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The map label for this gene is galE [H]

Identifier: 91787771

GI number: 91787771

Start: 1955802

End: 1956935

Strand: Reverse

Name: galE [H]

Synonym: Bpro_1892

Alternate gene names: 91787771

Gene position: 1956935-1955802 (Counterclockwise)

Preceding gene: 91787772

Following gene: 91787769

Centisome position: 37.63

GC content: 63.84

Gene sequence:

>1134_bases
ATGAATCCGCCAGCTTTCCGGCTACCTGGAATGACTTTGGAAAAAACCACCACCATCCTGTTGACCGGGGGTGCCGGCTA
TATCGGCAGCCATACCTTTGCAGCCCTGATCGATGCGGGCTACCAACCGGTCATTCTCGACAACTTCTCGAACAGCCATC
CGGCGGTGCTGGACAGGCTGCAGCAGCTGACAGGACAACGCGTCGTGCGTGAGCGGGGCGATGTCCTGCATGCCGGTTTT
GTGGCCGAGGTATTGCGCCACTACGCATGTGAAGCCGTCATCCACTTTGCCGGCGTCAAGGCGGTCGGTGAAAGTGTTCA
ACAGCCGCTCAAGTACTACAGCAATAACGTCGGGGGCCTGGTGAGCCTGCTGCAGGCCATGGAGACAAGCGCTTGCCGCT
CAGTGGTTTTTTCCTCCAGCGCCACGGTGTACGGCGATCCGGCCAGCGTTCCCATCCATGAGCAGTTCCCGTGTGCGCCC
GAGAGTCCCTATGCCCAGACCAAGCTGATGTGTGAAGACATCCTGGCGTCCCTGGGCGCGGCCGATCCGGCCTGGCGCGT
GGGCGTGCTGCGTTACTTCAACCCGGTGGGTGCGCACCCCAGCGGCCTGATCGGCGAAAACCCGCGCGGAACGCCCAACA
ACCTGATGCCTTATGTGACCCAGGTGGCCGTCGGCAAACGCGCCAGGTTGCAGGTGTTTGGCGATGACTACCTGACGCCC
GACGGAACGGGCGTGCGCGACTACCTGCATGTGATGGATCTGGCCGAGGGCCATGTGGCCGCCGTGCAGGCGCTGCTGAC
ACGCCACCAGAGTTTTACGGTCAATCTGGGCACCGGCAAGGGAGTGAGCGTACTGGAGGTCCTGAGCGCGTTTGAGCGTG
CGAGCGGCCGGCGCGTGCCCTTTGAATTCGCGCCGCGCCGGGCCGGTGATGTGGCCCAGTATTACGCCGATGTGTCGCTG
GCCGAGGCCGTACTGGGCTGGCGCGCAACACGCACGCTTGACGACATGTGCCGTGACTCATGGCGCTGGCAGCAAACCAA
TCCCGAGGGCTACGAGGCCGGCCCGGATATTCCTCCGCGGCCAGGCCTGCGCAGCAGGCCAAACGAGCCCGCTCAGCCCG
CGGCAGTTGCCTGA

Upstream 100 bases:

>100_bases
TGGCTTCATTGCCTCCGTTTCTTTTTGTTCCTGCTTCGTTTTTTAACCCGTGCCGGCACGGCAAGGCTTTCCGTCCAGTA
GGTGCAATTTGCCCCGACCG

Downstream 100 bases:

>100_bases
GCCTCATCACGCACCTCACGATGTCACGAGGCAGACACACGGCACAGGTTCCCGCCCGCGGTCTCTCAAGCACAAACGCT
CATGAGCCGATCGGACTATT

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MNPPAFRLPGMTLEKTTTILLTGGAGYIGSHTFAALIDAGYQPVILDNFSNSHPAVLDRLQQLTGQRVVRERGDVLHAGF
VAEVLRHYACEAVIHFAGVKAVGESVQQPLKYYSNNVGGLVSLLQAMETSACRSVVFSSSATVYGDPASVPIHEQFPCAP
ESPYAQTKLMCEDILASLGAADPAWRVGVLRYFNPVGAHPSGLIGENPRGTPNNLMPYVTQVAVGKRARLQVFGDDYLTP
DGTGVRDYLHVMDLAEGHVAAVQALLTRHQSFTVNLGTGKGVSVLEVLSAFERASGRRVPFEFAPRRAGDVAQYYADVSL
AEAVLGWRATRTLDDMCRDSWRWQQTNPEGYEAGPDIPPRPGLRSRPNEPAQPAAVA

Sequences:

>Translated_377_residues
MNPPAFRLPGMTLEKTTTILLTGGAGYIGSHTFAALIDAGYQPVILDNFSNSHPAVLDRLQQLTGQRVVRERGDVLHAGF
VAEVLRHYACEAVIHFAGVKAVGESVQQPLKYYSNNVGGLVSLLQAMETSACRSVVFSSSATVYGDPASVPIHEQFPCAP
ESPYAQTKLMCEDILASLGAADPAWRVGVLRYFNPVGAHPSGLIGENPRGTPNNLMPYVTQVAVGKRARLQVFGDDYLTP
DGTGVRDYLHVMDLAEGHVAAVQALLTRHQSFTVNLGTGKGVSVLEVLSAFERASGRRVPFEFAPRRAGDVAQYYADVSL
AEAVLGWRATRTLDDMCRDSWRWQQTNPEGYEAGPDIPPRPGLRSRPNEPAQPAAVA
>Mature_377_residues
MNPPAFRLPGMTLEKTTTILLTGGAGYIGSHTFAALIDAGYQPVILDNFSNSHPAVLDRLQQLTGQRVVRERGDVLHAGF
VAEVLRHYACEAVIHFAGVKAVGESVQQPLKYYSNNVGGLVSLLQAMETSACRSVVFSSSATVYGDPASVPIHEQFPCAP
ESPYAQTKLMCEDILASLGAADPAWRVGVLRYFNPVGAHPSGLIGENPRGTPNNLMPYVTQVAVGKRARLQVFGDDYLTP
DGTGVRDYLHVMDLAEGHVAAVQALLTRHQSFTVNLGTGKGVSVLEVLSAFERASGRRVPFEFAPRRAGDVAQYYADVSL
AEAVLGWRATRTLDDMCRDSWRWQQTNPEGYEAGPDIPPRPGLRSRPNEPAQPAAVA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=52.3529411764706, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=52.3529411764706, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=52.3529411764706, Blast_Score=369, Evalue=1e-102,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=53.2934131736527, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=25.414364640884, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994969, Length=363, Percent_Identity=24.5179063360882, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=48.695652173913, Blast_Score=328, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=48.4149855907781, Blast_Score=328, Evalue=3e-90,
Organism=Saccharomyces cerevisiae, GI6319493, Length=346, Percent_Identity=48.2658959537572, Blast_Score=334, Evalue=2e-92,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=50.7288629737609, Blast_Score=355, Evalue=3e-98,
Organism=Drosophila melanogaster, GI21356223, Length=316, Percent_Identity=23.4177215189873, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 40727; Mature: 40727

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPPAFRLPGMTLEKTTTILLTGGAGYIGSHTFAALIDAGYQPVILDNFSNSHPAVLDRL
CCCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHH
QQLTGQRVVRERGDVLHAGFVAEVLRHYACEAVIHFAGVKAVGESVQQPLKYYSNNVGGL
HHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VSLLQAMETSACRSVVFSSSATVYGDPASVPIHEQFPCAPESPYAQTKLMCEDILASLGA
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
ADPAWRVGVLRYFNPVGAHPSGLIGENPRGTPNNLMPYVTQVAVGKRARLQVFGDDYLTP
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
DGTGVRDYLHVMDLAEGHVAAVQALLTRHQSFTVNLGTGKGVSVLEVLSAFERASGRRVP
CCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCC
FEFAPRRAGDVAQYYADVSLAEAVLGWRATRTLDDMCRDSWRWQQTNPEGYEAGPDIPPR
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PGLRSRPNEPAQPAAVA
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNPPAFRLPGMTLEKTTTILLTGGAGYIGSHTFAALIDAGYQPVILDNFSNSHPAVLDRL
CCCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHH
QQLTGQRVVRERGDVLHAGFVAEVLRHYACEAVIHFAGVKAVGESVQQPLKYYSNNVGGL
HHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VSLLQAMETSACRSVVFSSSATVYGDPASVPIHEQFPCAPESPYAQTKLMCEDILASLGA
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
ADPAWRVGVLRYFNPVGAHPSGLIGENPRGTPNNLMPYVTQVAVGKRARLQVFGDDYLTP
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
DGTGVRDYLHVMDLAEGHVAAVQALLTRHQSFTVNLGTGKGVSVLEVLSAFERASGRRVP
CCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCC
FEFAPRRAGDVAQYYADVSLAEAVLGWRATRTLDDMCRDSWRWQQTNPEGYEAGPDIPPR
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PGLRSRPNEPAQPAAVA
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]