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The map label for this gene is tpiA [H]

Identifier: 91789118

GI number: 91789118

Start: 3447875

End: 3448612

Strand: Reverse

Name: tpiA [H]

Synonym: Bpro_3258

Alternate gene names: 91789118

Gene position: 3448612-3447875 (Counterclockwise)

Preceding gene: 91789119

Following gene: 91789117

Centisome position: 66.32

GC content: 64.5

Gene sequence:

>738_bases
ATGAATGGCAGTCTGGCTGCCAATGCCGCGTTGCTGGAGGCGCTGGGGGAAGGGCTGAAAGACCTGAGCCTCCCGCTCAC
CTGCGAGGTGGCCGTGTGCGTACCAGCGCCCTACCTGGCACAGGTTCAAGGCCTGAAATCGAGCCGATCCAGCCTGTCAG
CCCTGGCAGTGGGGGCGCAGGATGTTTCGGCGCAAGCCTCGGGTGCCTACACCGGCGAGGTCAGTGCGGCCATGCTCCAG
GACTTCGGCTGCCGGTATGTGATCGTGGGCCATTCCGAGCGTCGCCAGTACCACGGCGAATCAGATGCGCTGGTGGCCGA
CAAGGCCAAGGCGGCACTGGCGGCAGGGATCACGCCCATCGTCTGCATTGGTGAAACGCTGGCCGAGCGCGAGGGCGGCC
ACACGGAAGAGGTGGTCAAGCGCCAGCTTGCCGCGGTGATCCATGTCAACGGGCACTGCATCAGCGAGATCGTGGTGGCC
TACGAACCCGTCTGGGCCATAGGCACCGGAAAAACGGCTTCGCCCGAAGAGGCGCAGGCGGTTCATGCGGTGCTGCGGGC
CCAGCTCAGGGCGGCGACCGACCATCCGATGCGTGTGAAAATCCTGTACGGCGGCAGCATGAATGCGGCCAATGCGGCAG
CGCTCCTGAGCCAGCCCGACATCGACGGCGGCCTGATAGGCGGCGCCTCGCTCAAAGCCCCGGATTTTTTGAAAATTATT
GCTGCAGCCCAGATTTGA

Upstream 100 bases:

>100_bases
CCACGCACTGATGGAGTCCAACCAGCATGTCGGAAAAATCGTTTTAACCTGGTAATCAAGGCCAAGCAGGATGAAAAAGC
TGATTGCGGGAAACTGGAAG

Downstream 100 bases:

>100_bases
CGGCTGCAGAACGCTATTAATTTAGGAGTAGATATGAACGTTGTATTGACCATTGTCCTTGCCCTGCAAATGCTCGCCGC
CTTAGGCATGATTGGCCTGA

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNGSLAANAALLEALGEGLKDLSLPLTCEVAVCVPAPYLAQVQGLKSSRSSLSALAVGAQDVSAQASGAYTGEVSAAMLQ
DFGCRYVIVGHSERRQYHGESDALVADKAKAALAAGITPIVCIGETLAEREGGHTEEVVKRQLAAVIHVNGHCISEIVVA
YEPVWAIGTGKTASPEEAQAVHAVLRAQLRAATDHPMRVKILYGGSMNAANAAALLSQPDIDGGLIGGASLKAPDFLKII
AAAQI

Sequences:

>Translated_245_residues
MNGSLAANAALLEALGEGLKDLSLPLTCEVAVCVPAPYLAQVQGLKSSRSSLSALAVGAQDVSAQASGAYTGEVSAAMLQ
DFGCRYVIVGHSERRQYHGESDALVADKAKAALAAGITPIVCIGETLAEREGGHTEEVVKRQLAAVIHVNGHCISEIVVA
YEPVWAIGTGKTASPEEAQAVHAVLRAQLRAATDHPMRVKILYGGSMNAANAAALLSQPDIDGGLIGGASLKAPDFLKII
AAAQI
>Mature_245_residues
MNGSLAANAALLEALGEGLKDLSLPLTCEVAVCVPAPYLAQVQGLKSSRSSLSALAVGAQDVSAQASGAYTGEVSAAMLQ
DFGCRYVIVGHSERRQYHGESDALVADKAKAALAAGITPIVCIGETLAEREGGHTEEVVKRQLAAVIHVNGHCISEIVVA
YEPVWAIGTGKTASPEEAQAVHAVLRAQLRAATDHPMRVKILYGGSMNAANAAALLSQPDIDGGLIGGASLKAPDFLKII
AAAQI

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=238, Percent_Identity=45.7983193277311, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI226529917, Length=238, Percent_Identity=45.7983193277311, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI1790353, Length=227, Percent_Identity=50.2202643171806, Blast_Score=211, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17536593, Length=245, Percent_Identity=49.7959183673469, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6320255, Length=241, Percent_Identity=44.8132780082988, Blast_Score=197, Evalue=2e-51,
Organism=Drosophila melanogaster, GI28572008, Length=245, Percent_Identity=46.9387755102041, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI28572006, Length=245, Percent_Identity=46.9387755102041, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI28572004, Length=245, Percent_Identity=46.9387755102041, Blast_Score=199, Evalue=2e-51,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 25159; Mature: 25159

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGSLAANAALLEALGEGLKDLSLPLTCEVAVCVPAPYLAQVQGLKSSRSSLSALAVGAQ
CCCCHHHHHHHHHHHHCCHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCH
DVSAQASGAYTGEVSAAMLQDFGCRYVIVGHSERRQYHGESDALVADKAKAALAAGITPI
HCCCCCCCCCCCHHHHHHHHHCCCEEEEEECHHHHHHCCCCCCEEHHHHHHHHHHCCCCE
VCIGETLAEREGGHTEEVVKRQLAAVIHVNGHCISEIVVAYEPVWAIGTGKTASPEEAQA
EECCHHHHHCCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHCCEEEECCCCCCCCHHHHH
VHAVLRAQLRAATDHPMRVKILYGGSMNAANAAALLSQPDIDGGLIGGASLKAPDFLKII
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCEECCCCCCCCHHHHHH
AAAQI
HHHCC
>Mature Secondary Structure
MNGSLAANAALLEALGEGLKDLSLPLTCEVAVCVPAPYLAQVQGLKSSRSSLSALAVGAQ
CCCCHHHHHHHHHHHHCCHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCH
DVSAQASGAYTGEVSAAMLQDFGCRYVIVGHSERRQYHGESDALVADKAKAALAAGITPI
HCCCCCCCCCCCHHHHHHHHHCCCEEEEEECHHHHHHCCCCCCEEHHHHHHHHHHCCCCE
VCIGETLAEREGGHTEEVVKRQLAAVIHVNGHCISEIVVAYEPVWAIGTGKTASPEEAQA
EECCHHHHHCCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHCCEEEECCCCCCCCHHHHH
VHAVLRAQLRAATDHPMRVKILYGGSMNAANAAALLSQPDIDGGLIGGASLKAPDFLKII
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCEECCCCCCCCHHHHHH
AAAQI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA