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The map label for this gene is prpC [H]

Identifier: 91788481

GI number: 91788481

Start: 2750080

End: 2750841

Strand: Direct

Name: prpC [H]

Synonym: Bpro_2619

Alternate gene names: 91788481

Gene position: 2750080-2750841 (Clockwise)

Preceding gene: 91788478

Following gene: 91788498

Centisome position: 52.88

GC content: 56.04

Gene sequence:

>762_bases
ATGTCCAAAGGTTATCGAATCACAGCGTCCACCGGAATCCATAAGGGCGACCGGGACTATCAACAAGACCAGGTCAACCT
GTATACCCACATTCGTATTCCGGGTTGCATGCTGGGCATAGTGGCTGACGGCATGGGCGGACGAAGCGGCGGGCGCAAAG
CCTCCGACCAGGTCATGCTCACCGCCAAACAGCTTTTTGAGCGCTATGCACCGGATATTGATGATGCGCCCTCCATGCTC
AAGCAGATCATTGAAGAGGCTCATCTTGTCATCAAGCTGACAGCGCTTTCTGCTGAACAGGAGCCGCACAGCACGCTGGC
AGCCTTTGTCATCAATCCTGGCGGAGACTGCCACTGGGCGCACACCGGTGACTCACGGATTTACCACTACCACGGCAACA
AGCTGATCCACAGAACGGTGGACCATTCCTACGTACAGACGCTGGTCGACAAGGGTGAGATTACCGAAGAGGAGGCCAAT
GTCCATCCGCAATCCAACATCTTGATGGGTTGCCTGGGAACAGAAGAATCACCCCCCATCACCCTGCACTTCATCCCGCA
ATTGCGTCCGGATGATGTGTTGCTTGCATGCAGCGATGGGGTATGGCACTACTTCAGCACCAGTGAAATCGGATCGGCTT
TGTCCATGCTGTCGCCGCGCGAAGCAACCGAGTTCCTGATCCAGAAAGCCAGATCGCGTGCACGGGGTGGCGGCGACAAC
CTGTCGCTGGTGATCGTCAAGCTCGAACCTTTGGGCCAGTAA

Upstream 100 bases:

>100_bases
AAATTTAAGTCCAAGGTTTTTTGTCCGTACGCGCTGCTTCATCTGATAATACGTCGATTGAGGCCATAAATCGAGTCTTG
CCGACTTGAACTATCAAACG

Downstream 100 bases:

>100_bases
GGCCAGGAGTCTGCGCCAGCCGAGGCAGCCTGGGTTCGCAAGACCTGGGCAGTGTGTATGCCCTTGCATGGGTTGCCAAA
TAGCAAAGCGGCCACTGGCG

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSKGYRITASTGIHKGDRDYQQDQVNLYTHIRIPGCMLGIVADGMGGRSGGRKASDQVMLTAKQLFERYAPDIDDAPSML
KQIIEEAHLVIKLTALSAEQEPHSTLAAFVINPGGDCHWAHTGDSRIYHYHGNKLIHRTVDHSYVQTLVDKGEITEEEAN
VHPQSNILMGCLGTEESPPITLHFIPQLRPDDVLLACSDGVWHYFSTSEIGSALSMLSPREATEFLIQKARSRARGGGDN
LSLVIVKLEPLGQ

Sequences:

>Translated_253_residues
MSKGYRITASTGIHKGDRDYQQDQVNLYTHIRIPGCMLGIVADGMGGRSGGRKASDQVMLTAKQLFERYAPDIDDAPSML
KQIIEEAHLVIKLTALSAEQEPHSTLAAFVINPGGDCHWAHTGDSRIYHYHGNKLIHRTVDHSYVQTLVDKGEITEEEAN
VHPQSNILMGCLGTEESPPITLHFIPQLRPDDVLLACSDGVWHYFSTSEIGSALSMLSPREATEFLIQKARSRARGGGDN
LSLVIVKLEPLGQ
>Mature_252_residues
SKGYRITASTGIHKGDRDYQQDQVNLYTHIRIPGCMLGIVADGMGGRSGGRKASDQVMLTAKQLFERYAPDIDDAPSMLK
QIIEEAHLVIKLTALSAEQEPHSTLAAFVINPGGDCHWAHTGDSRIYHYHGNKLIHRTVDHSYVQTLVDKGEITEEEANV
HPQSNILMGCLGTEESPPITLHFIPQLRPDDVLLACSDGVWHYFSTSEIGSALSMLSPREATEFLIQKARSRARGGGDNL
SLVIVKLEPLGQ

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 27840; Mature: 27709

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGYRITASTGIHKGDRDYQQDQVNLYTHIRIPGCMLGIVADGMGGRSGGRKASDQVML
CCCCEEEEEECCCCCCCCCCCCCCEEEEEEEECCHHEEEEEECCCCCCCCCCCCCCHHHH
TAKQLFERYAPDIDDAPSMLKQIIEEAHLVIKLTALSAEQEPHSTLAAFVINPGGDCHWA
HHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEEECCCCCEEEE
HTGDSRIYHYHGNKLIHRTVDHSYVQTLVDKGEITEEEANVHPQSNILMGCLGTEESPPI
ECCCCEEEEEECCEEEEHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCCCCCE
TLHFIPQLRPDDVLLACSDGVWHYFSTSEIGSALSMLSPREATEFLIQKARSRARGGGDN
EEEECCCCCCCCEEEEECCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
LSLVIVKLEPLGQ
EEEEEEEECCCCC
>Mature Secondary Structure 
SKGYRITASTGIHKGDRDYQQDQVNLYTHIRIPGCMLGIVADGMGGRSGGRKASDQVML
CCCEEEEEECCCCCCCCCCCCCCEEEEEEEECCHHEEEEEECCCCCCCCCCCCCCHHHH
TAKQLFERYAPDIDDAPSMLKQIIEEAHLVIKLTALSAEQEPHSTLAAFVINPGGDCHWA
HHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEEECCCCCEEEE
HTGDSRIYHYHGNKLIHRTVDHSYVQTLVDKGEITEEEANVHPQSNILMGCLGTEESPPI
ECCCCEEEEEECCEEEEHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCCCCCE
TLHFIPQLRPDDVLLACSDGVWHYFSTSEIGSALSMLSPREATEFLIQKARSRARGGGDN
EEEECCCCCCCCEEEEECCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
LSLVIVKLEPLGQ
EEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]