGGCATGTGATAGAAGCGCCCGCCCGCGTGTTCGATTCGC
AGGAAGCCTTGCACGCCGCCTTCAATGCCAAGGAGCTGGACCGCGACATGGTGTGCGTGGTGCGCTGGCAAGGGCCGCAG
GCCAATGGCATGCCGGAATTGCACAAGCTCACGCCGCCGCTGGCGGTGCTGCAGGGCAAGGGGTTCCGGGTGGCACTGGT
CACCGATGGCCGCATGAGTGGCGCGTCGGGCAAGGTGCCGGCGGCCATCCACGTGTCGCCCGAGGCCGCTGCGGGCGGAC
CGCTGGCCAAGGTGCGTGACGGCGACATGATCCGGCTCGATGCCGTCACGGGCGAGTTGCAGGTTCTCGTGCCTGAAGCA
GAATGGGTGGCACGGCAGGTTGACACCATGCCGCCCGCCTTGCGACGGGACAACGGCATTGGCCTGGGCCGCGAATTGTT
TACCGGCATGCGCCGCCATGCCCTGACGGCAGAAGAAGGAGCTTTATCGTGGATGTAA

Upstream 100 bases:

>100_bases
CCTGTTTTGGTAACCATACGGTAACCCGGGGGTGTCAAAAGCGTCGGTAACCCGTTACCATAGAGTCCGTAATAAAGTTA
CATGATCTAAGGTGCAACGC

Downstream 100 bases:

>100_bases
ATCTGGATGTCAGTGGCAAGCTGACGGCCTTGCAGGTCATGCGGGATGCGCCCGTGATTCCCGTGATTGTGCTGACCGAC
GTCAATAAGGCGGTTCTACT

Product: phosphogluconate dehydratase

Products: NA

Alternate protein names: 6-phosphogluconate dehydratase [H]

Number of amino acids: Translated: 605; Mature: 604

Protein sequence:

>605_residues
MALHPAISHITARIAERSRPTRGAYLQQLQVAARRDPGVDRMGCANVAHAVAGIPLDDRFKVITHKAPNIGIVNAYNDML
SAHVPLQGYPALIKDEARKLGATAQVAGGVPAMCDGVTQGTPGMELSLFSRDVIAMATAVALSHDMFDAALMLGVCDKIV
PGLLIGALHFGHLPTVFVPAGPMTTGLPNKEKARVREQAAQGLVGREGLLDAELKSYHSPGTCTFYGTANSNQLLLEAMG
LHVPGTAFVNPGNELREQLTREAARTVLGITKSKRFAPIGQIVDERAIVNAMVALLATGGSTNHLIHWVAVAHSAGIVID
WNDFSDLSDVVPTLAHVYPNGSADVNQFQAAGGPGLIIRELLDAGLMHEDVLTVREGGIREYTREPALAGASLAWHEIGA
SKDESIVRSAGKPFSPSGGLKLLQGNLGRSVIKVSAVPDDRHVIEAPARVFDSQEALHAAFNAKELDRDMVCVVRWQGPQ
ANGMPELHKLTPPLAVLQGKGFRVALVTDGRMSGASGKVPAAIHVSPEAAAGGPLAKVRDGDMIRLDAVTGELQVLVPEA
EWVARQVDTMPPALRRDNGIGLGRELFTGMRRHALTAEEGALSWM

Sequences:

>Translated_605_residues
MALHPAISHITARIAERSRPTRGAYLQQLQVAARRDPGVDRMGCANVAHAVAGIPLDDRFKVITHKAPNIGIVNAYNDML
SAHVPLQGYPALIKDEARKLGATAQVAGGVPAMCDGVTQGTPGMELSLFSRDVIAMATAVALSHDMFDAALMLGVCDKIV
PGLLIGALHFGHLPTVFVPAGPMTTGLPNKEKARVREQAAQGLVGREGLLDAELKSYHSPGTCTFYGTANSNQLLLEAMG
LHVPGTAFVNPGNELREQLTREAARTVLGITKSKRFAPIGQIVDERAIVNAMVALLATGGSTNHLIHWVAVAHSAGIVID
WNDFSDLSDVVPTLAHVYPNGSADVNQFQAAGGPGLIIRELLDAGLMHEDVLTVREGGIREYTREPALAGASLAWHEIGA
SKDESIVRSAGKPFSPSGGLKLLQGNLGRSVIKVSAVPDDRHVIEAPARVFDSQEALHAAFNAKELDRDMVCVVRWQGPQ
ANGMPELHKLTPPLAVLQGKGFRVALVTDGRMSGASGKVPAAIHVSPEAAAGGPLAKVRDGDMIRLDAVTGELQVLVPEA
EWVARQVDTMPPALRRDNGIGLGRELFTGMRRHALTAEEGALSWM
>Mature_604_residues
ALHPAISHITARIAERSRPTRGAYLQQLQVAARRDPGVDRMGCANVAHAVAGIPLDDRFKVITHKAPNIGIVNAYNDMLS
AHVPLQGYPALIKDEARKLGATAQVAGGVPAMCDGVTQGTPGMELSLFSRDVIAMATAVALSHDMFDAALMLGVCDKIVP
GLLIGALHFGHLPTVFVPAGPMTTGLPNKEKARVREQAAQGLVGREGLLDAELKSYHSPGTCTFYGTANSNQLLLEAMGL
HVPGTAFVNPGNELREQLTREAARTVLGITKSKRFAPIGQIVDERAIVNAMVALLATGGSTNHLIHWVAVAHSAGIVIDW
NDFSDLSDVVPTLAHVYPNGSADVNQFQAAGGPGLIIRELLDAGLMHEDVLTVREGGIREYTREPALAGASLAWHEIGAS
KDESIVRSAGKPFSPSGGLKLLQGNLGRSVIKVSAVPDDRHVIEAPARVFDSQEALHAAFNAKELDRDMVCVVRWQGPQA
NGMPELHKLTPPLAVLQGKGFRVALVTDGRMSGASGKVPAAIHVSPEAAAGGPLAKVRDGDMIRLDAVTGELQVLVPEAE
WVARQVDTMPPALRRDNGIGLGRELFTGMRRHALTAEEGALSWM

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. [C]

COG id: COG0129

COG function: function code EG; Dihydroxyacid dehydratase/phosphogluconate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ilvD/edd family [H]

Homologues:

Organism=Escherichia coli, GI1788157, Length=602, Percent_Identity=56.8106312292359, Blast_Score=670, Evalue=0.0,
Organism=Escherichia coli, GI48994964, Length=541, Percent_Identity=30.3142329020333, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI2367371, Length=468, Percent_Identity=32.2649572649573, Blast_Score=165, Evalue=1e-41,
Organism=Escherichia coli, GI1786464, Length=481, Percent_Identity=31.1850311850312, Blast_Score=156, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6322476, Length=541, Percent_Identity=28.4658040665434, Blast_Score=179, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004786
- InterPro:   IPR015928
- InterPro:   IPR000581
- InterPro:   IPR020558 [H]

Pfam domain/function: PF00920 ILVD_EDD [H]

EC number: =4.2.1.12 [H]

Molecular weight: Translated: 64175; Mature: 64043

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00886 ILVD_EDD_1 ; PS00887 ILVD_EDD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALHPAISHITARIAERSRPTRGAYLQQLQVAARRDPGVDRMGCANVAHAVAGIPLDDRF
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCE
KVITHKAPNIGIVNAYNDMLSAHVPLQGYPALIKDEARKLGATAQVAGGVPAMCDGVTQG
EEEEECCCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHCCCCCHHHCCCCCC
TPGMELSLFSRDVIAMATAVALSHDMFDAALMLGVCDKIVPGLLIGALHFGHLPTVFVPA
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
GPMTTGLPNKEKARVREQAAQGLVGREGLLDAELKSYHSPGTCTFYGTANSNQLLLEAMG
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCEEEEEECC
LHVPGTAFVNPGNELREQLTREAARTVLGITKSKRFAPIGQIVDERAIVNAMVALLATGG
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
STNHLIHWVAVAHSAGIVIDWNDFSDLSDVVPTLAHVYPNGSADVNQFQAAGGPGLIIRE
CCCHHEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHH
LLDAGLMHEDVLTVREGGIREYTREPALAGASLAWHEIGASKDESIVRSAGKPFSPSGGL
HHHCCCHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCCCCCC
KLLQGNLGRSVIKVSAVPDDRHVIEAPARVFDSQEALHAAFNAKELDRDMVCVVRWQGPQ
EEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCHHHCCCCEEEEEEECCCC
ANGMPELHKLTPPLAVLQGKGFRVALVTDGRMSGASGKVPAAIHVSPEAAAGGPLAKVRD
CCCCCHHHHCCCCHHHCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCEECC
GDMIRLDAVTGELQVLVPEAEWVARQVDTMPPALRRDNGIGLGRELFTGMRRHALTAEEG
CCEEEEEEECCCEEEEECCHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHCCCCCCC
ALSWM
CCCCC
>Mature Secondary Structure 
ALHPAISHITARIAERSRPTRGAYLQQLQVAARRDPGVDRMGCANVAHAVAGIPLDDRF
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCE
KVITHKAPNIGIVNAYNDMLSAHVPLQGYPALIKDEARKLGATAQVAGGVPAMCDGVTQG
EEEEECCCCCEEEECHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHCCCCCHHHCCCCCC
TPGMELSLFSRDVIAMATAVALSHDMFDAALMLGVCDKIVPGLLIGALHFGHLPTVFVPA
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
GPMTTGLPNKEKARVREQAAQGLVGREGLLDAELKSYHSPGTCTFYGTANSNQLLLEAMG
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCEEEEEECC
LHVPGTAFVNPGNELREQLTREAARTVLGITKSKRFAPIGQIVDERAIVNAMVALLATGG
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
STNHLIHWVAVAHSAGIVIDWNDFSDLSDVVPTLAHVYPNGSADVNQFQAAGGPGLIIRE
CCCHHEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHH
LLDAGLMHEDVLTVREGGIREYTREPALAGASLAWHEIGASKDESIVRSAGKPFSPSGGL
HHHCCCHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCCCCCC
KLLQGNLGRSVIKVSAVPDDRHVIEAPARVFDSQEALHAAFNAKELDRDMVCVVRWQGPQ
EEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCHHHCCCCEEEEEEECCCC
ANGMPELHKLTPPLAVLQGKGFRVALVTDGRMSGASGKVPAAIHVSPEAAAGGPLAKVRD
CCCCCHHHHCCCCHHHCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCEECC
GDMIRLDAVTGELQVLVPEAEWVARQVDTMPPALRRDNGIGLGRELFTGMRRHALTAEEG
CCEEEEEEECCCEEEEECCHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHCCCCCCC
ALSWM
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8045900; 10984043 [H]