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The map label for this gene is chpE [H]

Identifier: 91788231

GI number: 91788231

Start: 2458004

End: 2458672

Strand: Reverse

Name: chpE [H]

Synonym: Bpro_2364

Alternate gene names: 91788231

Gene position: 2458672-2458004 (Counterclockwise)

Preceding gene: 91788232

Following gene: 91788230

Centisome position: 47.28

GC content: 62.63

Gene sequence:

>669_bases
ATGGCCGCACTCTTTATCTCCGCTTTCCTGCTCGGGCTTTTGTTCAACGCCGCGCCCGGCGCCGTGTTTGCCGAAACCGT
GCGCCAGGGCGTACGCGGCGGGTTCCGGCCTGCCCTTGCCGTGCAAATCGGATCGCTGGCTGGAGATGCGCTCTGGGCCC
TGTTGGGGCTGGCAGGCATAGGACTGCTCCTTCAATTGGAATGGATTCGCTGGCCCGTCGGCATAGCTGGGGCCGTGTAC
CTTTTCTGGCTTGCCCGCGACTCCTGGGTTTCCGCCAGCCAGGAGTTCTCTTTAACCGGCTCGGCGACGGTCGAGCCCAA
ACGGGCCATGCGTGCCGGCGTTCTCCTGTCCGTGACCAACCCGCAAAACATTGCCTATTGGGCCGCTCTGGGAAGCGCCC
TTGGGGCCATCGGCATCCATGAACCAAAGGCCTCCGACTACGCCATCTTCTTTTTGGGGTTCATGGTGTCGTCGGTGGTG
TGGGCTTTCTTCTGCGCGGCAGTTGTTGACAGAATCTTTCGCCGCGCAGGCACGCGGTGGGCCAAGGCCACCTACAAACT
GTGCGCCGCCGCGTTCCTGGCGCTGGCCCTCGGTTCGATGCGCGATCTCATTGTTCAGTTGTCGCCACTTCCGCAAAAAG
ACAAGCCCGCCATTGCCGGCAAGCCCTGA

Upstream 100 bases:

>100_bases
TTTGAGGGCGAGTTCGCGTGGCAGGTTGAGAAATTCAAGGAGCTGGCCGCGGCCTGCGCGGTATAAACGTCAGGTCTTCT
TTTTTTTTCACATCATCTTC

Downstream 100 bases:

>100_bases
ATCCTTGTAACCGGTTCCAACAGGAGAAACCATGCAACTCATCGGAATGCTTGACTCACCTTACGTTCGCCGCGTGGCTA
TTTCCCTGCAGCTTCTCGGT

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MAALFISAFLLGLLFNAAPGAVFAETVRQGVRGGFRPALAVQIGSLAGDALWALLGLAGIGLLLQLEWIRWPVGIAGAVY
LFWLARDSWVSASQEFSLTGSATVEPKRAMRAGVLLSVTNPQNIAYWAALGSALGAIGIHEPKASDYAIFFLGFMVSSVV
WAFFCAAVVDRIFRRAGTRWAKATYKLCAAAFLALALGSMRDLIVQLSPLPQKDKPAIAGKP

Sequences:

>Translated_222_residues
MAALFISAFLLGLLFNAAPGAVFAETVRQGVRGGFRPALAVQIGSLAGDALWALLGLAGIGLLLQLEWIRWPVGIAGAVY
LFWLARDSWVSASQEFSLTGSATVEPKRAMRAGVLLSVTNPQNIAYWAALGSALGAIGIHEPKASDYAIFFLGFMVSSVV
WAFFCAAVVDRIFRRAGTRWAKATYKLCAAAFLALALGSMRDLIVQLSPLPQKDKPAIAGKP
>Mature_221_residues
AALFISAFLLGLLFNAAPGAVFAETVRQGVRGGFRPALAVQIGSLAGDALWALLGLAGIGLLLQLEWIRWPVGIAGAVYL
FWLARDSWVSASQEFSLTGSATVEPKRAMRAGVLLSVTNPQNIAYWAALGSALGAIGIHEPKASDYAIFFLGFMVSSVVW
AFFCAAVVDRIFRRAGTRWAKATYKLCAAAFLALALGSMRDLIVQLSPLPQKDKPAIAGKP

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23613; Mature: 23482

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALFISAFLLGLLFNAAPGAVFAETVRQGVRGGFRPALAVQIGSLAGDALWALLGLAGI
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLLLQLEWIRWPVGIAGAVYLFWLARDSWVSASQEFSLTGSATVEPKRAMRAGVLLSVTN
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHCCEEEEECC
PQNIAYWAALGSALGAIGIHEPKASDYAIFFLGFMVSSVVWAFFCAAVVDRIFRRAGTRW
CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AKATYKLCAAAFLALALGSMRDLIVQLSPLPQKDKPAIAGKP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AALFISAFLLGLLFNAAPGAVFAETVRQGVRGGFRPALAVQIGSLAGDALWALLGLAGI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLLLQLEWIRWPVGIAGAVYLFWLARDSWVSASQEFSLTGSATVEPKRAMRAGVLLSVTN
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHCCEEEEECC
PQNIAYWAALGSALGAIGIHEPKASDYAIFFLGFMVSSVVWAFFCAAVVDRIFRRAGTRW
CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AKATYKLCAAAFLALALGSMRDLIVQLSPLPQKDKPAIAGKP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]