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The map label for this gene is tolC [H]

Identifier: 91787546

GI number: 91787546

Start: 1716097

End: 1717458

Strand: Reverse

Name: tolC [H]

Synonym: Bpro_1664

Alternate gene names: 91787546

Gene position: 1717458-1716097 (Counterclockwise)

Preceding gene: 91787547

Following gene: 91787544

Centisome position: 33.03

GC content: 65.35

Gene sequence:

>1362_bases
ATGACCACGCCCAAGAAACTTCAGGCGCCAGCGGTGCCTCCTGTGATAGCGCCCCTGTCGATGGCGATTGCCCTGGCGCT
GATGGCTGTTGCCCAGCAGGCACAGGCCCAGAGTCTGGTGGAACTGTATGAATCGGCCCGTGCATTTGACGCAAGCTACC
AGTCGGCCCGGCTGCAATACGACGCCAACCTGGCCAGGGCCGAACAGGCCAAGGCCGGCATCCTGCCAACGGCGGGCCTG
GCCGCGGGAGCCTCCCGCACCGGCTTCGAAAACACCAACCCGGTGGTCGACCGCAGCTTCAACACGCAAAACGCCACGCT
GACGGCCACGCAGCCGCTGTACCGGCCCCAGAACTGGGCCACCTACGAGCAGGGCGCCCGGCAGGTAGACCAGGCAAAGG
CACAGCTTGAGACCGCCGAACAGGACCTGATCGTGCGCACCAGCCAGGCTTACTTTGATGTGCTGGCCGCGCAGGACACG
CTGGCCTTTGTGCAGGCACAAAAGGCCGCGGTGGCCGAGCAGCTGGCCTCGGCCAAGCGCAACTTCGAGGTGGGCACCTC
CACCATCACCGACACCCGCGAAGCGCAGGCCCGCTACGACCTGGTGATTGCCCAGGAGATCGCCGCCGAGAACGACCTGC
GCGTCAAGAAAATCGCGCTGGACCAGCTCGTCGGCAAAACCGAATCACAGCCCAAGGGCCTGCTGGCTCCGGTGAATTTG
CCGCCGGTGGTGCCGGCAGATGTCAATACCTGGGTGCAGCAGTCCGAAGCGGTGCACCCCGGCATTCGCCTGGCGCAAAG
CGGGCTGGACATTGCCGAACTCGAAGTCAAAAAAGCCGAAGCCGGCCACAAGCCCACGCTAGACGCCACCGCCAGCTACA
ACGTCACGCGCAACCCCTCAGGCACCACGCAAACCGCCCTGTCCACACGTACCAACACCAGCACTGTCGGCCTGCTGCTC
AATGTCCCGCTGTTTGCCGGCTTTGCCACGCAAAACCGCGTGAAGGAAACGCTCGCGCTGAAAGACAAGGCACGCAGCGA
CCTCGATGGCGCACGGCGCACCGTGGCCCAGAGCACGCGCACCGCCTACTTTGGCGTGCTGTCCGGCCAGGGGCAGGTCA
AGGCCCTGGAGGCGGCCGAGCTGTCCAGCCAGAGCGCGCTGGACGCCAACAAGCTGGGCTACCAGGTGGGCGTGCGCATC
AACATCGACGTGCTCAATGCGCAAAGCCAGCTGTTCCAGACCAAGCGCGACCTGGCCCAGGCGCGCTACAACGTGCTGCT
GGGCGGCCTGCGCCTGCGGCAAGCCAACGGCACCTTGACGCCAGAGGACTTGCGGCAGATCAACGGGCTGCTGGTCAAAT
AG

Upstream 100 bases:

>100_bases
GTGCCGCTTTACTGATGCACGGCTGATGCCCCGCTGAGCCGATTGCCCGCCTTCTACCTTTGCCTTCCATTTGCCGATTC
ATCACTTCTTCAGGACCCTT

Downstream 100 bases:

>100_bases
CCAACGGCAAATAGCAAGTAGCAAGTAGCAAGTACCAAGTACCAAGTGCCCAACAAACAAGGCAAGGGCCGATAAGGCCA
CGTACGTTACTTCCCTTTGT

Product: Type I secretion outer membrane protein TolC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MTTPKKLQAPAVPPVIAPLSMAIALALMAVAQQAQAQSLVELYESARAFDASYQSARLQYDANLARAEQAKAGILPTAGL
AAGASRTGFENTNPVVDRSFNTQNATLTATQPLYRPQNWATYEQGARQVDQAKAQLETAEQDLIVRTSQAYFDVLAAQDT
LAFVQAQKAAVAEQLASAKRNFEVGTSTITDTREAQARYDLVIAQEIAAENDLRVKKIALDQLVGKTESQPKGLLAPVNL
PPVVPADVNTWVQQSEAVHPGIRLAQSGLDIAELEVKKAEAGHKPTLDATASYNVTRNPSGTTQTALSTRTNTSTVGLLL
NVPLFAGFATQNRVKETLALKDKARSDLDGARRTVAQSTRTAYFGVLSGQGQVKALEAAELSSQSALDANKLGYQVGVRI
NIDVLNAQSQLFQTKRDLAQARYNVLLGGLRLRQANGTLTPEDLRQINGLLVK

Sequences:

>Translated_453_residues
MTTPKKLQAPAVPPVIAPLSMAIALALMAVAQQAQAQSLVELYESARAFDASYQSARLQYDANLARAEQAKAGILPTAGL
AAGASRTGFENTNPVVDRSFNTQNATLTATQPLYRPQNWATYEQGARQVDQAKAQLETAEQDLIVRTSQAYFDVLAAQDT
LAFVQAQKAAVAEQLASAKRNFEVGTSTITDTREAQARYDLVIAQEIAAENDLRVKKIALDQLVGKTESQPKGLLAPVNL
PPVVPADVNTWVQQSEAVHPGIRLAQSGLDIAELEVKKAEAGHKPTLDATASYNVTRNPSGTTQTALSTRTNTSTVGLLL
NVPLFAGFATQNRVKETLALKDKARSDLDGARRTVAQSTRTAYFGVLSGQGQVKALEAAELSSQSALDANKLGYQVGVRI
NIDVLNAQSQLFQTKRDLAQARYNVLLGGLRLRQANGTLTPEDLRQINGLLVK
>Mature_452_residues
TTPKKLQAPAVPPVIAPLSMAIALALMAVAQQAQAQSLVELYESARAFDASYQSARLQYDANLARAEQAKAGILPTAGLA
AGASRTGFENTNPVVDRSFNTQNATLTATQPLYRPQNWATYEQGARQVDQAKAQLETAEQDLIVRTSQAYFDVLAAQDTL
AFVQAQKAAVAEQLASAKRNFEVGTSTITDTREAQARYDLVIAQEIAAENDLRVKKIALDQLVGKTESQPKGLLAPVNLP
PVVPADVNTWVQQSEAVHPGIRLAQSGLDIAELEVKKAEAGHKPTLDATASYNVTRNPSGTTQTALSTRTNTSTVGLLLN
VPLFAGFATQNRVKETLALKDKARSDLDGARRTVAQSTRTAYFGVLSGQGQVKALEAAELSSQSALDANKLGYQVGVRIN
IDVLNAQSQLFQTKRDLAQARYNVLLGGLRLRQANGTLTPEDLRQINGLLVK

Specific function: May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=429, Percent_Identity=32.1678321678322, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 48616; Mature: 48485

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPKKLQAPAVPPVIAPLSMAIALALMAVAQQAQAQSLVELYESARAFDASYQSARLQY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEE
DANLARAEQAKAGILPTAGLAAGASRTGFENTNPVVDRSFNTQNATLTATQPLYRPQNWA
CCCHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCEECCCCCCCCEEEECCCCCCCCCCC
TYEQGARQVDQAKAQLETAEQDLIVRTSQAYFDVLAAQDTLAFVQAQKAAVAEQLASAKR
HHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NFEVGTSTITDTREAQARYDLVIAQEIAAENDLRVKKIALDQLVGKTESQPKGLLAPVNL
CCCCCCCCCCCCHHHHHHHHHEHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEECCCC
PPVVPADVNTWVQQSEAVHPGIRLAQSGLDIAELEVKKAEAGHKPTLDATASYNVTRNPS
CCCCCCCHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCC
GTTQTALSTRTNTSTVGLLLNVPLFAGFATQNRVKETLALKDKARSDLDGARRTVAQSTR
CCCHHHEECCCCCCEEEEEEECHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAYFGVLSGQGQVKALEAAELSSQSALDANKLGYQVGVRINIDVLNAQSQLFQTKRDLAQ
HEEEEEECCCCCEEEHHHHHHCCHHCCCHHHCCEEEEEEEEEEEECCHHHHHHHHHHHHH
ARYNVLLGGLRLRQANGTLTPEDLRQINGLLVK
HHHHHHHCCEEEEECCCCCCHHHHHHHCCEECC
>Mature Secondary Structure 
TTPKKLQAPAVPPVIAPLSMAIALALMAVAQQAQAQSLVELYESARAFDASYQSARLQY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEE
DANLARAEQAKAGILPTAGLAAGASRTGFENTNPVVDRSFNTQNATLTATQPLYRPQNWA
CCCHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCEECCCCCCCCEEEECCCCCCCCCCC
TYEQGARQVDQAKAQLETAEQDLIVRTSQAYFDVLAAQDTLAFVQAQKAAVAEQLASAKR
HHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NFEVGTSTITDTREAQARYDLVIAQEIAAENDLRVKKIALDQLVGKTESQPKGLLAPVNL
CCCCCCCCCCCCHHHHHHHHHEHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEECCCC
PPVVPADVNTWVQQSEAVHPGIRLAQSGLDIAELEVKKAEAGHKPTLDATASYNVTRNPS
CCCCCCCHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCC
GTTQTALSTRTNTSTVGLLLNVPLFAGFATQNRVKETLALKDKARSDLDGARRTVAQSTR
CCCHHHEECCCCCCEEEEEEECHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAYFGVLSGQGQVKALEAAELSSQSALDANKLGYQVGVRINIDVLNAQSQLFQTKRDLAQ
HEEEEEECCCCCEEEHHHHHHCCHHCCCHHHCCEEEEEEEEEEEECCHHHHHHHHHHHHH
ARYNVLLGGLRLRQANGTLTPEDLRQINGLLVK
HHHHHHHCCEEEEECCCCCCHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]