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The map label for this gene is nrdR

Identifier: 91788736

GI number: 91788736

Start: 3036299

End: 3036748

Strand: Direct

Name: nrdR

Synonym: Bpro_2875

Alternate gene names: 91788736

Gene position: 3036299-3036748 (Clockwise)

Preceding gene: 91788735

Following gene: 91788744

Centisome position: 58.39

GC content: 56.89

Gene sequence:

>450_bases
ATGAAATGCCCTTTCTGCGGCAACCTCGAGACCCAGGTGGTCGAAACCCGGGTGTCGGAAGATGCAGATTTCATACGCCG
CCGCCGCCAGTGCGGCGCGTGTGAAAAGCGCTTCACGACCTATGAACGGCCTGACGTCAATTTTCCGGCGATTGTCAAAA
AAGATGGGCGCCGCATTGAATACAAGCGCGGCAAGATCCTCGGCTCGATGAACCTGGCGCTGCGCAAGCGACCGGTGAGC
ACAGAGCAGATCGACTCTGCCATCGAACGGATTGAAGAAAAACTCCTGAGCCTGGGCGTTCGGGAAGTGCCCTCCAACCG
CCTCGGCGAATTGGTGATGCGTGAGCTTAAAAAGCTCGACAAAGTCGCCTACGTGCGCTTTGCCAGCGTCTATCGGTCTT
TTGAAGACATCGACGAATTCAAGACACTGGTGGACGAGGTCCGGCGCTGA

Upstream 100 bases:

>100_bases
CGATGCCGCCAATATCGAAGCGGTTCGCGCCAAGGTCAATGCCCTGACCAGCCGCTTCCCTGTTTACCGCTGAAGCGCAT
TTCGACGTCTTGGCAAACCA

Downstream 100 bases:

>100_bases
TCTGGGCTGCCCGATCTAAACGCAGGTGGCGACTACGACTTTCTGCACCCGGGGCCGACCCGCGCTGTTGATGACGATCT
GCCTGGCCTCGCCATTCAAC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKCPFCGNLETQVVETRVSEDADFIRRRRQCGACEKRFTTYERPDVNFPAIVKKDGRRIEYKRGKILGSMNLALRKRPVS
TEQIDSAIERIEEKLLSLGVREVPSNRLGELVMRELKKLDKVAYVRFASVYRSFEDIDEFKTLVDEVRR

Sequences:

>Translated_149_residues
MKCPFCGNLETQVVETRVSEDADFIRRRRQCGACEKRFTTYERPDVNFPAIVKKDGRRIEYKRGKILGSMNLALRKRPVS
TEQIDSAIERIEEKLLSLGVREVPSNRLGELVMRELKKLDKVAYVRFASVYRSFEDIDEFKTLVDEVRR
>Mature_149_residues
MKCPFCGNLETQVVETRVSEDADFIRRRRQCGACEKRFTTYERPDVNFPAIVKKDGRRIEYKRGKILGSMNLALRKRPVS
TEQIDSAIERIEEKLLSLGVREVPSNRLGELVMRELKKLDKVAYVRFASVYRSFEDIDEFKTLVDEVRR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=140, Percent_Identity=50, Blast_Score=143, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_POLSJ (Q129K2)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_549688.1
- STRING:   Q129K2
- GeneID:   4014450
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_2875
- NMPDR:   fig|296591.1.peg.5466
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q129K2
- ProtClustDB:   PRK00464
- BioCyc:   PSP296591:BPRO_2875-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17448; Mature: 17448

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCGNLETQVVETRVSEDADFIRRRRQCGACEKRFTTYERPDVNFPAIVKKDGRRIE
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHCCCCCCEEH
YKRGKILGSMNLALRKRPVSTEQIDSAIERIEEKLLSLGVREVPSNRLGELVMRELKKLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KVAYVRFASVYRSFEDIDEFKTLVDEVRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKCPFCGNLETQVVETRVSEDADFIRRRRQCGACEKRFTTYERPDVNFPAIVKKDGRRIE
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHCCCCCCEEH
YKRGKILGSMNLALRKRPVSTEQIDSAIERIEEKLLSLGVREVPSNRLGELVMRELKKLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KVAYVRFASVYRSFEDIDEFKTLVDEVRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA