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The map label for this gene is hscB [H]

Identifier: 91788054

GI number: 91788054

Start: 2276457

End: 2276975

Strand: Direct

Name: hscB [H]

Synonym: Bpro_2181

Alternate gene names: 91788054

Gene position: 2276457-2276975 (Clockwise)

Preceding gene: 91788053

Following gene: 161936270

Centisome position: 43.78

GC content: 56.26

Gene sequence:

>519_bases
ATGAACCTTCACTCCACCGATTTCGAACTGTTTGGCGTGCCTGTGCAGTTTGCGCAGGATCGTGCCGTGCTTGATGCTCG
CTGGAAAGAGCTGCAGCGTGAGGCACATCCGGACAAGTTTGCAGTCCAGGGCGCGGCCGCCCAGCGTGTGGCCATGCAAT
GGTCGGTACGCATCAATGAGGCTTACCAGCGGCTCAGGGATCCCTTGAAGCGCGCCAGCTACCTGCGCGAGTTGCATGGG
GCTCCGATCCAGGCCGAAAAAAATACGGCCATGCCACACGATTTTCTGGTCCAGCAAATGCAGTTGCGTGAAGCGCTGGA
TGAAGCCCAAACCGTTGAGGATCTGGAGGATATTGCCTCCGAGTCCCTATTGACTGCGGAAAAGCAGCTATCAAAAATAG
AGCGCGCTCTTGACATCAACAAGGACTTTGCCACTGCGGCGCAGCAGGTCAGAAGCCTTATGTTTATTGAGCGTTTTGCC
AGCGAGGTGGATGCGCGCATCGACCAGCTGGGACAATGA

Upstream 100 bases:

>100_bases
CTTTCGCGTTTGACGGGCGCACTTGCGCTAGCCCCGACATCCAGTACAGCCGTTTTTGCAGAGCCGCCTTCACTGACTGT
GCTGGCGGCTTTTTCTTGAC

Downstream 100 bases:

>100_bases
AGAATCATCCGAAGAACGACATGGCACTCCTGCAGATATCCGAACCCGGCCAGACGCCAGATCCGCACCAGCGGCGCATT
GCCGTTGGCATCGACCTGGG

Product: co-chaperone Hsc20

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MNLHSTDFELFGVPVQFAQDRAVLDARWKELQREAHPDKFAVQGAAAQRVAMQWSVRINEAYQRLRDPLKRASYLRELHG
APIQAEKNTAMPHDFLVQQMQLREALDEAQTVEDLEDIASESLLTAEKQLSKIERALDINKDFATAAQQVRSLMFIERFA
SEVDARIDQLGQ

Sequences:

>Translated_172_residues
MNLHSTDFELFGVPVQFAQDRAVLDARWKELQREAHPDKFAVQGAAAQRVAMQWSVRINEAYQRLRDPLKRASYLRELHG
APIQAEKNTAMPHDFLVQQMQLREALDEAQTVEDLEDIASESLLTAEKQLSKIERALDINKDFATAAQQVRSLMFIERFA
SEVDARIDQLGQ
>Mature_172_residues
MNLHSTDFELFGVPVQFAQDRAVLDARWKELQREAHPDKFAVQGAAAQRVAMQWSVRINEAYQRLRDPLKRASYLRELHG
APIQAEKNTAMPHDFLVQQMQLREALDEAQTVEDLEDIASESLLTAEKQLSKIERALDINKDFATAAQQVRSLMFIERFA
SEVDARIDQLGQ

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=122, Percent_Identity=32.7868852459016, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1788876, Length=158, Percent_Identity=38.6075949367089, Blast_Score=101, Evalue=2e-23,
Organism=Drosophila melanogaster, GI161084223, Length=149, Percent_Identity=26.8456375838926, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19692; Mature: 19692

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHSTDFELFGVPVQFAQDRAVLDARWKELQREAHPDKFAVQGAAAQRVAMQWSVRINE
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AYQRLRDPLKRASYLRELHGAPIQAEKNTAMPHDFLVQQMQLREALDEAQTVEDLEDIAS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLLTAEKQLSKIERALDINKDFATAAQQVRSLMFIERFASEVDARIDQLGQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLHSTDFELFGVPVQFAQDRAVLDARWKELQREAHPDKFAVQGAAAQRVAMQWSVRINE
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AYQRLRDPLKRASYLRELHGAPIQAEKNTAMPHDFLVQQMQLREALDEAQTVEDLEDIAS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLLTAEKQLSKIERALDINKDFATAAQQVRSLMFIERFASEVDARIDQLGQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA