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The map label for this gene is hsaA [H]

Identifier: 91787936

GI number: 91787936

Start: 2140442

End: 2141689

Strand: Direct

Name: hsaA [H]

Synonym: Bpro_2060

Alternate gene names: 91787936

Gene position: 2140442-2141689 (Clockwise)

Preceding gene: 91787935

Following gene: 91787937

Centisome position: 41.16

GC content: 64.26

Gene sequence:

>1248_bases
ATGAATGATTTTGTTGACCATGCCGTTCTGGCATCACCGCGTAAAAGCGAAACTGAAAGCGAAACGTTCGACGCCACGGC
GTTGATGCACAGGCTCCATGAACTCGCGCCCATGCTCAGGGCGGCAGCACGGCAGGTAGAGAGCGACGGCCGGATACCTG
AAGGGCATATCGCAGCCGTGCGAGCCACGGGGTTTTTCGATCTGGTCAAGCCCGCGGCCCACGGCGGAAGCGAGGAGCAC
TTCGATACGCTGGTCCAGGCGAATCTGATCCTCGCAAGGTACTGTGCGTCAACGGCATGGGTGTGCGGCCTGCTGGCCGC
GCATCAATGGCTGCTGGCGGGTTTTCCGGCGGCAGCTCAGGACGACGTATGGGGTGCAGACCCCAACGCGCTGATGTGCG
GCTCCTATGCCCCGGCCGCCAAGGCAACGGTGCAGGCTGGTGGCTATCGACTGAGCGGCAACTGGAGCTTCGCCAGCGGA
TGTGAAGTTGCGCAATGGGCATTCTGCGCGGCCATCGTGCCCTCAGCGGCCGACCCTGCTGTTGGCGAGCCGGCATTTCT
GCTGGTGCCGGCCTCCGACTACACGATCTCCAACACCTGGGATGTCGTCGGCCTTGCCGGAACCGGCAGCAAGACACTCG
TTCTTGACGACATCTTCGTTCCGGCGCACCGGGTTCTGACATTCGCGCAGTCGACCTCCGGTGATACGCCAGGGGCCAAG
GTCTACGCGGACACAGCCGGCTACCGGATTCCCATGCTCACCATGATCCCATCTTGCCTTGCATCCGTTGCCGTGGGCGC
AGCGCAGGGCGCATTGGACGACTACCTTGAGGCGACCGGTGGCCGTATCACGCGCGGCGCGGTGGCCGGCGCCCACCAGA
AGATGGCCGAATTTCCCACCATCCAGCTGCGCGTTGCTGACGCTGCGGCCAGTACCGATGCAGCGCAGGAGATCTTGCTG
CGGGATCTGCGACGAGTGACCGACAAGGCTTACGCAGGAAGTCCTGTGACGCAGGAAGATCGGATCCTCAGCCGGCGCGG
ACAGGCGTTCGCGGTCTCTCTGGCGCTGCGTGCTGCGGAAGCCCTGAACGCTTCGACCGGCGGACTCGGCCTGAGCATGG
CGAACCCGGTGCAGCGCGCCTGGCGCGACGCGAACGCCGTGGGGCGGCATATCAGTTTGAACTGGGACGCCGTAGGAAGC
ATGTACGGCCAGTTGGCCCTGGGCCTTCCGCCCAAGGGCCAGTACTGA

Upstream 100 bases:

>100_bases
CGCCACTCCTCTATCAGAACTCGACTTACTGCAGCTCCACGCCAGTTGCTGCCCAGTAGATCGGGGAGCGCATCGACAAC
GACCTAACCGGGAATTTCAC

Downstream 100 bases:

>100_bases
AACACCGGCCACCCAAATCGCGTGATTTTTATTACTGAAAGGAAAGGTATCAATGAACGGAAAAATTGCCCTCGAGGAGC
ATTTCGCCACCGAGGAAACA

Product: acyl-CoA dehydrogenase, C-terminal type2

Products: NA

Alternate protein names: 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MNDFVDHAVLASPRKSETESETFDATALMHRLHELAPMLRAAARQVESDGRIPEGHIAAVRATGFFDLVKPAAHGGSEEH
FDTLVQANLILARYCASTAWVCGLLAAHQWLLAGFPAAAQDDVWGADPNALMCGSYAPAAKATVQAGGYRLSGNWSFASG
CEVAQWAFCAAIVPSAADPAVGEPAFLLVPASDYTISNTWDVVGLAGTGSKTLVLDDIFVPAHRVLTFAQSTSGDTPGAK
VYADTAGYRIPMLTMIPSCLASVAVGAAQGALDDYLEATGGRITRGAVAGAHQKMAEFPTIQLRVADAAASTDAAQEILL
RDLRRVTDKAYAGSPVTQEDRILSRRGQAFAVSLALRAAEALNASTGGLGLSMANPVQRAWRDANAVGRHISLNWDAVGS
MYGQLALGLPPKGQY

Sequences:

>Translated_415_residues
MNDFVDHAVLASPRKSETESETFDATALMHRLHELAPMLRAAARQVESDGRIPEGHIAAVRATGFFDLVKPAAHGGSEEH
FDTLVQANLILARYCASTAWVCGLLAAHQWLLAGFPAAAQDDVWGADPNALMCGSYAPAAKATVQAGGYRLSGNWSFASG
CEVAQWAFCAAIVPSAADPAVGEPAFLLVPASDYTISNTWDVVGLAGTGSKTLVLDDIFVPAHRVLTFAQSTSGDTPGAK
VYADTAGYRIPMLTMIPSCLASVAVGAAQGALDDYLEATGGRITRGAVAGAHQKMAEFPTIQLRVADAAASTDAAQEILL
RDLRRVTDKAYAGSPVTQEDRILSRRGQAFAVSLALRAAEALNASTGGLGLSMANPVQRAWRDANAVGRHISLNWDAVGS
MYGQLALGLPPKGQY
>Mature_415_residues
MNDFVDHAVLASPRKSETESETFDATALMHRLHELAPMLRAAARQVESDGRIPEGHIAAVRATGFFDLVKPAAHGGSEEH
FDTLVQANLILARYCASTAWVCGLLAAHQWLLAGFPAAAQDDVWGADPNALMCGSYAPAAKATVQAGGYRLSGNWSFASG
CEVAQWAFCAAIVPSAADPAVGEPAFLLVPASDYTISNTWDVVGLAGTGSKTLVLDDIFVPAHRVLTFAQSTSGDTPGAK
VYADTAGYRIPMLTMIPSCLASVAVGAAQGALDDYLEATGGRITRGAVAGAHQKMAEFPTIQLRVADAAASTDAAQEILL
RDLRRVTDKAYAGSPVTQEDRILSRRGQAFAVSLALRAAEALNASTGGLGLSMANPVQRAWRDANAVGRHISLNWDAVGS
MYGQLALGLPPKGQY

Specific function: Catalyzes the o-hydroxylation of 3-hydroxy-9,10- seconandrost-1,3,5(10)-triene-9,17-dione (3-HSA) to 3,4-dihydroxy- 9,10-seconandrost-1,3,5(10)-triene-9,17-dione (3,4-DHSA) in the catabolism of cholesterol [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FADH(2)-utilizing monooxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 43551; Mature: 43551

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFVDHAVLASPRKSETESETFDATALMHRLHELAPMLRAAARQVESDGRIPEGHIAAV
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
RATGFFDLVKPAAHGGSEEHFDTLVQANLILARYCASTAWVCGLLAAHQWLLAGFPAAAQ
EECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DDVWGADPNALMCGSYAPAAKATVQAGGYRLSGNWSFASGCEVAQWAFCAAIVPSAADPA
CCCCCCCCCEEEECCCCCCHHHEEECCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCC
VGEPAFLLVPASDYTISNTWDVVGLAGTGSKTLVLDDIFVPAHRVLTFAQSTSGDTPGAK
CCCCEEEEEECCCCEECCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCE
VYADTAGYRIPMLTMIPSCLASVAVGAAQGALDDYLEATGGRITRGAVAGAHQKMAEFPT
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCE
IQLRVADAAASTDAAQEILLRDLRRVTDKAYAGSPVTQEDRILSRRGQAFAVSLALRAAE
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEHHHHHHHHH
ALNASTGGLGLSMANPVQRAWRDANAVGRHISLNWDAVGSMYGQLALGLPPKGQY
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MNDFVDHAVLASPRKSETESETFDATALMHRLHELAPMLRAAARQVESDGRIPEGHIAAV
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
RATGFFDLVKPAAHGGSEEHFDTLVQANLILARYCASTAWVCGLLAAHQWLLAGFPAAAQ
EECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DDVWGADPNALMCGSYAPAAKATVQAGGYRLSGNWSFASGCEVAQWAFCAAIVPSAADPA
CCCCCCCCCEEEECCCCCCHHHEEECCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCC
VGEPAFLLVPASDYTISNTWDVVGLAGTGSKTLVLDDIFVPAHRVLTFAQSTSGDTPGAK
CCCCEEEEEECCCCEECCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCE
VYADTAGYRIPMLTMIPSCLASVAVGAAQGALDDYLEATGGRITRGAVAGAHQKMAEFPT
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCE
IQLRVADAAASTDAAQEILLRDLRRVTDKAYAGSPVTQEDRILSRRGQAFAVSLALRAAE
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEHHHHHHHHH
ALNASTGGLGLSMANPVQRAWRDANAVGRHISLNWDAVGSMYGQLALGLPPKGQY
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA