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The map label for this gene is lpxH [H]

Identifier: 91788730

GI number: 91788730

Start: 3024130

End: 3024957

Strand: Direct

Name: lpxH [H]

Synonym: Bpro_2869

Alternate gene names: 91788730

Gene position: 3024130-3024957 (Clockwise)

Preceding gene: 91788729

Following gene: 91788731

Centisome position: 58.15

GC content: 66.91

Gene sequence:

>828_bases
GTGCCCCAGATCGCGGAGCTCCATGCACCGCCTTCCTGGCGCACGGTCGATTTCATTGCAGACCTGCATTTGCAGGCCGG
GGAGCCCGCCACCTTCACGGCCTGGCGGCATTACCTTGAGAGCACGCCTGCCGATGCGGTGTTCATCCTGGGAGACCTGT
TTGAGGTCTGGGTCGGCGACGATGCGGTGAGCGCTGATTTACCGGCCCTGGCGACCGGCATGGAGACCCAGCCGGAGACC
AGCTTTGAAGACCGCTGCGCCCGCCTGCTGGGCGAGACAGCAGGCCGGCTGGCTGTTTTTTTCATGCACGGCAACCGCGA
CTTCCTGGTCGGCCAGACACCGGCCGGCCCGACGCTGATGGACCTGTGCAACATCACCTTGCTGGACGACCCGACCGTGC
TGGTGTTTCAAGGTCAGCGCTGGCTGCTGTCACATGGCGACGCGCTGTGCCTGGGTGATGTGGACTACCTGCAGTTTCGC
CAGCAGGTACGCAGCGCGGATTGGCAGAAGGCGTTTTTGGCCAGACCCCTGGCCGAACGCCAGGCCATTGCGCGCGGGCT
GCGCCAGCAAAGCCAGCAACAGCACGAACGCCGCAGGCAGTCGGGAGCCGGCTATGCCGACGTGGACACCGAGGCCGCCC
GCCAGTGGCTAGAGGCCGCGGGCGCGCGCACCCTGATTCACGGCCACACCCACCAGCCGGCAGTGCATGACCTCGGCCAG
GGCTTTGCCCGCGTGGTGCTCAGCGACTGGCATGCCGAGGGCAAGGTACCGCGCGCCGAAGTGCTGCGCCTGTCCGCCGA
CGGCTTGCGGCGCATTCCCCTGCTATAG

Upstream 100 bases:

>100_bases
TGCCCCTCGAAGACGTGGTGATCGAAAAAGCAGTGGCACTGGCCTGAAGCCCCTTCGGACTGAGCCTGCCCAAGTCCGGC
CCGTGACCTCCTCCTTGACC

Downstream 100 bases:

>100_bases
GCCTGGCTGCCGGCCTGCTCACAAAGCCTGCGATCAAGACGAAGACGCCTGCCTCATGCTGAACTGGCTGCGAACACTGC
TGGGGCGCGTCCGCGCCGAT

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MPQIAELHAPPSWRTVDFIADLHLQAGEPATFTAWRHYLESTPADAVFILGDLFEVWVGDDAVSADLPALATGMETQPET
SFEDRCARLLGETAGRLAVFFMHGNRDFLVGQTPAGPTLMDLCNITLLDDPTVLVFQGQRWLLSHGDALCLGDVDYLQFR
QQVRSADWQKAFLARPLAERQAIARGLRQQSQQQHERRRQSGAGYADVDTEAARQWLEAAGARTLIHGHTHQPAVHDLGQ
GFARVVLSDWHAEGKVPRAEVLRLSADGLRRIPLL

Sequences:

>Translated_275_residues
MPQIAELHAPPSWRTVDFIADLHLQAGEPATFTAWRHYLESTPADAVFILGDLFEVWVGDDAVSADLPALATGMETQPET
SFEDRCARLLGETAGRLAVFFMHGNRDFLVGQTPAGPTLMDLCNITLLDDPTVLVFQGQRWLLSHGDALCLGDVDYLQFR
QQVRSADWQKAFLARPLAERQAIARGLRQQSQQQHERRRQSGAGYADVDTEAARQWLEAAGARTLIHGHTHQPAVHDLGQ
GFARVVLSDWHAEGKVPRAEVLRLSADGLRRIPLL
>Mature_274_residues
PQIAELHAPPSWRTVDFIADLHLQAGEPATFTAWRHYLESTPADAVFILGDLFEVWVGDDAVSADLPALATGMETQPETS
FEDRCARLLGETAGRLAVFFMHGNRDFLVGQTPAGPTLMDLCNITLLDDPTVLVFQGQRWLLSHGDALCLGDVDYLQFRQ
QVRSADWQKAFLARPLAERQAIARGLRQQSQQQHERRRQSGAGYADVDTEAARQWLEAAGARTLIHGHTHQPAVHDLGQG
FARVVLSDWHAEGKVPRAEVLRLSADGLRRIPLL

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=260, Percent_Identity=36.9230769230769, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 30542; Mature: 30411

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQIAELHAPPSWRTVDFIADLHLQAGEPATFTAWRHYLESTPADAVFILGDLFEVWVGD
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
DAVSADLPALATGMETQPETSFEDRCARLLGETAGRLAVFFMHGNRDFLVGQTPAGPTLM
CCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCHHH
DLCNITLLDDPTVLVFQGQRWLLSHGDALCLGDVDYLQFRQQVRSADWQKAFLARPLAER
HHHCEEEECCCEEEEECCCEEEECCCCEEEECCHHHHHHHHHHHCCHHHHHHHHCHHHHH
QAIARGLRQQSQQQHERRRQSGAGYADVDTEAARQWLEAAGARTLIHGHTHQPAVHDLGQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
GFARVVLSDWHAEGKVPRAEVLRLSADGLRRIPLL
HHHHHHHHHHCCCCCCCHHHHEEECCCCCCCCCCC
>Mature Secondary Structure 
PQIAELHAPPSWRTVDFIADLHLQAGEPATFTAWRHYLESTPADAVFILGDLFEVWVGD
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
DAVSADLPALATGMETQPETSFEDRCARLLGETAGRLAVFFMHGNRDFLVGQTPAGPTLM
CCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCHHH
DLCNITLLDDPTVLVFQGQRWLLSHGDALCLGDVDYLQFRQQVRSADWQKAFLARPLAER
HHHCEEEECCCEEEEECCCEEEECCCCEEEECCHHHHHHHHHHHCCHHHHHHHHCHHHHH
QAIARGLRQQSQQQHERRRQSGAGYADVDTEAARQWLEAAGARTLIHGHTHQPAVHDLGQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
GFARVVLSDWHAEGKVPRAEVLRLSADGLRRIPLL
HHHHHHHHHHCCCCCCCHHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]