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The map label for this gene is caiD [C]

Identifier: 91788296

GI number: 91788296

Start: 2534277

End: 2535461

Strand: Direct

Name: caiD [C]

Synonym: Bpro_2431

Alternate gene names: 91788296

Gene position: 2534277-2535461 (Clockwise)

Preceding gene: 91788295

Following gene: 91788300

Centisome position: 48.73

GC content: 60.76

Gene sequence:

>1185_bases
ATGAATGAAAAAAGCACCAGCGCGAAAGACCGCGACGTGGCCGGGAAGACGGCAAGCCAGGAGGCGGGCGCAGGCATCAA
AAGCGACATTCTGGTGGAGCGGCGCGGAAGCGCCGGGCTGATCACGCTGAACCGGCCCAAGGCACTCAATGCCCTGTCGC
TGCAAATGGTCAGGGATCTTTCGAGCATCCTGCGGACCTGGCGGGACGACCCGTCTGTTCTGCTGGTGGCAATCCGCGGT
ACCAACAAGATTGGCCGGCCAGGCACTCCGGAGAGCCTGTTTGGCGGATTTTGTGCCGGCGGGGATATCCGGTTTTTCCA
CCAGGCCGCGCTGGCAGGGGATTCTGCGGCACTGGACGATTTTTTTACCGAGGAATACACCCTCAACCACCTGATTCACA
ACTATCCTAAACCTTACATCGCCTTCATGGACGGTACGGTGATGGGCGGCGGGATGGGGATCAGTCAGGGGGCCAAAGTT
CGCATCGTCACCGAACACACCAAAATGGCCATGCCCGAGACCCAGATCGGTCTGTTTCCCGACGTCGGAGGCGGCTACTT
CCTGAGCCGTTGCCCGGGACACGCCGGCGAATACCTGGCGCTGACCGGGGAGGTGATCGGTGCCGACGCAGCCATTGCCT
TCGGACTGGCAGACATCAAGCGTGATGCCGCACGGCTACCGGAGCTGTGGAACGAGCTGGGCAACCGGCCATTCACCTCA
GCCTCTGACGTGCAGGCATGGATTGCTACTGAATTGATAGCTGAAAGCCCCGGTAAAAATGGGGTTGACAGCAAAATCGA
CGCCTGTTTTTCACTGCTCAGGGTGAAGCACATCATCGATGCGCTGGAGGGGGCCGAGGATCCGTGGGCGGCGAAAACTG
CGGCCAAACTGCGCACACGCTCGCCGCTGATGCTGCATGTGACGCTGGAGCAGATTCGCCGGGCGCGCGGAATGAGCCTG
GCCGACGATTTGCGCATGGAGCGGGACATGGTGCATCACTGCTTTCACCTGCATCCCGGCGCACAAAGCGAGACGGTTGA
GGGCATACGCGCGCTGGCCATCGACAAGGACTACAAGCCCCGGTGGAATCCGGCACGCATTGAGGACGTGAAGCCGGGCA
TGGCAGATGCCTTTTTTGCCAGTCCCTGGACTGCAGAACTGCACCCGCTACGCGATCTTTGCTGA

Upstream 100 bases:

>100_bases
TCGGTGCCAATGAAGTGCCCGGGGCCAGCGTGCTGACGGGTGGGGCGCTGGTGATCGCTGCACTGGTCTTGAATGAACTG
ATTGGATGGAGGCAACGAGC

Downstream 100 bases:

>100_bases
GGTGTCCATTCGCCAAAGGTTTGGGCGGCGCGTGGGCCTGGACAAAACAGGAAGTTCATCCCGCCCTGAAAGCGCCGGGA
AATTAGAGTTGGCGTGGTGA

Product: 3-hydroxyisobutyryl-CoA hydrolase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MNEKSTSAKDRDVAGKTASQEAGAGIKSDILVERRGSAGLITLNRPKALNALSLQMVRDLSSILRTWRDDPSVLLVAIRG
TNKIGRPGTPESLFGGFCAGGDIRFFHQAALAGDSAALDDFFTEEYTLNHLIHNYPKPYIAFMDGTVMGGGMGISQGAKV
RIVTEHTKMAMPETQIGLFPDVGGGYFLSRCPGHAGEYLALTGEVIGADAAIAFGLADIKRDAARLPELWNELGNRPFTS
ASDVQAWIATELIAESPGKNGVDSKIDACFSLLRVKHIIDALEGAEDPWAAKTAAKLRTRSPLMLHVTLEQIRRARGMSL
ADDLRMERDMVHHCFHLHPGAQSETVEGIRALAIDKDYKPRWNPARIEDVKPGMADAFFASPWTAELHPLRDLC

Sequences:

>Translated_394_residues
MNEKSTSAKDRDVAGKTASQEAGAGIKSDILVERRGSAGLITLNRPKALNALSLQMVRDLSSILRTWRDDPSVLLVAIRG
TNKIGRPGTPESLFGGFCAGGDIRFFHQAALAGDSAALDDFFTEEYTLNHLIHNYPKPYIAFMDGTVMGGGMGISQGAKV
RIVTEHTKMAMPETQIGLFPDVGGGYFLSRCPGHAGEYLALTGEVIGADAAIAFGLADIKRDAARLPELWNELGNRPFTS
ASDVQAWIATELIAESPGKNGVDSKIDACFSLLRVKHIIDALEGAEDPWAAKTAAKLRTRSPLMLHVTLEQIRRARGMSL
ADDLRMERDMVHHCFHLHPGAQSETVEGIRALAIDKDYKPRWNPARIEDVKPGMADAFFASPWTAELHPLRDLC
>Mature_394_residues
MNEKSTSAKDRDVAGKTASQEAGAGIKSDILVERRGSAGLITLNRPKALNALSLQMVRDLSSILRTWRDDPSVLLVAIRG
TNKIGRPGTPESLFGGFCAGGDIRFFHQAALAGDSAALDDFFTEEYTLNHLIHNYPKPYIAFMDGTVMGGGMGISQGAKV
RIVTEHTKMAMPETQIGLFPDVGGGYFLSRCPGHAGEYLALTGEVIGADAAIAFGLADIKRDAARLPELWNELGNRPFTS
ASDVQAWIATELIAESPGKNGVDSKIDACFSLLRVKHIIDALEGAEDPWAAKTAAKLRTRSPLMLHVTLEQIRRARGMSL
ADDLRMERDMVHHCFHLHPGAQSETVEGIRALAIDKDYKPRWNPARIEDVKPGMADAFFASPWTAELHPLRDLC

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=370, Percent_Identity=35.6756756756757, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI37594469, Length=317, Percent_Identity=36.2776025236593, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI194097323, Length=193, Percent_Identity=32.1243523316062, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI221142681, Length=209, Percent_Identity=28.7081339712919, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787659, Length=190, Percent_Identity=28.4210526315789, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25144157, Length=371, Percent_Identity=41.2398921832884, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI25144160, Length=371, Percent_Identity=41.2398921832884, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI25145438, Length=194, Percent_Identity=31.9587628865979, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=199, Percent_Identity=29.1457286432161, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=314, Percent_Identity=33.7579617834395, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571729, Length=367, Percent_Identity=39.7820163487738, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI28571730, Length=367, Percent_Identity=39.7820163487738, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI20129971, Length=196, Percent_Identity=30.1020408163265, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24653477, Length=196, Percent_Identity=30.1020408163265, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24653139, Length=212, Percent_Identity=30.188679245283, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 42858; Mature: 42858

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKSTSAKDRDVAGKTASQEAGAGIKSDILVERRGSAGLITLNRPKALNALSLQMVRDL
CCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHH
SSILRTWRDDPSVLLVAIRGTNKIGRPGTPESLFGGFCAGGDIRFFHQAALAGDSAALDD
HHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCHHHHH
FFTEEYTLNHLIHNYPKPYIAFMDGTVMGGGMGISQGAKVRIVTEHTKMAMPETQIGLFP
HHHHHHHHHHHHHHCCCCEEEEECCEEECCCCCCCCCCEEEEEECCHHHCCCCCCCCCCC
DVGGGYFLSRCPGHAGEYLALTGEVIGADAAIAFGLADIKRDAARLPELWNELGNRPFTS
CCCCCHHHHCCCCCCCCEEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASDVQAWIATELIAESPGKNGVDSKIDACFSLLRVKHIIDALEGAEDPWAAKTAAKLRTR
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
SPLMLHVTLEQIRRARGMSLADDLRMERDMVHHCFHLHPGAQSETVEGIRALAIDKDYKP
CCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEECCCCCC
RWNPARIEDVKPGMADAFFASPWTAELHPLRDLC
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHCC
>Mature Secondary Structure
MNEKSTSAKDRDVAGKTASQEAGAGIKSDILVERRGSAGLITLNRPKALNALSLQMVRDL
CCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHH
SSILRTWRDDPSVLLVAIRGTNKIGRPGTPESLFGGFCAGGDIRFFHQAALAGDSAALDD
HHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCHHHHH
FFTEEYTLNHLIHNYPKPYIAFMDGTVMGGGMGISQGAKVRIVTEHTKMAMPETQIGLFP
HHHHHHHHHHHHHHCCCCEEEEECCEEECCCCCCCCCCEEEEEECCHHHCCCCCCCCCCC
DVGGGYFLSRCPGHAGEYLALTGEVIGADAAIAFGLADIKRDAARLPELWNELGNRPFTS
CCCCCHHHHCCCCCCCCEEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASDVQAWIATELIAESPGKNGVDSKIDACFSLLRVKHIIDALEGAEDPWAAKTAAKLRTR
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
SPLMLHVTLEQIRRARGMSLADDLRMERDMVHHCFHLHPGAQSETVEGIRALAIDKDYKP
CCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEECCCCCC
RWNPARIEDVKPGMADAFFASPWTAELHPLRDLC
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA