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The map label for this gene is slt [C]

Identifier: 91788734

GI number: 91788734

Start: 3033833

End: 3034723

Strand: Direct

Name: slt [C]

Synonym: Bpro_2873

Alternate gene names: 91788734

Gene position: 3033833-3034723 (Clockwise)

Preceding gene: 91788731

Following gene: 91788735

Centisome position: 58.34

GC content: 60.49

Gene sequence:

>891_bases
ATGACAGCGCTAGGAAACCATGGCTTGATGCCGCACCTTGAGGCGCACTTTAAAAGTGTACGCAGCAGTCTTTCAAATAT
TGCTGACGATATTGCCCAGGGCTTTTTCGAGATCATCCACAACAGCTTTGCCCTCCTGGGGCTGGCCGTCGTGTTTGCGG
TGATCACCCTTGTCGCCCGACCCGATTTGCGTCAGGCGGGTGAATCCGAGCTGATCACCTGGCTGCAGGAGCGCCGGGAG
GCGGCGATCGGCTTTACCGAGCCCGCCGCCATTGACCGGGCCACCGCGTCCAACCCGAAAGACCTGCCATCCCAACAGGC
AGCCGTGGCTTACTGGCTGAGCAAAAAGTACGGCGTGGCACCGGAGCCTCTGAGCGTTCTGGTGTCAGAGGCATTCGAGA
TTGGCCAGAAAGCCAAGCTCGACCCCACCCTGATTCTGGCCATCATGGCAATCGAGTCGGGTTTCAACCCCTTTGCTCAA
AGCCCGGTCGGCGCGCAGGGCTTGATGCAGGTGATGACCAAGGTGCATCACGACAAGTATGAAAACTTTGGCGGCAAACT
GGCGGCGTTTGACCCGGTGACCAACCTTCGTGTCGGTGTCAAGGTGCTGCAGGAGTGCATTGCCCGGGCCGGCTCCATCG
AGGGAGGTCTGAAATATTACGTGGGCGCGGCGAACATGGAAGATGATGGCGGTTACGCCGGAAAAGTCATGGCCGAGCAC
GCTCGCCTGCTGACCGTGGTGGGGAGCAAGCGCCTTCTGCCCTCGCCGTTCTTCGCCAATCCGGCTCCGGCCCGCCCTAT
CCCGGCGTCCTTGCCGGCAAAACCTGGCGCCGGGGACGCTGGCGACGGCAGCAAAATGCCTGAAAAGGTAGCCTTCCTCA
GTCAGTCCTGA

Upstream 100 bases:

>100_bases
AACAAGGGGTCAACACCCACAAGGCCAGGCCTTGGTTTGATGGCGACCCAATCAAAGTCTGCATGGCCCCCGCGGCTGCG
CAGGCGTAGAAAGGAGTGCT

Downstream 100 bases:

>100_bases
CCCCTCGTCCAGCCCCCTGCCTTGGCTGGGTGGCTTGGGCTTGTAGAGCGCATCCTCGACGCCGGGCTCCATCCCGGCGT
TCTTTTGCCCTCGCCCGCCG

Product: lytic transglycosylase catalytic subunit

Products: 1,6-Anhydrobond [C]

Alternate protein names: Transglycosylase; Transglycosylase SLT Family Protein; Transglycosylase SLT Family; Lytic Transglycosylase; Transglycosylase SLT Domain-Containing Lipoprotein; Transmembrane Protein; Transglycosylase Protein; Transglycosylase SLT Domain-Containing; Transmembrane Transglycosylase SLT Family Protein

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTALGNHGLMPHLEAHFKSVRSSLSNIADDIAQGFFEIIHNSFALLGLAVVFAVITLVARPDLRQAGESELITWLQERRE
AAIGFTEPAAIDRATASNPKDLPSQQAAVAYWLSKKYGVAPEPLSVLVSEAFEIGQKAKLDPTLILAIMAIESGFNPFAQ
SPVGAQGLMQVMTKVHHDKYENFGGKLAAFDPVTNLRVGVKVLQECIARAGSIEGGLKYYVGAANMEDDGGYAGKVMAEH
ARLLTVVGSKRLLPSPFFANPAPARPIPASLPAKPGAGDAGDGSKMPEKVAFLSQS

Sequences:

>Translated_296_residues
MTALGNHGLMPHLEAHFKSVRSSLSNIADDIAQGFFEIIHNSFALLGLAVVFAVITLVARPDLRQAGESELITWLQERRE
AAIGFTEPAAIDRATASNPKDLPSQQAAVAYWLSKKYGVAPEPLSVLVSEAFEIGQKAKLDPTLILAIMAIESGFNPFAQ
SPVGAQGLMQVMTKVHHDKYENFGGKLAAFDPVTNLRVGVKVLQECIARAGSIEGGLKYYVGAANMEDDGGYAGKVMAEH
ARLLTVVGSKRLLPSPFFANPAPARPIPASLPAKPGAGDAGDGSKMPEKVAFLSQS
>Mature_295_residues
TALGNHGLMPHLEAHFKSVRSSLSNIADDIAQGFFEIIHNSFALLGLAVVFAVITLVARPDLRQAGESELITWLQERREA
AIGFTEPAAIDRATASNPKDLPSQQAAVAYWLSKKYGVAPEPLSVLVSEAFEIGQKAKLDPTLILAIMAIESGFNPFAQS
PVGAQGLMQVMTKVHHDKYENFGGKLAAFDPVTNLRVGVKVLQECIARAGSIEGGLKYYVGAANMEDDGGYAGKVMAEHA
RLLTVVGSKRLLPSPFFANPAPARPIPASLPAKPGAGDAGDGSKMPEKVAFLSQS

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 31447; Mature: 31316

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALGNHGLMPHLEAHFKSVRSSLSNIADDIAQGFFEIIHNSFALLGLAVVFAVITLVAR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDLRQAGESELITWLQERREAAIGFTEPAAIDRATASNPKDLPSQQAAVAYWLSKKYGVA
CCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC
PEPLSVLVSEAFEIGQKAKLDPTLILAIMAIESGFNPFAQSPVGAQGLMQVMTKVHHDKY
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHH
ENFGGKLAAFDPVTNLRVGVKVLQECIARAGSIEGGLKYYVGAANMEDDGGYAGKVMAEH
HHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
ARLLTVVGSKRLLPSPFFANPAPARPIPASLPAKPGAGDAGDGSKMPEKVAFLSQS
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TALGNHGLMPHLEAHFKSVRSSLSNIADDIAQGFFEIIHNSFALLGLAVVFAVITLVAR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDLRQAGESELITWLQERREAAIGFTEPAAIDRATASNPKDLPSQQAAVAYWLSKKYGVA
CCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC
PEPLSVLVSEAFEIGQKAKLDPTLILAIMAIESGFNPFAQSPVGAQGLMQVMTKVHHDKY
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHH
ENFGGKLAAFDPVTNLRVGVKVLQECIARAGSIEGGLKYYVGAANMEDDGGYAGKVMAEH
HHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
ARLLTVVGSKRLLPSPFFANPAPARPIPASLPAKPGAGDAGDGSKMPEKVAFLSQS
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA