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The map label for this gene is rnr [H]

Identifier: 91788562

GI number: 91788562

Start: 2841974

End: 2844364

Strand: Reverse

Name: rnr [H]

Synonym: Bpro_2700

Alternate gene names: 91788562

Gene position: 2844364-2841974 (Counterclockwise)

Preceding gene: 91788563

Following gene: 91788561

Centisome position: 54.7

GC content: 62.86

Gene sequence:

>2391_bases
GTGACGCTTCACGAAAAGAGATTTCCTATCAAAACATCGCATCAAAATTCCGGCGCATCGTCCGGACTCCTCGCTGAATT
CGAGGGTACGGTTTCCGGCCACCGCGACGGCCACGGTTTCGTTCTGCGCGACGACGGCGAACCCGACATTTACCTGCCGC
CCAACGAAATGCGCGCGGTGCTGCACAAGGACCGCGTCAAGGCACGCATCGTGCGGCACGACCGGAAAAACCGGCCCGAA
GGACGCGTCACCGAAATCATCGAGCGCTCGCCCAACCCCATCATTGGCCGTCTGCTGCAGGAAAGCGGTGTCTGGCTGGT
AGCGCCCGAAGACAAGCGCTACGGCCAGGATATCCTGATCCCCAAAGGGGCGACGGGCACGGCCAAGAGCGGCCAGGTCG
TGGTGGTGCAACTGACCGAACCGCCGGCACTGTTTGGCCAACCGGTGGGGCGGGTGGTGGAAGTGCTGGGTGAAATTGAC
GATCCAGGCATGGAGATCGAGATCGCCGTGCGCAAATACGGCGTGCCGCACGAATTCAGCGACGAAGCATTGGCCCTGGC
GCGCACCCTGCCCGACGCGGTGCGACCGGCGGATAAAAAACACCGCGTGGACCTTACAGACATTTCCCTGGTAACCATTG
ACGGAGAAGATGCCCGCGATTTTGACGATGCCGTCTATTGCGAGCCTGCCAAAGTGGGTCGTGGCAAGGGCTGGCGTCTG
CTTGTGGCGATTGCAGACGTGAGCCATTACGTGGAAACCGGCAGCGCCATTGACATCGATGCCTATGACCGTGCCACCAG
CGTGTATTTTCCGCGCCGCGTGATTCCCATGCTGCCGGAAAAACTGTCGAACGGCTTGTGTTCGCTCAACCCCAATGTTG
AGCGCCTGTGCATGGTGTGCGACATGCTGATCAACGCCAAGGGCGAGGTTCACGCCTACCAGTTTTACCCGGCCGTGATG
TTCAGCCATGCCCGGCTTACCTACACCGAAGTAGCCGCCATTCTGGCCAACACGCGCGGCCCCGAGGCGGCGCAACGCAA
GGCACTGGTTCCGCACTTGCTGAATTTGCACGATGTGTACCAGGCTCTCCTGAAGGAGCGGGGCGTGCGCGGCGCCGTCG
ATTTTGAGACCACCGAGACCCAGATCGTGTGCGACGAAGCAGGGCGTATCGAGAAGATCGTGCCGCGCACCCGCAACGTG
GCGCACCGCCTGATTGAAGAGGCCATGCTGGCGGCGAATGTGTGCTCGGCCGATTTCATCGAGCAGAGCAAGCATGTGGG
TCTCTACCGCGTGCATGAAGGCCCGACCCCTGAAAAGAAGGAGATGTTGCGCAACTACCTCAAGGCGCTGGGCGTGGGCA
TGACGATTGGCGAGGAGCCGACGCCCGGTGAGTTCCAGCAGATTGCCGTTGCGACCAAAGACCGGCCCGATGCGCAGCAG
ATCCATTCCATGCTGCTGCGCTCCATGCAGCAGGCTATTTACACACCGATCAACAGCGGCCATTTTGGCCTGGCCTATGA
GGCCTATACCCACTTCACCAGCCCCATCCGTCGTTACCCCGACCTGCTGGTGCACCGCGTGATCAAGGCAGCGCTGACCA
AGTCCAAATACCAGCTGCCGGTATTGCCCACACCGGGCGAGGCCGAGGCCAAGCTGTCCAAGCGGCTGGCCTCCCGTGTC
AGGGATCCGTCGGAAAAGCCCAAAAAAATCAGTGCTGACCAGCTGGCCTGGCAGGCTGCCGGCCTGCACTGCAGCGCCAA
CGAGCGGCGTGCCGACGAGGCCAGCCGCGACGTTGAAGCCTGGCTCAAGTGCAAGTACATGCGCGAGCATCTGGGCGAGG
AGTTTGGCGGCGTGGTGACGGCGGCAACGGGTTTTGGCATCTTTGTCACGCTGGACGCCATGTATGTGGAAGGCCTGGTG
CACATCACCGAGCTCGGCGGCGAGTACTTTCGCTTTGACGAGGCCCGGCAGGAACTGCGCGGTGAGCGCACCGGCATCCG
CTACGCGATTGGCACGCGGGTGCGGGTGCAGGTCAGCCGGGTCGACCTGGACGGCCGCAAGATCGATTTCCGCCTGGTGC
ATGAGGGCGAAGCGTTGCTGGGCCGTGCCATGAAGGACAAGACCGGCGGCCATTCCGGGGAGTTGCCGGCGCAGGAGCGG
GGTACTTCTTCGCGCAAGGCCGGGGGGCAGCGTGCAGGCAAGGGCGCAGGAAAACGCTCCGAGGCGCGCTCCGGCGGCCG
CGGTACGGGTAGCGGGACCGCAAGGCGAGACGCCGTCACGGACCGAGGCGCCGACAGGACACCCGAATCGCCGATTCAGG
CGCTCAAGGCTGCGGTGAAAAAATCGGCCGGCAGTGCCAGTCGGAAGCAGGGAAAAAAGCCTCGCCGCTGA

Upstream 100 bases:

>100_bases
ATAAATATGGATTCAGACATGGCCAACCCAGCTTCAAGTCCACGGGTTTTCAGAGCCCGGTTTAACGGCCTGCCGCCTGT
TAGGCTGTAGGCTGTTGCCT

Downstream 100 bases:

>100_bases
CGTTTTCGGCTTTTTTAATCCTCTTGGCTTGCCTGAAAATTTATGCTGATCCGCATTCTGGACTTCCTGCTTGAGACATT
TTTCTTCCTGCTGATCGCCG

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 796; Mature: 795

Protein sequence:

>796_residues
MTLHEKRFPIKTSHQNSGASSGLLAEFEGTVSGHRDGHGFVLRDDGEPDIYLPPNEMRAVLHKDRVKARIVRHDRKNRPE
GRVTEIIERSPNPIIGRLLQESGVWLVAPEDKRYGQDILIPKGATGTAKSGQVVVVQLTEPPALFGQPVGRVVEVLGEID
DPGMEIEIAVRKYGVPHEFSDEALALARTLPDAVRPADKKHRVDLTDISLVTIDGEDARDFDDAVYCEPAKVGRGKGWRL
LVAIADVSHYVETGSAIDIDAYDRATSVYFPRRVIPMLPEKLSNGLCSLNPNVERLCMVCDMLINAKGEVHAYQFYPAVM
FSHARLTYTEVAAILANTRGPEAAQRKALVPHLLNLHDVYQALLKERGVRGAVDFETTETQIVCDEAGRIEKIVPRTRNV
AHRLIEEAMLAANVCSADFIEQSKHVGLYRVHEGPTPEKKEMLRNYLKALGVGMTIGEEPTPGEFQQIAVATKDRPDAQQ
IHSMLLRSMQQAIYTPINSGHFGLAYEAYTHFTSPIRRYPDLLVHRVIKAALTKSKYQLPVLPTPGEAEAKLSKRLASRV
RDPSEKPKKISADQLAWQAAGLHCSANERRADEASRDVEAWLKCKYMREHLGEEFGGVVTAATGFGIFVTLDAMYVEGLV
HITELGGEYFRFDEARQELRGERTGIRYAIGTRVRVQVSRVDLDGRKIDFRLVHEGEALLGRAMKDKTGGHSGELPAQER
GTSSRKAGGQRAGKGAGKRSEARSGGRGTGSGTARRDAVTDRGADRTPESPIQALKAAVKKSAGSASRKQGKKPRR

Sequences:

>Translated_796_residues
MTLHEKRFPIKTSHQNSGASSGLLAEFEGTVSGHRDGHGFVLRDDGEPDIYLPPNEMRAVLHKDRVKARIVRHDRKNRPE
GRVTEIIERSPNPIIGRLLQESGVWLVAPEDKRYGQDILIPKGATGTAKSGQVVVVQLTEPPALFGQPVGRVVEVLGEID
DPGMEIEIAVRKYGVPHEFSDEALALARTLPDAVRPADKKHRVDLTDISLVTIDGEDARDFDDAVYCEPAKVGRGKGWRL
LVAIADVSHYVETGSAIDIDAYDRATSVYFPRRVIPMLPEKLSNGLCSLNPNVERLCMVCDMLINAKGEVHAYQFYPAVM
FSHARLTYTEVAAILANTRGPEAAQRKALVPHLLNLHDVYQALLKERGVRGAVDFETTETQIVCDEAGRIEKIVPRTRNV
AHRLIEEAMLAANVCSADFIEQSKHVGLYRVHEGPTPEKKEMLRNYLKALGVGMTIGEEPTPGEFQQIAVATKDRPDAQQ
IHSMLLRSMQQAIYTPINSGHFGLAYEAYTHFTSPIRRYPDLLVHRVIKAALTKSKYQLPVLPTPGEAEAKLSKRLASRV
RDPSEKPKKISADQLAWQAAGLHCSANERRADEASRDVEAWLKCKYMREHLGEEFGGVVTAATGFGIFVTLDAMYVEGLV
HITELGGEYFRFDEARQELRGERTGIRYAIGTRVRVQVSRVDLDGRKIDFRLVHEGEALLGRAMKDKTGGHSGELPAQER
GTSSRKAGGQRAGKGAGKRSEARSGGRGTGSGTARRDAVTDRGADRTPESPIQALKAAVKKSAGSASRKQGKKPRR
>Mature_795_residues
TLHEKRFPIKTSHQNSGASSGLLAEFEGTVSGHRDGHGFVLRDDGEPDIYLPPNEMRAVLHKDRVKARIVRHDRKNRPEG
RVTEIIERSPNPIIGRLLQESGVWLVAPEDKRYGQDILIPKGATGTAKSGQVVVVQLTEPPALFGQPVGRVVEVLGEIDD
PGMEIEIAVRKYGVPHEFSDEALALARTLPDAVRPADKKHRVDLTDISLVTIDGEDARDFDDAVYCEPAKVGRGKGWRLL
VAIADVSHYVETGSAIDIDAYDRATSVYFPRRVIPMLPEKLSNGLCSLNPNVERLCMVCDMLINAKGEVHAYQFYPAVMF
SHARLTYTEVAAILANTRGPEAAQRKALVPHLLNLHDVYQALLKERGVRGAVDFETTETQIVCDEAGRIEKIVPRTRNVA
HRLIEEAMLAANVCSADFIEQSKHVGLYRVHEGPTPEKKEMLRNYLKALGVGMTIGEEPTPGEFQQIAVATKDRPDAQQI
HSMLLRSMQQAIYTPINSGHFGLAYEAYTHFTSPIRRYPDLLVHRVIKAALTKSKYQLPVLPTPGEAEAKLSKRLASRVR
DPSEKPKKISADQLAWQAAGLHCSANERRADEASRDVEAWLKCKYMREHLGEEFGGVVTAATGFGIFVTLDAMYVEGLVH
ITELGGEYFRFDEARQELRGERTGIRYAIGTRVRVQVSRVDLDGRKIDFRLVHEGEALLGRAMKDKTGGHSGELPAQERG
TSSRKAGGQRAGKGAGKRSEARSGGRGTGSGTARRDAVTDRGADRTPESPIQALKAAVKKSAGSASRKQGKKPRR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=478, Percent_Identity=31.1715481171548, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI190014623, Length=478, Percent_Identity=31.1715481171548, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI134288890, Length=410, Percent_Identity=30.7317073170732, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI19115966, Length=463, Percent_Identity=30.6695464362851, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI219521928, Length=463, Percent_Identity=30.6695464362851, Blast_Score=142, Evalue=2e-33,
Organism=Escherichia coli, GI87082383, Length=666, Percent_Identity=46.2462462462462, Blast_Score=591, Evalue=1e-170,
Organism=Escherichia coli, GI1787542, Length=518, Percent_Identity=29.3436293436293, Blast_Score=182, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI212645896, Length=430, Percent_Identity=30.9302325581395, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17553506, Length=420, Percent_Identity=31.9047619047619, Blast_Score=152, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6324552, Length=514, Percent_Identity=27.431906614786, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24649634, Length=472, Percent_Identity=29.6610169491525, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI19922976, Length=429, Percent_Identity=30.5361305361305, Blast_Score=145, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24654597, Length=429, Percent_Identity=30.5361305361305, Blast_Score=145, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24654592, Length=429, Percent_Identity=30.5361305361305, Blast_Score=145, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 87775; Mature: 87644

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLHEKRFPIKTSHQNSGASSGLLAEFEGTVSGHRDGHGFVLRDDGEPDIYLPPNEMRAV
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCEEECHHHHHHH
LHKDRVKARIVRHDRKNRPEGRVTEIIERSPNPIIGRLLQESGVWLVAPEDKRYGQDILI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCEEEE
PKGATGTAKSGQVVVVQLTEPPALFGQPVGRVVEVLGEIDDPGMEIEIAVRKYGVPHEFS
ECCCCCCCCCCCEEEEEECCCCHHHCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCC
DEALALARTLPDAVRPADKKHRVDLTDISLVTIDGEDARDFDDAVYCEPAKVGRGKGWRL
HHHHHHHHHCCHHHCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEECHHHCCCCCCCEE
LVAIADVSHYVETGSAIDIDAYDRATSVYFPRRVIPMLPEKLSNGLCSLNPNVERLCMVC
EEEEHHHHHHHHCCCEEEECCCCCCHHCCCCHHHHHHCHHHHCCCCEECCCCHHHHHHHH
DMLINAKGEVHAYQFYPAVMFSHARLTYTEVAAILANTRGPEAAQRKALVPHLLNLHDVY
HHHHCCCCCEEEEEEHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QALLKERGVRGAVDFETTETQIVCDEAGRIEKIVPRTRNVAHRLIEEAMLAANVCSADFI
HHHHHHCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQSKHVGLYRVHEGPTPEKKEMLRNYLKALGVGMTIGEEPTPGEFQQIAVATKDRPDAQQ
HHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEECCCCCCHHH
IHSMLLRSMQQAIYTPINSGHFGLAYEAYTHFTSPIRRYPDLLVHRVIKAALTKSKYQLP
HHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VLPTPGEAEAKLSKRLASRVRDPSEKPKKISADQLAWQAAGLHCSANERRADEASRDVEA
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHH
WLKCKYMREHLGEEFGGVVTAATGFGIFVTLDAMYVEGLVHITELGGEYFRFDEARQELR
HHHHHHHHHHHHHHHCCEEEECCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GERTGIRYAIGTRVRVQVSRVDLDGRKIDFRLVHEGEALLGRAMKDKTGGHSGELPAQER
CCCCCEEEEECCEEEEEEEEECCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCHHC
GTSSRKAGGQRAGKGAGKRSEARSGGRGTGSGTARRDAVTDRGADRTPESPIQALKAAVK
CCCHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
KSAGSASRKQGKKPRR
HCCCCCHHHCCCCCCC
>Mature Secondary Structure 
TLHEKRFPIKTSHQNSGASSGLLAEFEGTVSGHRDGHGFVLRDDGEPDIYLPPNEMRAV
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCEEECHHHHHHH
LHKDRVKARIVRHDRKNRPEGRVTEIIERSPNPIIGRLLQESGVWLVAPEDKRYGQDILI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCEEEE
PKGATGTAKSGQVVVVQLTEPPALFGQPVGRVVEVLGEIDDPGMEIEIAVRKYGVPHEFS
ECCCCCCCCCCCEEEEEECCCCHHHCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCC
DEALALARTLPDAVRPADKKHRVDLTDISLVTIDGEDARDFDDAVYCEPAKVGRGKGWRL
HHHHHHHHHCCHHHCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEECHHHCCCCCCCEE
LVAIADVSHYVETGSAIDIDAYDRATSVYFPRRVIPMLPEKLSNGLCSLNPNVERLCMVC
EEEEHHHHHHHHCCCEEEECCCCCCHHCCCCHHHHHHCHHHHCCCCEECCCCHHHHHHHH
DMLINAKGEVHAYQFYPAVMFSHARLTYTEVAAILANTRGPEAAQRKALVPHLLNLHDVY
HHHHCCCCCEEEEEEHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QALLKERGVRGAVDFETTETQIVCDEAGRIEKIVPRTRNVAHRLIEEAMLAANVCSADFI
HHHHHHCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQSKHVGLYRVHEGPTPEKKEMLRNYLKALGVGMTIGEEPTPGEFQQIAVATKDRPDAQQ
HHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEECCCCCCHHH
IHSMLLRSMQQAIYTPINSGHFGLAYEAYTHFTSPIRRYPDLLVHRVIKAALTKSKYQLP
HHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VLPTPGEAEAKLSKRLASRVRDPSEKPKKISADQLAWQAAGLHCSANERRADEASRDVEA
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHH
WLKCKYMREHLGEEFGGVVTAATGFGIFVTLDAMYVEGLVHITELGGEYFRFDEARQELR
HHHHHHHHHHHHHHHCCEEEECCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GERTGIRYAIGTRVRVQVSRVDLDGRKIDFRLVHEGEALLGRAMKDKTGGHSGELPAQER
CCCCCEEEEECCEEEEEEEEECCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCHHC
GTSSRKAGGQRAGKGAGKRSEARSGGRGTGSGTARRDAVTDRGADRTPESPIQALKAAVK
CCCHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
KSAGSASRKQGKKPRR
HCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]