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The map label for this gene is moaE [H]

Identifier: 91788069

GI number: 91788069

Start: 2291743

End: 2292309

Strand: Direct

Name: moaE [H]

Synonym: Bpro_2196

Alternate gene names: 91788069

Gene position: 2291743-2292309 (Clockwise)

Preceding gene: 91788067

Following gene: 91788071

Centisome position: 44.07

GC content: 61.02

Gene sequence:

>567_bases
ATGGCTCTATCCCGCGTTCTGATCACGACCGAAGACTTCAACCTGGCCGATGAGGTGGCTGTTCTGCGCGCGAATGACAG
CCGGGTCGGCGCCGTATGCACTTTCACGGGCACCGTGAGGGACCGCAATATGGCCCCCACACTTGCCACTGCGTGTGCTG
CGCTGCCCCCCGAGGGGGCTGAACTTGCTAGGGGCGGCCCGTCGCTGCGTTCGTCGGCCCAGCAAGGGGAGGTGCTTTCG
ATGGAACTGGAACACTACCCCGGCATGACCGAAAAAGCCATTGAGGCCATGATCGACGAGGCGATGGTGCGCTTCGATAT
TTTTGGCGTTCGGGTGATCCACCGTGTCGGACTTTTGCAGCCGCTGGATCAGGTGGTCATGGTGGCGGTGACTTCCGCTC
ACCGCGGTGAAAGCTTCAAGGCCTGTGAATTTTTGATGGACTACCTGAAAACCCAGGCGCCGTTCTGGAAAAAAGAGCAG
ACGCCAGAGGGCGCGCGCTGGGTCGATGCGCGCGTGAGCGACGATGCCGCACTGGCCAAATGGGGCATACAAGCCACCAA
TGGCTAG

Upstream 100 bases:

>100_bases
CGTTGGGCATCCAGGCGGTGAGGAGGTTTGTGCAGCCAGTCATGCGACAAATCTTACGGTATGTATCCGGCTTTTGGGGG
CTGGTGGCAAAATTGCAACT

Downstream 100 bases:

>100_bases
TACTTCTGGGTCGGAGTACCAAACATTACTTCGCCCCCGGCATACCCCTGGGCTCGTCCGTATCTTGCGCTGGAGGCACA
AAAGGGGCCCGCGCCTCGTC

Product: molybdopterin synthase subunit MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MALSRVLITTEDFNLADEVAVLRANDSRVGAVCTFTGTVRDRNMAPTLATACAALPPEGAELARGGPSLRSSAQQGEVLS
MELEHYPGMTEKAIEAMIDEAMVRFDIFGVRVIHRVGLLQPLDQVVMVAVTSAHRGESFKACEFLMDYLKTQAPFWKKEQ
TPEGARWVDARVSDDAALAKWGIQATNG

Sequences:

>Translated_188_residues
MALSRVLITTEDFNLADEVAVLRANDSRVGAVCTFTGTVRDRNMAPTLATACAALPPEGAELARGGPSLRSSAQQGEVLS
MELEHYPGMTEKAIEAMIDEAMVRFDIFGVRVIHRVGLLQPLDQVVMVAVTSAHRGESFKACEFLMDYLKTQAPFWKKEQ
TPEGARWVDARVSDDAALAKWGIQATNG
>Mature_187_residues
ALSRVLITTEDFNLADEVAVLRANDSRVGAVCTFTGTVRDRNMAPTLATACAALPPEGAELARGGPSLRSSAQQGEVLSM
ELEHYPGMTEKAIEAMIDEAMVRFDIFGVRVIHRVGLLQPLDQVVMVAVTSAHRGESFKACEFLMDYLKTQAPFWKKEQT
PEGARWVDARVSDDAALAKWGIQATNG

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=98, Percent_Identity=31.6326530612245, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1787003, Length=181, Percent_Identity=42.5414364640884, Blast_Score=147, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 20469; Mature: 20337

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSRVLITTEDFNLADEVAVLRANDSRVGAVCTFTGTVRDRNMAPTLATACAALPPEGA
CCCCEEEEEECCCCCHHHEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCH
ELARGGPSLRSSAQQGEVLSMELEHYPGMTEKAIEAMIDEAMVRFDIFGVRVIHRVGLLQ
HHHCCCCHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLDQVVMVAVTSAHRGESFKACEFLMDYLKTQAPFWKKEQTPEGARWVDARVSDDAALAK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHH
WGIQATNG
CCCEECCC
>Mature Secondary Structure 
ALSRVLITTEDFNLADEVAVLRANDSRVGAVCTFTGTVRDRNMAPTLATACAALPPEGA
CCCEEEEEECCCCCHHHEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCH
ELARGGPSLRSSAQQGEVLSMELEHYPGMTEKAIEAMIDEAMVRFDIFGVRVIHRVGLLQ
HHHCCCCHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLDQVVMVAVTSAHRGESFKACEFLMDYLKTQAPFWKKEQTPEGARWVDARVSDDAALAK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHH
WGIQATNG
CCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]