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The map label for this gene is cadA [H]

Identifier: 91788280

GI number: 91788280

Start: 2512662

End: 2514956

Strand: Direct

Name: cadA [H]

Synonym: Bpro_2415

Alternate gene names: 91788280

Gene position: 2512662-2514956 (Clockwise)

Preceding gene: 91788276

Following gene: 91788282

Centisome position: 48.32

GC content: 58.61

Gene sequence:

>2295_bases
ATGAAATTCCGCTTTCCGATTGTGATCATTGACGAAGACTTCCGCTCCGAGAATACCTCGGGGCTGAGTATTCGTGCGCT
GGCCCAGGCCATTGAAAGCGAAGGCTTCGAGGTGCTGGGCGTGACCAGCTACGGTGACCTGTCGCAGTTCGCCCAGCAGC
AAAGTCGTGCCAGTGCTTTTATCCTGTCAATTGATGACGAGGAGTTCACACCCGGCCCGGATCTGGATCCGGCCGTGCTG
AATCTGCGCAACTTCATCGAGGAGGTACGCCGCAAGAATCTTGACGTGCCGATTTACGTCTACGGTGAAACCAAAACCTC
GCGGCATATTCCCAACGACATCCTGCGCGAGTTGCACGGCTTCATTCACATGTTTGAAGACACGCCCGAGTTTGTGGCGC
GCCACATCCTTCGTGAGGCCAAGAGCTACCTCGAAGGGGTGCAGCCGCCTTTCTTCAAGGCGCTGCTGGACTACGCCGAA
GACGGCTCGTACTCATGGCACTGCCCGGGTCACTCGGGTGGTGTGGCATTTTTGAAGAGCCCGGTCGGGCAGATGTTTCA
CCAGTTCTTCGGCGAGAACATGCTGCGTGCCGACGTATGCAATGCAGTCGAGGAGTTGGGCCAACTGCTCGACCATGACG
GCGCGATTGGCGCCAGCGAGCGCAATGCCGCGCGTATCTTCAATGCGGACCACTGTTTCTTCGTCACTAACGGCACCTCC
ACCAGCAACAAGATGGTGTGGCACCACACCGTGGCGCCGGGCGATGTGGTGGTGGTGGACCGGAACTGCCACAAATCCAT
TCTGCACGCCATCATCATGACGGGTGCGATCCCGGTGTTTTTGAAGCCAACGCGCAACCACTTCGGCATCATCGGCCCGA
TTCCGCAAAGCGAATTCGAGCCCGAAGCCATCAAGGCCAAGATCCGGGCCAACCCGCTGCTCAAGGGTGTCGATGCAGAC
AAGGTCAAGCCGCGCGTGCTCACGCTCACGCAGTCGACCTATGACGGCGTGCTCTACAACACCGAAACCATCAAGGGCAT
GCTCGATGGCTACGTGGACAACCTGCACTTCGACGAGGCCTGGCTGCCGCACGCTGCATTTCACCCCTTCTATGGCAGCT
ACCACGCCATGGGCAAAAACCGCATTCGCCCGAAAAATGCCGTGGTGTACGCAACCCAGTCAATTCACAAGCTGCTGGCG
GGCATCAGCCAGGCCAGCCATGTGCTGGTGCAGGACTCGCAAAACACCAAGCTCGACAGGCACCTTTTCAACGAGGCCTA
CCTGATGCACACCTCGACTTCGCCGCAGTACAGCATCATCGCCAGCTGCGATGTGGCCGCCGCCATGATGGAGCCGCCCG
GCGGCACCGCGTTGGTCGAGGAGAGCATTGCCGAGGCACTGGACTTTCGCCGGGCCATGCGCAAGATCGACGATGAATAC
GGCAGTGACTGGTGGTTCAAGGTCTGGGGGCCGGACAAGCTGGTGGAAGAGGGCATTGGCCTGGCCGAGGACTGGATCAT
CAAGGGTGAGTCGCGCAGTGCCAAGAGGGCCAAAAACGGCGCCAATAACTGGCATGGCTTTGGCCAGATGGCAACAGGCT
TCAACATGCTCGACCCGATCAAGTCGACCATTGTCACGCCCGGGCTGGACCTCAATGGAAAATTCGCGAAAACCGGCATT
CCCGCCAGCATCGTGACCAAGTTTTTGGCCGAGCACGGGGTGATCGTGGAGAAAACCGGGCTTTACAGCTTCTTCATCAT
GTTCACCATCGGCATCACCAAAGGCCGCTGGAACACCCTGCTCACAGCGCTTCAGCAGTTCAAGGATGACTACGCCAAGA
ACCAGCCGATGTGGCGCATCCTGCCCGAGTTCTGCCAGAAGTACCCGAAATACGAGCGCATGGGCCTGGCTGACCTGTGT
CAGCACATTCATGCCCTTTACGCCAAATACGACATCGCGCGGTTAACGACCGAAGTCTATTTGAGTGACCTCGCACCGGT
CATGAAGCCCAGTGACGCCTATGCCCACATTGCCCACCGCACGACAGAGCGGGTCGAGATCGACCAGCTGGAAGGCCGCA
TCACCGTCGGGCTGGTCACGCCTTACCCACCCGGCATCCCGCTGCTGATTCCTGGCGAGGTGTTCAACAAGAAAATAGTT
GATTACCTCAAGTTTGCCCGTGAGTTCAACGCGCAATGCCCGGGGTTCGAGACCGATATCCACGGCTTGGTCGAAGAGGT
GGATGCCAAAGGCAAGGTCCGCTACTACGCCGACTGCGTGAAGAAAGCCCGCTGA

Upstream 100 bases:

>100_bases
GCCAGTCAAACCGTTCGGGCTCAACCTGTCTATGCCCATCCGAGCGTTTCCGTCATGCCCTCCGACAGGTTCAGGGCGCC
CATGAACTGCTTCCATCCCC

Downstream 100 bases:

>100_bases
AGCGGCAATTGTGCATGCGCCGCCCGTTTCAGACGGGCTGGTCTTCTCTCACCCGCATGAAGCTGGCAAACCTGGGGACG
CCGCTGCCGTTCAGGCCGCG

Product: ornithine decarboxylase

Products: NA

Alternate protein names: LDC [H]

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MKFRFPIVIIDEDFRSENTSGLSIRALAQAIESEGFEVLGVTSYGDLSQFAQQQSRASAFILSIDDEEFTPGPDLDPAVL
NLRNFIEEVRRKNLDVPIYVYGETKTSRHIPNDILRELHGFIHMFEDTPEFVARHILREAKSYLEGVQPPFFKALLDYAE
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVEELGQLLDHDGAIGASERNAARIFNADHCFFVTNGTS
TSNKMVWHHTVAPGDVVVVDRNCHKSILHAIIMTGAIPVFLKPTRNHFGIIGPIPQSEFEPEAIKAKIRANPLLKGVDAD
KVKPRVLTLTQSTYDGVLYNTETIKGMLDGYVDNLHFDEAWLPHAAFHPFYGSYHAMGKNRIRPKNAVVYATQSIHKLLA
GISQASHVLVQDSQNTKLDRHLFNEAYLMHTSTSPQYSIIASCDVAAAMMEPPGGTALVEESIAEALDFRRAMRKIDDEY
GSDWWFKVWGPDKLVEEGIGLAEDWIIKGESRSAKRAKNGANNWHGFGQMATGFNMLDPIKSTIVTPGLDLNGKFAKTGI
PASIVTKFLAEHGVIVEKTGLYSFFIMFTIGITKGRWNTLLTALQQFKDDYAKNQPMWRILPEFCQKYPKYERMGLADLC
QHIHALYAKYDIARLTTEVYLSDLAPVMKPSDAYAHIAHRTTERVEIDQLEGRITVGLVTPYPPGIPLLIPGEVFNKKIV
DYLKFAREFNAQCPGFETDIHGLVEEVDAKGKVRYYADCVKKAR

Sequences:

>Translated_764_residues
MKFRFPIVIIDEDFRSENTSGLSIRALAQAIESEGFEVLGVTSYGDLSQFAQQQSRASAFILSIDDEEFTPGPDLDPAVL
NLRNFIEEVRRKNLDVPIYVYGETKTSRHIPNDILRELHGFIHMFEDTPEFVARHILREAKSYLEGVQPPFFKALLDYAE
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVEELGQLLDHDGAIGASERNAARIFNADHCFFVTNGTS
TSNKMVWHHTVAPGDVVVVDRNCHKSILHAIIMTGAIPVFLKPTRNHFGIIGPIPQSEFEPEAIKAKIRANPLLKGVDAD
KVKPRVLTLTQSTYDGVLYNTETIKGMLDGYVDNLHFDEAWLPHAAFHPFYGSYHAMGKNRIRPKNAVVYATQSIHKLLA
GISQASHVLVQDSQNTKLDRHLFNEAYLMHTSTSPQYSIIASCDVAAAMMEPPGGTALVEESIAEALDFRRAMRKIDDEY
GSDWWFKVWGPDKLVEEGIGLAEDWIIKGESRSAKRAKNGANNWHGFGQMATGFNMLDPIKSTIVTPGLDLNGKFAKTGI
PASIVTKFLAEHGVIVEKTGLYSFFIMFTIGITKGRWNTLLTALQQFKDDYAKNQPMWRILPEFCQKYPKYERMGLADLC
QHIHALYAKYDIARLTTEVYLSDLAPVMKPSDAYAHIAHRTTERVEIDQLEGRITVGLVTPYPPGIPLLIPGEVFNKKIV
DYLKFAREFNAQCPGFETDIHGLVEEVDAKGKVRYYADCVKKAR
>Mature_764_residues
MKFRFPIVIIDEDFRSENTSGLSIRALAQAIESEGFEVLGVTSYGDLSQFAQQQSRASAFILSIDDEEFTPGPDLDPAVL
NLRNFIEEVRRKNLDVPIYVYGETKTSRHIPNDILRELHGFIHMFEDTPEFVARHILREAKSYLEGVQPPFFKALLDYAE
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVEELGQLLDHDGAIGASERNAARIFNADHCFFVTNGTS
TSNKMVWHHTVAPGDVVVVDRNCHKSILHAIIMTGAIPVFLKPTRNHFGIIGPIPQSEFEPEAIKAKIRANPLLKGVDAD
KVKPRVLTLTQSTYDGVLYNTETIKGMLDGYVDNLHFDEAWLPHAAFHPFYGSYHAMGKNRIRPKNAVVYATQSIHKLLA
GISQASHVLVQDSQNTKLDRHLFNEAYLMHTSTSPQYSIIASCDVAAAMMEPPGGTALVEESIAEALDFRRAMRKIDDEY
GSDWWFKVWGPDKLVEEGIGLAEDWIIKGESRSAKRAKNGANNWHGFGQMATGFNMLDPIKSTIVTPGLDLNGKFAKTGI
PASIVTKFLAEHGVIVEKTGLYSFFIMFTIGITKGRWNTLLTALQQFKDDYAKNQPMWRILPEFCQKYPKYERMGLADLC
QHIHALYAKYDIARLTTEVYLSDLAPVMKPSDAYAHIAHRTTERVEIDQLEGRITVGLVTPYPPGIPLLIPGEVFNKKIV
DYLKFAREFNAQCPGFETDIHGLVEEVDAKGKVRYYADCVKKAR

Specific function: Appears To Play A Role In pH Homeostasis By Consuming Protons And Neutralizing The Acidic By-Products Of Carbohydrate Fermentation. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=743, Percent_Identity=37.8196500672948, Blast_Score=517, Evalue=1e-147,
Organism=Escherichia coli, GI221142684, Length=768, Percent_Identity=36.0677083333333, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI1786384, Length=736, Percent_Identity=36.820652173913, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1786909, Length=704, Percent_Identity=30.8238636363636, Blast_Score=348, Evalue=7e-97,
Organism=Escherichia coli, GI87082193, Length=717, Percent_Identity=31.7991631799163, Blast_Score=346, Evalue=4e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.18 [H]

Molecular weight: Translated: 85684; Mature: 85684

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRFPIVIIDEDFRSENTSGLSIRALAQAIESEGFEVLGVTSYGDLSQFAQQQSRASAF
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEE
ILSIDDEEFTPGPDLDPAVLNLRNFIEEVRRKNLDVPIYVYGETKTSRHIPNDILRELHG
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHH
FIHMFEDTPEFVARHILREAKSYLEGVQPPFFKALLDYAEDGSYSWHCPGHSGGVAFLKS
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
PVGQMFHQFFGENMLRADVCNAVEELGQLLDHDGAIGASERNAARIFNADHCFFVTNGTS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEEECCCC
TSNKMVWHHTVAPGDVVVVDRNCHKSILHAIIMTGAIPVFLKPTRNHFGIIGPIPQSEFE
CCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCC
PEAIKAKIRANPLLKGVDADKVKPRVLTLTQSTYDGVLYNTETIKGMLDGYVDNLHFDEA
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHCCCCCCC
WLPHAAFHPFYGSYHAMGKNRIRPKNAVVYATQSIHKLLAGISQASHVLVQDSQNTKLDR
CCCCHHCCCCCCCHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCEEEEECCCCCHHHH
HLFNEAYLMHTSTSPQYSIIASCDVAAAMMEPPGGTALVEESIAEALDFRRAMRKIDDEY
HHHCCEEEEECCCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GSDWWFKVWGPDKLVEEGIGLAEDWIIKGESRSAKRAKNGANNWHGFGQMATGFNMLDPI
CCCEEEEECCCHHHHHHCCCCCHHHEEECCCCHHHHHHCCCCCCCCCCHHHCCCCHHHHH
KSTIVTPGLDLNGKFAKTGIPASIVTKFLAEHGVIVEKTGLYSFFIMFTIGITKGRWNTL
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHH
LTALQQFKDDYAKNQPMWRILPEFCQKYPKYERMGLADLCQHIHALYAKYDIARLTTEVY
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSDLAPVMKPSDAYAHIAHRTTERVEIDQLEGRITVGLVTPYPPGIPLLIPGEVFNKKIV
HHHHHHHCCCCHHHHHHHHHHHHHEEHHHCCCEEEEEEECCCCCCCCEEECHHHHHHHHH
DYLKFAREFNAQCPGFETDIHGLVEEVDAKGKVRYYADCVKKAR
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKFRFPIVIIDEDFRSENTSGLSIRALAQAIESEGFEVLGVTSYGDLSQFAQQQSRASAF
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEE
ILSIDDEEFTPGPDLDPAVLNLRNFIEEVRRKNLDVPIYVYGETKTSRHIPNDILRELHG
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHH
FIHMFEDTPEFVARHILREAKSYLEGVQPPFFKALLDYAEDGSYSWHCPGHSGGVAFLKS
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
PVGQMFHQFFGENMLRADVCNAVEELGQLLDHDGAIGASERNAARIFNADHCFFVTNGTS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEEECCCC
TSNKMVWHHTVAPGDVVVVDRNCHKSILHAIIMTGAIPVFLKPTRNHFGIIGPIPQSEFE
CCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCC
PEAIKAKIRANPLLKGVDADKVKPRVLTLTQSTYDGVLYNTETIKGMLDGYVDNLHFDEA
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHCCCCCCC
WLPHAAFHPFYGSYHAMGKNRIRPKNAVVYATQSIHKLLAGISQASHVLVQDSQNTKLDR
CCCCHHCCCCCCCHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCEEEEECCCCCHHHH
HLFNEAYLMHTSTSPQYSIIASCDVAAAMMEPPGGTALVEESIAEALDFRRAMRKIDDEY
HHHCCEEEEECCCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GSDWWFKVWGPDKLVEEGIGLAEDWIIKGESRSAKRAKNGANNWHGFGQMATGFNMLDPI
CCCEEEEECCCHHHHHHCCCCCHHHEEECCCCHHHHHHCCCCCCCCCCHHHCCCCHHHHH
KSTIVTPGLDLNGKFAKTGIPASIVTKFLAEHGVIVEKTGLYSFFIMFTIGITKGRWNTL
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHH
LTALQQFKDDYAKNQPMWRILPEFCQKYPKYERMGLADLCQHIHALYAKYDIARLTTEVY
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSDLAPVMKPSDAYAHIAHRTTERVEIDQLEGRITVGLVTPYPPGIPLLIPGEVFNKKIV
HHHHHHHCCCCHHHHHHHHHHHHHEEHHHCCCEEEEEEECCCCCCCCEEECHHHHHHHHH
DYLKFAREFNAQCPGFETDIHGLVEEVDAKGKVRYYADCVKKAR
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]