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The map label for this gene is moeA [H]

Identifier: 91788066

GI number: 91788066

Start: 2289018

End: 2290292

Strand: Direct

Name: moeA [H]

Synonym: Bpro_2193

Alternate gene names: 91788066

Gene position: 2289018-2290292 (Clockwise)

Preceding gene: 91788065

Following gene: 91788067

Centisome position: 44.02

GC content: 66.12

Gene sequence:

>1275_bases
ATGAACACCTCCCGAGCCACCCCTACATCCAGCCCCGCTGCACCAGCTGCCCGTCCCGCGCTCAGGCCGCTTGACGACGC
GCTGGCCGAACTGCTGACCCCAGCCCTGCCGCTGGCTGGCCCGGAAACGGTCTCGACGTTCGAGGCCGATGGCCGCGTGC
TGGCCGAAGATGTGGTTTCCGCGCTGCAGGTGCCGCCCGAAGACAACAGCTCGATGGACGGATACGCCGTGCGCGCAGCT
GAAGTACAGCACGCCGGCACGGCTTTGCGTGTGTCGCAACGCATTCCCGCCGGCAGTGCAGGCAGTGCGCTGGAGCCGGG
CACGGCCGCGCGCATCTTCACCGGCGCGCCTATCCCGGCCGGGGCCGACGCGGTGGTGATGCAGGAAGACTGCGAAGTGC
TGGCGGACCCGCAAGGTTTTATCCGCATCACGCAGGCGCCCAAACCCGCGCAGTGGATTCGCCGTGCCGGCGAGGATGTC
ATGCGCGGCGCCGTCGTGCTATCAAAAGGGGAACGACTAACGCCTGCCGCACTTGGGCTGGCAGCCGGTATTGGCAGGAA
TTTTCTGCAAGTGGCACGTCGGCCGCGGGTGGCACTGTTTTCCACCGGCGATGAGCTGGTCATGCCCGGCGAAGTTGCTC
CAGAGCAGATGCGGCCGGGCGCCATCTACAACTCCAACCGCTTCTTCCTGCGCGCCTTGCTGTCGCGTCTGGGCTGCGAG
GTGACCGACATGGGCATCGTGCCGGACCGGCGCGATGCCACGCTGGACGCGCTGCGCAGCGCCAGCCAGGCGCACGATTT
GATCCTGACCAGCGGCGGCGTGTCTGTCGGTGAAGAAGATCACATCAAGCCTGCGGTGCAGCAGCTTGGGTCACTCGATC
TCTGGCAGATCGCGATCAAGCCGGGCAAGCCGTTTGCCTATGGCAAGGTCGGGCCGGCGCACTTCATCGGCCTGCCGGGC
AACCCTGTTTCCAGCTTCGTGACCTTCCTGCTACTGGTGCGGCCCTTTCTGCTCAAGCTGCAGGGTGCGAGCCAGGTGGC
CATGAAATCAGTCACTGTTCCCGCTCATTTCAGCTGGCCCAGGGCCGACAAGCGCCGCGAGTTCCTGCGGGTGCGACGCA
ATGCTGCCGGCGGGCTGGACCTGTTTGCCAATCAGAGTTCTGGCGTACTGACCTCGGCGGTCTGGGGCGACGGCCTGGTG
GACAACCCGGCGGGGCAGACCATCGCGCACGGCGACAGCGTACAGTTCATCCCGTTTTCGGAGCTTCTCTCGTGA

Upstream 100 bases:

>100_bases
CCACCCTCAGGCCGGTGCTGGATTTGAACGATGTTGATGCCCTGGCGCAGTGGTTGATTGACAATCAGGAACGCTTTGCC
TACCGCCCCGAGTCGTATGC

Downstream 100 bases:

>100_bases
AAGCCCATTCATGAAAGTCACGGTCAGGTATTTTGCGTCCATCCGTGAGGCCATCGGGCGGGGTAGCGAGTTGCGCGAAA
CCGCCGCCGGCACGCTGGCG

Product: MoeA-like proteindomain-containing protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MNTSRATPTSSPAAPAARPALRPLDDALAELLTPALPLAGPETVSTFEADGRVLAEDVVSALQVPPEDNSSMDGYAVRAA
EVQHAGTALRVSQRIPAGSAGSALEPGTAARIFTGAPIPAGADAVVMQEDCEVLADPQGFIRITQAPKPAQWIRRAGEDV
MRGAVVLSKGERLTPAALGLAAGIGRNFLQVARRPRVALFSTGDELVMPGEVAPEQMRPGAIYNSNRFFLRALLSRLGCE
VTDMGIVPDRRDATLDALRSASQAHDLILTSGGVSVGEEDHIKPAVQQLGSLDLWQIAIKPGKPFAYGKVGPAHFIGLPG
NPVSSFVTFLLLVRPFLLKLQGASQVAMKSVTVPAHFSWPRADKRREFLRVRRNAAGGLDLFANQSSGVLTSAVWGDGLV
DNPAGQTIAHGDSVQFIPFSELLS

Sequences:

>Translated_424_residues
MNTSRATPTSSPAAPAARPALRPLDDALAELLTPALPLAGPETVSTFEADGRVLAEDVVSALQVPPEDNSSMDGYAVRAA
EVQHAGTALRVSQRIPAGSAGSALEPGTAARIFTGAPIPAGADAVVMQEDCEVLADPQGFIRITQAPKPAQWIRRAGEDV
MRGAVVLSKGERLTPAALGLAAGIGRNFLQVARRPRVALFSTGDELVMPGEVAPEQMRPGAIYNSNRFFLRALLSRLGCE
VTDMGIVPDRRDATLDALRSASQAHDLILTSGGVSVGEEDHIKPAVQQLGSLDLWQIAIKPGKPFAYGKVGPAHFIGLPG
NPVSSFVTFLLLVRPFLLKLQGASQVAMKSVTVPAHFSWPRADKRREFLRVRRNAAGGLDLFANQSSGVLTSAVWGDGLV
DNPAGQTIAHGDSVQFIPFSELLS
>Mature_424_residues
MNTSRATPTSSPAAPAARPALRPLDDALAELLTPALPLAGPETVSTFEADGRVLAEDVVSALQVPPEDNSSMDGYAVRAA
EVQHAGTALRVSQRIPAGSAGSALEPGTAARIFTGAPIPAGADAVVMQEDCEVLADPQGFIRITQAPKPAQWIRRAGEDV
MRGAVVLSKGERLTPAALGLAAGIGRNFLQVARRPRVALFSTGDELVMPGEVAPEQMRPGAIYNSNRFFLRALLSRLGCE
VTDMGIVPDRRDATLDALRSASQAHDLILTSGGVSVGEEDHIKPAVQQLGSLDLWQIAIKPGKPFAYGKVGPAHFIGLPG
NPVSSFVTFLLLVRPFLLKLQGASQVAMKSVTVPAHFSWPRADKRREFLRVRRNAAGGLDLFANQSSGVLTSAVWGDGLV
DNPAGQTIAHGDSVQFIPFSELLS

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=333, Percent_Identity=37.2372372372372, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI66932975, Length=333, Percent_Identity=37.2372372372372, Blast_Score=182, Evalue=4e-46,
Organism=Escherichia coli, GI1787049, Length=386, Percent_Identity=42.7461139896373, Blast_Score=266, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI25147659, Length=347, Percent_Identity=31.9884726224784, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17562606, Length=369, Percent_Identity=25.7452574525745, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17136978, Length=365, Percent_Identity=32.3287671232877, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24638841, Length=365, Percent_Identity=32.3287671232877, Blast_Score=141, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 44719; Mature: 44719

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSRATPTSSPAAPAARPALRPLDDALAELLTPALPLAGPETVSTFEADGRVLAEDVVS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHEECCCCCHHHHHHHH
ALQVPPEDNSSMDGYAVRAAEVQHAGTALRVSQRIPAGSAGSALEPGTAARIFTGAPIPA
HHCCCCCCCCCCCCEEEEHHHHHHCCCCEEHHHCCCCCCCCCCCCCCCCEEEEECCCCCC
GADAVVMQEDCEVLADPQGFIRITQAPKPAQWIRRAGEDVMRGAVVLSKGERLTPAALGL
CCCEEEEECCCHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHH
AAGIGRNFLQVARRPRVALFSTGDELVMPGEVAPEQMRPGAIYNSNRFFLRALLSRLGCE
HHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHCCCCCEECCCHHHHHHHHHHHCCC
VTDMGIVPDRRDATLDALRSASQAHDLILTSGGVSVGEEDHIKPAVQQLGSLDLWQIAIK
EEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHCCCCEEEEEEC
PGKPFAYGKVGPAHFIGLPGNPVSSFVTFLLLVRPFLLKLQGASQVAMKSVTVPAHFSWP
CCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCCC
RADKRREFLRVRRNAAGGLDLFANQSSGVLTSAVWGDGLVDNPAGQTIAHGDSVQFIPFS
CHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCEEECCCCEEEECHH
ELLS
HHHC
>Mature Secondary Structure
MNTSRATPTSSPAAPAARPALRPLDDALAELLTPALPLAGPETVSTFEADGRVLAEDVVS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHEECCCCCHHHHHHHH
ALQVPPEDNSSMDGYAVRAAEVQHAGTALRVSQRIPAGSAGSALEPGTAARIFTGAPIPA
HHCCCCCCCCCCCCEEEEHHHHHHCCCCEEHHHCCCCCCCCCCCCCCCCEEEEECCCCCC
GADAVVMQEDCEVLADPQGFIRITQAPKPAQWIRRAGEDVMRGAVVLSKGERLTPAALGL
CCCEEEEECCCHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHH
AAGIGRNFLQVARRPRVALFSTGDELVMPGEVAPEQMRPGAIYNSNRFFLRALLSRLGCE
HHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHCCCCCEECCCHHHHHHHHHHHCCC
VTDMGIVPDRRDATLDALRSASQAHDLILTSGGVSVGEEDHIKPAVQQLGSLDLWQIAIK
EEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHCCCCEEEEEEC
PGKPFAYGKVGPAHFIGLPGNPVSSFVTFLLLVRPFLLKLQGASQVAMKSVTVPAHFSWP
CCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCCC
RADKRREFLRVRRNAAGGLDLFANQSSGVLTSAVWGDGLVDNPAGQTIAHGDSVQFIPFS
CHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCEEECCCCEEEECHH
ELLS
HHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]