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The map label for this gene is fadD [C]

Identifier: 91788972

GI number: 91788972

Start: 3284946

End: 3286805

Strand: Direct

Name: fadD [C]

Synonym: Bpro_3112

Alternate gene names: 91788972

Gene position: 3284946-3286805 (Clockwise)

Preceding gene: 91788971

Following gene: 91788973

Centisome position: 63.17

GC content: 64.46

Gene sequence:

>1860_bases
ATGACCAGCCCGAAATTTCGTCCCCTGACTTTTGGTGTCACCCGCGTCAATCTGCGCGACGGCGCGCCTGGCGTGCACTA
CCTGCGTGCCGATCAGCCCCTGCTGGACTACCCCGGCCGAATGACCGACCGCCTGCAGCACTGGGCGCAGGTGGCACCCG
ACCGGACCTTCATGGCGCGACGCGAAAAGCTTGCCGACTGCGGCACGGGCGACTGGCGTCATGTGAGCTACGCCAACGCC
TGGGCCAGCGCATGCAGCATCGCCCAGGCGCTGATCAACCGCGGCCTGAGCGTGGATCGGCCGGTGGCCATCCTGTCCGA
GAACGATCTCGAGCACGCGCTGCTGGGATTGGGCTGCATGTTGGCCGGGGTGCCCTTTGTGCCGGTCTCGCCGGCCTATT
CGCTGGTCAGCCAGGATTTCGACAAACTGCGCCACGTGTTCAGGACGGTGACGCCCGGCCTGGTCTTTGCAGCAGACGCG
ACGCGCTACGGCCGGGCCATCAAGGCGGCCGTTGACGCCGACATTGAAGTGGCGTTGACCAGCGGCGAGATGGACGGCCG
TGGCAGCACCTCGTTTGCGGAGTTGCTGGCCACGCCTGTCACGGCCCAGGTCGACGCCGCAATGGCCGCCACGGGGCCAG
ACACCATCGTGAAATTCCTGTTCACCAGCGGCTCGACCAAGCTGCCCAAGGCGGTGATCAACACCCAGCGCATGTGGTGC
GCCAACCAGCAGCAAATGACGCAGTCCATGCCCGTGCTGGCCAGCGAACCGCTGGTCCTGGTGGACTGGCTGCCCTGGAA
CCATACCTTTGGCGGCAACCATAACTTTGGCATGGTGGTCTTCCACGGCGGCACGATGTACATCGACGACGGCAAGCCCA
CCCCCGCGCTCATGGCAGAGACCCTGCGCAACCTGCGGGAGATTGCACCGACGGTGTATTTCAACGTGCCGACGGGGTTC
GAGGCCATTGCCAACGCCATGAAGACCGATGACACCCTGCGCAAAAACCTGTTGTCACGGGTGAAGATGTTCTTTTATGC
CGGTGCCTCGCTGGCCCAGCCAGTCTGGGACAGCCTGTACGCATCACAGGAAAGAGAAGTCGGGGAGCGCATCGTCATGA
CCACCGGACTGGGCATGACCGAGTCGGGGCCCTTTGCGATTTTTGTCACCAACCCGAACGTCAAGGCGGGCGACCTGGGC
GTGCCGACACCGGGGATGGAACTCAAGCTGGTCGACATGGATGGCAAGACCGAAGTGCGCTACCGCGGCCCCAACATCTC
GCCGGGCTACTGGCGCGACCCCAAGGAGTCGGCGGCGCATTTTGACGAGGAAGGCTTTTTTTGTTCGGGCGATGCGGTCA
AGTGGATTGACGAGACCGACGTTCACCAGGGATTGAAGTTTGACGGCCGCATTGCCGAAGACTTCAAGCTGGCCACCGGC
ACCTTCGTGAGCGTGGGCCCCCTGCGCGCCCGGATCGTGGCAGCCGGCGCACCCTACATACAGGACGTGGTGCTGACCGG
CATCAACCTGAAAGAGGTGGGCGCCATGGTGTTCCCGACCCAGGCTGTGCGTGCGTTGAGCGGCCTCGACGCCGGCGCAC
CGATGGCCGATGTGCTGTCCAGCGCGCCGGTGATTGCCCACTTCCAGCATGTGATCGACACCCTGGCCAAAACCGCGTCC
GGCAGTGCCGGCCGCATTGCGCGCATGTGCCTGCTCGCCGAGCCGCCCACCCTGGACCGGGGTGAAGTCACCGACAAGGG
CTCGATCAACCAGCGCGCCGTGCTGGCGCACCGCGCCGAAACGGTAGAGGCGTTGCATGCCGACAGGCTGCACACCATCC
TGAAACCACAAGCGCTTTAA

Upstream 100 bases:

>100_bases
AGAAAAGCTGAAGCCGCGCGGCCCAGCACGGAACGACATATCACCCCATCACGCAACAAGCACAACAAGAAAAACGCGAG
CACGCCCGGAAGAGACAAGC

Downstream 100 bases:

>100_bases
AGGAACCCCCTCATGGCCACCCCAGGCTTTTTCTCCCACTTTGACGACATCTGGATGCTGGACGGCGTGCGCACGCCCAT
GGTCGATTACTGTGGCGCAC

Product: feruloyl-CoA synthase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 619; Mature: 618

Protein sequence:

>619_residues
MTSPKFRPLTFGVTRVNLRDGAPGVHYLRADQPLLDYPGRMTDRLQHWAQVAPDRTFMARREKLADCGTGDWRHVSYANA
WASACSIAQALINRGLSVDRPVAILSENDLEHALLGLGCMLAGVPFVPVSPAYSLVSQDFDKLRHVFRTVTPGLVFAADA
TRYGRAIKAAVDADIEVALTSGEMDGRGSTSFAELLATPVTAQVDAAMAATGPDTIVKFLFTSGSTKLPKAVINTQRMWC
ANQQQMTQSMPVLASEPLVLVDWLPWNHTFGGNHNFGMVVFHGGTMYIDDGKPTPALMAETLRNLREIAPTVYFNVPTGF
EAIANAMKTDDTLRKNLLSRVKMFFYAGASLAQPVWDSLYASQEREVGERIVMTTGLGMTESGPFAIFVTNPNVKAGDLG
VPTPGMELKLVDMDGKTEVRYRGPNISPGYWRDPKESAAHFDEEGFFCSGDAVKWIDETDVHQGLKFDGRIAEDFKLATG
TFVSVGPLRARIVAAGAPYIQDVVLTGINLKEVGAMVFPTQAVRALSGLDAGAPMADVLSSAPVIAHFQHVIDTLAKTAS
GSAGRIARMCLLAEPPTLDRGEVTDKGSINQRAVLAHRAETVEALHADRLHTILKPQAL

Sequences:

>Translated_619_residues
MTSPKFRPLTFGVTRVNLRDGAPGVHYLRADQPLLDYPGRMTDRLQHWAQVAPDRTFMARREKLADCGTGDWRHVSYANA
WASACSIAQALINRGLSVDRPVAILSENDLEHALLGLGCMLAGVPFVPVSPAYSLVSQDFDKLRHVFRTVTPGLVFAADA
TRYGRAIKAAVDADIEVALTSGEMDGRGSTSFAELLATPVTAQVDAAMAATGPDTIVKFLFTSGSTKLPKAVINTQRMWC
ANQQQMTQSMPVLASEPLVLVDWLPWNHTFGGNHNFGMVVFHGGTMYIDDGKPTPALMAETLRNLREIAPTVYFNVPTGF
EAIANAMKTDDTLRKNLLSRVKMFFYAGASLAQPVWDSLYASQEREVGERIVMTTGLGMTESGPFAIFVTNPNVKAGDLG
VPTPGMELKLVDMDGKTEVRYRGPNISPGYWRDPKESAAHFDEEGFFCSGDAVKWIDETDVHQGLKFDGRIAEDFKLATG
TFVSVGPLRARIVAAGAPYIQDVVLTGINLKEVGAMVFPTQAVRALSGLDAGAPMADVLSSAPVIAHFQHVIDTLAKTAS
GSAGRIARMCLLAEPPTLDRGEVTDKGSINQRAVLAHRAETVEALHADRLHTILKPQAL
>Mature_618_residues
TSPKFRPLTFGVTRVNLRDGAPGVHYLRADQPLLDYPGRMTDRLQHWAQVAPDRTFMARREKLADCGTGDWRHVSYANAW
ASACSIAQALINRGLSVDRPVAILSENDLEHALLGLGCMLAGVPFVPVSPAYSLVSQDFDKLRHVFRTVTPGLVFAADAT
RYGRAIKAAVDADIEVALTSGEMDGRGSTSFAELLATPVTAQVDAAMAATGPDTIVKFLFTSGSTKLPKAVINTQRMWCA
NQQQMTQSMPVLASEPLVLVDWLPWNHTFGGNHNFGMVVFHGGTMYIDDGKPTPALMAETLRNLREIAPTVYFNVPTGFE
AIANAMKTDDTLRKNLLSRVKMFFYAGASLAQPVWDSLYASQEREVGERIVMTTGLGMTESGPFAIFVTNPNVKAGDLGV
PTPGMELKLVDMDGKTEVRYRGPNISPGYWRDPKESAAHFDEEGFFCSGDAVKWIDETDVHQGLKFDGRIAEDFKLATGT
FVSVGPLRARIVAAGAPYIQDVVLTGINLKEVGAMVFPTQAVRALSGLDAGAPMADVLSSAPVIAHFQHVIDTLAKTASG
SAGRIARMCLLAEPPTLDRGEVTDKGSINQRAVLAHRAETVEALHADRLHTILKPQAL

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI40807491, Length=529, Percent_Identity=23.062381852552, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI57165412, Length=477, Percent_Identity=23.0607966457023, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI57165410, Length=455, Percent_Identity=23.2967032967033, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1788107, Length=308, Percent_Identity=24.6753246753247, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17556552, Length=354, Percent_Identity=24.0112994350282, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17558820, Length=397, Percent_Identity=24.4332493702771, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564090, Length=343, Percent_Identity=24.198250728863, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653035, Length=449, Percent_Identity=26.2806236080178, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI161076582, Length=401, Percent_Identity=26.6832917705736, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24648260, Length=389, Percent_Identity=29.0488431876607, Blast_Score=97, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 67053; Mature: 66922

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPKFRPLTFGVTRVNLRDGAPGVHYLRADQPLLDYPGRMTDRLQHWAQVAPDRTFMAR
CCCCCCCEEEEEEEEEEECCCCCCCEEEECCCCHHCCCCHHHHHHHHHHHHCCCHHHHHH
REKLADCGTGDWRHVSYANAWASACSIAQALINRGLSVDRPVAILSENDLEHALLGLGCM
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHH
LAGVPFVPVSPAYSLVSQDFDKLRHVFRTVTPGLVFAADATRYGRAIKAAVDADIEVALT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEEEE
SGEMDGRGSTSFAELLATPVTAQVDAAMAATGPDTIVKFLFTSGSTKLPKAVINTQRMWC
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHCCHHHHH
ANQQQMTQSMPVLASEPLVLVDWLPWNHTFGGNHNFGMVVFHGGTMYIDDGKPTPALMAE
CCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCEEEEECCCCCHHHHHH
TLRNLREIAPTVYFNVPTGFEAIANAMKTDDTLRKNLLSRVKMFFYAGASLAQPVWDSLY
HHHHHHHHCCEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ASQEREVGERIVMTTGLGMTESGPFAIFVTNPNVKAGDLGVPTPGMELKLVDMDGKTEVR
HHHHHHHCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEE
YRGPNISPGYWRDPKESAAHFDEEGFFCSGDAVKWIDETDVHQGLKFDGRIAEDFKLATG
EECCCCCCCCCCCCHHHHHCCCCCCCEECCCCEECCCHHHHHCCCCCCCCCCCCEEEECC
TFVSVGPLRARIVAAGAPYIQDVVLTGINLKEVGAMVFPTQAVRALSGLDAGAPMADVLS
CEEEECCCEEEEEECCCCHHHHHHHCCCCHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHH
SAPVIAHFQHVIDTLAKTASGSAGRIARMCLLAEPPTLDRGEVTDKGSINQRAVLAHRAE
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
TVEALHADRLHTILKPQAL
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSPKFRPLTFGVTRVNLRDGAPGVHYLRADQPLLDYPGRMTDRLQHWAQVAPDRTFMAR
CCCCCCEEEEEEEEEEECCCCCCCEEEECCCCHHCCCCHHHHHHHHHHHHCCCHHHHHH
REKLADCGTGDWRHVSYANAWASACSIAQALINRGLSVDRPVAILSENDLEHALLGLGCM
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHH
LAGVPFVPVSPAYSLVSQDFDKLRHVFRTVTPGLVFAADATRYGRAIKAAVDADIEVALT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEEEE
SGEMDGRGSTSFAELLATPVTAQVDAAMAATGPDTIVKFLFTSGSTKLPKAVINTQRMWC
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHCCHHHHH
ANQQQMTQSMPVLASEPLVLVDWLPWNHTFGGNHNFGMVVFHGGTMYIDDGKPTPALMAE
CCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCEEEEECCCCCHHHHHH
TLRNLREIAPTVYFNVPTGFEAIANAMKTDDTLRKNLLSRVKMFFYAGASLAQPVWDSLY
HHHHHHHHCCEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ASQEREVGERIVMTTGLGMTESGPFAIFVTNPNVKAGDLGVPTPGMELKLVDMDGKTEVR
HHHHHHHCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEE
YRGPNISPGYWRDPKESAAHFDEEGFFCSGDAVKWIDETDVHQGLKFDGRIAEDFKLATG
EECCCCCCCCCCCCHHHHHCCCCCCCEECCCCEECCCHHHHHCCCCCCCCCCCCEEEECC
TFVSVGPLRARIVAAGAPYIQDVVLTGINLKEVGAMVFPTQAVRALSGLDAGAPMADVLS
CEEEECCCEEEEEECCCCHHHHHHHCCCCHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHH
SAPVIAHFQHVIDTLAKTASGSAGRIARMCLLAEPPTLDRGEVTDKGSINQRAVLAHRAE
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
TVEALHADRLHTILKPQAL
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]