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The map label for this gene is idnD [H]

Identifier: 91789377

GI number: 91789377

Start: 3726010

End: 3727059

Strand: Reverse

Name: idnD [H]

Synonym: Bpro_3523

Alternate gene names: 91789377

Gene position: 3727059-3726010 (Counterclockwise)

Preceding gene: 91789378

Following gene: 91789376

Centisome position: 71.67

GC content: 66.57

Gene sequence:

>1050_bases
ATGCGCGCACTTGTTTGCCACGCTCCGCTGGATCTGCGCTTTGACACGTTCGTGTCCGACCAGCCAGGCCCGACCGAGCT
CGGCGTGCGCATTGCCTATGGCGGCATTTGCGGCTCGGACCTGCACTACTTCCAGCACGGCGGCTTTGGCACCGTGCGCA
TCCGGGAGCCCATGGTGCTGGGGCACGAGGTGTCGGGCGCGATCGAGTCGGTGGGCAGCGCCGTCACACAATTCCAGGTT
GGCCAGCGCATTGCGGTGTCGCCCTCGCGGCCCTGCGGCACCTGCCGCTACTGCAACCTGGGTTTGCAGAACCACTGCAT
GGAAATGCGCTTTTACGGCAGTGCCATGCGCTTCCCCCACGTGCAGGGCGCGTTTCGCGAGCACCTGGTGATTGATGCCA
GCCAGGCCCATCTGGTCGCCGACGAGCTGCCGCTGGCCGAGGCGGCGCTGGCCGAGCCGCTGTCGGTCGGCCTGCATGCC
ATCACACGCGCCGGCTCGGTGTTTGGCAAGCGCGTGCTGGTCACGGGCTGCGGTCCGATCGGCTTGCTGTTGATTGCCGG
CCTGCGGCGTGCCGGTGCTGCGCACATCATTGCAGCCGACATTGCCGACGTGCCCCTGGTCTGCGCCGCCACGCTGGGTG
CGGACGAGACCATCAACCTAGCCCGTCACCCCGGCGGCCTGGCGCCTTATGCGCTCAACAAGGGCATGATCGAGGTGATG
TTCGAAGCTTCCGGCAGCGACAAGGCCTTGCGCGGCGGGCTGGATGTGATGGCGCCGCGCGGCGTGGTCGTGATCGTGGG
CCTGGGCGGCGATATCAGCGTGCCGATGAACCTGCTGGTGGCCAAGGAACTGGATGTGCGCGGTACCTTCCGTTTTCATC
AGGAGTTTGCGGTCGCGGTGCGCTTTCTCAACCAGCGCCTCATCGACGGCCGGCCGGTGATCACGCACACCCTGAAGTTC
GACCAGGCGGCGGATGCCTTCAAGCTGGCGGGCGACAAGGGCCGGGCGCTGAAAGTGCTCATCGATTTCAATGCGCCGGC
GGCGGCATGA

Upstream 100 bases:

>100_bases
TACGTCGACGGCGGCGTGACCGCCACCCTCTGAGTCTTTAACTTTTTAATTTTTTGACTCTTTGACTTTTTGACCGACTT
TGCTATTTGAGGAGAAATTC

Downstream 100 bases:

>100_bases
CAATGTGCGCAGCCCCGACCTTGATAGCTACAACAAGACGACACCGGAGATTTCATTGACCACCTTCACCAAAGTCACCC
TGTACACCGGCACCGACGGC

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MRALVCHAPLDLRFDTFVSDQPGPTELGVRIAYGGICGSDLHYFQHGGFGTVRIREPMVLGHEVSGAIESVGSAVTQFQV
GQRIAVSPSRPCGTCRYCNLGLQNHCMEMRFYGSAMRFPHVQGAFREHLVIDASQAHLVADELPLAEAALAEPLSVGLHA
ITRAGSVFGKRVLVTGCGPIGLLLIAGLRRAGAAHIIAADIADVPLVCAATLGADETINLARHPGGLAPYALNKGMIEVM
FEASGSDKALRGGLDVMAPRGVVVIVGLGGDISVPMNLLVAKELDVRGTFRFHQEFAVAVRFLNQRLIDGRPVITHTLKF
DQAADAFKLAGDKGRALKVLIDFNAPAAA

Sequences:

>Translated_349_residues
MRALVCHAPLDLRFDTFVSDQPGPTELGVRIAYGGICGSDLHYFQHGGFGTVRIREPMVLGHEVSGAIESVGSAVTQFQV
GQRIAVSPSRPCGTCRYCNLGLQNHCMEMRFYGSAMRFPHVQGAFREHLVIDASQAHLVADELPLAEAALAEPLSVGLHA
ITRAGSVFGKRVLVTGCGPIGLLLIAGLRRAGAAHIIAADIADVPLVCAATLGADETINLARHPGGLAPYALNKGMIEVM
FEASGSDKALRGGLDVMAPRGVVVIVGLGGDISVPMNLLVAKELDVRGTFRFHQEFAVAVRFLNQRLIDGRPVITHTLKF
DQAADAFKLAGDKGRALKVLIDFNAPAAA
>Mature_349_residues
MRALVCHAPLDLRFDTFVSDQPGPTELGVRIAYGGICGSDLHYFQHGGFGTVRIREPMVLGHEVSGAIESVGSAVTQFQV
GQRIAVSPSRPCGTCRYCNLGLQNHCMEMRFYGSAMRFPHVQGAFREHLVIDASQAHLVADELPLAEAALAEPLSVGLHA
ITRAGSVFGKRVLVTGCGPIGLLLIAGLRRAGAAHIIAADIADVPLVCAATLGADETINLARHPGGLAPYALNKGMIEVM
FEASGSDKALRGGLDVMAPRGVVVIVGLGGDISVPMNLLVAKELDVRGTFRFHQEFAVAVRFLNQRLIDGRPVITHTLKF
DQAADAFKLAGDKGRALKVLIDFNAPAAA

Specific function: Catalyzes the NADH/NADPH-dependent oxidation of L- idonate to 5-ketogluconate (5KG) [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=347, Percent_Identity=32.2766570605187, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI4501929, Length=349, Percent_Identity=28.3667621776504, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4501933, Length=349, Percent_Identity=27.2206303724928, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI34577061, Length=349, Percent_Identity=27.2206303724928, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI156523966, Length=358, Percent_Identity=25.6983240223464, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4501939, Length=346, Percent_Identity=26.3005780346821, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI71743840, Length=357, Percent_Identity=25.2100840336134, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI262073058, Length=357, Percent_Identity=25.2100840336134, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI71565152, Length=356, Percent_Identity=23.314606741573, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI71565154, Length=358, Percent_Identity=25.6983240223464, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1790718, Length=316, Percent_Identity=40.8227848101266, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1788073, Length=321, Percent_Identity=29.595015576324, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1787863, Length=349, Percent_Identity=29.2263610315186, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1788407, Length=328, Percent_Identity=30.4878048780488, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790045, Length=338, Percent_Identity=28.4023668639053, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI226510992, Length=342, Percent_Identity=28.0701754385965, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788075, Length=350, Percent_Identity=27.4285714285714, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082125, Length=333, Percent_Identity=27.6276276276276, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786552, Length=354, Percent_Identity=26.271186440678, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786825, Length=386, Percent_Identity=24.3523316062176, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786518, Length=206, Percent_Identity=27.1844660194175, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081918, Length=222, Percent_Identity=29.7297297297297, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=336, Percent_Identity=34.8214285714286, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17562878, Length=338, Percent_Identity=33.7278106508876, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17562584, Length=342, Percent_Identity=26.6081871345029, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25146526, Length=377, Percent_Identity=27.5862068965517, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71997431, Length=377, Percent_Identity=26.790450928382, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565904, Length=356, Percent_Identity=27.247191011236, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=363, Percent_Identity=25.068870523416, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562582, Length=339, Percent_Identity=25.9587020648968, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=312, Percent_Identity=32.6923076923077, Blast_Score=166, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6319955, Length=313, Percent_Identity=33.2268370607029, Blast_Score=159, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6322619, Length=313, Percent_Identity=33.2268370607029, Blast_Score=159, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6319257, Length=381, Percent_Identity=27.2965879265092, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319258, Length=313, Percent_Identity=30.0319488817891, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6320033, Length=352, Percent_Identity=25, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319621, Length=263, Percent_Identity=29.277566539924, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323729, Length=277, Percent_Identity=25.6317689530686, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=130, Percent_Identity=31.5384615384615, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=178, Percent_Identity=27.5280898876405, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17737897, Length=343, Percent_Identity=32.0699708454811, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI17137530, Length=355, Percent_Identity=31.2676056338028, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI17737895, Length=356, Percent_Identity=26.4044943820225, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI45550770, Length=327, Percent_Identity=22.9357798165138, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45551930, Length=327, Percent_Identity=22.9357798165138, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221457811, Length=327, Percent_Identity=22.9357798165138, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.264 [H]

Molecular weight: Translated: 37002; Mature: 37002

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALVCHAPLDLRFDTFVSDQPGPTELGVRIAYGGICGSDLHYFQHGGFGTVRIREPMVL
CCEEEEECCCCCEEEEEECCCCCCHHEEEEEEECCCCCCCCHHHHCCCEEEEEEECCEEE
GHEVSGAIESVGSAVTQFQVGQRIAVSPSRPCGTCRYCNLGLQNHCMEMRFYGSAMRFPH
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEECCCHHHHHHHEEECCCHHCCCC
VQGAFREHLVIDASQAHLVADELPLAEAALAEPLSVGLHAITRAGSVFGKRVLVTGCGPI
HHHHHHHHEEEECCCCEEEHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCEEEEECCCHH
GLLLIAGLRRAGAAHIIAADIADVPLVCAATLGADETINLARHPGGLAPYALNKGMIEVM
HHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCEEEHCCCCCCCCCHHHCCCEEEEE
FEASGSDKALRGGLDVMAPRGVVVIVGLGGDISVPMNLLVAKELDVRGTFRFHQEFAVAV
EECCCCCCHHHCCCEEECCCCEEEEEECCCCCCCCEEEEEEEECCCCEEEHHHHHHHHHH
RFLNQRLIDGRPVITHTLKFDQAADAFKLAGDKGRALKVLIDFNAPAAA
HHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MRALVCHAPLDLRFDTFVSDQPGPTELGVRIAYGGICGSDLHYFQHGGFGTVRIREPMVL
CCEEEEECCCCCEEEEEECCCCCCHHEEEEEEECCCCCCCCHHHHCCCEEEEEEECCEEE
GHEVSGAIESVGSAVTQFQVGQRIAVSPSRPCGTCRYCNLGLQNHCMEMRFYGSAMRFPH
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEECCCHHHHHHHEEECCCHHCCCC
VQGAFREHLVIDASQAHLVADELPLAEAALAEPLSVGLHAITRAGSVFGKRVLVTGCGPI
HHHHHHHHEEEECCCCEEEHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCEEEEECCCHH
GLLLIAGLRRAGAAHIIAADIADVPLVCAATLGADETINLARHPGGLAPYALNKGMIEVM
HHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCEEEHCCCCCCCCCHHHCCCEEEEE
FEASGSDKALRGGLDVMAPRGVVVIVGLGGDISVPMNLLVAKELDVRGTFRFHQEFAVAV
EECCCCCCHHHCCCEEECCCCEEEEEECCCCCCCCEEEEEEEECCCCEEEHHHHHHHHHH
RFLNQRLIDGRPVITHTLKFDQAADAFKLAGDKGRALKVLIDFNAPAAA
HHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]