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The map label for this gene is mcrB [H]

Identifier: 91788039

GI number: 91788039

Start: 2259933

End: 2260229

Strand: Direct

Name: mcrB [H]

Synonym: Bpro_2166

Alternate gene names: 91788039

Gene position: 2259933-2260229 (Clockwise)

Preceding gene: 91788038

Following gene: 91788040

Centisome position: 43.46

GC content: 57.24

Gene sequence:

>297_bases
ATGCCCAAAGCCGAAACCGCTGCCCTCGCCAAAGTCTTGACGGACATTCCGAACATTGGCGCGTCGATTGCGCAAGACCT
GCATTCAGTCGGTATCAACACGCCGGCGGATGTGGCACACATGGACCCGCTGGCGGTGTTTGAAGCCCTGCGCACCCCCA
TGGGCCATCGCCATGACCTCTGTGTACTCGATACCTTTATGGCAGCCAAAAAGTTCATGAACGGTGGTCCACGCCAACCT
TGGTGGGACTTTACGGCAGAGCGCAAGGCGCTGCTGGCAAAACACGATAGGAGATAA

Upstream 100 bases:

>100_bases
TTTTCCTGATCTGGAAAACCCGCAACTGTTCGTTCAGACGCTTTTGTCACAGATGGCCCGCTACACGCACGCTTGAAGTT
GCCCGGCCCAACAACTCACC

Downstream 100 bases:

>100_bases
ACATGTTTACGAAAATACTGATTGCTAACAGGGGAGAGATCGCCTGCCGCGTCATCCAGACCGCCCGCAAGATGGGCATC
AAGACCGTCGCGGTCTATTC

Product: mitomycin resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MPKAETAALAKVLTDIPNIGASIAQDLHSVGINTPADVAHMDPLAVFEALRTPMGHRHDLCVLDTFMAAKKFMNGGPRQP
WWDFTAERKALLAKHDRR

Sequences:

>Translated_98_residues
MPKAETAALAKVLTDIPNIGASIAQDLHSVGINTPADVAHMDPLAVFEALRTPMGHRHDLCVLDTFMAAKKFMNGGPRQP
WWDFTAERKALLAKHDRR
>Mature_97_residues
PKAETAALAKVLTDIPNIGASIAQDLHSVGINTPADVAHMDPLAVFEALRTPMGHRHDLCVLDTFMAAKKFMNGGPRQPW
WDFTAERKALLAKHDRR

Specific function: Involved in mitomycin resistance. May operate with mcrA or may be a type of transcriptional activator protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021725 [H]

Pfam domain/function: PF11731 Cdd1 [H]

EC number: NA

Molecular weight: Translated: 10816; Mature: 10684

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKAETAALAKVLTDIPNIGASIAQDLHSVGINTPADVAHMDPLAVFEALRTPMGHRHDL
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCH
CVLDTFMAAKKFMNGGPRQPWWDFTAERKALLAKHDRR
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PKAETAALAKVLTDIPNIGASIAQDLHSVGINTPADVAHMDPLAVFEALRTPMGHRHDL
CCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCH
CVLDTFMAAKKFMNGGPRQPWWDFTAERKALLAKHDRR
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7517396 [H]