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The map label for this gene is msrA [H]

Identifier: 91787556

GI number: 91787556

Start: 1727752

End: 1728294

Strand: Direct

Name: msrA [H]

Synonym: Bpro_1674

Alternate gene names: 91787556

Gene position: 1727752-1728294 (Clockwise)

Preceding gene: 91787555

Following gene: 91787558

Centisome position: 33.22

GC content: 61.51

Gene sequence:

>543_bases
ATGCCCTCATCCCCCCAAACCATCACGCTAGGCGGCGGCTGCTTCTGGTGCACCGAGGCGGTGTACGTCAAGGTGCGAGG
CGTCACCGACGTCGAATCGGGCTACAGCAACGGCCAGGCCGAGCGCCCCAGTTACGACGACGTGTGCACCGGGCGCACCG
GCTGCAACGAGGTCGTCAAGCTGACCTATGACCCCGAGGAAATCTCGCTGCGTGAAATCCTCGAAATTTTCTTCGTGATC
CACGACCCGACCAGCCTGAACCGGCAGGGCAACGATGCGGGCACGCAGTACCGCAGCGGCATCTATTACTCGACGCCCGA
GCAAAAGCAGGTGGCCGACGACTTCATTCGCCAGGCCAGCCAGGACAAGCTGTTTGGCAATCCCATCGTGACGGAAGTGC
TGCCGCTGGCCAATTACTGGCCGGCCGAGGCCTACCACCAGGACTATTTCGAGAACAATCCCAACCAGGGCTATTGCGCC
TTTGTGGTGGGCCCGAAGGTGGAGAAGTTCCGCAAGACCTTTGCCTCGCGCGTGAAGGACTGA

Upstream 100 bases:

>100_bases
AAGGGCAAGGGGCCCCGCACGGCATTCGCGTGGCCTGCGGCGTAAGATCATCGCTCTCTTTACGACCAACGATGACCAAC
GGTTTCAAGCGGAGATTTCC

Downstream 100 bases:

>100_bases
GGGTCAAGCTGAGGGGCATACGCATTGCCTCCTGATGCGGTTCCTTCCCCCAGCGGGGGAAGGAGGAGGAAGGGGTGGGA
CATCAGGCGCCAGTTCACGG

Product: peptide methionine sulfoxide reductase

Products: NA

Alternate protein names: Protein-methionine-S-oxide reductase; Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MPSSPQTITLGGGCFWCTEAVYVKVRGVTDVESGYSNGQAERPSYDDVCTGRTGCNEVVKLTYDPEEISLREILEIFFVI
HDPTSLNRQGNDAGTQYRSGIYYSTPEQKQVADDFIRQASQDKLFGNPIVTEVLPLANYWPAEAYHQDYFENNPNQGYCA
FVVGPKVEKFRKTFASRVKD

Sequences:

>Translated_180_residues
MPSSPQTITLGGGCFWCTEAVYVKVRGVTDVESGYSNGQAERPSYDDVCTGRTGCNEVVKLTYDPEEISLREILEIFFVI
HDPTSLNRQGNDAGTQYRSGIYYSTPEQKQVADDFIRQASQDKLFGNPIVTEVLPLANYWPAEAYHQDYFENNPNQGYCA
FVVGPKVEKFRKTFASRVKD
>Mature_179_residues
PSSPQTITLGGGCFWCTEAVYVKVRGVTDVESGYSNGQAERPSYDDVCTGRTGCNEVVKLTYDPEEISLREILEIFFVIH
DPTSLNRQGNDAGTQYRSGIYYSTPEQKQVADDFIRQASQDKLFGNPIVTEVLPLANYWPAEAYHQDYFENNPNQGYCAF
VVGPKVEKFRKTFASRVKD

Specific function: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine [H]

COG id: COG0225

COG function: function code O; Peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrA Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI6912516, Length=163, Percent_Identity=39.2638036809816, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI208609995, Length=164, Percent_Identity=39.0243902439024, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI208609993, Length=113, Percent_Identity=42.4778761061947, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1790665, Length=157, Percent_Identity=37.5796178343949, Blast_Score=114, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17533973, Length=141, Percent_Identity=30.4964539007092, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320881, Length=166, Percent_Identity=43.3734939759036, Blast_Score=128, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24664627, Length=164, Percent_Identity=34.1463414634146, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24664631, Length=164, Percent_Identity=34.1463414634146, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI45553131, Length=158, Percent_Identity=33.5443037974684, Blast_Score=83, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002569 [H]

Pfam domain/function: PF01625 PMSR [H]

EC number: =1.8.4.11 [H]

Molecular weight: Translated: 20261; Mature: 20129

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSPQTITLGGGCFWCTEAVYVKVRGVTDVESGYSNGQAERPSYDDVCTGRTGCNEVVK
CCCCCCEEEECCCHHEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
LTYDPEEISLREILEIFFVIHDPTSLNRQGNDAGTQYRSGIYYSTPEQKQVADDFIRQAS
EEECCHHCCHHHHHHHHHHEECCCCCCCCCCCCCHHHHCCEEECCCCHHHHHHHHHHHHH
QDKLFGNPIVTEVLPLANYWPAEAYHQDYFENNPNQGYCAFVVGPKVEKFRKTFASRVKD
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSSPQTITLGGGCFWCTEAVYVKVRGVTDVESGYSNGQAERPSYDDVCTGRTGCNEVVK
CCCCCEEEECCCHHEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
LTYDPEEISLREILEIFFVIHDPTSLNRQGNDAGTQYRSGIYYSTPEQKQVADDFIRQAS
EEECCHHCCHHHHHHHHHHEECCCCCCCCCCCCCHHHHCCEEECCCCHHHHHHHHHHHHH
QDKLFGNPIVTEVLPLANYWPAEAYHQDYFENNPNQGYCAFVVGPKVEKFRKTFASRVKD
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA