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The map label for this gene is yfbQ [H]

Identifier: 91788062

GI number: 91788062

Start: 2284292

End: 2285515

Strand: Direct

Name: yfbQ [H]

Synonym: Bpro_2189

Alternate gene names: 91788062

Gene position: 2284292-2285515 (Clockwise)

Preceding gene: 91788057

Following gene: 91788063

Centisome position: 43.93

GC content: 59.64

Gene sequence:

>1224_bases
ATGAAACCGATCACTAAATCTGCCAAATTGGCCAACGTGCTCTACGACATCCGCGGCCCCATCATGGACGCCGCCAAGCA
GATGGAAGAAGAAGGGCACCATCTCATCAAGCTCAACCTGGGCAATCTGGCAGTGTTCGGTTTCGATGCGCCCGAGGAAA
TCCAGCAGGACATGATCCGCAACCTGCCCTCGTCTGCCGGCTATTCAGACAGCAAGGGTATTTTTGCGGCGCGCAAGGCG
GTGATGCACGAGACCCAGAAGCAGGGCATCAGCGGCGTGACGCTCGATGATATTTACCTGGGCAATGGCGCCAGCGAGTT
GATCGCGATGGCCACCAACGCGCTGCTCGACGACGGCGATGAACTACTGCTGCCGACGCCTGACTATCCGCTATGGACCG
CCTCCACCAGCCTGTCGGGCGGCAAACCGGTGCACTATCTCTGCGATGAGGACAACGGCTGGATGCCCAACCTTGACGAT
ATTCGCGCCAAGATTACGCCCAAGACCAAGGGCATTGTGGTCATCAATCCAAACAACCCGACTGGCGCGCTGTATTCCGA
CGAACTTCTCAAGCAGATCGTGGAGATCGCCCGCACCCATGGCCTGGTGATTCTGGCCGATGAGGTCTACGACAAGGTGC
TGTATGACGGGGCCCACCATACCGCCATCGCCAGCCTGTCGACGGACGTGCTCACGCTGACTTTCAATTCGCTGTCCAAG
AGCTACCGCTCCTGCGGCTATCGCGCAGGCTGGCTGGTGGTGTCCGGCCCCAAGAAGCGGGCGGAGGACTACATCGAGGG
CCTCAACATGCTGGCCAACATGAAGCTGTGCTCCAACGTGCCGGGCCAATGGGCCATCCAGACGGCCCTGGGTGGCTACC
AGAGCATCAACGACCTGACGGGCGAGGGCGGGCGTCTGCGGCGCCAGCGCGATCTGGCGTACGAACTGATCACCGCCATC
CCGGGGGTGAGCTGCGTGAAGCCGAGCGCTGCCCTCTACATGTTCCCCAAGCTCGATCCGAAGGTTTATCCGATCAAGGA
CGACCGGCAGTTCTTCCTCGAGCTGCTCAAGGAAACCAAGGTGATGCTGGTGCAGGGCACCGGCTTCAACTGGGCATCGC
CGGATCACTTTCGCATCGTCTTTCTGCCCCATGAGGAAGATCTGCGCGAGGCCGTGGGCCGGATTGCAAAATTCCTCGAG
AATTATCGAAACAACAACATCTGA

Upstream 100 bases:

>100_bases
GCCCGAATTTCCCGTTTTCGCACTGACCTTGCCCCGCCTGCCAGTGTGTTTGTCGGCCTGTTTGACGGTGTGGCCCCGGC
CGCCTATCCCACAATGCAAC

Downstream 100 bases:

>100_bases
GCCGGTACTGGCAAGGACTGCAGATATTTTTGACTATTGAGCAACATGAAACCGAAATCGACAAATCTCAAATCCATCCA
GGTCGGCTTGCTGGGCATAG

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKPITKSAKLANVLYDIRGPIMDAAKQMEEEGHHLIKLNLGNLAVFGFDAPEEIQQDMIRNLPSSAGYSDSKGIFAARKA
VMHETQKQGISGVTLDDIYLGNGASELIAMATNALLDDGDELLLPTPDYPLWTASTSLSGGKPVHYLCDEDNGWMPNLDD
IRAKITPKTKGIVVINPNNPTGALYSDELLKQIVEIARTHGLVILADEVYDKVLYDGAHHTAIASLSTDVLTLTFNSLSK
SYRSCGYRAGWLVVSGPKKRAEDYIEGLNMLANMKLCSNVPGQWAIQTALGGYQSINDLTGEGGRLRRQRDLAYELITAI
PGVSCVKPSAALYMFPKLDPKVYPIKDDRQFFLELLKETKVMLVQGTGFNWASPDHFRIVFLPHEEDLREAVGRIAKFLE
NYRNNNI

Sequences:

>Translated_407_residues
MKPITKSAKLANVLYDIRGPIMDAAKQMEEEGHHLIKLNLGNLAVFGFDAPEEIQQDMIRNLPSSAGYSDSKGIFAARKA
VMHETQKQGISGVTLDDIYLGNGASELIAMATNALLDDGDELLLPTPDYPLWTASTSLSGGKPVHYLCDEDNGWMPNLDD
IRAKITPKTKGIVVINPNNPTGALYSDELLKQIVEIARTHGLVILADEVYDKVLYDGAHHTAIASLSTDVLTLTFNSLSK
SYRSCGYRAGWLVVSGPKKRAEDYIEGLNMLANMKLCSNVPGQWAIQTALGGYQSINDLTGEGGRLRRQRDLAYELITAI
PGVSCVKPSAALYMFPKLDPKVYPIKDDRQFFLELLKETKVMLVQGTGFNWASPDHFRIVFLPHEEDLREAVGRIAKFLE
NYRNNNI
>Mature_407_residues
MKPITKSAKLANVLYDIRGPIMDAAKQMEEEGHHLIKLNLGNLAVFGFDAPEEIQQDMIRNLPSSAGYSDSKGIFAARKA
VMHETQKQGISGVTLDDIYLGNGASELIAMATNALLDDGDELLLPTPDYPLWTASTSLSGGKPVHYLCDEDNGWMPNLDD
IRAKITPKTKGIVVINPNNPTGALYSDELLKQIVEIARTHGLVILADEVYDKVLYDGAHHTAIASLSTDVLTLTFNSLSK
SYRSCGYRAGWLVVSGPKKRAEDYIEGLNMLANMKLCSNVPGQWAIQTALGGYQSINDLTGEGGRLRRQRDLAYELITAI
PGVSCVKPSAALYMFPKLDPKVYPIKDDRQFFLELLKETKVMLVQGTGFNWASPDHFRIVFLPHEEDLREAVGRIAKFLE
NYRNNNI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=468, Percent_Identity=27.5641025641026, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI215599424, Length=396, Percent_Identity=29.040404040404, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI4507369, Length=390, Percent_Identity=27.9487179487179, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4885351, Length=444, Percent_Identity=25.2252252252252, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI95147551, Length=170, Percent_Identity=30, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI169881279, Length=170, Percent_Identity=30, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI169881281, Length=147, Percent_Identity=29.9319727891156, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI56713254, Length=171, Percent_Identity=28.0701754385965, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI56713256, Length=171, Percent_Identity=28.0701754385965, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI187936925, Length=375, Percent_Identity=24.5333333333333, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI14211921, Length=375, Percent_Identity=24.5333333333333, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=62.6237623762376, Blast_Score=548, Evalue=1e-157,
Organism=Escherichia coli, GI1788722, Length=402, Percent_Identity=25.8706467661692, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786816, Length=385, Percent_Identity=22.5974025974026, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790797, Length=357, Percent_Identity=24.9299719887955, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=416, Percent_Identity=29.5673076923077, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI71981209, Length=467, Percent_Identity=26.5524625267666, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=233, Percent_Identity=30.4721030042918, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=233, Percent_Identity=30.4721030042918, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=215, Percent_Identity=26.9767441860465, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71981215, Length=295, Percent_Identity=26.4406779661017, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=406, Percent_Identity=29.8029556650246, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323118, Length=383, Percent_Identity=29.242819843342, Blast_Score=143, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6322401, Length=401, Percent_Identity=25.6857855361596, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI18859735, Length=374, Percent_Identity=29.6791443850267, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI45551451, Length=473, Percent_Identity=24.7357293868922, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641770, Length=473, Percent_Identity=24.7357293868922, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641760, Length=473, Percent_Identity=24.7357293868922, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641768, Length=473, Percent_Identity=24.7357293868922, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641766, Length=473, Percent_Identity=24.7357293868922, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24641764, Length=473, Percent_Identity=24.7357293868922, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573069, Length=166, Percent_Identity=27.710843373494, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646114, Length=166, Percent_Identity=27.710843373494, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573067, Length=166, Percent_Identity=27.710843373494, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573065, Length=166, Percent_Identity=27.710843373494, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 44987; Mature: 44987

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPITKSAKLANVLYDIRGPIMDAAKQMEEEGHHLIKLNLGNLAVFGFDAPEEIQQDMIR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEEECCCHHHHHHHHHH
NLPSSAGYSDSKGIFAARKAVMHETQKQGISGVTLDDIYLGNGASELIAMATNALLDDGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
ELLLPTPDYPLWTASTSLSGGKPVHYLCDEDNGWMPNLDDIRAKITPKTKGIVVINPNNP
EEEECCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGALYSDELLKQIVEIARTHGLVILADEVYDKVLYDGAHHTAIASLSTDVLTLTFNSLSK
CCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCHHHHHHCCCCEEEEEHHHHHH
SYRSCGYRAGWLVVSGPKKRAEDYIEGLNMLANMKLCSNVPGQWAIQTALGGYQSINDLT
HHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHHHHHC
GEGGRLRRQRDLAYELITAIPGVSCVKPSAALYMFPKLDPKVYPIKDDRQFFLELLKETK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHCCC
VMLVQGTGFNWASPDHFRIVFLPHEEDLREAVGRIAKFLENYRNNNI
EEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKPITKSAKLANVLYDIRGPIMDAAKQMEEEGHHLIKLNLGNLAVFGFDAPEEIQQDMIR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEEECCCHHHHHHHHHH
NLPSSAGYSDSKGIFAARKAVMHETQKQGISGVTLDDIYLGNGASELIAMATNALLDDGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
ELLLPTPDYPLWTASTSLSGGKPVHYLCDEDNGWMPNLDDIRAKITPKTKGIVVINPNNP
EEEECCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGALYSDELLKQIVEIARTHGLVILADEVYDKVLYDGAHHTAIASLSTDVLTLTFNSLSK
CCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCHHHHHHCCCCEEEEEHHHHHH
SYRSCGYRAGWLVVSGPKKRAEDYIEGLNMLANMKLCSNVPGQWAIQTALGGYQSINDLT
HHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHHHHHC
GEGGRLRRQRDLAYELITAIPGVSCVKPSAALYMFPKLDPKVYPIKDDRQFFLELLKETK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHCCC
VMLVQGTGFNWASPDHFRIVFLPHEEDLREAVGRIAKFLENYRNNNI
EEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]