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The map label for this gene is aroE [H]

Identifier: 91787726

GI number: 91787726

Start: 1908699

End: 1909676

Strand: Direct

Name: aroE [H]

Synonym: Bpro_1847

Alternate gene names: 91787726

Gene position: 1908699-1909676 (Clockwise)

Preceding gene: 91787721

Following gene: 91787727

Centisome position: 36.7

GC content: 64.52

Gene sequence:

>978_bases
ATGCATTCCACCATCCAGGGCAGCACCGATGTTTATTTGATCTCCGGCGATCCGGTGGAGCAGGTGCGTGCGCCCGAGGT
GTTCAACCTGATCTTCAGGACGCTGGGTATCAACGCGGTGCTGGTACCTGTGCATGTGCCCCTCCAGGACATCGAGGCTT
TCGTGCGCACCGCTTTCCTGGCCAAAAACATCAAGGGCATGCTGCTGACCATTCCGCACAAATCGCGGGTGATGGGCCTG
CTTGCGCGTTGCAACGACGCTGGTCGCGTGGCGGGCGCGGTGAACGGCATACGCCGCAACGCAGCGGGCGAGCTGGAAGG
CGCGCTGTTCGACGGCAAGGGTTTTGTCTTGTCGCTGGACTACTTCGGGGTGGCCTACGCCGGCAAGCGCGTGCTGATCC
TGGGCGCCGGTGGCGCAGCTGCCGCCATTGCCGTCTCGCTGGCGATGGCGGGTAGCCGCGCACCTGCCGGGATTGCACTC
TATGACCCGGCACCTGGCAAGGCGCAGGCCCTGGCAAGCCAGCTTGCTGCGGCGGCGCAGACGCCCCTGAAAAAGGTTGT
GGCCGCGACCAGCAGCGACCCGTCGGCTTATGACCTGGTGGTGAACGCGTCACCGCTGGGGCTCAGGGCTGGCGATCCGC
TGCCGTGCGATGTGTCGCGGCTGGCTCCGCATGCGGCCGTGGTGGACATCCTGATGAAGAACCAGCCGACACCGCTGGTC
CAGGCTGCCCGGGCACGGCATCTGGTCGCACAGCCCGGCTTTGAAATGCTGATCCAGCAAGCACCGGATTACCTGGCTTT
TTTTGGCTACGCCGAGGCGGCGCAAGCCGTTCGCAACAACGCCACCTTTATTCGCGAACTTCTGTATCCGGCCGCCATGC
AGGGTGAGATCAACCGCCCAGGCCAGCGCATCCCCAGCTCCGAATTTGCCAGCGTTCCAGTCCCGGGAGTCGGGGAATCA
CGACTCCCGGCCCATTGA

Upstream 100 bases:

>100_bases
CAATTTCGAAAAATCAGCTTTAAATTAAAACTTCAAACCACTAAAGTTCAGCCGAAATCTGCAAGTTAAATCGATTATCG
AACATTTAGCCCAATCCACC

Downstream 100 bases:

>100_bases
TTCCATGTTGATTCCATATTGATCCCACATTGATTTTTTTACTGACTTTCAACCCTTAGTGGAGACAACCATGCAGAAAC
GATTTGCTCTTAAAGTGATA

Product: shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MHSTIQGSTDVYLISGDPVEQVRAPEVFNLIFRTLGINAVLVPVHVPLQDIEAFVRTAFLAKNIKGMLLTIPHKSRVMGL
LARCNDAGRVAGAVNGIRRNAAGELEGALFDGKGFVLSLDYFGVAYAGKRVLILGAGGAAAAIAVSLAMAGSRAPAGIAL
YDPAPGKAQALASQLAAAAQTPLKKVVAATSSDPSAYDLVVNASPLGLRAGDPLPCDVSRLAPHAAVVDILMKNQPTPLV
QAARARHLVAQPGFEMLIQQAPDYLAFFGYAEAAQAVRNNATFIRELLYPAAMQGEINRPGQRIPSSEFASVPVPGVGES
RLPAH

Sequences:

>Translated_325_residues
MHSTIQGSTDVYLISGDPVEQVRAPEVFNLIFRTLGINAVLVPVHVPLQDIEAFVRTAFLAKNIKGMLLTIPHKSRVMGL
LARCNDAGRVAGAVNGIRRNAAGELEGALFDGKGFVLSLDYFGVAYAGKRVLILGAGGAAAAIAVSLAMAGSRAPAGIAL
YDPAPGKAQALASQLAAAAQTPLKKVVAATSSDPSAYDLVVNASPLGLRAGDPLPCDVSRLAPHAAVVDILMKNQPTPLV
QAARARHLVAQPGFEMLIQQAPDYLAFFGYAEAAQAVRNNATFIRELLYPAAMQGEINRPGQRIPSSEFASVPVPGVGES
RLPAH
>Mature_325_residues
MHSTIQGSTDVYLISGDPVEQVRAPEVFNLIFRTLGINAVLVPVHVPLQDIEAFVRTAFLAKNIKGMLLTIPHKSRVMGL
LARCNDAGRVAGAVNGIRRNAAGELEGALFDGKGFVLSLDYFGVAYAGKRVLILGAGGAAAAIAVSLAMAGSRAPAGIAL
YDPAPGKAQALASQLAAAAQTPLKKVVAATSSDPSAYDLVVNASPLGLRAGDPLPCDVSRLAPHAAVVDILMKNQPTPLV
QAARARHLVAQPGFEMLIQQAPDYLAFFGYAEAAQAVRNNATFIRELLYPAAMQGEINRPGQRIPSSEFASVPVPGVGES
RLPAH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=255, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787983, Length=263, Percent_Identity=24.3346007604563, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 33956; Mature: 33956

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSTIQGSTDVYLISGDPVEQVRAPEVFNLIFRTLGINAVLVPVHVPLQDIEAFVRTAFL
CCCCCCCCCCEEEECCCCHHHHCCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHH
AKNIKGMLLTIPHKSRVMGLLARCNDAGRVAGAVNGIRRNAAGELEGALFDGKGFVLSLD
HHCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEE
YFGVAYAGKRVLILGAGGAAAAIAVSLAMAGSRAPAGIALYDPAPGKAQALASQLAAAAQ
CCCCEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
TPLKKVVAATSSDPSAYDLVVNASPLGLRAGDPLPCDVSRLAPHAAVVDILMKNQPTPLV
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCHHH
QAARARHLVAQPGFEMLIQQAPDYLAFFGYAEAAQAVRNNATFIRELLYPAAMQGEINRP
HHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
GQRIPSSEFASVPVPGVGESRLPAH
CCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHSTIQGSTDVYLISGDPVEQVRAPEVFNLIFRTLGINAVLVPVHVPLQDIEAFVRTAFL
CCCCCCCCCCEEEECCCCHHHHCCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHH
AKNIKGMLLTIPHKSRVMGLLARCNDAGRVAGAVNGIRRNAAGELEGALFDGKGFVLSLD
HHCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEE
YFGVAYAGKRVLILGAGGAAAAIAVSLAMAGSRAPAGIALYDPAPGKAQALASQLAAAAQ
CCCCEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
TPLKKVVAATSSDPSAYDLVVNASPLGLRAGDPLPCDVSRLAPHAAVVDILMKNQPTPLV
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCHHH
QAARARHLVAQPGFEMLIQQAPDYLAFFGYAEAAQAVRNNATFIRELLYPAAMQGEINRP
HHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
GQRIPSSEFASVPVPGVGESRLPAH
CCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA