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The map label for this gene is degU [H]

Identifier: 91788405

GI number: 91788405

Start: 2665254

End: 2665946

Strand: Reverse

Name: degU [H]

Synonym: Bpro_2543

Alternate gene names: 91788405

Gene position: 2665946-2665254 (Counterclockwise)

Preceding gene: 91788421

Following gene: 91788404

Centisome position: 51.27

GC content: 61.62

Gene sequence:

>693_bases
GTGCCCTCGTTGTGGCCCGCCTTCCTGGCAGGCCAGCCCGGCAAGCCGGTACGTGTTGTGCTGATTGACGATGACGCGCA
CATGCGCAAGGTCATCTCTCATGAGCTGTTGGGTGATTTGCGCACCGATCTGGTGGCCCAGGCCGCCAGCATGCGCGAGG
GCCGCCGGCTGATTTCGCAGCACGAGTTCGACGTCATGCTGGTCGACCTGAATCTGGGCGACGGCAATGGCCTAGACCTG
ATTGATTACATGAAAACCGTTCACCCCCTGGCAGAAGCCGTGGTGATTTCGGCCATGGAAGACGAGCAGCACGCGCTGCG
CGCATTTGAGCTGGGAGCCACCGGCTACCTGGTCAAGAACTCCTGGTTTGGCAACTTTCCCCAGGCCGTGTTGCAGGTGG
TCAATGGCGGCGCGTCCATCACCCCCAACCTTGCGCGCCGGCTGCTGCACCGGCTGGAGCACACGCAGGAAGCGCCCCAC
CCCCACACCGCTGAAAAAAGGGACAAACTCTCCGACCGCGAAAAAGAAGTGCTCAAGGCGGTTGCGGCGGGTTACACCAG
CGGTGAGATCGGTTCGCGGCTGATGATCAGTTGCCAGACGGTCAACACCCACATCAAAAACATCTACCGCAAGCTGCAGG
TCCGCAGCCGGGCACAGGCCGTCAACTTTGCGGCCCATCGCGGCCTTTTGTAA

Upstream 100 bases:

>100_bases
GAGACATATGGACAACTCAAGCAGGGGCGGCTCCACGCTAATGCCCACGCCTGGTGGCACCTATGGTCATTCCCAGGCTG
CACGTTCATCGCAGGAGGCT

Downstream 100 bases:

>100_bases
AGCCCATCATGTTCAACGCGGCGCAACAGGGTCTGGCGCTGGCCGCCGCCGCGGTCGGCATACCACTGGCGTCTTTGGCA
CTCAGGGGCTCGCGTAAAAC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MPSLWPAFLAGQPGKPVRVVLIDDDAHMRKVISHELLGDLRTDLVAQAASMREGRRLISQHEFDVMLVDLNLGDGNGLDL
IDYMKTVHPLAEAVVISAMEDEQHALRAFELGATGYLVKNSWFGNFPQAVLQVVNGGASITPNLARRLLHRLEHTQEAPH
PHTAEKRDKLSDREKEVLKAVAAGYTSGEIGSRLMISCQTVNTHIKNIYRKLQVRSRAQAVNFAAHRGLL

Sequences:

>Translated_230_residues
MPSLWPAFLAGQPGKPVRVVLIDDDAHMRKVISHELLGDLRTDLVAQAASMREGRRLISQHEFDVMLVDLNLGDGNGLDL
IDYMKTVHPLAEAVVISAMEDEQHALRAFELGATGYLVKNSWFGNFPQAVLQVVNGGASITPNLARRLLHRLEHTQEAPH
PHTAEKRDKLSDREKEVLKAVAAGYTSGEIGSRLMISCQTVNTHIKNIYRKLQVRSRAQAVNFAAHRGLL
>Mature_229_residues
PSLWPAFLAGQPGKPVRVVLIDDDAHMRKVISHELLGDLRTDLVAQAASMREGRRLISQHEFDVMLVDLNLGDGNGLDLI
DYMKTVHPLAEAVVISAMEDEQHALRAFELGATGYLVKNSWFGNFPQAVLQVVNGGASITPNLARRLLHRLEHTQEAPHP
HTAEKRDKLSDREKEVLKAVAAGYTSGEIGSRLMISCQTVNTHIKNIYRKLQVRSRAQAVNFAAHRGLL

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=217, Percent_Identity=30.4147465437788, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786747, Length=210, Percent_Identity=22.8571428571429, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=29.3532338308458, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787473, Length=210, Percent_Identity=28.0952380952381, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25508; Mature: 25376

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLWPAFLAGQPGKPVRVVLIDDDAHMRKVISHELLGDLRTDLVAQAASMREGRRLISQ
CCCCCCHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HEFDVMLVDLNLGDGNGLDLIDYMKTVHPLAEAVVISAMEDEQHALRAFELGATGYLVKN
CCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
SWFGNFPQAVLQVVNGGASITPNLARRLLHRLEHTQEAPHPHTAEKRDKLSDREKEVLKA
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VAAGYTSGEIGSRLMISCQTVNTHIKNIYRKLQVRSRAQAVNFAAHRGLL
HHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PSLWPAFLAGQPGKPVRVVLIDDDAHMRKVISHELLGDLRTDLVAQAASMREGRRLISQ
CCCCCHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HEFDVMLVDLNLGDGNGLDLIDYMKTVHPLAEAVVISAMEDEQHALRAFELGATGYLVKN
CCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
SWFGNFPQAVLQVVNGGASITPNLARRLLHRLEHTQEAPHPHTAEKRDKLSDREKEVLKA
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VAAGYTSGEIGSRLMISCQTVNTHIKNIYRKLQVRSRAQAVNFAAHRGLL
HHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]