Click here to switch to the map view.

The map label for this gene is tctD [H]

Identifier: 91787884

GI number: 91787884

Start: 2078867

End: 2079622

Strand: Reverse

Name: tctD [H]

Synonym: Bpro_2008

Alternate gene names: 91787884

Gene position: 2079622-2078867 (Counterclockwise)

Preceding gene: 91787889

Following gene: 91787883

Centisome position: 39.99

GC content: 64.02

Gene sequence:

>756_bases
ATGCGCCTCCTTCCTGTCAAACGGCTGTCCGGAAGCATTGGGGAAAGTGCTAATGTCCTGCCCATGACGCCGACCATGAA
ATTGCTGCTAATCGAGGACGATGCCTCCATGCAGACCGCCCTGCAGCGCGCGCTGAGCCGTCGCGGCATCGAGGTCGCCA
GCTGCACCGACGGTCGGCAGGCGCTGGCTCAATGGACCACCGTGCAGCCAGATGTGGTCGTGCTCGACCTCAGCCTGCCG
GGAATGGACGGCCTGCAGGTGCTGGAACAGGCTCGGCGCCAGGGTCTGGCCACACCCGTGCTCATCCTGACGGCCCGCGG
GACCGTGGGCGACCGCATCATCGGCCTGAACACCGGCGCGGACGACTACCTGCCCAAACCTTTTGACCTGGACGAGCTGG
AAGCCCGCCTGCGCGCGCTGAGCCGCAGGCGTCCTGCGTCGGGCACCGAATCAGGCCCTGTTCCTCAATTCGTGGGCAAC
CTGCGCTATGAAAAAGAGAGCGGCGCAATCTACCACCGTGACCAGGTCCTGGAGCTCACACCGCGCGAACTGGCCTTGCT
GCAGACGCTGATCGTCAAGCCCGGCCATGCGGTATCGAAAGAGCGGCTGTTTGAACTGGTGTTTCCGGGCGAGGCCGACG
TGCAGTACGAAGCGGTAGAAGTGGTGGTTTACCGCCTGCGCAAAAAACTCGCCCACACCGGCGTGACCCTCGTCACCCTG
CGCGGCCTGGGTTATTTGCTGAAGGTGGATGCGTGA

Upstream 100 bases:

>100_bases
GCAGGGGCAAGGCCCCCGCTGCGGCCAGCGCGGCCAGGGATTTCAAAAAGGTGTCGCGACGCATGGGTTGTCTCCTTGGA
TGTGTGGTAACCCCGCCATC

Downstream 100 bases:

>100_bases
GTACCGGCGAGCCAACCCCTTCAGACAGCAGCACAGGGCAAGGCGCGGCAACACTGGGGGCGCCGCATTTCGGCGCCGGG
CCGCCCCAAGCCGAAATAGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MRLLPVKRLSGSIGESANVLPMTPTMKLLLIEDDASMQTALQRALSRRGIEVASCTDGRQALAQWTTVQPDVVVLDLSLP
GMDGLQVLEQARRQGLATPVLILTARGTVGDRIIGLNTGADDYLPKPFDLDELEARLRALSRRRPASGTESGPVPQFVGN
LRYEKESGAIYHRDQVLELTPRELALLQTLIVKPGHAVSKERLFELVFPGEADVQYEAVEVVVYRLRKKLAHTGVTLVTL
RGLGYLLKVDA

Sequences:

>Translated_251_residues
MRLLPVKRLSGSIGESANVLPMTPTMKLLLIEDDASMQTALQRALSRRGIEVASCTDGRQALAQWTTVQPDVVVLDLSLP
GMDGLQVLEQARRQGLATPVLILTARGTVGDRIIGLNTGADDYLPKPFDLDELEARLRALSRRRPASGTESGPVPQFVGN
LRYEKESGAIYHRDQVLELTPRELALLQTLIVKPGHAVSKERLFELVFPGEADVQYEAVEVVVYRLRKKLAHTGVTLVTL
RGLGYLLKVDA
>Mature_251_residues
MRLLPVKRLSGSIGESANVLPMTPTMKLLLIEDDASMQTALQRALSRRGIEVASCTDGRQALAQWTTVQPDVVVLDLSLP
GMDGLQVLEQARRQGLATPVLILTARGTVGDRIIGLNTGADDYLPKPFDLDELEARLRALSRRRPASGTESGPVPQFVGN
LRYEKESGAIYHRDQVLELTPRELALLQTLIVKPGHAVSKERLFELVFPGEADVQYEAVEVVVYRLRKKLAHTGVTLVTL
RGLGYLLKVDA

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=39.1891891891892, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=39.6396396396396, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1789809, Length=238, Percent_Identity=33.1932773109244, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=32.3008849557522, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=34.6846846846847, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=34.0807174887892, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=33.4801762114537, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=31.981981981982, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=34.8214285714286, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=36.9565217391304, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=30.0429184549356, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=37.5, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=31.0344827586207, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790299, Length=137, Percent_Identity=34.3065693430657, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=28.82096069869, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790437, Length=113, Percent_Identity=40.7079646017699, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787487, Length=108, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=124, Percent_Identity=33.0645161290323, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27556; Mature: 27556

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLPVKRLSGSIGESANVLPMTPTMKLLLIEDDASMQTALQRALSRRGIEVASCTDGRQ
CCCCCHHHHCCCCCCCCCEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEECCCHHH
ALAQWTTVQPDVVVLDLSLPGMDGLQVLEQARRQGLATPVLILTARGTVGDRIIGLNTGA
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCC
DDYLPKPFDLDELEARLRALSRRRPASGTESGPVPQFVGNLRYEKESGAIYHRDQVLELT
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCEEECCCCCEEECCCEEEEC
PRELALLQTLIVKPGHAVSKERLFELVFPGEADVQYEAVEVVVYRLRKKLAHTGVTLVTL
HHHHHHHHHHHHCCCCCCCHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEE
RGLGYLLKVDA
CCCCEEEEECC
>Mature Secondary Structure
MRLLPVKRLSGSIGESANVLPMTPTMKLLLIEDDASMQTALQRALSRRGIEVASCTDGRQ
CCCCCHHHHCCCCCCCCCEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEECCCHHH
ALAQWTTVQPDVVVLDLSLPGMDGLQVLEQARRQGLATPVLILTARGTVGDRIIGLNTGA
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCC
DDYLPKPFDLDELEARLRALSRRRPASGTESGPVPQFVGNLRYEKESGAIYHRDQVLELT
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCEEECCCCCEEECCCEEEEC
PRELALLQTLIVKPGHAVSKERLFELVFPGEADVQYEAVEVVVYRLRKKLAHTGVTLVTL
HHHHHHHHHHHHCCCCCCCHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEE
RGLGYLLKVDA
CCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]