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The map label for this gene is wtpB [H]

Identifier: 91788361

GI number: 91788361

Start: 2615537

End: 2616328

Strand: Direct

Name: wtpB [H]

Synonym: Bpro_2498

Alternate gene names: 91788361

Gene position: 2615537-2616328 (Clockwise)

Preceding gene: 91788360

Following gene: 91788362

Centisome position: 50.3

GC content: 62.75

Gene sequence:

>792_bases
ATGCCGGGTGACATCTACGCGGCTGACGGCTTGCGGCACTCGCGCACACCGGCGCTGATAGGTGCGCTGACCTTAGCGCT
TATCGCCGGGCCGTTCATCGGTTTGGCATTTGCCACGCAGTGGGGAAAATTTCACTTCGCGCCGGGCGACATGGGATCTA
TTGGGGTATCGCTGGGTTACAGCCTGATCGCGCTGGTCCTGATCATTGCCCTCGGTACGCCGCTGGCATGGTGGCTGGCG
CGGCAATCGTTCCGCGGCAAGTGGGTGCTGGAGGCCATCATTCTGCTGGCCTTGCTCACCCCGCCGCTGGCAATGGGCAT
TTTGCTCACCACGCTGTTCGGTCCTTATGGTCCGATAGGCAATCTGGCTGCCCGCGCGGGCGTGGAGTTCACCAACTCGG
CCCTGGCCTTTGTGCTCGCGCAGTTCTACGGGGCCTTGCCTTACTACGTGCTGGCGGCCCGTGCCGCGTTTGAAGGTGTG
CCGCGCGAGCTGGAACACATCGCGCTGACCCTGGGCAAATCGCCGTGGCAGACATTCCTGCAGGTCAGCATGCCGCTGGC
GCGACTGGGTTTGGCGGCCGGCATTGCTTTGGCCTGGGTGCGGGCGCTGGGCGAGTTCGGCATCGTGCTGATCCTGGCTT
ATTACCCGCAGGGCATACCGGTCAAGCTCTGGGTCAATCTGCAGGATATCGGGCTGTCTTCCGTGTACCCGCTGCTGTGG
GCATTTTTTCTGGTGGCGATGCCTTTGCCCTTGATCCTTGGCTTGCTTTCGCGCCGCCAAGGCCTGTTCTGA

Upstream 100 bases:

>100_bases
ACGGCTACAGCCCACCCAAGGGCGGCCCGATTCAATAGCCAGCTGAACGCCGTGAACTCTCTATTCGACGCTGTGGGCCC
AACCTCGACATCGCATAAGC

Downstream 100 bases:

>100_bases
GTTCATGCGCATCGACTATCAGATCGATCATCCGATACGGCTGCAGGCCAGCCTGGAGGTCGAGGGCTTTACCGTCCTGC
TCGGGCAAAGCGGCGAAGGC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MPGDIYAADGLRHSRTPALIGALTLALIAGPFIGLAFATQWGKFHFAPGDMGSIGVSLGYSLIALVLIIALGTPLAWWLA
RQSFRGKWVLEAIILLALLTPPLAMGILLTTLFGPYGPIGNLAARAGVEFTNSALAFVLAQFYGALPYYVLAARAAFEGV
PRELEHIALTLGKSPWQTFLQVSMPLARLGLAAGIALAWVRALGEFGIVLILAYYPQGIPVKLWVNLQDIGLSSVYPLLW
AFFLVAMPLPLILGLLSRRQGLF

Sequences:

>Translated_263_residues
MPGDIYAADGLRHSRTPALIGALTLALIAGPFIGLAFATQWGKFHFAPGDMGSIGVSLGYSLIALVLIIALGTPLAWWLA
RQSFRGKWVLEAIILLALLTPPLAMGILLTTLFGPYGPIGNLAARAGVEFTNSALAFVLAQFYGALPYYVLAARAAFEGV
PRELEHIALTLGKSPWQTFLQVSMPLARLGLAAGIALAWVRALGEFGIVLILAYYPQGIPVKLWVNLQDIGLSSVYPLLW
AFFLVAMPLPLILGLLSRRQGLF
>Mature_262_residues
PGDIYAADGLRHSRTPALIGALTLALIAGPFIGLAFATQWGKFHFAPGDMGSIGVSLGYSLIALVLIIALGTPLAWWLAR
QSFRGKWVLEAIILLALLTPPLAMGILLTTLFGPYGPIGNLAARAGVEFTNSALAFVLAQFYGALPYYVLAARAAFEGVP
RELEHIALTLGKSPWQTFLQVSMPLARLGLAAGIALAWVRALGEFGIVLILAYYPQGIPVKLWVNLQDIGLSSVYPLLWA
FFLVAMPLPLILGLLSRRQGLF

Specific function: Part of the ABC transporter complex wtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=186, Percent_Identity=29.5698924731183, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786980, Length=184, Percent_Identity=35.3260869565217, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082099, Length=166, Percent_Identity=26.5060240963855, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28225; Mature: 28094

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGDIYAADGLRHSRTPALIGALTLALIAGPFIGLAFATQWGKFHFAPGDMGSIGVSLGY
CCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
SLIALVLIIALGTPLAWWLARQSFRGKWVLEAIILLALLTPPLAMGILLTTLFGPYGPIG
HHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
NLAARAGVEFTNSALAFVLAQFYGALPYYVLAARAAFEGVPRELEHIALTLGKSPWQTFL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
QVSMPLARLGLAAGIALAWVRALGEFGIVLILAYYPQGIPVKLWVNLQDIGLSSVYPLLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCHHHHHHHHH
AFFLVAMPLPLILGLLSRRQGLF
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PGDIYAADGLRHSRTPALIGALTLALIAGPFIGLAFATQWGKFHFAPGDMGSIGVSLGY
CCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
SLIALVLIIALGTPLAWWLARQSFRGKWVLEAIILLALLTPPLAMGILLTTLFGPYGPIG
HHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
NLAARAGVEFTNSALAFVLAQFYGALPYYVLAARAAFEGVPRELEHIALTLGKSPWQTFL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
QVSMPLARLGLAAGIALAWVRALGEFGIVLILAYYPQGIPVKLWVNLQDIGLSSVYPLLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCHHHHHHHHH
AFFLVAMPLPLILGLLSRRQGLF
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]