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The map label for this gene is dctS [H]

Identifier: 91788535

GI number: 91788535

Start: 2811571

End: 2814192

Strand: Direct

Name: dctS [H]

Synonym: Bpro_2673

Alternate gene names: 91788535

Gene position: 2811571-2814192 (Clockwise)

Preceding gene: 91788529

Following gene: 91788536

Centisome position: 54.07

GC content: 62.28

Gene sequence:

>2622_bases
ATGACCATGCGGGTATCGCCGGGATACATCTCACTTAAACTGTTACCTTCCTCTATGTCCAAGCCCTCCTCCTTTTCCGA
CTCCGTTGCAGCGAGTCCCGCACCCCTCGCTTTCTGGCACCGCTGGTGGGGCAAACAGTCGCCATCGCGGCAGGACCGTT
TTATCACCTTGGGTCCGCTGCTGGCGGTGGTGCTGTTCCTGGCGGCTGTCATCGCGGCCTTCGCCTATCTGCGGATCGAG
GAAATAGACCGCGAGCAGCAGGCCGTCAAACGCGATGTCGAATACGCCCAGCAAAGGTTGCGCCTGCGGCTGCTTGAGAG
GCAGGAGCAGCTCATGCGCATTGGCCGGGATGTGTCCAACAAGGAGGTTGACGCCGAAGAGTTCATCGTCCAGGCCGAAT
CGCTGGTCAACCAGTACCCCGAACTGATGACTGTGACGTGGATCGACAGCAAGCGGCGCGTCAAGGTTGCCTATGCATCG
CCCAGCGTCCATCCCAGCCAGTCGCGCGTCGCAGGCGAGCAGCTCAAGGTCGGCGAGACAGACGGCACGTATGAACTGGC
GCGAGACCTGCGCCAGCCGGTTTACTCACGCCCCCTGGCAGCCAACGAACATAGCGGCCACAACGCACCTACCCTGCAAT
TGCAGGTGCCACTCGATGACCAGGGGAAATTTGACGGCGTCATCATGGGCGAATACTCCATCGATGGCTTGCTGCGCTTC
GGCGTTCCCACCGAAGTGACCGCCAAATACGCGGTGACCCTGATCAATGACAAGAACCTCGTGCTGGCTGGCAACTTGCC
ACCCAGGCGCAATCCGGCGGCCCGGCTGCTGCCGTGGTCTGACGCTGCTGCCGAGTACGAGATCCCGGTTTCACCTGTGG
GCAACGGGCTGCTGATTCGCGCAGAAGGCTACCGTGCCTCGCTGGGCGTTGTGGGCAGCGGCTTCTTCTGGCTGGTCAGC
GCCCTCAGCGCCCTGACCGTCTGGATGCTTCTGGGCACCTGGCGCCACACCCGCCGCCGCGTCCAGGCGCAGCAGGCGCT
GATATCCGAAACCAACTTCCGCCGAGCGATGGAAAATTCCATGCTCACCGGCATGCGCGCGCTGGATTTGCAGGGCCGCA
TTACCTACGTCAACCCCGCTTTCTGCGCAATGACGGGCTTTAGCGAAAGCGAGCTGGTGGGCCGTACCCCGCCCTTCCCG
CACTGGCCTGAAGCCGAGATCGATATCCTGATGGCGCGGCTTGACGACGAGTTGCACGGCCGCACCCCTCCCGGTGGATT
CGAAGTCCGTGTCAAACGCAAAAACGGCCAAATCTTTGATTCCCGCATGTATGTGTCGCCCCTGATTGACCCACGCGGGC
AACAGACGGGCTGGATGACGTCGATGACGGACATCACCGAGCCCAAGCGCATTCGCGAAGAACTGTCAGCCTCGTATGAA
CGCTTCACCACGGTGCTGGAGGGGCTGGATGCAGCGGTCTCCGTAGCGCCGCTGGGCAGCGAAGAACTGCTGTTTGCCAA
CAAGCTGTACCGGTCCTGGTTCGGCGGCGAGGTGTCCGGGCACATGAACCTGATTGCGCAGGCCGGTGTGCCGGCTGCCA
TGCCCACCGAAGACGCCATCGATCCGGTGGACGGCATGGCCGGATTTCCGACCGACACCCTGACCACCGCCCAGACGGAA
AACGCCGAAATATTTGTGCCCGACCTGGGCAAGTGGCTGGAAGTGCGCTCGCGCTACCTCACTTGGGTAGACGGCCGCCT
GGCGCAAATGGTGATCGCGACCGACATCACGCCACGGCGCCATGCCGAAGAACAGGCCGCGCAGCAAAACGAGCGCGCCC
AGACCGCGAGCCGGCTCATCACCATGGGCGAAATGGCATCCAGCGTGGCCCACGAGCTCAACCAGCCGCTGACCGCCATC
AACAACTATTGCAATGGCATGGTGTCGCGCATCAAGGGCCAGCAAATCAGCAATGAGGACCTGCTGATCGCGCTCGACAA
GACCGCCCGGCAGGCGCACCGTGCCGGCCAGATCATCCAGCGCATCCGCTCCTTTGTGAAACGCAGCGAGCCCAACCGAA
CCTCTGCCGATGTCGCCACCATGGTCAGCAACGCCATGGAGCTGGCCGACATCGAGTTGCGCCGCCACCATGTGCGGCTG
AGCCACTACATCGCGGCCCGTTTGCCCAACATCATGGTGGACCCCATCCTGATCGAACAGGTGCTCATCAACCTGATGAA
AAATGCGGCCGAGTCGATTGAGCAGGCGCACCTGCCCACGGCCCGCCGCAGCGTGGAATTGCGCGTCGTACCCAAGCACA
TCGAGGACCAGAGTGTGGTGGAGTTTTCGGTCCTTGACTCGGGCCGGGGCCTGTCGCCGGAAGTCAAGGCACGGCTCTAT
GAAGCCTTCTACTCCACCAAGGCTGAGGGCATGGGCATCGGCCTGAAACTGTGCCGCAGCATTGTCGAGTCCCACCAGGG
CAGGATGGAGGCCGAGAACCTCTACAATGGGGACGAAGTGGTGGGGTGCCGGTTCACTTTCTGGATCCCCGTGACGCCCC
TGCTTTCACCTGCACCTTCTGCTAGCGATACTGTAGCGGCCAAGGATGCCGGCGTTCACTAA

Upstream 100 bases:

>100_bases
TTTATATTATGAAATTTCAACTTCACCGCCTTTCTCACGAAAGTCAATGCGGGCAGAGAACACCCCTGCGACCAGACACT
GAAGCTCACCCCAAAAGATC

Downstream 100 bases:

>100_bases
AGCACCTTCAGGAATAGTTTCGAGAAGTTCACAAAAGAAAGTTTGGCATGAGCTTGATTCCCAAAAAAGGCACTGTTTAC
GTCATTGATGATGACGAGGG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 873; Mature: 872

Protein sequence:

>873_residues
MTMRVSPGYISLKLLPSSMSKPSSFSDSVAASPAPLAFWHRWWGKQSPSRQDRFITLGPLLAVVLFLAAVIAAFAYLRIE
EIDREQQAVKRDVEYAQQRLRLRLLERQEQLMRIGRDVSNKEVDAEEFIVQAESLVNQYPELMTVTWIDSKRRVKVAYAS
PSVHPSQSRVAGEQLKVGETDGTYELARDLRQPVYSRPLAANEHSGHNAPTLQLQVPLDDQGKFDGVIMGEYSIDGLLRF
GVPTEVTAKYAVTLINDKNLVLAGNLPPRRNPAARLLPWSDAAAEYEIPVSPVGNGLLIRAEGYRASLGVVGSGFFWLVS
ALSALTVWMLLGTWRHTRRRVQAQQALISETNFRRAMENSMLTGMRALDLQGRITYVNPAFCAMTGFSESELVGRTPPFP
HWPEAEIDILMARLDDELHGRTPPGGFEVRVKRKNGQIFDSRMYVSPLIDPRGQQTGWMTSMTDITEPKRIREELSASYE
RFTTVLEGLDAAVSVAPLGSEELLFANKLYRSWFGGEVSGHMNLIAQAGVPAAMPTEDAIDPVDGMAGFPTDTLTTAQTE
NAEIFVPDLGKWLEVRSRYLTWVDGRLAQMVIATDITPRRHAEEQAAQQNERAQTASRLITMGEMASSVAHELNQPLTAI
NNYCNGMVSRIKGQQISNEDLLIALDKTARQAHRAGQIIQRIRSFVKRSEPNRTSADVATMVSNAMELADIELRRHHVRL
SHYIAARLPNIMVDPILIEQVLINLMKNAAESIEQAHLPTARRSVELRVVPKHIEDQSVVEFSVLDSGRGLSPEVKARLY
EAFYSTKAEGMGIGLKLCRSIVESHQGRMEAENLYNGDEVVGCRFTFWIPVTPLLSPAPSASDTVAAKDAGVH

Sequences:

>Translated_873_residues
MTMRVSPGYISLKLLPSSMSKPSSFSDSVAASPAPLAFWHRWWGKQSPSRQDRFITLGPLLAVVLFLAAVIAAFAYLRIE
EIDREQQAVKRDVEYAQQRLRLRLLERQEQLMRIGRDVSNKEVDAEEFIVQAESLVNQYPELMTVTWIDSKRRVKVAYAS
PSVHPSQSRVAGEQLKVGETDGTYELARDLRQPVYSRPLAANEHSGHNAPTLQLQVPLDDQGKFDGVIMGEYSIDGLLRF
GVPTEVTAKYAVTLINDKNLVLAGNLPPRRNPAARLLPWSDAAAEYEIPVSPVGNGLLIRAEGYRASLGVVGSGFFWLVS
ALSALTVWMLLGTWRHTRRRVQAQQALISETNFRRAMENSMLTGMRALDLQGRITYVNPAFCAMTGFSESELVGRTPPFP
HWPEAEIDILMARLDDELHGRTPPGGFEVRVKRKNGQIFDSRMYVSPLIDPRGQQTGWMTSMTDITEPKRIREELSASYE
RFTTVLEGLDAAVSVAPLGSEELLFANKLYRSWFGGEVSGHMNLIAQAGVPAAMPTEDAIDPVDGMAGFPTDTLTTAQTE
NAEIFVPDLGKWLEVRSRYLTWVDGRLAQMVIATDITPRRHAEEQAAQQNERAQTASRLITMGEMASSVAHELNQPLTAI
NNYCNGMVSRIKGQQISNEDLLIALDKTARQAHRAGQIIQRIRSFVKRSEPNRTSADVATMVSNAMELADIELRRHHVRL
SHYIAARLPNIMVDPILIEQVLINLMKNAAESIEQAHLPTARRSVELRVVPKHIEDQSVVEFSVLDSGRGLSPEVKARLY
EAFYSTKAEGMGIGLKLCRSIVESHQGRMEAENLYNGDEVVGCRFTFWIPVTPLLSPAPSASDTVAAKDAGVH
>Mature_872_residues
TMRVSPGYISLKLLPSSMSKPSSFSDSVAASPAPLAFWHRWWGKQSPSRQDRFITLGPLLAVVLFLAAVIAAFAYLRIEE
IDREQQAVKRDVEYAQQRLRLRLLERQEQLMRIGRDVSNKEVDAEEFIVQAESLVNQYPELMTVTWIDSKRRVKVAYASP
SVHPSQSRVAGEQLKVGETDGTYELARDLRQPVYSRPLAANEHSGHNAPTLQLQVPLDDQGKFDGVIMGEYSIDGLLRFG
VPTEVTAKYAVTLINDKNLVLAGNLPPRRNPAARLLPWSDAAAEYEIPVSPVGNGLLIRAEGYRASLGVVGSGFFWLVSA
LSALTVWMLLGTWRHTRRRVQAQQALISETNFRRAMENSMLTGMRALDLQGRITYVNPAFCAMTGFSESELVGRTPPFPH
WPEAEIDILMARLDDELHGRTPPGGFEVRVKRKNGQIFDSRMYVSPLIDPRGQQTGWMTSMTDITEPKRIREELSASYER
FTTVLEGLDAAVSVAPLGSEELLFANKLYRSWFGGEVSGHMNLIAQAGVPAAMPTEDAIDPVDGMAGFPTDTLTTAQTEN
AEIFVPDLGKWLEVRSRYLTWVDGRLAQMVIATDITPRRHAEEQAAQQNERAQTASRLITMGEMASSVAHELNQPLTAIN
NYCNGMVSRIKGQQISNEDLLIALDKTARQAHRAGQIIQRIRSFVKRSEPNRTSADVATMVSNAMELADIELRRHHVRLS
HYIAARLPNIMVDPILIEQVLINLMKNAAESIEQAHLPTARRSVELRVVPKHIEDQSVVEFSVLDSGRGLSPEVKARLYE
AFYSTKAEGMGIGLKLCRSIVESHQGRMEAENLYNGDEVVGCRFTFWIPVTPLLSPAPSASDTVAAKDAGVH

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=26.3779527559055, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=26.5917602996255, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=259, Percent_Identity=25.0965250965251, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=283, Percent_Identity=23.6749116607774, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 97113; Mature: 96982

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMRVSPGYISLKLLPSSMSKPSSFSDSVAASPAPLAFWHRWWGKQSPSRQDRFITLGPL
CCEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEHHHH
LAVVLFLAAVIAAFAYLRIEEIDREQQAVKRDVEYAQQRLRLRLLERQEQLMRIGRDVSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KEVDAEEFIVQAESLVNQYPELMTVTWIDSKRRVKVAYASPSVHPSQSRVAGEQLKVGET
CCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHCCCCEECCCC
DGTYELARDLRQPVYSRPLAANEHSGHNAPTLQLQVPLDDQGKFDGVIMGEYSIDGLLRF
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCEEC
GVPTEVTAKYAVTLINDKNLVLAGNLPPRRNPAARLLPWSDAAAEYEIPVSPVGNGLLIR
CCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCEEECCCCCCCCEECCCCCCCCEEEEE
AEGYRASLGVVGSGFFWLVSALSALTVWMLLGTWRHTRRRVQAQQALISETNFRRAMENS
ECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLTGMRALDLQGRITYVNPAFCAMTGFSESELVGRTPPFPHWPEAEIDILMARLDDELHG
HHHCCCEEECCCEEEEECCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHCC
RTPPGGFEVRVKRKNGQIFDSRMYVSPLIDPRGQQTGWMTSMTDITEPKRIREELSASYE
CCCCCCEEEEEECCCCCEEECEEEECCCCCCCCCCCCCEECHHHCCCHHHHHHHHHHHHH
RFTTVLEGLDAAVSVAPLGSEELLFANKLYRSWFGGEVSGHMNLIAQAGVPAAMPTEDAI
HHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCC
DPVDGMAGFPTDTLTTAQTENAEIFVPDLGKWLEVRSRYLTWVDGRLAQMVIATDITPRR
CCCCCCCCCCCCCCEECCCCCCEEECCCHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHH
HAEEQAAQQNERAQTASRLITMGEMASSVAHELNQPLTAINNYCNGMVSRIKGQQISNED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
LLIALDKTARQAHRAGQIIQRIRSFVKRSEPNRTSADVATMVSNAMELADIELRRHHVRL
EEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SHYIAARLPNIMVDPILIEQVLINLMKNAAESIEQAHLPTARRSVELRVVPKHIEDQSVV
HHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEECCCCCCCCEE
EFSVLDSGRGLSPEVKARLYEAFYSTKAEGMGIGLKLCRSIVESHQGRMEAENLYNGDEV
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCE
VGCRFTFWIPVTPLLSPAPSASDTVAAKDAGVH
EEEEEEEEEECCCCCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
TMRVSPGYISLKLLPSSMSKPSSFSDSVAASPAPLAFWHRWWGKQSPSRQDRFITLGPL
CEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEHHHH
LAVVLFLAAVIAAFAYLRIEEIDREQQAVKRDVEYAQQRLRLRLLERQEQLMRIGRDVSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KEVDAEEFIVQAESLVNQYPELMTVTWIDSKRRVKVAYASPSVHPSQSRVAGEQLKVGET
CCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHCCCCEECCCC
DGTYELARDLRQPVYSRPLAANEHSGHNAPTLQLQVPLDDQGKFDGVIMGEYSIDGLLRF
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCEEC
GVPTEVTAKYAVTLINDKNLVLAGNLPPRRNPAARLLPWSDAAAEYEIPVSPVGNGLLIR
CCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCEEECCCCCCCCEECCCCCCCCEEEEE
AEGYRASLGVVGSGFFWLVSALSALTVWMLLGTWRHTRRRVQAQQALISETNFRRAMENS
ECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLTGMRALDLQGRITYVNPAFCAMTGFSESELVGRTPPFPHWPEAEIDILMARLDDELHG
HHHCCCEEECCCEEEEECCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHCC
RTPPGGFEVRVKRKNGQIFDSRMYVSPLIDPRGQQTGWMTSMTDITEPKRIREELSASYE
CCCCCCEEEEEECCCCCEEECEEEECCCCCCCCCCCCCEECHHHCCCHHHHHHHHHHHHH
RFTTVLEGLDAAVSVAPLGSEELLFANKLYRSWFGGEVSGHMNLIAQAGVPAAMPTEDAI
HHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCC
DPVDGMAGFPTDTLTTAQTENAEIFVPDLGKWLEVRSRYLTWVDGRLAQMVIATDITPRR
CCCCCCCCCCCCCCEECCCCCCEEECCCHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHH
HAEEQAAQQNERAQTASRLITMGEMASSVAHELNQPLTAINNYCNGMVSRIKGQQISNED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
LLIALDKTARQAHRAGQIIQRIRSFVKRSEPNRTSADVATMVSNAMELADIELRRHHVRL
EEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SHYIAARLPNIMVDPILIEQVLINLMKNAAESIEQAHLPTARRSVELRVVPKHIEDQSVV
HHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEECCCCCCCCEE
EFSVLDSGRGLSPEVKARLYEAFYSTKAEGMGIGLKLCRSIVESHQGRMEAENLYNGDEV
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCE
VGCRFTFWIPVTPLLSPAPSASDTVAAKDAGVH
EEEEEEEEEECCCCCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]