Click here to switch to the map view.

The map label for this gene is pgm [H]

Identifier: 91787521

GI number: 91787521

Start: 1694039

End: 1695424

Strand: Direct

Name: pgm [H]

Synonym: Bpro_1639

Alternate gene names: 91787521

Gene position: 1694039-1695424 (Clockwise)

Preceding gene: 91787517

Following gene: 91787522

Centisome position: 32.58

GC content: 64.5

Gene sequence:

>1386_bases
ATGCAAGTCAGCGCATCCATTTTCAAGGCCTATGACATTCGCGGCGTCGTGCCGTCCACCATCAACGATGAGATGGCCGA
GGCCCTTGGAAAAGCCTTTGGCACGGTGGCGTTGGCGGAAGGGGAGAAAACCGTGGCCGTGGGCCGCGACGGCCGGCTCA
GCGGGCCCTCGCTCAGCGCGGCGCTCATGCGCGGCCTGGCAGCATCCGGCGTCAATGTGATCGATGTCGGCATGGTCACC
ACGCCCATGCTGTATTTCGCGGCCAACACCCTGGCCACCTCCGGCATCCAGGTCACCGGCAGCCACAACCCCAAGGACTA
CAACGGCTTCAAGATGGTGCTGGCCGGCCGGGCGATTTACGGTGAAGACATCCAGGCCCTGCGCCGCCTGATCGAATCGG
AAGGCTGGGCGCAGCCGGCGCAGGGCGGCACCATCAGCCGCGTCGATGTTGAAAAGGATTACCGCGACCGCATCGTTTCC
GGCATCAAGCTGGAGCGGCCGCTGAAGATCGTCATCGACTCAGGCAATGGCATTGCCGGTGCCTCGGCCCCCGCCATTTT
TCGGGCCCTGGGGTGCGAAGTGACCGAGCTGTTCAGCGAAGTCGACGGCAACTTTCCCAACCACCACCCCGACCCGAGCA
AACCCGAGAACCTGCAGGACTTGATCAAGGCGCTGCAAAGCGGCAACGCAGAACTGGGCCTGGCGTTTGACGGCGACGGC
GACCGGCTGGGCATTGTGACCAAAGACGGGCAGAACATCTACCCCGACCGGCAGATGATGCTGTTTGCGCGCGACGTGCT
GTCGCGCGTGCCGGGCGGCACGATCCTGTTCGACGTGAAGTGCTCGCAGCGCCTGGCGCCCGAGATCGAGGCGGCCGGCG
GCGTGCCGCTGATGTACAAGACCGGCCACTCGCTGATCAAGGCCAAGATGAAGGAAATCAATTCGCCGCTGGGCGGCGAG
ATGAGCGGCCACATCTTCTTCAAGGAGCGCTGGTTTGGTTTTGATGACGGCACCTACGCCGGTGCACGCCTGCTCGAGAT
CCTAAGCCGCGTGCCGGATGCGGGCATCCTTCTCAACGGCCTGCCCACCAGTTTCAGCACGCCGGAGCTTAACGTCGCCT
GCAAGGAAGGCGAGCCCCACACCGTGGTGGAAGCACTGACCAAAGCCGCCCACTTTCCGGCACCCGCCAAAATCTCCACC
ATCGACGGCATCCGCGTGGACTGGCCCGATGGCTTTGGCCTCATTCGCGCTTCCAACACCACGCCGGTGCTGGTGCTCCG
CTTCGAGGGCCACACGCAGCAGGCGCTGGAGCGCATCGAGGCCGACATGCTCGCGCTGTTGCGCAGCGTGAAGCCCGACG
CCAGCTTCGCCGCCGCGGCACATTAG

Upstream 100 bases:

>100_bases
AGCCGTTTTCGGACATATCCCTCAAGCCCGCCGGGGCCCGTCCCGAGGGAGGGCGCCACCCTACAATCGACTCACTTCAA
CTTTCAGTGAACCCCCGCCC

Downstream 100 bases:

>100_bases
AGATGGTGCCCCCACGCTCGTCACTTCGTGTACTTCGCTGCCCCCTCAAGGGGCTGGCCTTGCTTGGGGCGGCCCGGCGC
GGCGGCCTGCCGGCTGGCGC

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MQVSASIFKAYDIRGVVPSTINDEMAEALGKAFGTVALAEGEKTVAVGRDGRLSGPSLSAALMRGLAASGVNVIDVGMVT
TPMLYFAANTLATSGIQVTGSHNPKDYNGFKMVLAGRAIYGEDIQALRRLIESEGWAQPAQGGTISRVDVEKDYRDRIVS
GIKLERPLKIVIDSGNGIAGASAPAIFRALGCEVTELFSEVDGNFPNHHPDPSKPENLQDLIKALQSGNAELGLAFDGDG
DRLGIVTKDGQNIYPDRQMMLFARDVLSRVPGGTILFDVKCSQRLAPEIEAAGGVPLMYKTGHSLIKAKMKEINSPLGGE
MSGHIFFKERWFGFDDGTYAGARLLEILSRVPDAGILLNGLPTSFSTPELNVACKEGEPHTVVEALTKAAHFPAPAKIST
IDGIRVDWPDGFGLIRASNTTPVLVLRFEGHTQQALERIEADMLALLRSVKPDASFAAAAH

Sequences:

>Translated_461_residues
MQVSASIFKAYDIRGVVPSTINDEMAEALGKAFGTVALAEGEKTVAVGRDGRLSGPSLSAALMRGLAASGVNVIDVGMVT
TPMLYFAANTLATSGIQVTGSHNPKDYNGFKMVLAGRAIYGEDIQALRRLIESEGWAQPAQGGTISRVDVEKDYRDRIVS
GIKLERPLKIVIDSGNGIAGASAPAIFRALGCEVTELFSEVDGNFPNHHPDPSKPENLQDLIKALQSGNAELGLAFDGDG
DRLGIVTKDGQNIYPDRQMMLFARDVLSRVPGGTILFDVKCSQRLAPEIEAAGGVPLMYKTGHSLIKAKMKEINSPLGGE
MSGHIFFKERWFGFDDGTYAGARLLEILSRVPDAGILLNGLPTSFSTPELNVACKEGEPHTVVEALTKAAHFPAPAKIST
IDGIRVDWPDGFGLIRASNTTPVLVLRFEGHTQQALERIEADMLALLRSVKPDASFAAAAH
>Mature_461_residues
MQVSASIFKAYDIRGVVPSTINDEMAEALGKAFGTVALAEGEKTVAVGRDGRLSGPSLSAALMRGLAASGVNVIDVGMVT
TPMLYFAANTLATSGIQVTGSHNPKDYNGFKMVLAGRAIYGEDIQALRRLIESEGWAQPAQGGTISRVDVEKDYRDRIVS
GIKLERPLKIVIDSGNGIAGASAPAIFRALGCEVTELFSEVDGNFPNHHPDPSKPENLQDLIKALQSGNAELGLAFDGDG
DRLGIVTKDGQNIYPDRQMMLFARDVLSRVPGGTILFDVKCSQRLAPEIEAAGGVPLMYKTGHSLIKAKMKEINSPLGGE
MSGHIFFKERWFGFDDGTYAGARLLEILSRVPDAGILLNGLPTSFSTPELNVACKEGEPHTVVEALTKAAHFPAPAKIST
IDGIRVDWPDGFGLIRASNTTPVLVLRFEGHTQQALERIEADMLALLRSVKPDASFAAAAH

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=441, Percent_Identity=36.281179138322, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI1789566, Length=454, Percent_Identity=29.295154185022, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 49226; Mature: 49226

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSASIFKAYDIRGVVPSTINDEMAEALGKAFGTVALAEGEKTVAVGRDGRLSGPSLSA
CCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCCCHHH
ALMRGLAASGVNVIDVGMVTTPMLYFAANTLATSGIQVTGSHNPKDYNGFKMVLAGRAIY
HHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCC
GEDIQALRRLIESEGWAQPAQGGTISRVDVEKDYRDRIVSGIKLERPLKIVIDSGNGIAG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCEECCCEEEEEECCCCCCC
ASAPAIFRALGCEVTELFSEVDGNFPNHHPDPSKPENLQDLIKALQSGNAELGLAFDGDG
CCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
DRLGIVTKDGQNIYPDRQMMLFARDVLSRVPGGTILFDVKCSQRLAPEIEAAGGVPLMYK
CEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCCCCEEEEC
TGHSLIKAKMKEINSPLGGEMSGHIFFKERWFGFDDGTYAGARLLEILSRVPDAGILLNG
CCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEC
LPTSFSTPELNVACKEGEPHTVVEALTKAAHFPAPAKISTIDGIRVDWPDGFGLIRASNT
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEECCCCCEEEEECCC
TPVLVLRFEGHTQQALERIEADMLALLRSVKPDASFAAAAH
CEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure
MQVSASIFKAYDIRGVVPSTINDEMAEALGKAFGTVALAEGEKTVAVGRDGRLSGPSLSA
CCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCCCHHH
ALMRGLAASGVNVIDVGMVTTPMLYFAANTLATSGIQVTGSHNPKDYNGFKMVLAGRAIY
HHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCC
GEDIQALRRLIESEGWAQPAQGGTISRVDVEKDYRDRIVSGIKLERPLKIVIDSGNGIAG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCEECCCEEEEEECCCCCCC
ASAPAIFRALGCEVTELFSEVDGNFPNHHPDPSKPENLQDLIKALQSGNAELGLAFDGDG
CCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
DRLGIVTKDGQNIYPDRQMMLFARDVLSRVPGGTILFDVKCSQRLAPEIEAAGGVPLMYK
CEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCCCCEEEEC
TGHSLIKAKMKEINSPLGGEMSGHIFFKERWFGFDDGTYAGARLLEILSRVPDAGILLNG
CCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEC
LPTSFSTPELNVACKEGEPHTVVEALTKAAHFPAPAKISTIDGIRVDWPDGFGLIRASNT
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEECCCCCEEEEECCC
TPVLVLRFEGHTQQALERIEADMLALLRSVKPDASFAAAAH
CEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]