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The map label for this gene is paaG [C]

Identifier: 91787515

GI number: 91787515

Start: 1687933

End: 1688733

Strand: Direct

Name: paaG [C]

Synonym: Bpro_1633

Alternate gene names: 91787515

Gene position: 1687933-1688733 (Clockwise)

Preceding gene: 91787514

Following gene: 91787516

Centisome position: 32.46

GC content: 68.54

Gene sequence:

>801_bases
ATGAGCCGCAGAATCGACATCGCGCCCCATCTGCATGCGGAGATCGGCGACAACGGCGTGGCTGAACTGGTGTTGGGTCC
CGAGGGTGGCATGCCCACCACCGACGCCCAGGGTCATGCCGCGCTTGGCACCGTCTGGGCGCAGCTGGCGGCCGAGCCCG
GCGTGCGCTGCATCCTGGTGCGCAGTGTCGGCAAGGGCTTTTGCGCGGGCGGCACGCTCGACCTCGTGCAGGACATGCTG
GGCAGCGAATCCGCACGCCTGCGCGTGATGCGGGAAGGCCGCGCCATCGTGCAGGGCATGATCGACTGTGATGTGCCCAT
CGTCACGGCCATCAACGGCGCGGCGGTAGGCGCGGGTGCGGCGGTGGCCTTGCTGGCCGATGTGTCCATCGCGGGCCACA
AAGCCAAAATCATCGACGGCCACACCAAACTCGGCGTGGCCGCCGGCGATCATGCCGCGCTCATCTGGCCCTTGCTGTGC
GGCATGGCCCGTGCCAAGTACCACTTGCTGATGTGTTCCACGCTCGACGGCATTGAGGCCGAACGCATCGGCCTGGTCAG
CCTGGCGGTGCCCGACGACCAGTTGCTGGACAAGGCGCGTGAGGTGGCCCGCACGCTGGCCGCCGGCAGCCCCACGGCAT
TGGCTTTCACCAAGCGCAGCCTGAACCACTGGCTGCGCGCGGCCTGGCCCGCCTTCGAGCATTCCCTGGCGCTGGAGATG
CTGGGCTTTGCCGGCGCCGACGCGCGTGAGGGCTTCGCGGCACTGAACGAAAAACGTGCACCGCGCTTCGCCCCGGACTG
A

Upstream 100 bases:

>100_bases
ACGTCATTGGCTGTTTAGACGCGCTGGACGCGCATTACCGTGGCGAGCGCTACCGCGTCAGCCCCTGGCTGCGCCAACGG
GCCTGGCAGGAGGGTGTGCA

Downstream 100 bases:

>100_bases
TTCGGCATGAAATTCGCCGGGTAATTCGCCGAGTTCCAGACCGGGCAGATTCTTCAGGCCGGATCCAAGATCCCGCGGCG
GTATGACTGGCGAGCCGCCA

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MSRRIDIAPHLHAEIGDNGVAELVLGPEGGMPTTDAQGHAALGTVWAQLAAEPGVRCILVRSVGKGFCAGGTLDLVQDML
GSESARLRVMREGRAIVQGMIDCDVPIVTAINGAAVGAGAAVALLADVSIAGHKAKIIDGHTKLGVAAGDHAALIWPLLC
GMARAKYHLLMCSTLDGIEAERIGLVSLAVPDDQLLDKAREVARTLAAGSPTALAFTKRSLNHWLRAAWPAFEHSLALEM
LGFAGADAREGFAALNEKRAPRFAPD

Sequences:

>Translated_266_residues
MSRRIDIAPHLHAEIGDNGVAELVLGPEGGMPTTDAQGHAALGTVWAQLAAEPGVRCILVRSVGKGFCAGGTLDLVQDML
GSESARLRVMREGRAIVQGMIDCDVPIVTAINGAAVGAGAAVALLADVSIAGHKAKIIDGHTKLGVAAGDHAALIWPLLC
GMARAKYHLLMCSTLDGIEAERIGLVSLAVPDDQLLDKAREVARTLAAGSPTALAFTKRSLNHWLRAAWPAFEHSLALEM
LGFAGADAREGFAALNEKRAPRFAPD
>Mature_265_residues
SRRIDIAPHLHAEIGDNGVAELVLGPEGGMPTTDAQGHAALGTVWAQLAAEPGVRCILVRSVGKGFCAGGTLDLVQDMLG
SESARLRVMREGRAIVQGMIDCDVPIVTAINGAAVGAGAAVALLADVSIAGHKAKIIDGHTKLGVAAGDHAALIWPLLCG
MARAKYHLLMCSTLDGIEAERIGLVSLAVPDDQLLDKAREVARTLAAGSPTALAFTKRSLNHWLRAAWPAFEHSLALEML
GFAGADAREGFAALNEKRAPRFAPD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4502327, Length=224, Percent_Identity=31.6964285714286, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI194097323, Length=230, Percent_Identity=25.2173913043478, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787660, Length=254, Percent_Identity=31.1023622047244, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787659, Length=163, Percent_Identity=33.7423312883436, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788597, Length=211, Percent_Identity=27.0142180094787, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI221142681, Length=242, Percent_Identity=26.4462809917355, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=160, Percent_Identity=33.125, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=166, Percent_Identity=28.3132530120482, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=237, Percent_Identity=26.5822784810127, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24653477, Length=237, Percent_Identity=26.5822784810127, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24653139, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27728; Mature: 27597

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRIDIAPHLHAEIGDNGVAELVLGPEGGMPTTDAQGHAALGTVWAQLAAEPGVRCILV
CCCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEE
RSVGKGFCAGGTLDLVQDMLGSESARLRVMREGRAIVQGMIDCDVPIVTAINGAAVGAGA
EECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHH
AVALLADVSIAGHKAKIIDGHTKLGVAAGDHAALIWPLLCGMARAKYHLLMCSTLDGIEA
HHHHHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCH
ERIGLVSLAVPDDQLLDKAREVARTLAAGSPTALAFTKRSLNHWLRAAWPAFEHSLALEM
HHEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFAGADAREGFAALNEKRAPRFAPD
HHCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SRRIDIAPHLHAEIGDNGVAELVLGPEGGMPTTDAQGHAALGTVWAQLAAEPGVRCILV
CCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEE
RSVGKGFCAGGTLDLVQDMLGSESARLRVMREGRAIVQGMIDCDVPIVTAINGAAVGAGA
EECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHH
AVALLADVSIAGHKAKIIDGHTKLGVAAGDHAALIWPLLCGMARAKYHLLMCSTLDGIEA
HHHHHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCH
ERIGLVSLAVPDDQLLDKAREVARTLAAGSPTALAFTKRSLNHWLRAAWPAFEHSLALEM
HHEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFAGADAREGFAALNEKRAPRFAPD
HHCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA