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The map label for this gene is rhtB [H]

Identifier: 91788260

GI number: 91788260

Start: 2488990

End: 2489622

Strand: Reverse

Name: rhtB [H]

Synonym: Bpro_2393

Alternate gene names: 91788260

Gene position: 2489622-2488990 (Counterclockwise)

Preceding gene: 91788261

Following gene: 91788259

Centisome position: 47.87

GC content: 65.24

Gene sequence:

>633_bases
ATGAACACGACCACCCTGTTGCTCTTTTCCCTCGTGGCACTGGTCGCCATTGCCACACCCGGCCCCACGGTGTTGCTGGC
GCTGGCCAATGGCTCGCATTACGGTGTGCGCCGTTCGCTGCCGGGCATGCTGGGTGCCGTGCTGTCGGATTTCGTACTCG
TGGGTGCGGTGGCGCTGGGCTTGGGCGCGCTGCTGGCGGCTTCGGAGTTCTGGTTTTCCGTGCTGAAGTGGGTGGGCGCG
GCCTACCTCGCCTGGCTGGGCATTCGCCTCTTGCGCTCAAAGAGCGGGTTTAATCTGCCTGCGCAGGGCGCAGCCACGGC
GCAGCACGGCCGCCGCGTGATTTTCATGAAGTCGTTTCTGGTGGCCGTGACCAACCCCAAGGGCTACCTGTTTTGCTCGG
CCCTGCTGCCGCAGTTCATTGACCCAGCCACCGCGCAGGCGCCGCAATACACGGCGATAGCCGTTGTCTTCGCCGGCATT
GATTTCTCGGTGATGCTGGGTTACGCCTTCATTGGCGCGCGCGCCATCCGCCTCTTCAAAGCCCGGGCCATCAAATGGCT
GGATCGCGCCTGCGGCGGCACCCTGTTGGCGCTGGCCGCATCGCTCGCGCTGTACCGCCGGGCCAACACCTGA

Upstream 100 bases:

>100_bases
GTGAGTTTGTCGCGAGGCCGCGCCGTCCGGCAGACCTGCTCGCCAAATATCCGCCCTCGACCCAACGCGTGTTCAAACCC
GACGGCTGTGGAGCGGCACC

Downstream 100 bases:

>100_bases
CCTTTCGGGTGGGCGGCAAGCTGTTGCTCCTGTTTTTATAGCCATTGACACCCGTTTCCTCTGGCGTACAGTCTTTATTG
TCAATAGCGCCACCTGGCGC

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MNTTTLLLFSLVALVAIATPGPTVLLALANGSHYGVRRSLPGMLGAVLSDFVLVGAVALGLGALLAASEFWFSVLKWVGA
AYLAWLGIRLLRSKSGFNLPAQGAATAQHGRRVIFMKSFLVAVTNPKGYLFCSALLPQFIDPATAQAPQYTAIAVVFAGI
DFSVMLGYAFIGARAIRLFKARAIKWLDRACGGTLLALAASLALYRRANT

Sequences:

>Translated_210_residues
MNTTTLLLFSLVALVAIATPGPTVLLALANGSHYGVRRSLPGMLGAVLSDFVLVGAVALGLGALLAASEFWFSVLKWVGA
AYLAWLGIRLLRSKSGFNLPAQGAATAQHGRRVIFMKSFLVAVTNPKGYLFCSALLPQFIDPATAQAPQYTAIAVVFAGI
DFSVMLGYAFIGARAIRLFKARAIKWLDRACGGTLLALAASLALYRRANT
>Mature_210_residues
MNTTTLLLFSLVALVAIATPGPTVLLALANGSHYGVRRSLPGMLGAVLSDFVLVGAVALGLGALLAASEFWFSVLKWVGA
AYLAWLGIRLLRSKSGFNLPAQGAATAQHGRRVIFMKSFLVAVTNPKGYLFCSALLPQFIDPATAQAPQYTAIAVVFAGI
DFSVMLGYAFIGARAIRLFKARAIKWLDRACGGTLLALAASLALYRRANT

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=204, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI1788099, Length=138, Percent_Identity=29.7101449275362, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22205; Mature: 22205

Theoretical pI: Translated: 11.12; Mature: 11.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTTLLLFSLVALVAIATPGPTVLLALANGSHYGVRRSLPGMLGAVLSDFVLVGAVALG
CCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGALLAASEFWFSVLKWVGAAYLAWLGIRLLRSKSGFNLPAQGAATAQHGRRVIFMKSFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCEEEEEHHHH
VAVTNPKGYLFCSALLPQFIDPATAQAPQYTAIAVVFAGIDFSVMLGYAFIGARAIRLFK
HHEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ARAIKWLDRACGGTLLALAASLALYRRANT
HHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTTTLLLFSLVALVAIATPGPTVLLALANGSHYGVRRSLPGMLGAVLSDFVLVGAVALG
CCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGALLAASEFWFSVLKWVGAAYLAWLGIRLLRSKSGFNLPAQGAATAQHGRRVIFMKSFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCEEEEEHHHH
VAVTNPKGYLFCSALLPQFIDPATAQAPQYTAIAVVFAGIDFSVMLGYAFIGARAIRLFK
HHEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ARAIKWLDRACGGTLLALAASLALYRRANT
HHHHHHHHHHHCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]