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The map label for this gene is aspC [H]

Identifier: 91788048

GI number: 91788048

Start: 2269949

End: 2271145

Strand: Reverse

Name: aspC [H]

Synonym: Bpro_2175

Alternate gene names: 91788048

Gene position: 2271145-2269949 (Counterclockwise)

Preceding gene: 91788058

Following gene: 91788046

Centisome position: 43.67

GC content: 61.15

Gene sequence:

>1197_bases
ATGTCTTTGTTTACCGCTGTCGAAATGGCCCCGCGCGATCCGATTCTGGGTCTGAACGAGCAGTTCAATGCCGACACCAA
CCCGGCCAAAGTCAACCTCGGCGTGGGCGTTTATTTTGACGATAACGGCAAGCTGCCCCTGTTGCAATGCGTGCAGGCCG
CTGAAAAAACCATGATGGCCACGCCCTCGCCGCGTGGTTACCTGCCGATTGACGGAATTGCCGCCTATGACGCGGCTGTC
AAGGGCCTGGTGTTTGGCGCTGACAGCGAACCCGTCACTTCCGGCCGCATTGCCACCGTCCAGGGCATTGGCGGCACCGG
TGGCCTGAAGATAGGCGCAGACTTCCTCAAACACCTCAACCCCAACGCCAAGGTGCTGATCAGCGACCCGAGCTGGGAAA
ACCACCGTGCCCTGTTCACCAATGCAGGCTTCACGGTCGACAGCTACGCCTACTACGATGCAGCCAAACGTGGCGTGAAC
TTTGACGGCATGCTGGCCAGCCTGAACGCCGCCGAGCCCGGCACCATCGTCGTGCTGCACGCCTGCTGCCACAACCCGAC
CGGCTACGACATCACCGCCGCCCAGTGGGACCAGGTGATTGCCGCCGTCAAGGCCAAAGACCTCGTCGCCTTCCTCGACA
TGGCCTACCAGGGCTTTGGCCATGGAATTGCCGAAGACGGCGCGGTCATCGGCAAATTTGTGGCTGCGGGCCTGGACTTC
TTTGTCTCGACCTCGTTCTCCAAGAGCTTCAGCCTGTACGGCGAACGCGTGGGCGCCTTGAGCGTGCTGTGCGAGAGCAA
GGAAGAAGCAGCCCGCGTGCTGAGCCAGCTCAAGATCGTGATCCGCACCAATTATTCCAACCCGCCCATCCATGGCGGTG
CGGTGGTCGCTGCGGTGCTGAACAACCCCGAGCTGCACGCCCTGTGGGAACAGGAACTGGGCGAGATGCGTGTGCGCATC
AAGGCCATGCGCCAGAAACTGGTCGATGGCCTGAAGGCCGCCGGTGTCAAGCAGGACATGAGCTTTATCACCACCCAGAT
CGGCATGTTCAGCTACTCGGGCCTGTCCAAAGACCAGATGGTGCGCCTGCGCAACGAGTTTGGCGTGTACGGCACCGACA
CCGGCCGCATGTGCGTGGCGGCGCTGAACAGCAAAAACATCGACTACGTCTGCGCCTCCATCGCGAAGGTGATGTAA

Upstream 100 bases:

>100_bases
CTCCGCAGTAACACCCCGTAAAACCGGCCTGCCTGCATTGATTGCTTCTTCCGCTCTCTTCCGCTGATTCTTTCTTTCAT
TACTTCCTGAGGATTTTTTC

Downstream 100 bases:

>100_bases
GACTGGCGCCGCCCAGGCCCTAGCCCCAGACCACCGAACGCATCGAGATCGAGCCGCCCTGAAAGCTGGTGTTGAAAAAC
CGCATCGGCTCCCGGGCCTC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSLFTAVEMAPRDPILGLNEQFNADTNPAKVNLGVGVYFDDNGKLPLLQCVQAAEKTMMATPSPRGYLPIDGIAAYDAAV
KGLVFGADSEPVTSGRIATVQGIGGTGGLKIGADFLKHLNPNAKVLISDPSWENHRALFTNAGFTVDSYAYYDAAKRGVN
FDGMLASLNAAEPGTIVVLHACCHNPTGYDITAAQWDQVIAAVKAKDLVAFLDMAYQGFGHGIAEDGAVIGKFVAAGLDF
FVSTSFSKSFSLYGERVGALSVLCESKEEAARVLSQLKIVIRTNYSNPPIHGGAVVAAVLNNPELHALWEQELGEMRVRI
KAMRQKLVDGLKAAGVKQDMSFITTQIGMFSYSGLSKDQMVRLRNEFGVYGTDTGRMCVAALNSKNIDYVCASIAKVM

Sequences:

>Translated_398_residues
MSLFTAVEMAPRDPILGLNEQFNADTNPAKVNLGVGVYFDDNGKLPLLQCVQAAEKTMMATPSPRGYLPIDGIAAYDAAV
KGLVFGADSEPVTSGRIATVQGIGGTGGLKIGADFLKHLNPNAKVLISDPSWENHRALFTNAGFTVDSYAYYDAAKRGVN
FDGMLASLNAAEPGTIVVLHACCHNPTGYDITAAQWDQVIAAVKAKDLVAFLDMAYQGFGHGIAEDGAVIGKFVAAGLDF
FVSTSFSKSFSLYGERVGALSVLCESKEEAARVLSQLKIVIRTNYSNPPIHGGAVVAAVLNNPELHALWEQELGEMRVRI
KAMRQKLVDGLKAAGVKQDMSFITTQIGMFSYSGLSKDQMVRLRNEFGVYGTDTGRMCVAALNSKNIDYVCASIAKVM
>Mature_397_residues
SLFTAVEMAPRDPILGLNEQFNADTNPAKVNLGVGVYFDDNGKLPLLQCVQAAEKTMMATPSPRGYLPIDGIAAYDAAVK
GLVFGADSEPVTSGRIATVQGIGGTGGLKIGADFLKHLNPNAKVLISDPSWENHRALFTNAGFTVDSYAYYDAAKRGVNF
DGMLASLNAAEPGTIVVLHACCHNPTGYDITAAQWDQVIAAVKAKDLVAFLDMAYQGFGHGIAEDGAVIGKFVAAGLDFF
VSTSFSKSFSLYGERVGALSVLCESKEEAARVLSQLKIVIRTNYSNPPIHGGAVVAAVLNNPELHALWEQELGEMRVRIK
AMRQKLVDGLKAAGVKQDMSFITTQIGMFSYSGLSKDQMVRLRNEFGVYGTDTGRMCVAALNSKNIDYVCASIAKVM

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=43.9393939393939, Blast_Score=346, Evalue=2e-95,
Organism=Homo sapiens, GI4504067, Length=405, Percent_Identity=42.2222222222222, Blast_Score=313, Evalue=1e-85,
Organism=Homo sapiens, GI117414139, Length=380, Percent_Identity=28.4210526315789, Blast_Score=173, Evalue=2e-43,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=50.8816120906801, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=44.9494949494949, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI71981858, Length=398, Percent_Identity=40.4522613065327, Blast_Score=341, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI25147133, Length=397, Percent_Identity=40.8060453400504, Blast_Score=312, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI17569539, Length=397, Percent_Identity=38.2871536523929, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17569537, Length=398, Percent_Identity=31.6582914572864, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=39.906103286385, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17550384, Length=264, Percent_Identity=33.7121212121212, Blast_Score=164, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=36.6995073891626, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6322743, Length=436, Percent_Identity=33.9449541284404, Blast_Score=226, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24580972, Length=398, Percent_Identity=43.9698492462312, Blast_Score=338, Evalue=6e-93,
Organism=Drosophila melanogaster, GI24580970, Length=398, Percent_Identity=43.9698492462312, Blast_Score=337, Evalue=6e-93,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=44.2455242966752, Blast_Score=332, Evalue=3e-91,
Organism=Drosophila melanogaster, GI24654046, Length=398, Percent_Identity=41.4572864321608, Blast_Score=307, Evalue=9e-84,
Organism=Drosophila melanogaster, GI19922362, Length=398, Percent_Identity=41.4572864321608, Blast_Score=306, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42567; Mature: 42436

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFTAVEMAPRDPILGLNEQFNADTNPAKVNLGVGVYFDDNGKLPLLQCVQAAEKTMMA
CCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHEEC
TPSPRGYLPIDGIAAYDAAVKGLVFGADSEPVTSGRIATVQGIGGTGGLKIGADFLKHLN
CCCCCCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCC
PNAKVLISDPSWENHRALFTNAGFTVDSYAYYDAAKRGVNFDGMLASLNAAEPGTIVVLH
CCCEEEEECCCCCCCEEEEEECCCEECCHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEE
ACCHNPTGYDITAAQWDQVIAAVKAKDLVAFLDMAYQGFGHGIAEDGAVIGKFVAAGLDF
ECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
FVSTSFSKSFSLYGERVGALSVLCESKEEAARVLSQLKIVIRTNYSNPPIHGGAVVAAVL
HHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEEEECCCCCCCCCCEEEEEEE
NNPELHALWEQELGEMRVRIKAMRQKLVDGLKAAGVKQDMSFITTQIGMFSYSGLSKDQM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHH
VRLRNEFGVYGTDTGRMCVAALNSKNIDYVCASIAKVM
HHHHHHCCCEECCCCCEEEEEECCCCHHHHHHHHHHHC
>Mature Secondary Structure 
SLFTAVEMAPRDPILGLNEQFNADTNPAKVNLGVGVYFDDNGKLPLLQCVQAAEKTMMA
CCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHEEC
TPSPRGYLPIDGIAAYDAAVKGLVFGADSEPVTSGRIATVQGIGGTGGLKIGADFLKHLN
CCCCCCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCC
PNAKVLISDPSWENHRALFTNAGFTVDSYAYYDAAKRGVNFDGMLASLNAAEPGTIVVLH
CCCEEEEECCCCCCCEEEEEECCCEECCHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEE
ACCHNPTGYDITAAQWDQVIAAVKAKDLVAFLDMAYQGFGHGIAEDGAVIGKFVAAGLDF
ECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
FVSTSFSKSFSLYGERVGALSVLCESKEEAARVLSQLKIVIRTNYSNPPIHGGAVVAAVL
HHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEEEECCCCCCCCCCEEEEEEE
NNPELHALWEQELGEMRVRIKAMRQKLVDGLKAAGVKQDMSFITTQIGMFSYSGLSKDQM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHH
VRLRNEFGVYGTDTGRMCVAALNSKNIDYVCASIAKVM
HHHHHHCCCEECCCCCEEEEEECCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]